EDA2R (ectodysplasin A2 receptor)

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Keyword

Gene: EDA2R (ectodysplasin A2 receptor) Homo sapiens

Symbol:

EDA2R

Name:

ectodysplasin A2 receptor

Description:

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2011]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

EDA-A2 receptor; EDA-A2R; EDAA2R; OTTHUMP00000023448; OTTHUMP00000023449; TNFRSF27; tumor necrosis factor receptor superfamily member 27; tumor necrosis factor receptor superfamily member XEDAR; X-linked ectodysplasin-A2 receptor; XEDAR

Orthologs:

Mus musculus : Eda2r (ectodysplasin A2 receptor) MGI
Rattus norvegicus : Eda2r (ectodysplasin A2 receptor)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	X	65,823,549 - 65,867,176	-	NCBI
Human Genome Assembly HuRef	X	59,642,932 - 59,686,455	-	NCBI
Human Genome Assembly GRCh37	X	65,815,479 - 65,859,140	-	NCBI
Human Celera Assembly	X	66,163,047 - 66,183,441	-	NCBI
Human Genome Assembly Build 36	X	65,732,204 - 65,752,598	-	NCBI
Human Cytogenetic Map	X	q12		NCBI
Human Genome Assembly	X	65,598,503 - 65,618,894		NCBI