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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to tumor necrosis factor
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Accession:GO:0071356 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
Synonyms:exact_synonym: cellular response to TNF


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cellular response to tumor necrosis factor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO RGD PMID:20300455 RGD:39456124 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 ISO RGD PMID:20702406 RGD:11081005 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ACOD1 aconitate decarboxylase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G ACTR3 actin related protein 3 ISO RGD PMID:22319661 RGD:11530045 NCBI chr 2:113,889,934...113,962,596
Ensembl chr 2:113,890,063...113,962,596 		JBrowse link
G ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif 12 involved_in IMP (PMID:18485748) BHF-UCL PMID:18485748 NCBI chr 5:33,523,535...33,891,990
Ensembl chr 5:33,523,535...33,892,019 		JBrowse link
G ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 involved_in ISO
IEA		 RGD
Ensembl		 PMID:18433458 GO_REF:0000107 RGD:2315954 NCBI chr 9:133,414,337...133,459,386
Ensembl chr 9:133,414,358...133,459,402 		JBrowse link
G ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif 7 involved_in IMP (PMID:18485748) BHF-UCL PMID:18485748 NCBI chr15:78,759,206...78,811,464
Ensembl chr15:78,759,206...78,811,464 		JBrowse link
G ADGRE1 adhesion G protein-coupled receptor E1 ISO RGD PMID:23110133 RGD:151665477 NCBI chr19:6,887,579...6,940,450
Ensembl chr19:6,887,566...6,940,459 		JBrowse link
G AKAP12 A-kinase anchoring protein 12 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20454828 GO_REF:0000107 RGD:14348957 NCBI chr 6:151,239,967...151,358,559
Ensembl chr 6:151,239,967...151,358,559 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24349514) Ensembl
MGI		 PMID:24349514 GO_REF:0000107 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ANKRD1 ankyrin repeat domain 1 involved_in IDA (PMID:7730328) BHF-UCL PMID:7730328 NCBI chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087 		JBrowse link
G APOB apolipoprotein B ISO RGD PMID:17405916 RGD:2325768 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:155,946,854...155,979,617
Ensembl chr 1:155,946,851...156,007,070 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:18,055,992...18,084,961
Ensembl chr 8:18,055,992...18,084,998 		JBrowse link
G ASL argininosuccinate lyase ISO with interferon-gamma RGD PMID:11072090 RGD:4139899 NCBI chr 7:66,075,819...66,093,576
Ensembl chr 7:66,075,800...66,094,697 		JBrowse link
G ASS1 argininosuccinate synthase 1 involved_in ISO
IEA		 with interferon-gamma
TNFalpha		 RGD
Ensembl		 PMID:11072090 PMID:12589771 GO_REF:0000107 RGD:1599307 RGD:4139899 NCBI chr 9:130,444,707...130,501,274
Ensembl chr 9:130,444,961...130,501,274 		JBrowse link
G BAG4 BAG cochaperone 4 involved_in IDA (PMID:21712384) UniProt PMID:21712384 NCBI chr 8:38,176,855...38,213,301
Ensembl chr 8:38,176,533...38,213,301 		JBrowse link
G BCL2L1 BCL2 like 1 ISO RGD PMID:21937453 RGD:11353803 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BDNF brain derived neurotrophic factor ISO RGD PMID:21958434 RGD:8657122 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18621737) Ensembl
MGI		 PMID:18621737 GO_REF:0000107 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 acts_upstream_of_or_within ISO (PMID:18621737) MGI PMID:18621737 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in IMP (PMID:23415688) BHF-UCL PMID:23415688 NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245 		JBrowse link
G CACTIN cactin, spliceosome C complex subunit involved_in IDA (PMID:20829348) UniProt PMID:20829348 NCBI chr19:3,610,645...3,626,790
Ensembl chr19:3,610,645...3,626,815 		JBrowse link
G CALCA calcitonin related polypeptide alpha involved_in ISO
IEA		 RGD
Ensembl		 PMID:21958434 GO_REF:0000107 RGD:8657122 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CALCR calcitonin receptor ISO RGD PMID:23110133 RGD:151665477 NCBI chr 7:93,424,486...93,574,724
Ensembl chr 7:93,424,486...93,574,730 		JBrowse link
G CAMP cathelicidin antimicrobial peptide involved_in ISO
IEA		 TNFalpha RGD
Ensembl		 PMID:19879657 GO_REF:0000107 RGD:2316237 NCBI chr 3:48,223,495...48,225,485
Ensembl chr 3:48,223,347...48,225,491 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 involved_in ISO
ISS
IEP		 (PMID:9407497) RGD
BHF-UCL
UniProt		 PMID:9407497 PMID:14512159 GO_REF:0000024 RGD:8548859 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 involved_in IEP (PMID:9407497) UniProt PMID:9407497 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 involved_in ISO
IEP		 (PMID:9407497) RGD
UniProt		 PMID:9407497 PMID:20663893 RGD:4889885 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCN1 cellular communication network factor 1 ISO RGD PMID:15117851 RGD:329845570 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO RGD PMID:23110133 RGD:151665477 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO RGD PMID:23110133 RGD:151665477 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CD40 CD40 molecule involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:10403401 GO_REF:0000107 GO_REF:0000118 RGD:634252 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:26095681 RGD:11344966 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CD58 CD58 molecule involved_in IDA (PMID:19109405) UniProt PMID:19109405 NCBI chr 1:116,514,534...116,571,026
Ensembl chr 1:116,514,534...116,571,039 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1618860) Ensembl
MGI		 PMID:1618860 GO_REF:0000107 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:24760020 RGD:11570414 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026 		JBrowse link
G CHI3L1 chitinase 3 like 1 involved_in ISO
ISS		 TNF-alpha RGD
UniProt		 PMID:16234240 GO_REF:0000024 RGD:4892601 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex involved_in IDA (PMID:23091055) UniProt PMID:23091055 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CIB1 calcium and integrin binding 1 involved_in IMP (PMID:19854831) UniProt PMID:19854831 NCBI chr15:90,229,975...90,265,759
Ensembl chr15:90,229,975...90,234,047 		JBrowse link
G CLDN1 claudin 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:21748286 GO_REF:0000107 RGD:11341809 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446 		JBrowse link
