![]()
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | ISO | RGD:1314165 | 6480464 | ethylene dichloride results in decreased expression of NAALAD2 mRNA | CTD | PMID:28960355 | 17alpha-ethynylestradiol | affects expression | ISO | RGD:1314165 | 6480464 | Ethinyl Estradiol affects the expression of NAALAD2 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1314165 | 6480464 | Ethinyl Estradiol results in increased expression of NAALAD2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1314165 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NAALAD2 mRNA | CTD | PMID:28213091 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NAALAD2 mRNA | CTD | PMID:33387578 | 4-nonylphenol | multiple interactions | ISO | RGD:1314164 | 6480464 | [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of NAALAD2 mRNA | CTD | PMID:23626723 | 4-tert-Octylphenol | multiple interactions | ISO | RGD:1314164 | 6480464 | [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of NAALAD2 mRNA | CTD | PMID:23626723 | acrylamide | increases expression | ISO | RGD:1314164 | 6480464 | Acrylamide results in increased expression of NAALAD2 mRNA | CTD | PMID:32763439 | aflatoxin B1 | decreases methylation | ISO | RGD:1314164 | 6480464 | Aflatoxin B1 results in decreased methylation of NAALAD2 gene | CTD | PMID:27153756 | aflatoxin M1 | decreases expression | ISO | RGD:1314164 | 6480464 | Aflatoxin M1 results in decreased expression of NAALAD2 mRNA | CTD | PMID:30928695 | aristolochic acid A | increases expression | ISO | RGD:1314164 | 6480464 | aristolochic acid I results in increased expression of NAALAD2 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | decreases expression | ISO | RGD:1314164 | 6480464 | Benzo(a)pyrene results in decreased expression of NAALAD2 mRNA | CTD | PMID:20106945 | benzo[a]pyrene | increases methylation | ISO | RGD:1314164 | 6480464 | Benzo(a)pyrene results in increased methylation of NAALAD2 5' UTR, Benzo(a)pyrene results in increased methylation of NAALAD2 exon | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | RGD:1314164 | 6480464 | Benzo(a)pyrene affects the methylation of NAALAD2 promoter | CTD | PMID:27901495 | beta-naphthoflavone | decreases expression | ISO | RGD:1314164 | 6480464 | beta-Naphthoflavone results in decreased expression of NAALAD2 mRNA | CTD | PMID:32858204 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | RGD:1314164 | 6480464 | Diethylhexyl Phthalate results in decreased expression of NAALAD2 mRNA | CTD | PMID:31163220 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of NAALAD2 gene | CTD | PMID:28505145 | bisphenol A | multiple interactions | ISO | RGD:1314164 | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of NAALAD2 gene | CTD | PMID:31601247 | CGP 52608 | multiple interactions | ISO | RGD:1314164 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to NAALAD2 gene] | CTD | PMID:28238834 | clofibrate | increases expression | ISO | RGD:1314165 | 6480464 | Clofibrate results in increased expression of NAALAD2 mRNA | CTD | PMID:17585979 | copper(II) sulfate | decreases expression | ISO | RGD:1314164 | 6480464 | Copper Sulfate results in decreased expression of NAALAD2 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | RGD:1314164 | 6480464 | Cyclosporine results in decreased expression of NAALAD2 mRNA | CTD | PMID:20106945, PMID:25562108 | D-mannitol | increases expression | ISO | RGD:1314165 | 6480464 | Mannitol results in increased expression of NAALAD2 mRNA | CTD | PMID:25270620 | dicrotophos | decreases expression | ISO | RGD:1314164 | 6480464 | dicrotophos results in decreased expression of NAALAD2 mRNA | CTD | PMID:28302478 | dorsomorphin | multiple interactions | ISO | RGD:1314164 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of NAALAD2 mRNA | CTD | PMID:29391264 | entinostat | multiple interactions | ISO | RGD:1314164 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NAALAD2 mRNA | CTD | PMID:27188386 | entinostat | decreases expression | ISO | RGD:1314164 | 6480464 | entinostat results in decreased expression of NAALAD2 mRNA | CTD | PMID:26272509 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of NAALAD2 protein | CTD | PMID:33656234 | folic acid | decreases expression | ISO | RGD:1314164 | 6480464 | Folic Acid results in decreased expression of NAALAD2 mRNA | CTD | PMID:21867686 | fulvestrant | multiple interactions | ISO | RGD:1314164 | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of NAALAD2 gene | CTD | PMID:31601247 | mercury dichloride | multiple interactions | ISO | RGD:1314164 | 6480464 | [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NAALAD2 mRNA | CTD | PMID:27188386 | methylmercury chloride | decreases expression | ISO | RGD:1314164 | 6480464 | methylmercuric chloride results in decreased expression of NAALAD2 mRNA | CTD | PMID:23179753 more ... | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of NAALAD2 gene | CTD | PMID:33148267 | nickel atom | decreases expression | ISO | RGD:1314164 | 6480464 | Nickel results in decreased expression of NAALAD2 mRNA | CTD | PMID:25583101 | ozone | multiple interactions | ISO | RGD:1314165 | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of NAALAD2 mRNA | CTD | PMID:34911549 | p-tert-Amylphenol | multiple interactions | ISO | RGD:1314164 | 6480464 | [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of NAALAD2 mRNA | CTD | PMID:23626723 | paracetamol | decreases expression | ISO | RGD:1314164 | 6480464 | Acetaminophen results in decreased expression of NAALAD2 mRNA | CTD | PMID:29067470 | perfluorooctanoic acid | decreases expression | ISO | RGD:1314164 | 6480464 | perfluorooctanoic acid results in decreased expression of NAALAD2 protein | CTD | PMID:26879310 | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of NAALAD2 gene | CTD | PMID:33148267 | pioglitazone | multiple interactions | ISO | RGD:1314165 | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NAALAD2 mRNA | CTD | PMID:27935865 | quercetin | decreases expression | ISO | RGD:1314164 | 6480464 | Quercetin results in decreased expression of NAALAD2 mRNA | CTD | PMID:21632981 | SB 431542 | multiple interactions | ISO | RGD:1314164 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | RGD:1314164 | 6480464 | Silicon Dioxide results in increased expression of NAALAD2 mRNA | CTD | PMID:25351596 | tamoxifen | affects expression | ISO | RGD:1314165 | 6480464 | Tamoxifen affects the expression of NAALAD2 mRNA | CTD | PMID:17555576 | tetrachloromethane | affects expression | ISO | RGD:1314165 | 6480464 | Carbon Tetrachloride affects the expression of NAALAD2 mRNA | CTD | PMID:17484886 | trichloroethene | decreases methylation | EXP | | 6480464 | Trichloroethylene results in decreased methylation of NAALAD2 gene | CTD | PMID:27618143 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of NAALAD2 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | RGD:1314164 | 6480464 | trichostatin A results in increased expression of NAALAD2 mRNA | CTD | PMID:24935251 | trichostatin A | multiple interactions | ISO | RGD:1314164 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NAALAD2 mRNA | CTD | PMID:27188386 | trichostatin A | decreases expression | ISO | RGD:1314164 | 6480464 | trichostatin A results in decreased expression of NAALAD2 mRNA | CTD | PMID:24935251, PMID:26272509 | urethane | decreases expression | ISO | RGD:1314164 | 6480464 | Urethane results in decreased expression of NAALAD2 mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | RGD:1314164 | 6480464 | Valproic Acid results in decreased expression of NAALAD2 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | RGD:1314164 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NAALAD2 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | RGD:1314164 | 6480464 | Valproic Acid results in increased expression of NAALAD2 mRNA | CTD | PMID:23179753 more ... | |