ZNF268 (zinc finger protein 268) - Rat Genome Database

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Gene: ZNF268 (zinc finger protein 268) Homo sapiens
Analyze
Symbol: ZNF268
Name: zinc finger protein 268
RGD ID: 1347350
HGNC Page HGNC:13061
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of protein metabolic process; regulation of apoptotic process; and regulation of transcription by RNA polymerase II. Located in cytosol and nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: HZF3; MGC126498; zinc finger protein 3; zinc finger protein HZF3
RGD Orthologs
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812133,181,495 - 133,214,832 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12133,181,409 - 133,214,832 (+)EnsemblGRCh38hg38GRCh38
GRCh3712133,758,081 - 133,791,418 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612132,268,068 - 132,289,534 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412132,368,494 - 132,389,811NCBI
Celera12133,458,293 - 133,483,993 (+)NCBICelera
Cytogenetic Map12q24.33NCBI
HuRef12130,536,912 - 130,562,408 (+)NCBIHuRef
CHM1_112133,577,925 - 133,603,626 (+)NCBICHM1_1
T2T-CHM13v2.012133,238,807 - 133,272,083 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA,IEA)
cytosol  (IDA)
nucleoplasm  (IEA)
nucleus  (IBA,IDA,IEA,NAS)

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7865130   PMID:11311945   PMID:12477932   PMID:12822888   PMID:14702039   PMID:15146197   PMID:15547661   PMID:16344560   PMID:16735226   PMID:16787922   PMID:16865230   PMID:18375384  
PMID:18677094   PMID:18774934   PMID:18949428   PMID:19274049   PMID:21873635   PMID:22235304   PMID:23091055   PMID:23665872   PMID:23946776   PMID:25609649   PMID:26186194   PMID:26496610  
PMID:28514442   PMID:30862715   PMID:31835635   PMID:31862882   PMID:33961781   PMID:35271311   PMID:35563538  


Genomics

Comparative Map Data
ZNF268
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812133,181,495 - 133,214,832 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12133,181,409 - 133,214,832 (+)EnsemblGRCh38hg38GRCh38
GRCh3712133,758,081 - 133,791,418 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612132,268,068 - 132,289,534 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412132,368,494 - 132,389,811NCBI
Celera12133,458,293 - 133,483,993 (+)NCBICelera
Cytogenetic Map12q24.33NCBI
HuRef12130,536,912 - 130,562,408 (+)NCBIHuRef
CHM1_112133,577,925 - 133,603,626 (+)NCBICHM1_1
T2T-CHM13v2.012133,238,807 - 133,272,083 (+)NCBIT2T-CHM13v2.0
Znf268
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495548217,009 - 38,746 (-)NCBIChiLan1.0ChiLan1.0
ZNF268
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210141,293,880 - 141,327,265 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112141,290,401 - 141,318,255 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012130,661,530 - 130,686,086 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112135,265,029 - 135,290,457 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12135,265,137 - 135,290,457 (+)Ensemblpanpan1.1panPan2
ZNF268
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12642,480 - 81,811 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2645,630 - 108,235 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2683,849 - 123,139 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02698,274 - 137,614 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2698,274 - 137,581 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12640,264 - 79,594 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.026126,348 - 165,637 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02658,541 - 97,835 (-)NCBIUU_Cfam_GSD_1.0
LOC100154415
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1422,379,611 - 22,395,525 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11422,379,600 - 22,399,987 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21423,738,999 - 23,755,594 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF268
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111128,477,863 - 128,499,251 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11128,478,327 - 128,497,779 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037116,285,025 - 116,307,777 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in ZNF268
50 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 12q24.23-24.33(chr12:118165459-133182322)x3 copy number gain See cases [RCV000050866] Chr12:118165459..133182322 [GRCh38]
Chr12:118603264..133758908 [GRCh37]
Chr12:117087647..132268981 [NCBI36]
Chr12:12q24.23-24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:131924544-133191400)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051346]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051346]|See cases [RCV000051346] Chr12:131924544..133191400 [GRCh38]