G COL1A1 collagen type I alpha 1 chain involved_in ISO
IEA		 RGD
Ensembl		 PMID:17485223 GO_REF:0000107 RGD:8552773 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL2A1 collagen type II alpha 1 chain ISO RGD PMID:19144181 RGD:8661243 NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554 		JBrowse link
G CRHBP corticotropin releasing hormone binding protein involved_in IDA (PMID:15345745) UniProt PMID:15345745 NCBI chr 5:76,953,045...76,981,159
Ensembl chr 5:76,953,045...76,981,158 		JBrowse link
G CRIPTO cripto, EGF-CFC family member involved_in IDA (PMID:17720976) UniProt PMID:17720976 NCBI chr 3:46,574,535...46,582,457
Ensembl chr 3:46,574,534...46,582,457 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:23110133 RGD:151665477 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G CTSK cathepsin K involved_in ISO
IEA		 RGD
Ensembl		 PMID:23110133 GO_REF:0000107 RGD:151665477 NCBI chr 1:150,796,208...150,808,260
Ensembl chr 1:150,794,880...150,809,577 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 involved_in ISO PMID:12729461 ARUK-UCL PMID:12729461 RGD:13673777 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 involved_in IEP (PMID:9407497) UniProt PMID:9407497 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYBA cytochrome b-245 alpha chain ISO RGD PMID:9445395 RGD:2317868 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO RGD PMID:9397943 RGD:4891988 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 involved_in ISO
IEA		 TNF-alpha RGD
Ensembl		 PMID:10403529 GO_REF:0000107 RGD:7815048 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IDA
IEA		 (PMID:12813029), (PMID:15310755), (PMID:17389591) BHF-UCL
Ensembl		 PMID:12813029 PMID:15310755 PMID:17389591 GO_REF:0000107 NCBI chr 9:121,567,074...121,785,530
Ensembl chr 9:121,567,057...121,785,530 		JBrowse link
G DAXX death domain associated protein ISO RGD PMID:21572393 RGD:9587767 NCBI chr 6:33,318,558...33,322,959
Ensembl chr 6:33,318,558...33,323,016 		JBrowse link
G DBN1 drebrin 1 ISO RGD PMID:22319661 RGD:11530045 NCBI chr 5:177,456,610...177,473,634
Ensembl chr 5:177,456,608...177,474,401 		JBrowse link
G DCSTAMP dendrocyte expressed seven transmembrane protein involved_in ISS
IEA
ISO		 UniProt
Ensembl
RGD		 PMID:23110133 GO_REF:0000024 GO_REF:0000107 RGD:151665477 NCBI chr 8:104,339,796...104,356,689
Ensembl chr 8:104,339,087...104,356,689 		JBrowse link
G DHX9 DExH-box helicase 9 involved_in IMP (PMID:15355351) UniProt PMID:15355351 NCBI chr 1:182,839,347...182,887,982
Ensembl chr 1:182,839,347...182,887,982 		JBrowse link
G DICER1 dicer 1, ribonuclease III ISO RGD PMID:23239824 RGD:149735901 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G EDN1 endothelin 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20512083 GO_REF:0000107 RGD:4144864 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:23990338 RGD:9685490 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 ISO RGD PMID:23990338 RGD:9685490 NCBI chr 9:137,048,107...137,054,061
Ensembl chr 9:137,048,107...137,054,061 		JBrowse link
G ERBIN erbb2 interacting protein involved_in IMP (PMID:16203728) UniProt PMID:16203728 NCBI chr 5:65,926,575...66,082,546
Ensembl chr 5:65,883,128...66,082,546 		JBrowse link
G FABP4 fatty acid binding protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1618860) Ensembl
MGI		 PMID:1618860 GO_REF:0000107 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236 		JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:10678925 RGD:8662912 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FCAR Fc alpha receptor involved_in IDA (PMID:25339672) CAFA PMID:25339672 NCBI chr19:54,874,235...54,891,420
Ensembl chr19:54,874,235...54,891,420 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit involved_in ISO
IEA		 RGD
Ensembl		 PMID:23110133 GO_REF:0000107 RGD:151665477 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOXP1 forkhead box P1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:26842647 GO_REF:0000107 RGD:11561903 NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,693...71,583,978 		JBrowse link
G GATA3 GATA binding protein 3 involved_in IEP (PMID:19674970) UniProt PMID:19674970 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IMP (PMID:19279008) BHF-UCL PMID:19279008 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G GBP1 guanylate binding protein 1 involved_in IEP (PMID:17266443) UniProt PMID:17266443 NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,051,882...89,065,360 		JBrowse link
G GBP2 guanylate binding protein 2 involved_in IEP (PMID:17266443) UniProt PMID:17266443 NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456 		JBrowse link
G GBP3 guanylate binding protein 3 involved_in IEP (PMID:17266443) UniProt PMID:17266443 NCBI chr 1:89,006,680...89,022,866
Ensembl chr 1:89,006,679...89,022,894 		JBrowse link
G GBP4 guanylate binding protein 4 involved_in ISO (MGI:4412460|PMID:18025219) UniProt PMID:18025219 MGI:4412460 NCBI chr 1:89,181,144...89,198,942
Ensembl chr 1:89,181,144...89,198,942 		JBrowse link
G GFER growth factor, augmenter of liver regeneration involved_in ISO
IEA		 RGD
Ensembl		 PMID:23073658 GO_REF:0000107 RGD:9685733 NCBI chr16:1,984,193...1,987,749
Ensembl chr16:1,984,193...1,987,749 		JBrowse link
G GPD1 glycerol-3-phosphate dehydrogenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:3027100) Ensembl
MGI		 PMID:3027100 GO_REF:0000107 NCBI chr12:50,104,008...50,111,313
Ensembl chr12:50,103,982...50,111,313 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in IDA (PMID:23285008) UniProt PMID:23285008 NCBI chr 7:1,087,118...1,093,810
Ensembl chr 7:1,082,208...1,093,815 		JBrowse link
G GSDME gasdermin E involved_in IDA (PMID:28459430) UniProt PMID:28459430 NCBI chr 7:24,698,355...24,795,539
Ensembl chr 7:24,698,355...24,757,940 		JBrowse link
G HAMP hepcidin antimicrobial peptide ISO RGD PMID:23506423 RGD:11041627 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143 		JBrowse link
G HAS2 hyaluronan synthase 2 involved_in IEP (PMID:20522558) BHF-UCL PMID:20522558 NCBI chr 8:121,612,116...121,641,440
Ensembl chr 8:121,612,116...121,641,440 		JBrowse link
G HDAC1 histone deacetylase 1 ISO RGD PMID:20037577 RGD:9590131 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:22389387 RGD:9681445 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:23589286 GO_REF:0000107 RGD:9685382 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G HMHB1 histocompatibility minor HB-1 involved_in IDA (PMID:8992968) UniProt PMID:8992968 NCBI chr 5:143,812,161...143,820,716
