RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: post-traumatic stress disorder
Accession: DOID:2055
browse the term
Definition: An anxiety disorder which results from a traumatic experience that results in psychological trauma. (DO)
Synonyms: exact_synonym: PTSD; acute post traumatic stress disorder; chronic post traumatic stress disorder; delayed onset post traumatic stress disorder; post-traumatic neuroses; posttraumatic neuroses; posttraumatic stress disorder; posttraumatic stress disorders; traumatic neurosis
primary_id: MESH:D013313
xref: EFO:0001358 ; ICD10CM:F43.1 ; ICD9CM:309.81 ; NCI:C3389
For additional species annotation, visit the
Alliance of Genome Resources .
G
Bax
BCL2 associated X, apoptosis regulator
IEP
RGD
PMID:23381833
RGD:10054113
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
G
Bcl2
BCL2, apoptosis regulator
IEP
RGD
PMID:23381833
RGD:10054113
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Bdnf
brain-derived neurotrophic factor
susceptibility treatment
ISO IEP
DNA:missense mutation:cds:196G>A (p.V66M) (human)
RGD
PMID:23319005 PMID:28791385
RGD:10059367 , RGD:401940159
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
G
Cacna1c
calcium voltage-gated channel subunit alpha1 C
ISO
ClinVar Annotator: match by term: Post-traumatic stress disorder
ClinVar
PMID:32332995
NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
G
Casp12
caspase 12
IEP
RGD
PMID:25331812
RGD:13782181
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
G
Casp9
caspase 9
IEP
RGD
PMID:25331812
RGD:13782181
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
G
Cnr1
cannabinoid receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:34262461
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
G
Cnr2
cannabinoid receptor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:34262461
NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
G
Fkbp5
FKBP prolyl isomerase 5
ISO
ClinVar Annotator: match by term: Post-traumatic stress disorder
ClinVar
PMID:18349090
NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
disease_progression
ISO
RGD
PMID:27421892
RGD:405255654
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
treatment
IEP
RGD
PMID:28791385
RGD:401940159
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
G
Hspa5
heat shock protein family A (Hsp70) member 5
IEP
RGD
PMID:25331812
RGD:13782181
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
G
Il2
interleukin 2
ISO
RGD
PMID:21714072
RGD:5147887
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
G
Mdm2
MDM2 proto-oncogene
IDA
RGD
PMID:23174211
RGD:10412309
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
IEP
mRNA, protein:altered expression:locus coeruleus (rat)
RGD
PMID:21584742
RGD:5686336
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
G
Ntrk2
neurotrophic receptor tyrosine kinase 2
IEP
protein:increased expression:hippocampus
RGD
PMID:20863519
RGD:5684783
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
G
Oprm1
opioid receptor, mu 1
severity
ISO
DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human)
RGD
PMID:22143634
RGD:401827931
NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
G
Pdia3
protein disulfide isomerase family A, member 3
IEP
RGD
PMID:25331812
RGD:13782181
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
G
Sigmar1
sigma non-opioid intracellular receptor 1
treatment
IMP
RGD
PMID:28791385
RGD:401940159
NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017
G
Wfs1
wolframin ER transmembrane glycoprotein
treatment
IEP
RGD
PMID:17968352
RGD:8694407
NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all