Chr12:132409089..133767986 [GRCh37]
Chr12:130975042..132278059 [NCBI36]
Chr12:12q24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123444758-133191400)x3 copy number gain See cases [RCV000051151] Chr12:123444758..133191400 [GRCh38]
Chr12:123929305..133767986 [GRCh37]
Chr12:122495258..132278059 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:131049491-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053717]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053717]|See cases [RCV000053717] Chr12:131049491..133191400 [GRCh38]
Chr12:131534036..133767986 [GRCh37]
Chr12:130099989..132278059 [NCBI36]
Chr12:12q24.33		 pathogenic
GRCh38/hg38 12q24.23-24.33(chr12:119417382-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053691]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053691]|See cases [RCV000053691] Chr12:119417382..133191400 [GRCh38]
Chr12:119855187..133767986 [GRCh37]
Chr12:118339570..132278059 [NCBI36]
Chr12:12q24.23-24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123365769-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053693]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053693]|See cases [RCV000053693] Chr12:123365769..133191400 [GRCh38]
Chr12:123850316..133767986 [GRCh37]
Chr12:122416269..132278059 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:132576614-133191400)x1 copy number loss See cases [RCV000133777] Chr12:132576614..133191400 [GRCh38]
Chr12:133153200..133767986 [GRCh37]
Chr12:131663273..132278059 [NCBI36]
Chr12:12q24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:133187321-133196807)x3 copy number gain See cases [RCV000134718] Chr12:133187321..133196807 [GRCh38]
Chr12:133763907..133773393 [GRCh37]
Chr12:132273980..132283466 [NCBI36]
Chr12:12q24.33		 benign
GRCh38/hg38 12q24.33(chr12:133136361-133202431)x3 copy number gain See cases [RCV000134419] Chr12:133136361..133202431 [GRCh38]
Chr12:133712947..133779017 [GRCh37]
Chr12:132223020..132289090 [NCBI36]
Chr12:12q24.33		 benign
GRCh38/hg38 12q24.33(chr12:131650542-133191400)x1 copy number loss See cases [RCV000134173] Chr12:131650542..133191400 [GRCh38]
Chr12:132135087..133767986 [GRCh37]
Chr12:130701040..132278059 [NCBI36]
Chr12:12q24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:133102300-133182263)x3 copy number gain See cases [RCV000135146] Chr12:133102300..133182263 [GRCh38]
Chr12:133678886..133758849 [GRCh37]
Chr12:132188959..132268922 [NCBI36]
Chr12:12q24.33		 likely benign
GRCh38/hg38 12q24.31-24.33(chr12:123509825-133191400)x3 copy number gain See cases [RCV000135535] Chr12:123509825..133191400 [GRCh38]
Chr12:123994372..133767986 [GRCh37]
Chr12:122560325..132278059 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:120697672-133202490)x3 copy number gain See cases [RCV000137651] Chr12:120697672..133202490 [GRCh38]
Chr12:121135475..133779076 [GRCh37]
Chr12:119619858..132289149 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.33(chr12:132966304-133202490)x1 copy number loss See cases [RCV000137311] Chr12:132966304..133202490 [GRCh38]
Chr12:133542890..133779076 [GRCh37]
Chr12:132052963..132289149 [NCBI36]
Chr12:12q24.33		 likely benign|uncertain significance
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33		 pathogenic
GRCh38/hg38 12q24.21-24.33(chr12:114268403-133201316)x3 copy number gain See cases [RCV000143656] Chr12:114268403..133201316 [GRCh38]
Chr12:114706208..133777902 [GRCh37]
Chr12:113190591..132287975 [NCBI36]
Chr12:12q24.21-24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic|likely pathogenic
GRCh37/hg19 12q24.33(chr12:131749518-133777902)x1 copy number loss See cases [RCV000449052] Chr12:131749518..133777902 [GRCh37]
Chr12:12q24.33		 pathogenic
NM_003415.3(ZNF268):c.1216C>T (p.His406Tyr) single nucleotide variant not specified [RCV004309677] Chr12:133202902 [GRCh38]
Chr12:133779488 [GRCh37]
Chr12:12q24.33		 uncertain significance
GRCh37/hg19 12q24.33(chr12:132382041-133777902)x1 copy number loss See cases [RCV000446819] Chr12:132382041..133777902 [GRCh37]
Chr12:12q24.33		 pathogenic
GRCh37/hg19 12q24.33(chr12:133324869-133777902)x3 copy number gain See cases [RCV000446483] Chr12:133324869..133777902 [GRCh37]
Chr12:12q24.33		 pathogenic
GRCh37/hg19 12q24.33(chr12:133727565-133772989)x3 copy number gain See cases [RCV000446606] Chr12:133727565..133772989 [GRCh37]
Chr12:12q24.33		 benign
GRCh37/hg19 12q24.33(chr12:133683528-133772989)x3 copy number gain See cases [RCV000447703] Chr12:133683528..133772989 [GRCh37]
Chr12:12q24.33		 likely benign
GRCh37/hg19 12q24.33(chr12:131862310-133777902)x1 copy number loss See cases [RCV000447834] Chr12:131862310..133777902 [GRCh37]
Chr12:12q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