Ensembl chr 5:143,812,161...143,820,716 		JBrowse link
G HYAL1 hyaluronidase 1 involved_in IEP (PMID:18390475) UniProt PMID:18390475 NCBI chr 3:50,299,893...50,312,381
Ensembl chr 3:50,299,890...50,312,381 		JBrowse link
G HYAL2 hyaluronidase 2 involved_in IEP (PMID:18390475) UniProt PMID:18390475 NCBI chr 3:50,317,808...50,322,745
Ensembl chr 3:50,317,790...50,322,782 		JBrowse link
G HYAL3 hyaluronidase 3 involved_in IEP (PMID:18390475) UniProt PMID:18390475 NCBI chr 3:50,292,832...50,299,405
Ensembl chr 3:50,292,831...50,299,405 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:15087287 RGD:1358663 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in IDA (PMID:23091055) UniProt PMID:23091055 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL18 interleukin 18 ISO RGD PMID:18547159 RGD:4889457 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL18BP interleukin 18 binding protein involved_in ISO
IEA		 RGD
Ensembl		 PMID:12684057 GO_REF:0000107 RGD:4889505 NCBI chr11:71,998,909...72,008,200
Ensembl chr11:71,998,613...72,007,315 		JBrowse link
G IL6 interleukin 6 acts_upstream_of_or_within ISO (PMID:19955433) RGD
MGI		 PMID:2121800 PMID:19955433 RGD:7829782 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in IDA (PMID:21712384) UniProt PMID:21712384 NCBI chr17:1,494,577...1,516,612
Ensembl chr17:1,494,577...1,516,742 		JBrowse link
G IRF1 interferon regulatory factor 1 ISO RGD PMID:16978650 RGD:5128784 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719 		JBrowse link
G KAT2A lysine acetyltransferase 2A involved_in ISO
IEA		 RGD
Ensembl		 PMID:20130956 GO_REF:0000107 RGD:9590236 NCBI chr17:42,113,111...42,121,367
Ensembl chr17:42,113,111...42,121,367 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 involved_in ISO
IEA		 RGD
Ensembl		 PMID:19460779 GO_REF:0000107 RGD:7296986 NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331 		JBrowse link
G KLF2 KLF transcription factor 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:18406357 GO_REF:0000107 RGD:2316543 NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685 		JBrowse link
G LCN2 lipocalin 2 ISO TNFalpha RGD PMID:19329498 PMID:22249220 RGD:126781756 RGD:2316495 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20716917 GO_REF:0000107 RGD:10412640 NCBI chr 6:136,557,046...136,793,091
Ensembl chr 6:136,557,046...136,793,097 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20659889 GO_REF:0000107 RGD:155804281 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24349514) Ensembl
MGI		 PMID:24349514 GO_REF:0000107 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24349514) Ensembl
MGI		 PMID:24349514 GO_REF:0000107 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24349514) Ensembl
MGI		 PMID:24349514 GO_REF:0000107 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO TNFalpha RGD PMID:9475517 RGD:2304245 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MIR101-2 microRNA 101-2 acts_upstream_of_or_within ISO (PMID:24349514) MGI PMID:24349514 NCBI chr 9:4,850,297...4,850,375
Ensembl chr 9:4,850,297...4,850,375 		JBrowse link
G MIR103A1 microRNA 103a-1 acts_upstream_of_or_within ISO (PMID:19188425) MGI PMID:19188425 NCBI chr 5:168,560,896...168,560,973
Ensembl chr 5:168,560,896...168,560,973 		JBrowse link
G MIR103A2 microRNA 103a-2 acts_upstream_of_or_within ISO (PMID:19188425) MGI PMID:19188425 NCBI chr20:3,917,494...3,917,571
Ensembl chr20:3,917,494...3,917,571 		JBrowse link
G MIR125B1 microRNA 125b-1 acts_upstream_of_or_within ISO (PMID:19188425) MGI PMID:19188425 NCBI chr11:122,099,757...122,099,844
Ensembl chr11:122,099,757...122,099,844 		JBrowse link
G MIR125B2 microRNA 125b-2 acts_upstream_of_or_within ISO (PMID:19188425) MGI PMID:19188425 NCBI chr21:16,590,237...16,590,325
Ensembl chr21:16,590,237...16,590,325 		JBrowse link
G MIR143 microRNA 143 acts_upstream_of_or_within ISO (PMID:19188425) MGI PMID:19188425 NCBI chr 5:149,428,918...149,429,023
Ensembl chr 5:149,428,918...149,429,023 		JBrowse link
G MIR146B microRNA 146b acts_upstream_of_or_within ISO (PMID:19188425) MGI PMID:19188425 NCBI chr10:102,436,512...102,436,584
Ensembl chr10:102,436,512...102,436,584 		JBrowse link
G MIR148A microRNA 148a acts_upstream_of_or_within ISO (PMID:19188425) MGI PMID:19188425 NCBI chr 7:25,949,919...25,949,986
Ensembl chr 7:25,949,919...25,949,986 		JBrowse link
G MIR181B1 microRNA 181b-1 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 1:198,858,873...198,858,982
Ensembl chr 1:198,858,873...198,858,982 		JBrowse link
G MIR181B2 microRNA 181b-2 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 9:124,693,710...124,693,798
Ensembl chr 9:124,693,710...124,693,798 		JBrowse link
G MIR20B microRNA 20b involved_in IDA (PMID:28595801) BHF-UCL PMID:28595801 NCBI chr  X:134,169,809...134,169,877
Ensembl chr  X:134,169,809...134,169,877 		JBrowse link
G MIR221 microRNA 221 acts_upstream_of_or_within ISO (PMID:19188425) MGI PMID:19188425 NCBI chr  X:45,746,157...45,746,266
Ensembl chr  X:45,746,157...45,746,266 		JBrowse link
G MIR222 microRNA 222 acts_upstream_of_or_within ISO (PMID:19188425) MGI PMID:19188425 NCBI chr  X:45,747,015...45,747,124
Ensembl chr  X:45,747,015...45,747,124 		JBrowse link
G MIR27A microRNA 27a ISO RGD PMID:29373037 RGD:26923905 NCBI chr19:13,836,440...13,836,517
Ensembl chr19:13,836,440...13,836,517 		JBrowse link
G MIR28 microRNA 28 ISO RGD PMID:29373037 RGD:26923905 NCBI chr 3:188,688,781...188,688,866
Ensembl chr 3:188,688,781...188,688,866 		JBrowse link
G MIR30C2 microRNA 30c-2 involved_in IDA (PMID:25732226) ARUK-UCL PMID:25732226 NCBI chr 6:71,376,960...71,377,031
Ensembl chr 6:71,376,960...71,377,031 		JBrowse link
G MIR31 microRNA 31 involved_in IDA (PMID:19949084) BHF-UCL PMID:19949084 NCBI chr 9:21,512,115...21,512,185
Ensembl chr 9:21,512,115...21,512,185 		JBrowse link
G MIR331 microRNA 331 acts_upstream_of_or_within ISO (PMID:24349514) MGI PMID:24349514 NCBI chr12:95,308,420...95,308,513
Ensembl chr12:95,308,420...95,308,513 		JBrowse link
G MIR34A microRNA 34a ISO RGD PMID:29373037 RGD:26923905 NCBI chr 1:9,151,668...9,151,777
Ensembl chr 1:9,151,668...9,151,777 		JBrowse link
G MIR378A microRNA 378a acts_upstream_of_or_within ISO (PMID:19188425) MGI PMID:19188425 NCBI chr 5:149,732,825...149,732,890
Ensembl chr 5:149,732,825...149,732,890 		JBrowse link
