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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:acute stress disorder
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Accession:DOID:6088 term browser browse the term
Definition:Anxiety disorders manifested by the development of characteristic symptoms following a psychologically traumatic event that is outside the normal range of usual human experience. Symptoms include re-experiencing the traumatic event, increased arousal, and numbing of responsiveness to or reduced involvement with the external world. Traumatic stress disorders can be further classified by the time of onset and the duration of these symptoms.
Synonyms:exact_synonym: traumatic stress disorder;   traumatic stress disorders
 primary_id: MESH:D040921
 alt_id: RDO:0005245
 xref: ICD9CM:308.3
For additional species annotation, visit the Alliance of Genome Resources.


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acute stress disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase IEP RGD PMID:20645790 RGD:5509849 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28696432 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Crp C-reactive protein ISO RGD PMID:19628221 RGD:9585647 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
post-traumatic stress disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator IEP RGD PMID:23381833 RGD:10054113 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP RGD PMID:23381833 RGD:10054113 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor susceptibility ISO DNA:missense mutation:cds:196G>A (p.V66M) (human) RGD PMID:23319005 RGD:10059367 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Casp12 caspase 12 IEP RGD PMID:25331812 RGD:13782181 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp9 caspase 9 IEP RGD PMID:25331812 RGD:13782181 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 IEP RGD PMID:25331812 RGD:13782181 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Il2 interleukin 2 ISO RGD PMID:21714072 RGD:5147887 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Mdm2 MDM2 proto-oncogene IDA RGD PMID:23174211 RGD:10412309 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP mRNA, protein:altered expression:locus coeruleus (rat) RGD PMID:21584742 RGD:5686336 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IEP protein:increased expression:hippocampus RGD PMID:20863519 RGD:5684783 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 IEP RGD PMID:25331812 RGD:13782181 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein treatment IEP RGD PMID:17968352 RGD:8694407 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17129
    disease of anatomical entity 16476
      nervous system disease 12074
        central nervous system disease 10353
          brain disease 9712
            disease of mental health 7022
              Trauma and Stressor Related Disorders 19
                acute stress disorder 18
                  Acute Stress Disorders, Traumatic 0
                  Battered Child Syndrome 0
                  Psychological Trauma 0
                  combat disorder 0
                  post-traumatic stress disorder 12
Path 2
Term Annotations click to browse term
  disease 17129
    disease of anatomical entity 16476
      nervous system disease 12074
        central nervous system disease 10353
          brain disease 9712
            disease of mental health 7022
              cognitive disorder 1949
                anxiety disorder 166
                  acute stress disorder 18
                    Acute Stress Disorders, Traumatic 0
                    Battered Child Syndrome 0
                    Psychological Trauma 0
                    combat disorder 0
                    post-traumatic stress disorder 12
paths to the root