NM_003415.3(ZNF268):c.1313A>G (p.His438Arg) single nucleotide variant not specified [RCV004315100] Chr12:133202999 [GRCh38]
Chr12:133779585 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.441A>G (p.Pro147=) single nucleotide variant not specified [RCV004331070] Chr12:133191987 [GRCh38]
Chr12:133768573 [GRCh37]
Chr12:12q24.33		 likely benign
NM_003415.3(ZNF268):c.1949C>T (p.Thr650Met) single nucleotide variant not specified [RCV004291007] Chr12:133203635 [GRCh38]
Chr12:133780221 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1915C>T (p.Pro639Ser) single nucleotide variant not specified [RCV004284222] Chr12:133203601 [GRCh38]
Chr12:133780187 [GRCh37]
Chr12:12q24.33		 uncertain significance
GRCh37/hg19 12q24.33(chr12:133046203-133777902)x3 copy number gain See cases [RCV000512177] Chr12:133046203..133777902 [GRCh37]
Chr12:12q24.33		 uncertain significance
GRCh37/hg19 12q24.33(chr12:130973400-133777902)x3 copy number gain not provided [RCV000683469] Chr12:130973400..133777902 [GRCh37]
Chr12:12q24.33		 likely pathogenic
GRCh37/hg19 12q24.23-24.33(chr12:120367241-133777645)x3 copy number gain not provided [RCV000738070] Chr12:120367241..133777645 [GRCh37]
Chr12:12q24.23-24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
NM_003415.3(ZNF268):c.1491G>T (p.Met497Ile) single nucleotide variant not specified [RCV004304288] Chr12:133203177 [GRCh38]
Chr12:133779763 [GRCh37]
Chr12:12q24.33		 uncertain significance
GRCh37/hg19 12q24.31-24.33(chr12:125451405-133810935) copy number gain not provided [RCV000767827] Chr12:125451405..133810935 [GRCh37]
Chr12:12q24.31-24.33		 pathogenic
GRCh37/hg19 12q24.33(chr12:131363916-133777645)x3 copy number gain See cases [RCV000790570] Chr12:131363916..133777645 [GRCh37]
Chr12:12q24.33		 pathogenic
GRCh37/hg19 12q24.33(chr12:132975658-133777902)x1 copy number loss not provided [RCV000847172] Chr12:132975658..133777902 [GRCh37]
Chr12:12q24.33		 uncertain significance
GRCh37/hg19 12q24.32-24.33(chr12:126470636-133777902)x1 copy number loss not provided [RCV000848702] Chr12:126470636..133777902 [GRCh37]
Chr12:12q24.32-24.33		 uncertain significance
NM_003415.3(ZNF268):c.2561A>G (p.His854Arg) single nucleotide variant not specified [RCV004286320] Chr12:133204247 [GRCh38]
Chr12:133780833 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.525G>A (p.Thr175=) single nucleotide variant not specified [RCV004281635] Chr12:133202211 [GRCh38]
Chr12:133778797 [GRCh37]
Chr12:12q24.33		 likely benign
NM_003415.3(ZNF268):c.2037G>T (p.Leu679Phe) single nucleotide variant not provided [RCV001707047] Chr12:133203723 [GRCh38]
Chr12:133780309 [GRCh37]
Chr12:12q24.33		 benign
GRCh37/hg19 12q24.22-24.33(chr12:117461902-133841395)x3 copy number gain Neurodevelopmental disorder with nonspecific brain abnormalities and with or without seizures [RCV001801213] Chr12:117461902..133841395 [GRCh37]
Chr12:12q24.22-24.33		 likely pathogenic
GRCh37/hg19 12q24.33(chr12:133520357-133777902)x1 copy number loss not provided [RCV001829100] Chr12:133520357..133777902 [GRCh37]
Chr12:12q24.33		 likely benign
NM_003415.3(ZNF268):c.2048T>C (p.Leu683Pro) single nucleotide variant not specified [RCV004330720] Chr12:133203734 [GRCh38]
Chr12:133780320 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2350G>C (p.Glu784Gln) single nucleotide variant not specified [RCV004104912] Chr12:133204036 [GRCh38]
Chr12:133780622 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1246T>A (p.Tyr416Asn) single nucleotide variant not specified [RCV004166766] Chr12:133202932 [GRCh38]
Chr12:133779518 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1966A>G (p.Ile656Val) single nucleotide variant not specified [RCV004120237] Chr12:133203652 [GRCh38]
Chr12:133780238 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.593A>G (p.Gln198Arg) single nucleotide variant not specified [RCV004192796] Chr12:133202279 [GRCh38]
Chr12:133778865 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2630C>T (p.Ser877Phe) single nucleotide variant not specified [RCV004197167] Chr12:133204316 [GRCh38]
Chr12:133780902 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1874C>T (p.Ser625Leu) single nucleotide variant not specified [RCV004186172] Chr12:133203560 [GRCh38]
Chr12:133780146 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1361C>T (p.Thr454Ile) single nucleotide variant not specified [RCV004216237] Chr12:133203047 [GRCh38]
Chr12:133779633 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2287A>G (p.Arg763Gly) single nucleotide variant not specified [RCV004204454] Chr12:133203973 [GRCh38]
Chr12:133780559 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2128T>C (p.Tyr710His) single nucleotide variant not specified [RCV004196744] Chr12:133203814 [GRCh38]
Chr12:133780400 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.406G>A (p.Gly136Arg) single nucleotide variant not specified [RCV004142379] Chr12:133191952 [GRCh38]