G MIR494 microRNA 494 acts_upstream_of_or_within ISO (PMID:24349514) MGI PMID:24349514 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714 		JBrowse link
G MIR766 microRNA 766 involved_in IDA (PMID:30769772) ARUK-UCL PMID:30769772 NCBI chr  X:119,646,738...119,646,848
Ensembl chr  X:119,646,738...119,646,848 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:22410640 RGD:7207278 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:22410640 RGD:7207278 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MUC19 mucin 19, oligomeric ISO RGD PMID:19533339 RGD:11554183 (All species) (All species) NCBI chr12:40,393,394...40,570,757
Ensembl chr12:40,393,395...40,570,832 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming ISO RGD PMID:15492162 PMID:18507686 RGD:11554332 RGD:2324885 (All species) (All species) NCBI chr11:1,074,874...1,110,508
Ensembl chr11:1,074,875...1,110,511 		JBrowse link
G MYOD1 myogenic differentiation 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24349514) Ensembl
MGI		 PMID:24349514 GO_REF:0000107 NCBI chr11:17,719,571...17,722,136
Ensembl chr11:17,719,571...17,722,136 		JBrowse link
G MYOG myogenin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24349514) Ensembl
MGI		 PMID:24349514 GO_REF:0000107 NCBI chr 1:203,083,129...203,086,012
Ensembl chr 1:203,083,129...203,086,012 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:23110133 GO_REF:0000107 RGD:151665477 NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in ISO
IEA
IMP		 (PMID:18202225) RGD
Ensembl
BHF-UCL		 PMID:18202225 PMID:29373037 GO_REF:0000107 RGD:26923905 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:24349514) RGD
Ensembl
MGI		 PMID:9718198 PMID:18625500 PMID:24349514 GO_REF:0000107 RGD:10045657 RGD:10045871 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:24349514) Ensembl
MGI
GO_Central		 PMID:24349514 GO_REF:0000033 GO_REF:0000107 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NFKBIE NFKB inhibitor epsilon involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:44,258,166...44,265,551
Ensembl chr 6:44,258,166...44,265,788 		JBrowse link
G NKX3-1 NK3 homeobox 1 involved_in IEP (PMID:18757402) UniProt PMID:18757402 NCBI chr 8:23,678,693...23,682,938
Ensembl chr 8:23,678,697...23,682,938 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO with IL1beta RGD PMID:21965676 RGD:5508742 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO RGD PMID:22566503 RGD:7794760 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NPNT nephronectin involved_in ISS
IEA		 (PMID:15754038) BHF-UCL
Ensembl		 PMID:15754038 GO_REF:0000107 NCBI chr 4:105,895,471...105,971,671
Ensembl chr 4:105,894,775...106,004,027 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:40,092,793...40,100,589
Ensembl chr17:40,092,793...40,100,589 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO RGD PMID:21958434 RGD:8657122 NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751 		JBrowse link
G OCLN occludin ISO RGD PMID:21748286 RGD:11341809 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104 		JBrowse link
G OCSTAMP osteoclast stimulatory transmembrane protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:46,540,946...46,550,654
Ensembl chr20:46,540,946...46,550,654 		JBrowse link
G OPTN optineurin ISO RGD PMID:28776281 RGD:13432574 NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,138,308 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:18335579 GO_REF:0000107 RGD:10445832 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial involved_in ISO
IEA		 RGD
Ensembl		 PMID:19268478 GO_REF:0000107 RGD:10427879 NCBI chr14:24,094,171...24,104,125
Ensembl chr14:24,094,053...24,110,598 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IEA
NAS
ISS		 (PMID:20140872) Ensembl
BHF-UCL		 PMID:20140872 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:229,023,973...229,271,287
Ensembl chr 2:228,850,526...229,271,287 		JBrowse link
G POSTN periostin involved_in ISO
IEA		 RGD
Ensembl		 PMID:20458732 GO_REF:0000107 RGD:10041020 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22343369 RGD:7242186 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PRPF8 pre-mRNA processing factor 8 involved_in ISO
IEA		 RGD
Ensembl		 PMID:1345341 GO_REF:0000107 RGD:10045884 NCBI chr17:1,650,629...1,684,867
Ensembl chr17:1,650,629...1,684,867 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO and macrophage migration inhibitory factor RGD PMID:14629650 RGD:401959403 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IDA (PMID:12486103) UniProt PMID:12486103 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G REG3A regenerating family member 3 alpha ISO RGD PMID:10982776 RGD:9831402 NCBI chr 2:79,157,006...79,159,753
Ensembl chr 2:79,157,003...79,159,753 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IDA
IMP
IEA
ISO		 (PMID:18073330), (PMID:23091055)
(PMID:18045535)		 UniProt
CAFA
Ensembl
RGD		 PMID:15980038 PMID:18045535 PMID:18073330 PMID:23091055 GO_REF:0000107 RGD:152025214 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in IDA (PMID:17389591) UniProt PMID:17389591 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G RORA RAR related orphan receptor A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19955433) Ensembl
MGI		 PMID:19955433 GO_REF:0000107 NCBI chr15:60,488,284...61,229,302
Ensembl chr15:60,488,284...61,229,302 		JBrowse link
G RPS3 ribosomal protein S3 involved_in IMP (PMID:18045535) CAFA PMID:18045535 NCBI chr11:75,399,518...75,422,302
Ensembl chr11:75,399,515...75,422,280 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IDA (PMID:9391078) UniProt PMID:9391078 NCBI chr 8:41,261,962...41,309,473
Ensembl chr 8:41,261,962...41,309,473 		JBrowse link
G SGMS1 sphingomyelin synthase 1 ISO RGD PMID:12353928 RGD:1302423 NCBI chr10:50,305,600...50,625,184
Ensembl chr10:50,305,586...50,625,163 		JBrowse link
G SIRT1 sirtuin 1 involved_in IDA (PMID:15152190) UniProt PMID:15152190 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO RGD PMID:16221503 RGD:5688725 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1618860) Ensembl
MGI		 PMID:1618860 GO_REF:0000107 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G SLK STE20 like kinase ISO RGD PMID:21572393 RGD:9587767 NCBI chr10:103,967,140...104,029,233
Ensembl chr10:103,967,140...104,029,233 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16025116), (PMID:20352118) Ensembl
MGI		 PMID:16025116 PMID:20352118 GO_REF:0000107 NCBI chr16:68,358,327...68,448,508
