Zfp759 (zinc finger protein 759) - Rat Genome Database

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Gene: Zfp759 (zinc finger protein 759) Mus musculus
Analyze
No known orthologs.
Symbol: Zfp759
Name: zinc finger protein 759
RGD ID: 1617253
MGI Page MGI
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZNF845 (zinc finger protein 845).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BC028265; regulator of sex-limitation candidate 8; Rsl; Rslcan-8; Rslcan8
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391367,273,040 - 67,290,468 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1367,269,724 - 67,289,851 (+)EnsemblGRCm39 Ensembl
GRCm381367,121,659 - 67,142,404 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1367,121,660 - 67,141,787 (+)EnsemblGRCm38mm10GRCm38
MGSCv371367,229,164 - 67,242,723 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361367,627,352 - 67,640,884 (+)NCBIMGSCv36mm8
Celera1370,154,788 - 70,168,305 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1334.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14563677   PMID:15618518   PMID:15885501   PMID:16141072   PMID:16141073   PMID:20059953  
PMID:20412781   PMID:21677750   PMID:21873635  


Genomics

Variants

.
Variants in Zfp759
416 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:258
Count of miRNA genes:213
Interacting mature miRNAs:226
Transcripts:ENSMUST00000052716
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133492194368922081Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
26884396Humsd4_mhumerus midshaft diameter 4, 10 week (mouse)134785347673148119Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
1558850Sgp3_mserum gp70 production 3 (mouse)Not determined135647045676971314Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
10412163Wra1_mwheel running activity 1 (mouse)Not determined135913260093132738Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136425082198250945Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136425082198250945Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366744601100744746Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000052716   ⟹   ENSMUSP00000049650
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1367,276,292 - 67,289,851 (+)Ensembl
GRCm38.p6 Ensembl1367,128,228 - 67,141,787 (+)Ensembl
RefSeq Acc Id: ENSMUST00000224346   ⟹   ENSMUSP00000153653
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1367,269,724 - 67,286,806 (+)Ensembl
GRCm38.p6 Ensembl1367,121,660 - 67,138,742 (+)Ensembl
RefSeq Acc Id: ENSMUST00000224426
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1367,276,291 - 67,287,046 (+)Ensembl
GRCm38.p6 Ensembl1367,128,227 - 67,138,982 (+)Ensembl
RefSeq Acc Id: NM_172392   ⟹   NP_765980
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391367,276,292 - 67,289,851 (+)NCBI
GRCm381367,128,228 - 67,141,787 (+)NCBI
MGSCv371367,229,164 - 67,242,723 (+)RGD
Celera1370,154,788 - 70,168,305 (-)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006517253   ⟹   XP_006517316
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391367,273,200 - 67,290,468 (+)NCBI
GRCm381367,125,131 - 67,142,404 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030247272   ⟹   XP_030103132
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391367,273,090 - 67,290,468 (+)NCBI
GRCm381367,125,019 - 67,142,404 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030247274   ⟹   XP_030103134
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391367,273,040 - 67,290,468 (+)NCBI
GRCm381367,124,976 - 67,142,404 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_765980   ⟸   NM_172392
- UniProtKB: Q7M6X3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517316   ⟸   XM_006517253
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030103134   ⟸   XM_030247274
- Peptide Label: isoform X2
RefSeq Acc Id: XP_030103132   ⟸   XM_030247272
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000049650   ⟸   ENSMUST00000052716
RefSeq Acc Id: ENSMUSP00000153653   ⟸   ENSMUST00000224346
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7M6X3-F1-model_v2 AlphaFold Q7M6X3 1-721 view protein structure

Promoters
RGD ID:8680696
Promoter ID:EPDNEW_M18378
Type:initiation region
Name:Zfp759_1
Description:Mus musculus zinc finger protein 759 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381367,128,246 - 67,128,306EPDNEW
RGD ID:6824521
Promoter ID:MM_KWN:14552
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000052716
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361367,228,989 - 67,229,489 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2446280 AgrOrtholog
Ensembl Genes ENSMUSG00000057396 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000052716 ENTREZGENE
  ENSMUST00000052716.8 UniProtKB/TrEMBL
  ENSMUST00000224346.2 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB_dom_sf UniProtKB/TrEMBL
  Krueppel-associated_box UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report mmu:268670 UniProtKB/TrEMBL
MGD MGI:2446280 ENTREZGENE
NCBI Gene 268670 ENTREZGENE
PANTHER AA987161 PROTEIN-RELATED UniProtKB/TrEMBL
  GH23506P-RELATED UniProtKB/TrEMBL
  KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 589 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp759 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP Krueppel-associated_box UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A286YDZ7_MOUSE UniProtKB/TrEMBL
  Q7M6X3 ENTREZGENE, UniProtKB/TrEMBL
  Q8C0P2_MOUSE UniProtKB/TrEMBL
  Q8K167_MOUSE UniProtKB/TrEMBL