Chr12:133768538 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2575A>C (p.Thr859Pro) single nucleotide variant not specified [RCV004172124] Chr12:133204261 [GRCh38]
Chr12:133780847 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2315G>A (p.Arg772Gln) single nucleotide variant not specified [RCV004201083] Chr12:133204001 [GRCh38]
Chr12:133780587 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1292T>G (p.Leu431Arg) single nucleotide variant not specified [RCV004121512] Chr12:133202978 [GRCh38]
Chr12:133779564 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2118G>C (p.Arg706Ser) single nucleotide variant not specified [RCV004122784] Chr12:133203804 [GRCh38]
Chr12:133780390 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.418T>C (p.Cys140Arg) single nucleotide variant not specified [RCV004187514] Chr12:133191964 [GRCh38]
Chr12:133768550 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1013G>A (p.Arg338Lys) single nucleotide variant not specified [RCV004204491] Chr12:133202699 [GRCh38]
Chr12:133779285 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.217A>G (p.Lys73Glu) single nucleotide variant not specified [RCV004174687] Chr12:133188055 [GRCh38]
Chr12:133764641 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2419C>T (p.Pro807Ser) single nucleotide variant not specified [RCV004114617] Chr12:133204105 [GRCh38]
Chr12:133780691 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2575A>G (p.Thr859Ala) single nucleotide variant not specified [RCV004157918] Chr12:133204261 [GRCh38]
Chr12:133780847 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2149A>G (p.Thr717Ala) single nucleotide variant not specified [RCV004143173] Chr12:133203835 [GRCh38]
Chr12:133780421 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1978G>C (p.Gly660Arg) single nucleotide variant not specified [RCV004099171] Chr12:133203664 [GRCh38]
Chr12:133780250 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1099A>G (p.Lys367Glu) single nucleotide variant not specified [RCV004182533] Chr12:133202785 [GRCh38]
Chr12:133779371 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2125T>G (p.Ser709Ala) single nucleotide variant not specified [RCV004180732] Chr12:133203811 [GRCh38]
Chr12:133780397 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1687A>G (p.Lys563Glu) single nucleotide variant not specified [RCV004074987] Chr12:133203373 [GRCh38]
Chr12:133779959 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2497G>T (p.Val833Phe) single nucleotide variant not specified [RCV004135767] Chr12:133204183 [GRCh38]
Chr12:133780769 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2615C>T (p.Ala872Val) single nucleotide variant not specified [RCV004169746] Chr12:133204301 [GRCh38]
Chr12:133780887 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1478G>A (p.Ser493Asn) single nucleotide variant not specified [RCV004092434] Chr12:133203164 [GRCh38]
Chr12:133779750 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1967T>C (p.Ile656Thr) single nucleotide variant not specified [RCV004081115] Chr12:133203653 [GRCh38]
Chr12:133780239 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.11G>C (p.Arg4Thr) single nucleotide variant not specified [RCV004332584] Chr12:133182008 [GRCh38]
Chr12:133758594 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.29T>C (p.Ile10Thr) single nucleotide variant not specified [RCV004256687] Chr12:133182026 [GRCh38]
Chr12:133758612 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2688A>C (p.Glu896Asp) single nucleotide variant not specified [RCV004277466] Chr12:133204374 [GRCh38]
Chr12:133780960 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.817G>A (p.Glu273Lys) single nucleotide variant not specified [RCV004333768] Chr12:133202503 [GRCh38]
Chr12:133779089 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.688C>A (p.His230Asn) single nucleotide variant not specified [RCV004286986] Chr12:133202374 [GRCh38]
Chr12:133778960 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1160C>T (p.Pro387Leu) single nucleotide variant not specified [RCV004266127] Chr12:133202846 [GRCh38]
Chr12:133779432 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2569A>G (p.Met857Val) single nucleotide variant not specified [RCV004259110] Chr12:133204255 [GRCh38]
Chr12:133780841 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.779A>G (p.Lys260Arg) single nucleotide variant not specified [RCV004333036] Chr12:133202465 [GRCh38]
Chr12:133779051 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2395A>G (p.Met799Val) single nucleotide variant not specified [RCV004354325] Chr12:133204081 [GRCh38]
Chr12:133780667 [GRCh37]
Chr12:12q24.33		 uncertain significance
