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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:penconazole
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Accession:CHEBI:81970 term browser browse the term
Definition:A racemate comprising equal amounts of (R)- and (S)-penconazole. A fungicide used to control powdery mildew, scab and other pathogenic Ascomycetes, Basidiomycetes and Deuteromycetes.
Synonyms:exact_synonym: rac-1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole
 related_synonym: (RS)-penconazole;   Formula=C13H15Cl2N3;   rac-penconazole;   racemic penconazole
 xref: CAS:66246-88-6;   KEGG:C18801
 xref_mesh: MESH:C087058
 xref: PMID:22878863;   PMID:23242260;   PMID:23811263;   PMID:23827731;   PMID:24431517;   PMID:24833021;   PMID:25171112;   PMID:25349889;   Pesticides:penconazole;   Reaxys:541488


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penconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha increases expression ISO penconazole results in increased expression of ACACA mRNA CTD PMID:31733957 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Sulfur co-treated with folpet co-treated with penconazole] affects the expression of BAX mRNA; [Sulfur co-treated with folpet co-treated with penconazole] results in increased expression of BAX mRNA CTD PMID:35564597 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO penconazole results in decreased expression of CCND1 mRNA CTD PMID:23811263 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A affects expression ISO penconazole affects the expression of CPT1A mRNA CTD PMID:31733957 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO penconazole results in decreased activity of CYP19A1 protein CTD PMID:37422065 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased expression of CYP3A4 mRNA CTD PMID:25028461 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity ISO penconazole results in decreased activity of CYP51A1 protein CTD PMID:16989930 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression ISO penconazole results in increased expression of DGAT1 mRNA CTD PMID:31733957 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Fasn fatty acid synthase increases expression ISO penconazole results in increased expression of FASN mRNA CTD PMID:31733957 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 increases expression ISO penconazole results in increased expression of G6PC1 mRNA CTD PMID:31733957 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Gck glucokinase increases expression ISO penconazole results in increased expression of GCK mRNA CTD PMID:31733957 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity ISO penconazole results in increased activity of GPT protein CTD PMID:31733957 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Il6 interleukin 6 increases expression ISO penconazole results in increased expression of IL6 mRNA CTD PMID:31733957 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 increases expression ISO penconazole results in increased expression of MOGAT1 mRNA CTD PMID:31733957 NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513 		JBrowse link
G Ncoa4 nuclear receptor coactivator 4 decreases expression ISO penconazole results in decreased expression of NCOA4 mRNA CTD PMID:23811263 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased activity of NR1I2 protein CTD PMID:25028461 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO penconazole results in decreased expression of PKLR mRNA CTD PMID:31733957 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO penconazole results in decreased expression of PPARA mRNA CTD PMID:31733957 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO penconazole results in increased expression of PPARG mRNA CTD PMID:31733957 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO penconazole results in increased expression of RXRA mRNA CTD PMID:23811263 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases activity ISO penconazole results in decreased activity of SLC22A8 protein CTD PMID:36669674 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression ISO penconazole results in increased expression of SLC2A2 mRNA CTD PMID:31733957 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO penconazole results in increased expression of SREBF1 mRNA CTD PMID:31733957 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Tcf7l1 transcription factor 7 like 1 increases expression ISO penconazole results in increased expression of TCF7L1 mRNA CTD PMID:23811263 NCBI chr 4:104,680,734...104,846,086
Ensembl chr 4:104,680,739...104,845,287 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO penconazole results in increased expression of TNF mRNA CTD PMID:31733957 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tpm3 tropomyosin 3 increases expression ISO penconazole results in increased expression of TPM3 mRNA CTD PMID:23811263 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein increases expression ISO penconazole results in increased expression of TPR mRNA CTD PMID:23811263 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      chemical substance 14383
        mixture 13700
          racemate 12076
            penconazole 27
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            organic molecule 19655
                              organic cyclic compound 19468
                                carbocyclic compound 18559
                                  benzenoid aromatic compound 17968
                                    benzenes 17830
                                      chlorobenzenes 14817
                                        dichlorobenzene 11519
                                          1-[2-(2,4-dichlorophenyl)pentyl]1,2,4-triazole 27
                                            (R)-penconazole 27
                                              penconazole 27
paths to the root