RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: pulmonary eosinophilia
Accession: DOID:9498
browse the term
Definition: A hypereosinophilic syndrome characterized by the accumulation of eosinophils in the lungs. (DO)
Synonyms: exact_synonym: Eosinophilic Pneumonia; Simple Pulmonary Eosinophilia; Simple Pulmonary Eosinophilias; eosinophilic pneumonias; pulmonary eosinophilias; tropical eosinophilic pneumonia; tropical eosinophilic pneumonias
primary_id: MESH:D011657
xref: ICD9CM:518.3
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Adam8
ADAM metallopeptidase domain 8
ISO
protein:increased expression:serum
RGD
PMID:19625177
RGD:5128874
NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
G
C3
complement C3
ISO
RGD
PMID:23549917
RGD:7401272
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
G
Ccl1
C-C motif chemokine ligand 1
ISO
associated with Asthma
RGD
PMID:12707363
RGD:4891412
NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159
G
Ccl11
C-C motif chemokine ligand 11
ISO
RGD
PMID:12750406
RGD:4145437
NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
G
Ccl17
C-C motif chemokine ligand 17
ISO
protein:increased expression:respiratory system fluid/secretion
RGD
PMID:11956056
RGD:4145602
NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819
G
Ccr3
C-C motif chemokine receptor 3
ISO
RGD
PMID:20732990
RGD:4145617
NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
G
Cd44
CD44 molecule
ISO
RGD
PMID:12750406
RGD:4145437
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620
G
Epas1
endothelial PAS domain protein 1
ISO
RGD
PMID:24218148
RGD:11041569
NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
G
Il10
interleukin 10
ISO
protein:increased expression:lung
RGD
PMID:20796249
RGD:4140455
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il13
interleukin 13
ISO
associated with Respiratory Syncytial Virus Infections
RGD
PMID:12574374
RGD:8549597
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
G
Il1rn
interleukin 1 receptor antagonist
ISO
protein:increased expression:Bronchoalveolar lavage:
RGD
PMID:24706315
RGD:11528542
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
G
Il5
interleukin 5
treatment
ISO
associated with respiratory syncytial virus infection protein:increased expression:respiratory system fluid/secretion associated with Pulmonary Fibrosis;protein:increased expression:respiratory system fluid/secretion
RGD
PMID:9712797 PMID:18519743 PMID:12765419 PMID:10471622 PMID:17597386
RGD:4890961 , RGD:4890941 , RGD:4890956 , RGD:11354935 , RGD:11354949
NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
G
Itgb2
integrin subunit beta 2
ISO
protein:increased expression:lung (mouse)
RGD
PMID:7743671
RGD:8547590
NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
G
Myd88
MYD88, innate immune signal transduction adaptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29067999
NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
G
Nos2
nitric oxide synthase 2
ISO
RGD
PMID:18829681
RGD:4891506
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
G
Nos3
nitric oxide synthase 3
ISO
RGD
PMID:16714207
RGD:4892061
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
G
Scgb1a1
secretoglobin family 1A member 1
ISO
protein:decreased expression:serum
RGD
PMID:15467329
RGD:5144148
NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
G
Tbxa2r
thromboxane A2 receptor
treatment
ISO
RGD
PMID:22802632
RGD:11059529
NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Ccl2
C-C motif chemokine ligand 2
ISO
protein:increased expression:alveolar system (human)
RGD
PMID:11488333
RGD:11528564
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
G
Cxcl10
C-X-C motif chemokine ligand 10
ISO
protein:increased expression:respiratory system fluid/secretion
RGD
PMID:15956791
RGD:5135443
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
G
Cxcl9
C-X-C motif chemokine ligand 9
ISO
protein:increased expression:respiratory system fluid/secretion
RGD
PMID:15956791
RGD:5135443
NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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