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diethyl hydrogen phosphate - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:diethyl hydrogen phosphate
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Accession:CHEBI:27708 term browser browse the term
Definition:A dialkyl phosphate having ethyl as the alkyl group.
Synonyms:related_synonym: Diethylphosphate;   Diethylphosphoric acid;   Formula=C4H11O4P;   InChI=1S/C4H11O4P/c1-3-7-9(5,6)8-4-2/h3-4H2,1-2H3,(H,5,6);   InChIKey=UCQFCFPECQILOL-UHFFFAOYSA-N;   O,O-Diethylphosphoric acid;   SMILES=CCOP(O)(=O)OCC
 alt_id: CHEBI:23712;   CHEBI:4529;   CHEBI:49570
 xref: CAS:598-02-7;   HMDB:HMDB0012209;   KEGG:C06608
 xref_mesh: MESH:C034789
 xref: PDBeChem:DPF;   PMID:17590257;   PMID:20494630;   PMID:22251442;   PMID:23522525;   Reaxys:1704113;   UM-BBD_compID:c0087
 cyclic_relationship: is_conjugate_acid_of CHEBI:140537


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diethyl hydrogen phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO
EXP
diethyl phosphate results in decreased expression of CYP11A1 mRNA
diethyl phosphate results in decreased expression of CYP11A1 mRNA; diethyl phosphate results in decreased expression of CYP11A1 protein
CTD PMID:35777568 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Dcx doublecortin multiple interactions ISO [diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of DCX mRNA CTD PMID:37914285 NCBI chr  X:112,227,455...112,370,291
Ensembl chr  X:107,430,767...107,507,476
JBrowse link
G Dio1 iodothyronine deiodinase 1 increases expression EXP diethyl phosphate results in increased expression of DIO1 mRNA CTD PMID:31835022 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dio2 iodothyronine deiodinase 2 increases expression EXP diethyl phosphate results in increased expression of DIO2 mRNA CTD PMID:31835022 NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dio3 iodothyronine deiodinase 3 increases expression EXP diethyl phosphate results in increased expression of DIO3 mRNA CTD PMID:31835022 NCBI chr 6:135,107,072...135,108,933
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G Gip gastric inhibitory polypeptide decreases secretion EXP diethyl phosphate results in decreased secretion of GIP protein CTD PMID:34038317 NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression EXP diethyl phosphate results in decreased expression of HSD11B1 mRNA CTD PMID:35777568 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Il6 interleukin 6 decreases secretion EXP diethyl phosphate results in decreased secretion of IL6 protein CTD PMID:34038317 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lep leptin decreases secretion EXP diethyl phosphate results in decreased secretion of LEP protein CTD PMID:34038317 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions ISO [diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of MAP2 mRNA CTD PMID:37914285 NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects binding ISO diethyl phosphate binds to NR3C1 protein CTD PMID:35777568 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression ISO
EXP
diethyl phosphate results in increased expression of NR4A1 mRNA; diethyl phosphate results in increased expression of NR4A1 protein CTD PMID:35777568 NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 increases expression EXP diethyl phosphate results in increased expression of NR5A1 mRNA CTD PMID:35777568 NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:22,465,502...22,486,328
JBrowse link
G Pax6 paired box 6 multiple interactions ISO [diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of PAX6 mRNA CTD PMID:37914285 NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Pomc proopiomelanocortin decreases secretion
multiple interactions
increases expression
ISO
EXP
diethyl phosphate results in decreased secretion of POMC protein
Colforsin inhibits the reaction [diethyl phosphate results in decreased secretion of POMC protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [diethyl phosphate results in decreased secretion of POMC protein]; U 0126 inhibits the reaction [diethyl phosphate results in decreased secretion of POMC protein]
diethyl phosphate results in decreased expression of and results in decreased secretion of POMC protein
diethyl phosphate results in increased expression of POMC mRNA
CTD PMID:35777568 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Rbfox3 RNA binding fox-1 homolog 3 multiple interactions ISO [diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of RBFOX3 mRNA CTD PMID:37914285 NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression EXP diethyl phosphate results in decreased expression of SCARB1 mRNA CTD PMID:35777568 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP diethyl phosphate results in increased expression of SERPINA7 mRNA CTD PMID:31835022 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Slc16a10 solute carrier family 16 member 10 decreases expression EXP diethyl phosphate results in decreased expression of SLC16A10 mRNA CTD PMID:31835022 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
JBrowse link
G Slc22a6 solute carrier family 22 member 6 decreases expression EXP diethyl phosphate results in decreased expression of SLC22A6 mRNA CTD PMID:31835022 NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP
ISO
diethyl phosphate results in decreased expression of STAR mRNA CTD PMID:35777568 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 decreases expression EXP diethyl phosphate results in decreased expression of SULT1B1 mRNA CTD PMID:31835022 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483
JBrowse link
G Thra thyroid hormone receptor alpha increases expression EXP diethyl phosphate results in increased expression of THRA mRNA CTD PMID:31835022 NCBI chr10:84,198,141...84,225,659
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Thrb thyroid hormone receptor beta increases expression EXP diethyl phosphate results in increased expression of THRB mRNA CTD PMID:31835022 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Tshb thyroid stimulating hormone subunit beta decreases expression EXP diethyl phosphate results in decreased expression of TSHB protein CTD PMID:31835022 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link

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  CHEBI ontology 20856
    role 20816
      biological role 20814
        biochemical role 20261
          metabolite 20243
            xenobiotic metabolite 16611
              human xenobiotic metabolite 16294
                diethyl hydrogen phosphate 25
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  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    p-block element atom 20777
                      chalcogen 20489
                        oxygen atom 20455
                          oxygen molecular entity 20455
                            hydroxides 20228
                              oxoacid 19285
                                pnictogen oxoacid 15114
                                  phosphorus oxoacid 14668
                                    phosphoric acids 13988
                                      phosphoric acid 13988
                                        phosphoric acid derivative 13899
                                          phosphate 13898
                                            organic phosphate 13898
                                              alkyl phosphate 7989
                                                dialkyl phosphate 7521
                                                  diethyl hydrogen phosphate 25
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