GRCh37/hg19 12q24.31-24.33(chr12:121551496-133777902)x3 copy number gain not provided [RCV003484881] Chr12:121551496..133777902 [GRCh37]
Chr12:12q24.31-24.33		 pathogenic
GRCh37/hg19 12q24.31-24.33(chr12:120880079-133777902)x3 copy number gain not provided [RCV003484880] Chr12:120880079..133777902 [GRCh37]
Chr12:12q24.31-24.33		 pathogenic
NM_003415.3(ZNF268):c.957C>T (p.Leu319=) single nucleotide variant not provided [RCV003398321] Chr12:133202643 [GRCh38]
Chr12:133779229 [GRCh37]
Chr12:12q24.33		 likely benign
NM_003415.3(ZNF268):c.2437T>C (p.Cys813Arg) single nucleotide variant not specified [RCV004494138] Chr12:133204123 [GRCh38]
Chr12:133780709 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.251T>C (p.Met84Thr) single nucleotide variant not specified [RCV004494140] Chr12:133191505 [GRCh38]
Chr12:133768091 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.839G>A (p.Cys280Tyr) single nucleotide variant not specified [RCV004494148] Chr12:133202525 [GRCh38]
Chr12:133779111 [GRCh37]
Chr12:12q24.33		 likely benign
NM_003415.3(ZNF268):c.1394T>C (p.Ile465Thr) single nucleotide variant not specified [RCV004494133] Chr12:133203080 [GRCh38]
Chr12:133779666 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2263A>C (p.Ser755Arg) single nucleotide variant not specified [RCV004494137] Chr12:133203949 [GRCh38]
Chr12:133780535 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.505A>G (p.Lys169Glu) single nucleotide variant not specified [RCV004494144] Chr12:133202191 [GRCh38]
Chr12:133778777 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2834A>G (p.Asp945Gly) single nucleotide variant not specified [RCV004494143] Chr12:133204520 [GRCh38]
Chr12:133781106 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1151G>A (p.Gly384Glu) single nucleotide variant not specified [RCV004494132] Chr12:133202837 [GRCh38]
Chr12:133779423 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1630A>C (p.Ile544Leu) single nucleotide variant not specified [RCV004494134] Chr12:133203316 [GRCh38]
Chr12:133779902 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.1681T>C (p.Cys561Arg) single nucleotide variant not specified [RCV004494135] Chr12:133203367 [GRCh38]
Chr12:133779953 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2056C>T (p.His686Tyr) single nucleotide variant not specified [RCV004494136] Chr12:133203742 [GRCh38]
Chr12:133780328 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2483G>A (p.Arg828Gln) single nucleotide variant not specified [RCV004494139] Chr12:133204169 [GRCh38]
Chr12:133780755 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.2816A>G (p.Gln939Arg) single nucleotide variant not specified [RCV004494142] Chr12:133204502 [GRCh38]
Chr12:133781088 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.662G>T (p.Arg221Ile) single nucleotide variant not specified [RCV004494146] Chr12:133202348 [GRCh38]
Chr12:133778934 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.697T>C (p.Ser233Pro) single nucleotide variant not specified [RCV004494147] Chr12:133202383 [GRCh38]
Chr12:133778969 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.898G>A (p.Glu300Lys) single nucleotide variant not specified [RCV004494149] Chr12:133202584 [GRCh38]
Chr12:133779170 [GRCh37]
Chr12:12q24.33		 uncertain significance
NM_003415.3(ZNF268):c.540A>G (p.Glu180=) single nucleotide variant not specified [RCV004494145] Chr12:133202226 [GRCh38]
Chr12:133778812 [GRCh37]
Chr12:12q24.33		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4735
Count of miRNA genes:1063
Interacting mature miRNAs:1270
Transcripts:ENST00000228289, ENST00000416488, ENST00000500625, ENST00000534953, ENST00000536435, ENST00000536899, ENST00000537565, ENST00000537973, ENST00000539248, ENST00000541009, ENST00000541211, ENST00000541975, ENST00000542711, ENST00000542986, ENST00000546126, ENST00000585488, ENST00000588312, ENST00000591951, ENST00000592241
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D12S1186E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712133,782,784 - 133,782,958UniSTSGRCh37
Celera12133,483,079 - 133,483,253RGD
Cytogenetic Map12q24.33UniSTS
HuRef12130,561,494 - 130,561,668UniSTS
D12S2117  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712133,781,574 - 133,781,717UniSTSGRCh37
Celera12133,481,870 - 133,482,013RGD
Cytogenetic Map12q24.33UniSTS
HuRef12130,560,285 - 130,560,428UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 19 1 60 15 102 14 26 11 63 108 146 100 1 1 2 1
Low 2408 2304 1664 608 1267 450 4116 1870 3619 311 1311 1505 173 1203 2576 4 1
Below cutoff 12 686 2 1 582 1 215 316 52 3 8 1 212