Ensembl chr16:68,358,327...68,448,508 		JBrowse link
G SMPD4 sphingomyelin phosphodiesterase 4 involved_in IDA
IEA		 (PMID:16517606) BHF-UCL
Ensembl		 PMID:16517606 GO_REF:0000107 NCBI chr 2:130,151,392...130,181,757
Ensembl chr 2:130,151,392...130,182,750 		JBrowse link
G SNRNP70 small nuclear ribonucleoprotein U1 subunit 70 ISO RGD PMID:10022522 RGD:10448942 NCBI chr19:49,085,451...49,108,604
Ensembl chr19:49,085,419...49,108,605 		JBrowse link
G TANK TRAF family member associated NFKB activator involved_in IMP (PMID:25861989) UniProt PMID:25861989 NCBI chr 2:161,136,963...161,236,230
Ensembl chr 2:161,136,908...161,236,230 		JBrowse link
G THBS1 thrombospondin 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:15831915 GO_REF:0000107 RGD:2317962 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B involved_in ISO
IEA		 RGD
Ensembl		 PMID:11324713 GO_REF:0000107 RGD:13825430 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TNFRSF21 TNF receptor superfamily member 21 involved_in IDA (PMID:19654028) UniProt PMID:19654028 NCBI chr 6:47,231,532...47,309,905
Ensembl chr 6:47,231,532...47,309,905 		JBrowse link
G TRADD TNFRSF1A associated via death domain involved_in IMP (PMID:25732226) ARUK-UCL PMID:25732226 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,154,185...67,159,909 		JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:21958434 GO_REF:0000107 RGD:8657122 NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 involved_in IEA
ISO		 Ensembl
RGD		 PMID:15980038 PMID:23035855 GO_REF:0000107 RGD:152025214 RGD:7207794 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G WDR35 WD repeat domain 35 ISO RGD PMID:20193664 RGD:11553917 NCBI chr 2:19,910,263...19,990,105
Ensembl chr 2:19,910,263...19,990,105 		JBrowse link
G XDH xanthine dehydrogenase ISO RGD PMID:12653206 RGD:1624380 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
G YBX3 Y-box binding protein 3 involved_in IMP (PMID:22711822) BHF-UCL PMID:22711822 NCBI chr12:10,699,089...10,723,323
Ensembl chr12:10,699,089...10,723,323 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IDA (PMID:19909337) UniProt PMID:19909337 NCBI chr 1:37,474,580...37,484,377
Ensembl chr 1:37,474,580...37,484,377 		JBrowse link
G ZFAND6 zinc finger AN1-type containing 6 involved_in IMP (PMID:21810480) UniProt PMID:21810480 NCBI chr15:80,058,951...80,138,393
Ensembl chr15:80,059,568...80,138,393 		JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in IEA
IDA		 (PMID:20166898) Ensembl
UniProt		 PMID:20166898 GO_REF:0000107 NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,407 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in IDA (PMID:20166898) UniProt PMID:20166898 NCBI chr14:68,787,655...68,796,243
Ensembl chr14:68,787,660...68,796,253 		JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in IDA (PMID:20166898) UniProt PMID:20166898 NCBI chr 2:43,222,402...43,226,606
Ensembl chr 2:43,222,402...43,226,606 		JBrowse link
G ZNF268 zinc finger protein 268 involved_in IDA (PMID:23091055) UniProt PMID:23091055 NCBI chr12:133,181,495...133,214,832
Ensembl chr12:133,181,409...133,214,832 		JBrowse link
negative regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in IDA (PMID:10604883) BHF-UCL PMID:10604883 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G APOA1 apolipoprotein A1 involved_in IDA (PMID:21571275) BHF-UCL PMID:21571275 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 involved_in IDA (PMID:11865055) UniProt PMID:11865055 NCBI chr20:63,235,905...63,240,495
Ensembl chr20:63,235,883...63,240,495 		JBrowse link
G CARD16 caspase recruitment domain family member 16 involved_in IMP (PMID:16920334) UniProt PMID:16920334 NCBI chr11:105,041,563...105,045,335
Ensembl chr11:105,041,326...105,101,431 		JBrowse link
G CARD8 caspase recruitment domain family member 8 involved_in IMP (PMID:11821383) UniProt PMID:11821383 NCBI chr19:48,179,825...48,255,946
Ensembl chr19:48,180,770...48,255,946 		JBrowse link
G CCDC3 coiled-coil domain containing 3 involved_in IMP (PMID:25193116) UniProt PMID:25193116 NCBI chr10:12,896,625...13,099,989
Ensembl chr10:12,896,625...13,099,652 		JBrowse link
G CLDN18 claudin 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22437732) Ensembl
MGI		 PMID:22437732 GO_REF:0000107 NCBI chr 3:137,998,816...138,033,649
Ensembl chr 3:137,998,735...138,033,655 		JBrowse link
G DICER1 dicer 1, ribonuclease III acts_upstream_of IDA (PMID:26435691) ARUK-UCL PMID:26435691 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IDA (PMID:19781631) UniProt PMID:19781631 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G GAS6 growth arrest specific 6 involved_in IDA (PMID:19657094) UniProt PMID:19657094 NCBI chr13:113,820,549...113,864,076
Ensembl chr13:113,820,549...113,864,076 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:7,312,661...7,315,360
Ensembl chr17:7,311,324...7,315,564 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in IC (PMID:16636664) BHF-UCL PMID:16636664 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G H2BC11 H2B clustered histone 11 involved_in IDA (PMID:11859126) UniProt PMID:11859126 NCBI chr 6:27,132,316...27,132,795
Ensembl chr 6:27,125,897...27,132,795 		JBrowse link
G MIR125B1 microRNA 125b-1 acts_upstream_of IDA (PMID:26435691) ARUK-UCL PMID:26435691 NCBI chr11:122,099,757...122,099,844
Ensembl chr11:122,099,757...122,099,844 		JBrowse link
G MIR125B2 microRNA 125b-2 acts_upstream_of IDA (PMID:26435691) ARUK-UCL PMID:26435691 NCBI chr21:16,590,237...16,590,325
Ensembl chr21:16,590,237...16,590,325 		JBrowse link
G MIR130A microRNA 130a acts_upstream_of IDA (PMID:26435691) ARUK-UCL PMID:26435691 NCBI chr11:57,641,198...57,641,286
Ensembl chr11:57,641,198...57,641,286 		JBrowse link
G MIR152 microRNA 152 involved_in IDA (PMID:24813629) BHF-UCL PMID:24813629 NCBI chr17:48,037,161...48,037,247
Ensembl chr17:48,037,161...48,037,247 		JBrowse link
G MIR24-1 microRNA 24-1 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 9:95,086,021...95,086,088
Ensembl chr 9:95,086,021...95,086,088 		JBrowse link
G MIR24-2 microRNA 24-2 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr19:13,836,287...13,836,359
Ensembl chr19:13,836,287...13,836,359 		JBrowse link
G MIR27B microRNA 27b acts_upstream_of_or_within IGI (PMID:31124343) ARUK-UCL PMID:31124343 NCBI chr 9:95,085,445...95,085,541
Ensembl chr 9:95,085,445...95,085,541 		JBrowse link
G NAIP NLR family apoptosis inhibitory protein involved_in IDA (PMID:11865055) UniProt PMID:11865055 NCBI chr 5:70,968,166...71,025,339