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001165881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001165882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001165883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001165884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001165885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001165886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001165887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_152943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC026786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC226150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF141655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF317549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF385187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF432217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK027712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW138703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY583691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC110542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN255799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB079580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ057356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ057357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ057358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ057359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ057360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ057361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC877507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF455750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X78926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000228289   ⟹   ENSP00000228289
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,474 - 133,205,023 (+)Ensembl
RefSeq Acc Id: ENST00000416488   ⟹   ENSP00000409295
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,409 - 133,193,537 (+)Ensembl
RefSeq Acc Id: ENST00000500625   ⟹   ENSP00000466629
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,503 - 133,202,219 (+)Ensembl
RefSeq Acc Id: ENST00000534953
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,191,721 - 133,202,310 (+)Ensembl
RefSeq Acc Id: ENST00000536435   ⟹   ENSP00000444412
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,495 - 133,214,832 (+)Ensembl
RefSeq Acc Id: ENST00000536899   ⟹   ENSP00000438941
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,514 - 133,205,121 (+)Ensembl
RefSeq Acc Id: ENST00000537973
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,495 - 133,188,153 (+)Ensembl
RefSeq Acc Id: ENST00000539248   ⟹   ENSP00000467781
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,511 - 133,202,440 (+)Ensembl
RefSeq Acc Id: ENST00000541009   ⟹   ENSP00000439539
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,559 - 133,205,173 (+)Ensembl
RefSeq Acc Id: ENST00000541211   ⟹   ENSP00000442446
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,495 - 133,202,350 (+)Ensembl
RefSeq Acc Id: ENST00000541975   ⟹   ENSP00000446153
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,528 - 133,191,608 (+)Ensembl
RefSeq Acc Id: ENST00000542711   ⟹   ENSP00000437858
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,511 - 133,202,647 (+)Ensembl
RefSeq Acc Id: ENST00000542986   ⟹   ENSP00000443721
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,514 - 133,205,173 (+)Ensembl
RefSeq Acc Id: ENST00000546126   ⟹   ENSP00000437410
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,495 - 133,205,114 (+)Ensembl
RefSeq Acc Id: ENST00000585488
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,191,455 - 133,202,169 (+)Ensembl
RefSeq Acc Id: ENST00000588312   ⟹   ENSP00000466622
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,620 - 133,202,348 (+)Ensembl
RefSeq Acc Id: ENST00000591951   ⟹   ENSP00000464721
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,191,497 - 133,202,440 (+)Ensembl
RefSeq Acc Id: ENST00000592241   ⟹   ENSP00000467922
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,620 - 133,202,348 (+)Ensembl
RefSeq Acc Id: ENST00000611984   ⟹   ENSP00000479191
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12133,181,522 - 133,193,537 (+)Ensembl
RefSeq Acc Id: NM_001165881   ⟹   NP_001159353
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812133,181,495 - 133,214,832 (+)NCBI
GRCh3712133,757,995 - 133,783,698 (+)ENTREZGENE
HuRef12130,536,912 - 130,562,408 (+)ENTREZGENE
CHM1_112133,577,990 - 133,603,626 (+)NCBI
T2T-CHM13v2.012133,238,807 - 133,272,083 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001165882   ⟹   NP_001159354
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812133,181,495 - 133,214,832 (+)NCBI
GRCh3712133,757,995 - 133,783,698 (+)ENTREZGENE
HuRef12130,536,912 - 130,562,408 (+)ENTREZGENE
CHM1_112133,577,990 - 133,603,626 (+)NCBI