Ensembl chr 5:70,968,166...71,025,339 		JBrowse link
G NLRP2B NLR family pyrin domain containing 2B involved_in IMP (PMID:24871464) UniProt PMID:24871464 NCBI chr  X:57,677,067...57,680,260
Ensembl chr  X:57,677,067...57,680,260 		JBrowse link
G NOL3 nucleolar protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:67,170,538...67,175,737
Ensembl chr16:67,170,154...67,175,737 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within IMP (PMID:24113711) MGI PMID:24113711 NCBI chr11:66,466,327...66,477,337
Ensembl chr11:66,466,327...66,477,337 		JBrowse link
G PIAS4 protein inhibitor of activated STAT 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20054338) Ensembl
MGI		 PMID:20054338 GO_REF:0000107 NCBI chr19:4,007,736...4,039,386
Ensembl chr19:4,007,736...4,039,386 		JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta acts_upstream_of IGI (PMID:28159925) ARUK-UCL PMID:28159925 NCBI chr 8:30,785,616...30,812,818
Ensembl chr 8:30,774,457...30,814,314 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:12,785,478...12,884,237
Ensembl chr18:12,785,478...12,929,643 		JBrowse link
G PYDC1 pyrin domain containing 1 involved_in IMP
IDA		 (PMID:24871464)
(PMID:12656673)		 UniProt
HGNC-UCL		 PMID:12656673 PMID:24871464 NCBI chr16:31,215,962...31,217,135
Ensembl chr16:31,215,962...31,217,135 		JBrowse link
G PYDC2 pyrin domain containing 2 involved_in IMP (PMID:17339483), (PMID:24871464) UniProt PMID:17339483 PMID:24871464 NCBI chr 3:191,461,163...191,461,456
Ensembl chr 3:191,461,163...191,461,456 		JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase involved_in IMP (PMID:18450452) UniProt PMID:18450452 NCBI chr17:35,005,990...35,089,226
Ensembl chr17:35,005,990...35,089,319 		JBrowse link
G TANK TRAF family member associated NFKB activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:161,136,963...161,236,230
Ensembl chr 2:161,136,908...161,236,230 		JBrowse link
G TJP2 tight junction protein 2 acts_upstream_of_or_within ISO (PMID:22437732) MGI PMID:22437732 NCBI chr 9:69,121,264...69,255,208
Ensembl chr 9:69,121,264...69,274,615 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29415886) Ensembl
MGI		 PMID:29415886 GO_REF:0000107 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885 		JBrowse link
G TRAIP TRAF interacting protein involved_in IDA (PMID:19151749) CACAO PMID:19151749 NCBI chr 3:49,828,601...49,856,564
Ensembl chr 3:49,828,601...49,856,574 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IDA (PMID:11865055) UniProt PMID:11865055 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
G ZNF675 zinc finger protein 675 involved_in IDA (PMID:11751921) BHF-UCL PMID:11751921 NCBI chr19:23,652,801...23,687,212
Ensembl chr19:23,525,631...23,687,220 		JBrowse link
positive regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in IMP (PMID:24813629) BHF-UCL PMID:24813629 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G CASP1 caspase 1 involved_in IMP (PMID:16920334) UniProt PMID:16920334 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP4 caspase 4 involved_in IDA (PMID:16920334) UniProt PMID:16920334 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366 		JBrowse link
G CPNE1 copine 1 involved_in IMP
IBA		 (PMID:14674885) UniProt
GO_Central		 PMID:14674885 GO_REF:0000033 NCBI chr20:35,626,044...35,664,900
Ensembl chr20:35,626,031...35,664,956 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in IMP (PMID:24790089) UniProt PMID:24790089 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B involved_in IMP (PMID:24790089) UniProt PMID:24790089 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISS (PMID:8661146) ARUK-UCL PMID:8661146 NCBI chr 1:30,732,469...30,757,774
Ensembl chr 1:30,732,469...30,757,774 		JBrowse link
G MIR1246 microRNA 1246 acts_upstream_of IGI (PMID:28159925) ARUK-UCL PMID:28159925 NCBI chr 2:176,600,980...176,601,052
Ensembl chr 2:176,600,980...176,601,052 		JBrowse link
G MMP8 matrix metallopeptidase 8 involved_in IEA
ISS		 (PMID:25049354) Ensembl
ARUK-UCL		 PMID:25049354 GO_REF:0000107 NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IDA (PMID:23453807) ParkinsonsUK-UCL PMID:23453807 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,912...136,926,607 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20054338) Ensembl
MGI		 PMID:20054338 GO_REF:0000107 NCBI chr 9:116,687,305...116,701,299
Ensembl chr 9:116,687,305...116,701,300 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K involved_in IMP (PMID:26707646) FlyBase PMID:26707646 NCBI chr 4:39,698,136...39,782,792
Ensembl chr 4:39,698,109...39,782,792 		JBrowse link
regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP8 caspase 8 involved_in TAS Reactome Reactome:R-HSA-5357905 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase involved_in IDA
IEA
TAS		 (PMID:26997266), (PMID:27458237), (PMID:27591049) UniProt
Ensembl
Reactome		 PMID:26997266 PMID:27458237 PMID:27591049 GO_REF:0000107 Reactome:R-HSA-5357905 NCBI chr16:50,742,086...50,801,935
Ensembl chr16:50,742,050...50,801,935 		JBrowse link
G EXT1 exostosin glycosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29415886) Ensembl
MGI		 PMID:29415886 GO_REF:0000107 NCBI chr 8:117,794,490...118,111,826
Ensembl chr 8:117,794,490...118,111,826 		JBrowse link
G HIPK1 homeodomain interacting protein kinase 1 involved_in IDA (PMID:15701637) UniProt PMID:15701637 NCBI chr 1:113,929,324...113,977,869
Ensembl chr 1:113,929,324...113,977,869 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-5357905 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G MAPKAPK2 MAPK activated protein kinase 2 involved_in TAS Reactome Reactome:R-HSA-5357905 NCBI chr 1:206,684,905...206,734,281
Ensembl chr 1:206,684,905...206,734,281 		JBrowse link
G MIB2 MIB E3 ubiquitin protein ligase 2 involved_in TAS Reactome Reactome:R-HSA-5357905 NCBI chr 1:1,613,731...1,630,605
Ensembl chr 1:1,615,454...1,630,605 		JBrowse link
G NKIRAS1 NFKB inhibitor interacting Ras like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25220458) Ensembl
MGI		 PMID:25220458 GO_REF:0000107 NCBI chr 3:23,889,951...23,946,562
Ensembl chr 3:23,889,951...23,946,591 		JBrowse link
G NKIRAS2 NFKB inhibitor interacting Ras like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25220458) Ensembl
MGI		 PMID:25220458 GO_REF:0000107 NCBI chr17:42,017,576...42,025,641
Ensembl chr17:42,011,382...42,025,644 		JBrowse link