T2T-CHM13v2.012133,238,807 - 133,272,083 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001165883   ⟹   NP_001159355
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812133,181,495 - 133,214,832 (+)NCBI
GRCh3712133,757,995 - 133,783,698 (+)ENTREZGENE
HuRef12130,536,912 - 130,562,408 (+)ENTREZGENE
CHM1_112133,577,925 - 133,603,626 (+)NCBI
T2T-CHM13v2.012133,238,807 - 133,272,083 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001165884   ⟹   NP_001159356
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812133,181,495 - 133,214,832 (+)NCBI
GRCh3712133,757,995 - 133,783,698 (+)ENTREZGENE
HuRef12130,536,912 - 130,562,408 (+)ENTREZGENE
CHM1_112133,577,925 - 133,603,626 (+)NCBI
T2T-CHM13v2.012133,238,807 - 133,272,083 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001165885   ⟹   NP_001159357
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812133,181,495 - 133,214,832 (+)NCBI
GRCh3712133,757,995 - 133,783,698 (+)ENTREZGENE
HuRef12130,536,912 - 130,562,408 (+)ENTREZGENE
CHM1_112133,577,925 - 133,603,626 (+)NCBI
T2T-CHM13v2.012133,238,807 - 133,272,083 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001165886   ⟹   NP_001159358
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812133,181,495 - 133,214,832 (+)NCBI
GRCh3712133,757,995 - 133,783,698 (+)ENTREZGENE
HuRef12130,536,912 - 130,562,408 (+)ENTREZGENE
CHM1_112133,577,925 - 133,603,626 (+)NCBI
T2T-CHM13v2.012133,238,807 - 133,272,083 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001165887   ⟹   NP_001159359
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812133,181,495 - 133,214,832 (+)NCBI
GRCh3712133,757,995 - 133,783,698 (+)ENTREZGENE
HuRef12130,536,912 - 130,562,408 (+)ENTREZGENE
CHM1_112133,577,925 - 133,603,626 (+)NCBI
T2T-CHM13v2.012133,238,807 - 133,272,083 (+)NCBI
Sequence:
RefSeq Acc Id: NM_003415   ⟹   NP_003406
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812133,181,495 - 133,214,832 (+)NCBI
GRCh3712133,757,995 - 133,783,698 (+)NCBI
Build 3612132,268,068 - 132,289,534 (+)NCBI Archive
HuRef12130,536,912 - 130,562,408 (+)ENTREZGENE
CHM1_112133,577,925 - 133,603,626 (+)NCBI
T2T-CHM13v2.012133,238,807 - 133,272,083 (+)NCBI
Sequence:
RefSeq Acc Id: NM_152943   ⟹   NP_694422
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812133,181,495 - 133,214,832 (+)NCBI
GRCh3712133,757,995 - 133,783,698 (+)NCBI
HuRef12130,536,912 - 130,562,408 (+)ENTREZGENE
CHM1_112133,577,925 - 133,603,626 (+)NCBI
T2T-CHM13v2.012133,238,807 - 133,272,083 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001159353 (Get FASTA)   NCBI Sequence Viewer  
  NP_001159354 (Get FASTA)   NCBI Sequence Viewer  
  NP_001159355 (Get FASTA)   NCBI Sequence Viewer  
  NP_001159356 (Get FASTA)   NCBI Sequence Viewer  
  NP_001159357 (Get FASTA)   NCBI Sequence Viewer  
  NP_001159358 (Get FASTA)   NCBI Sequence Viewer  
  NP_001159359 (Get FASTA)   NCBI Sequence Viewer  
  NP_003406 (Get FASTA)   NCBI Sequence Viewer  
  NP_694422 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG39638 (Get FASTA)   NCBI Sequence Viewer  
  AAG59817 (Get FASTA)   NCBI Sequence Viewer  
  AAI10543 (Get FASTA)   NCBI Sequence Viewer  
  AAK69307 (Get FASTA)   NCBI Sequence Viewer  
  AAL99923 (Get FASTA)   NCBI Sequence Viewer  
  BAG51369 (Get FASTA)   NCBI Sequence Viewer  
  CAA55526 (Get FASTA)   NCBI Sequence Viewer  
  EAW54786 (Get FASTA)   NCBI Sequence Viewer  
  EAW54787 (Get FASTA)   NCBI Sequence Viewer  
  EAW54788 (Get FASTA)   NCBI Sequence Viewer  
  EAW54789 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000228289
  ENSP00000228289.5
  ENSP00000409295.2
  ENSP00000437410.1
  ENSP00000437858
  ENSP00000437858.1
  ENSP00000438941
  ENSP00000438941.1
  ENSP00000439539
  ENSP00000439539.2
  ENSP00000442446
  ENSP00000442446.2
  ENSP00000443721.2
  ENSP00000444412
  ENSP00000444412.3
  ENSP00000446153.2
  ENSP00000464721.1
  ENSP00000466622.1
  ENSP00000466629.1
  ENSP00000467781
  ENSP00000467781.1
  ENSP00000467922
  ENSP00000467922.1
  ENSP00000479191.1
GenBank Protein Q14587 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_694422   ⟸   NM_152943
- Peptide Label: isoform b
- UniProtKB: A0A075B6T9 (UniProtKB/TrEMBL),   E7EV44 (UniProtKB/TrEMBL),   H3BUM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_003406   ⟸   NM_003415
- Peptide Label: isoform a
- UniProtKB: Q96RH4 (UniProtKB/Swiss-Prot),   Q8TDG8 (UniProtKB/Swiss-Prot),   Q9BZJ9 (UniProtKB/Swiss-Prot),   Q14587 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001159357   ⟸   NM_001165885
- Peptide Label: isoform f
- UniProtKB: F5H7L3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001159355   ⟸   NM_001165883
- Peptide Label: isoform d
- UniProtKB: Q14587 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001159359   ⟸   NM_001165887
- Peptide Label: isoform h
- UniProtKB: K7EQP6 (UniProtKB/TrEMBL),   A0A087WV54 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001159358   ⟸   NM_001165886
- Peptide Label: isoform g
- UniProtKB: F5H670 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001159356   ⟸   NM_001165884
- Peptide Label: isoform e
- UniProtKB: F5H1T2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001159354   ⟸   NM_001165882
- Peptide Label: isoform c
- UniProtKB: Q2TB61 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001159353   ⟸   NM_001165881
- Peptide Label: isoform a
- UniProtKB: Q96RH4 (UniProtKB/Swiss-Prot),   Q8TDG8 (UniProtKB/Swiss-Prot),   Q9BZJ9 (UniProtKB/Swiss-Prot),   Q14587 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000442446   ⟸   ENST00000541211
RefSeq Acc Id: ENSP00000439539   ⟸   ENST00000541009
RefSeq Acc Id: ENSP00000446153   ⟸   ENST00000541975
RefSeq Acc Id: ENSP00000437858   ⟸   ENST00000542711
RefSeq Acc Id: ENSP00000443721   ⟸   ENST00000542986
RefSeq Acc Id: ENSP00000228289   ⟸   ENST00000228289
RefSeq Acc Id: ENSP00000437410   ⟸   ENST00000546126
RefSeq Acc Id: ENSP00000479191   ⟸   ENST00000611984
RefSeq Acc Id: ENSP00000409295   ⟸   ENST00000416488
RefSeq Acc Id: ENSP00000466622   ⟸   ENST00000588312
RefSeq Acc Id: ENSP00000438941   ⟸   ENST00000536899
RefSeq Acc Id: ENSP00000444412   ⟸   ENST00000536435
RefSeq Acc Id: ENSP00000467781   ⟸   ENST00000539248
RefSeq Acc Id: ENSP00000464721   ⟸   ENST00000591951
RefSeq Acc Id: ENSP00000467922   ⟸   ENST00000592241
RefSeq Acc Id: ENSP00000466629   ⟸   ENST00000500625
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q14587-F1-model_v2 AlphaFold Q14587 1-947 view protein structure

Promoters
RGD ID:6790167
Promoter ID:HG_KWN:17120
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000398413,   ENST00000405395,   NM_001165881,   NM_001165882,   NM_001165884,   NM_001165887,   NM_003415,   NM_152943,   UC001TDK.1,   UC001TYR.2,   UC001ULT.1,   UC009ZME.1,   UC009ZZD.1,   UC009ZZG.1,   UC009ZZH.1,   UC009ZZI.1
Position:
Human AssemblyChrPosition (strand)Source
Build 3612132,267,904 - 132,268,404 (+)MPROMDB
RGD ID:7225941
Promoter ID:EPDNEW_H18716
Type:initiation region
Name:ZNF268_1
Description:zinc finger protein 268
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812133,181,495 - 133,181,555EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:13061 AgrOrtholog
COSMIC ZNF268 COSMIC
Ensembl Genes ENSG00000090612 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000228289 ENTREZGENE
  ENST00000228289.9 UniProtKB/Swiss-Prot
  ENST00000416488.5 UniProtKB/TrEMBL
  ENST00000500625.7 UniProtKB/TrEMBL
  ENST00000536435 ENTREZGENE
  ENST00000536435.7 UniProtKB/Swiss-Prot
  ENST00000536899 ENTREZGENE
  ENST00000536899.6 UniProtKB/TrEMBL
  ENST00000539248 ENTREZGENE
  ENST00000539248.6 UniProtKB/Swiss-Prot
  ENST00000541009 ENTREZGENE
  ENST00000541009.6 UniProtKB/TrEMBL
  ENST00000541211 ENTREZGENE
  ENST00000541211.6 UniProtKB/TrEMBL
  ENST00000541975.2 UniProtKB/TrEMBL
  ENST00000542711 ENTREZGENE
  ENST00000542711.6 UniProtKB/TrEMBL
  ENST00000542986.6 UniProtKB/TrEMBL
  ENST00000546126.7 UniProtKB/TrEMBL
  ENST00000588312.2 UniProtKB/Swiss-Prot
  ENST00000591951.1 UniProtKB/TrEMBL
  ENST00000592241 ENTREZGENE
  ENST00000592241.5 UniProtKB/TrEMBL
  ENST00000611984.4 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000090612 GTEx
HGNC ID HGNC:13061 ENTREZGENE
Human Proteome Map ZNF268 Human Proteome Map
InterPro KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10795 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 10795 ENTREZGENE
OMIM 604753 OMIM
PANTHER KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/TrEMBL
  KRAB DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  NOVEL KRAB BOX AND ZINC FINGER, C2H2 TYPE DOMAIN CONTAINING PROTEIN-RELATED UniProtKB/TrEMBL
  ZINC FINGER AND BTB DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN 715 UniProtKB/Swiss-Prot
Pfam KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA37639 PharmGKB
PROSITE KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A075B6T9 ENTREZGENE, UniProtKB/TrEMBL
  A0A087WV54 ENTREZGENE, UniProtKB/TrEMBL
  E7EV44 ENTREZGENE, UniProtKB/TrEMBL
  F5H1T2 ENTREZGENE, UniProtKB/TrEMBL
  F5H467_HUMAN UniProtKB/TrEMBL
  F5H670 ENTREZGENE, UniProtKB/TrEMBL
  F5H6R9_HUMAN UniProtKB/TrEMBL
  F5H7L3 ENTREZGENE, UniProtKB/TrEMBL
  F5H848_HUMAN UniProtKB/TrEMBL
  H3BUM2 ENTREZGENE
  K7EIF0_HUMAN UniProtKB/TrEMBL
  K7EMS6_HUMAN UniProtKB/TrEMBL
  K7EQP6 ENTREZGENE, UniProtKB/TrEMBL
  Q14587 ENTREZGENE
  Q2TB61 ENTREZGENE, UniProtKB/TrEMBL
  Q8TDG8 ENTREZGENE
  Q96RH4 ENTREZGENE
  Q9BZJ9 ENTREZGENE
  ZN268_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary H3BUM2 UniProtKB/TrEMBL
  Q8TDG8 UniProtKB/Swiss-Prot
  Q96RH4 UniProtKB/Swiss-Prot
  Q9BZJ9 UniProtKB/Swiss-Prot