G OTULIN OTU deubiquitinase with linear linkage specificity involved_in IDA
IBA
IEA		 (PMID:26997266) UniProt
GO_Central
Ensembl		 PMID:26997266 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:14,664,718...14,716,525
Ensembl chr 5:14,664,664...14,699,850 		JBrowse link
G PIAS3 protein inhibitor of activated STAT 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17442941) Ensembl
MGI		 PMID:17442941 GO_REF:0000107 NCBI chr 1:145,848,522...145,859,081
Ensembl chr 1:145,848,522...145,859,836 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IMP (PMID:14730312) UniProt PMID:14730312 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G SHARPIN SHANK associated RH domain interactor involved_in IDA
IEA		 (PMID:21455173) UniProt
Ensembl		 PMID:21455173 GO_REF:0000107 NCBI chr 8:144,098,637...144,103,773
Ensembl chr 8:144,098,633...144,108,124 		JBrowse link
G SPATA2 spermatogenesis associated 2 involved_in IEA
IBA
IDA		 (PMID:27307491), (PMID:27458237), (PMID:27545878), (PMID:27591049) Ensembl
TreeGrafter
GO_Central
UniProt		 PMID:27307491 PMID:27458237 PMID:27545878 PMID:27591049 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr20:49,903,391...49,915,529
Ensembl chr20:49,903,391...49,915,529 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IDA (PMID:20577214) UniProt PMID:20577214 NCBI chr17:76,383,204...76,387,855
Ensembl chr17:76,376,584...76,387,860 		JBrowse link
G SPPL2A signal peptide peptidase like 2A involved_in TAS Reactome Reactome:R-HSA-5357905 NCBI chr15:50,702,266...50,765,706
Ensembl chr15:50,702,266...50,765,948 		JBrowse link
G SPPL2B signal peptide peptidase like 2B involved_in TAS Reactome Reactome:R-HSA-5357905 NCBI chr19:2,328,684...2,355,095
Ensembl chr19:2,328,615...2,355,095 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IMP (PMID:19151749) CACAO PMID:19151749 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in TAS Reactome Reactome:R-HSA-5357905 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25220458) Ensembl
MGI		 PMID:25220458 GO_REF:0000107 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 involved_in TAS Reactome Reactome:R-HSA-5357905 NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150 		JBrowse link
tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN4 actinin alpha 4 involved_in IDA (PMID:25411248) UniProt PMID:25411248 NCBI chr19:38,647,649...38,731,589
Ensembl chr19:38,647,649...38,731,589 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G AIM2 absent in melanoma 2 involved_in IDA (PMID:16432157) UniProt PMID:16432157 NCBI chr 1:159,055,051...159,147,132
Ensembl chr 1:159,061,599...159,187,843 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr 1:155,946,854...155,979,617
Ensembl chr 1:155,946,851...156,007,070 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 involved_in TAS Reactome Reactome:R-HSA-5668541 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in TAS Reactome Reactome:R-HSA-5668541 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G CARD14 caspase recruitment domain family member 14 involved_in IMP (PMID:21302310) UniProt PMID:21302310 NCBI chr17:80,170,030...80,209,331
Ensembl chr17:80,169,992...80,216,073 		JBrowse link
G CD70 CD70 molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr19:6,581,648...6,591,150
Ensembl chr19:6,583,183...6,604,103 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex involved_in IEA
IMP
IBA		 (PMID:12656673) TreeGrafter
ARUK-UCL
GO_Central		 PMID:12656673 GO_REF:0000033 GO_REF:0000118 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G COMMD7 COMM domain containing 7 involved_in IDA
IBA		 (PMID:15799966) UniProt
GO_Central		 PMID:15799966 GO_REF:0000033 NCBI chr20:32,702,699...32,743,467
Ensembl chr20:32,702,699...32,743,467 		JBrowse link
G EDA2R ectodysplasin A2 receptor involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:66,595,637...66,639,269
Ensembl chr  X:66,595,637...66,639,298 		JBrowse link
G EIF5A eukaryotic translation initiation factor 5A involved_in IDA (PMID:17187778) UniProt PMID:17187778 NCBI chr17:7,306,999...7,312,463
Ensembl chr17:7,306,999...7,312,463 		JBrowse link
G FAS Fas cell surface death receptor involved_in IEA GOC GO_REF:0000108 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FOXO3 forkhead box O3 involved_in IMP (PMID:15084260) UniProt PMID:15084260 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in IEA
IMP
IBA		 (PMID:12656673), (PMID:15084260), (PMID:25816133) TreeGrafter
UniProt
GO_Central		 PMID:12656673 PMID:15084260 PMID:25816133 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G ILK integrin linked kinase involved_in IMP (PMID:21343177) CAFA PMID:21343177 NCBI chr11:6,603,774...6,610,870
Ensembl chr11:6,603,708...6,610,874 		JBrowse link
G JAK2 Janus kinase 2 involved_in IDA (PMID:8609418) BHF-UCL PMID:8609418 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G KRT18 keratin 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10747083) Ensembl
MGI		 PMID:10747083 GO_REF:0000107 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906 		JBrowse link
G KRT8 keratin 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10747083) Ensembl
MGI		 PMID:10747083 GO_REF:0000107 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954 		JBrowse link
G LIMS1 LIM zinc finger domain containing 1 involved_in IMP (PMID:21343177) CAFA PMID:21343177 NCBI chr 2:108,533,671...108,687,246
Ensembl chr 2:108,533,671...108,687,246 		JBrowse link
G MIR34A microRNA 34a involved_in IDA (PMID:26949937) ARUK-UCL PMID:26949937 NCBI chr 1:9,151,668...9,151,777
Ensembl chr 1:9,151,668...9,151,777 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in IDA (PMID:25038658) CAFA PMID:25038658 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NSMAF neutral sphingomyelinase activation associated factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:58,583,504...58,659,853
Ensembl chr 8:58,583,508...58,659,853 		JBrowse link
G PLVAP plasmalemma vesicle associated protein involved_in IDA (PMID:19420356) UniProt PMID:19420356 NCBI chr19:17,351,455...17,377,342
Ensembl chr19:17,351,450...17,377,342 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IMP (PMID:8670418) UniProt PMID:8670418 NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IDA (PMID:12656673) HGNC-UCL PMID:12656673 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IGI
IMP
IDA		 (PMID:28159925)
(PMID:23878390)
(PMID:21343177), (PMID:25411248)		 ARUK-UCL
BHF-UCL
UniProt		 PMID:21343177 PMID:23878390 PMID:25411248 PMID:28159925 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in IC (PMID:8612133) BHF-UCL PMID:8612133 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G RRAGA Ras related GTP binding A involved_in IDA (PMID:8995684) UniProt PMID:8995684 NCBI chr 9:19,049,427...19,051,025
Ensembl chr 9:19,049,427...19,051,025 		JBrowse link
G ST18 ST18 C2H2C-type zinc finger transcription factor involved_in IMP (PMID:18676404) UniProt PMID:18676404 NCBI chr 8:52,110,838...52,409,879
Ensembl chr 8:52,110,838...52,460,959 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 involved_in IDA (PMID:10848577) UniProt PMID:10848577 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G TIFA TRAF interacting protein with forkhead associated domain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:112,274,537...112,285,904
Ensembl chr 4:112,272,968...112,285,955 		JBrowse link
G TMSB4X thymosin beta 4 X-linked acts_upstream_of_or_within_positive_effect IMP (PMID:21343177) CAFA PMID:21343177 NCBI chr  X:12,975,110...12,977,223
Ensembl chr  X:12,975,110...12,977,227 		JBrowse link
G TNF tumor necrosis factor involved_in
acts_upstream_of_or_within		 IDA
ISO
IEA
IBA
NAS
IMP
TAS		 (PMID:28159925), (PMID:31824476)
(PMID:3898078)
(PMID:23878390)
(PMID:10748004)
(PMID:24966471)		 ARUK-UCL
MGI
TreeGrafter
GO_Central
BHF-UCL
Ensembl		 PMID:3898078 PMID:10748004 PMID:23878390 PMID:24966471 PMID:28159925 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF11A TNF receptor superfamily member 11a involved_in ISS
IBA
IMP
IEA		 (PMID:19940926)
(PMID:18606301)		 BHF-UCL
GO_Central
Ensembl		 PMID:18606301 PMID:19940926 GO_REF:0000033 GO_REF:0000107 NCBI chr18:62,325,310...62,391,288
Ensembl chr18:62,325,287...62,391,288 		JBrowse link
G TNFRSF13C TNF receptor superfamily member 13C involved_in IEA InterPro GO_REF:0000002 NCBI chr22:41,922,032...41,926,806
Ensembl chr22:41,922,032...41,926,806 		JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:2,554,234...2,563,829
Ensembl chr 1:2,555,639...2,565,382 		JBrowse link
G TNFRSF17 TNF receptor superfamily member 17 involved_in IEA InterPro GO_REF:0000002 NCBI chr16:11,965,210...11,968,068
Ensembl chr16:11,965,210...11,968,068 		JBrowse link
G TNFRSF18 TNF receptor superfamily member 18 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:1,203,508...1,206,592
Ensembl chr 1:1,203,508...1,206,592 		JBrowse link
G TNFRSF19 TNF receptor superfamily member 19 involved_in IEA GOC GO_REF:0000108 NCBI chr13:23,570,412...23,676,093
Ensembl chr13:23,570,370...23,676,104 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A acts_upstream_of_or_within
involved_in		 ISO
IEA
IMP
TAS		 (MGI:2152007|PMID:11588035)
(PMID:25816133)
(PMID:24966471)		 RGD
GOC
Ensembl
GOC
UniProt
ARUK-UCL
InterPro		 PMID:11588035 PMID:20967881 PMID:24966471 PMID:25816133 GO_REF:0000002 GO_REF:0000107 GO_REF:0000108 MGI:2152007 RGD:5130945 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B involved_in IEA
TAS		 (PMID:24966471) GOC
ARUK-UCL		 PMID:24966471 GO_REF:0000108 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TNFRSF25 TNF receptor superfamily member 25 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:6,460,786...6,466,173
Ensembl chr 1:6,460,786...6,466,175 		JBrowse link
G TNFRSF4 TNF receptor superfamily member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2683815|PMID:14635034) GOC
GOC		 PMID:14635034 GO_REF:0000108 MGI:2683815 NCBI chr 1:1,211,340...1,214,153
Ensembl chr 1:1,211,326...1,214,153 		JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO
IDA
ISS		 (PMID:17442941), (PMID:18269914), (PMID:22437732)
(PMID:18606301)
(PMID:19940926)		 Ensembl
MGI
BHF-UCL		 PMID:17442941 PMID:18269914 PMID:18606301 PMID:19940926 PMID:22437732 GO_REF:0000107 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
G TNFSF13B TNF superfamily member 13b involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:108,269,629...108,308,484
Ensembl chr13:108,251,240...108,308,484 		JBrowse link
G TNFSF18 TNF superfamily member 18 involved_in IEA
IBA
ISS		 InterPro
TreeGrafter
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:173,039,202...173,050,941
Ensembl chr 1:173,039,202...173,050,941 		JBrowse link
G TP53 tumor protein p53 involved_in IGI (PMID:22499991) BHF-UCL PMID:22499991 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TRADD TNFRSF1A associated via death domain involved_in TAS
IDA		 (PMID:8612133)
(PMID:7758105)		 BHF-UCL
UniProt		 PMID:7758105 PMID:8612133 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,154,185...67,159,909 		JBrowse link
G TRAF1 TNF receptor associated factor 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:120,902,393...120,929,171
Ensembl chr 9:120,902,393...120,929,173 		JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in ISO
IBA
IEA
IDA		 (PMID:11907583) RGD
GO_Central
TreeGrafter
Ensembl
InterPro
UniProt		 PMID:10713108 PMID:11907583 PMID:20967881 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:2298798 RGD:5130945 NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,912...136,926,607 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA
IBA
IMP		 (PMID:20185819) InterPro
GO_Central
Ensembl
UniProt		 PMID:20185819 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:111,555,381...111,605,878
Ensembl chr 6:111,555,381...111,606,906 		JBrowse link
G TRAF4 TNF receptor associated factor 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:28,744,011...28,750,956
Ensembl chr17:28,744,011...28,750,956 		JBrowse link
G TRAF5 TNF receptor associated factor 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:211,326,635...211,374,946
Ensembl chr 1:211,326,615...211,374,946 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TXNDC17 thioredoxin domain containing 17 involved_in IMP (PMID:14607844) UniProt PMID:14607844 NCBI chr17:6,641,060...6,644,541
Ensembl chr17:6,640,985...6,644,541 		JBrowse link
G UMOD uromodulin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28990932) Ensembl
MGI		 PMID:28990932 GO_REF:0000107 NCBI chr16:20,333,051...20,356,301
Ensembl chr16:20,333,051...20,356,301 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19613
    response to stimulus 10170
      response to chemical 5025
        response to peptide 1347
          response to cytokine 1323
            cellular response to cytokine stimulus 1186
              cellular response to tumor necrosis factor 291
                tumor necrosis factor-mediated signaling pathway + 124
paths to the root