Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-alpha-phellandrene | increases expression | EXP | | 6480464 | alpha phellandrene results in increased expression of ZFP719 mRNA | CTD | PMID:25075043 | 1,2-dichloroethane | decreases expression | ISO | Zfp39 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of ZFP39 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | ISO | Zfp39 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ZFP39 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Zfp39 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ZFP39 mRNA | CTD | PMID:19933214 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Zfp39 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of ZFP39 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Zfp39 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ZFP39 mRNA | CTD | PMID:36041667 | 6-propyl-2-thiouracil | decreases expression | ISO | Zfp39 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of ZFP39 mRNA | CTD | PMID:30047161 | acrolein | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of ZNF717 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of ZNF717 mRNA | CTD | PMID:32699268 | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of ZNF717 gene | CTD | PMID:27153756 | Aflatoxin B2 alpha | decreases methylation | EXP | | 6480464 | aflatoxin B2 results in decreased methylation of ZNF717 promoter | CTD | PMID:30157460 | alpha-phellandrene | increases expression | EXP | | 6480464 | alpha phellandrene results in increased expression of ZFP719 mRNA | CTD | PMID:25075043 | alpha-pinene | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of ZNF717 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of ZNF717 mRNA | CTD | PMID:32699268 | amitrole | decreases expression | ISO | Zfp39 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of ZFP39 mRNA | CTD | PMID:30047161 | benzo[a]pyrene | increases expression | ISO | Zfp39 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ZFP39 mRNA | CTD | PMID:22228805 | bisphenol A | affects expression | ISO | Zfp39 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of ZFP39 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Zfp39 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ZFP39 mRNA | CTD | PMID:33221593 | bisphenol A | multiple interactions | ISO | Zfp39 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ZFP39 mRNA and [bisphenol A co-treated with Testosterone] results in decreased expression of ZFP39 mRNA | CTD | PMID:26496021 and PMID:36041667 | bisphenol F | multiple interactions | ISO | Zfp39 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ZFP39 mRNA | CTD | PMID:36041667 | butanal | increases expression | EXP | | 6480464 | butyraldehyde results in increased expression of ZNF717 mRNA | CTD | PMID:26079696 | diethylstilbestrol | decreases expression | ISO | Zfp39 (Rattus norvegicus) | 6480464 | Diethylstilbestrol results in decreased expression of ZFP39 mRNA | CTD | PMID:36653537 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | ethanol | affects splicing | ISO | Zfp39 (Mus musculus) | 6480464 | Ethanol affects the splicing of ZFP39 mRNA | CTD | PMID:30319688 | fenthion | decreases expression | ISO | Zfp39 (Mus musculus) | 6480464 | Fenthion results in decreased expression of ZFP39 mRNA | CTD | PMID:34813904 | mercury dibromide | decreases expression | EXP | | 6480464 | mercuric bromide results in decreased expression of ZNF717 mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZNF717 mRNA | CTD | PMID:27188386 | methimazole | decreases expression | ISO | Zfp39 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of ZFP39 mRNA | CTD | PMID:30047161 | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of ZNF717 mRNA | CTD | PMID:28001369 | ozone | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of ZNF717 mRNA more ... | CTD | PMID:32699268 | ozone | multiple interactions | ISO | Zfp39 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of ZFP39 mRNA | CTD | PMID:34911549 | pentanal | increases expression | EXP | | 6480464 | pentanal results in increased expression of ZNF717 mRNA | CTD | PMID:26079696 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of ZNF717 mRNA | CTD | PMID:36326898 | phenylmercury acetate | decreases expression | EXP | | 6480464 | Phenylmercuric Acetate results in decreased expression of ZNF717 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZNF717 mRNA | CTD | PMID:27188386 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Zfp39 (Rattus norvegicus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of ZFP39 mRNA | CTD | PMID:30047161 | propanal | increases expression | EXP | | 6480464 | propionaldehyde results in increased expression of ZNF717 mRNA | CTD | PMID:26079696 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of ZNF717 mRNA | CTD | PMID:29301061 | sulfadimethoxine | decreases expression | ISO | Zfp39 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of ZFP39 mRNA | CTD | PMID:30047161 | sunitinib | increases expression | EXP | | 6480464 | Sunitinib results in increased expression of ZNF717 mRNA | CTD | PMID:31533062 | testosterone | multiple interactions | ISO | Zfp39 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Testosterone] results in decreased expression of ZFP39 mRNA | CTD | PMID:26496021 | troglitazone | decreases expression | ISO | Zfp39 (Mus musculus) | 6480464 | troglitazone results in decreased expression of ZNF717 mRNA | CTD | PMID:28973697 | valproic acid | decreases methylation | EXP | | 6480464 | Valproic Acid results in decreased methylation of ZNF717 gene | CTD | PMID:29154799 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 |
Welcome {{ username}}
Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{gene.symbol}}: {{ gene.description }}
|
| You must be logged in to use this feature |
| {{ loginError }} |
|
|
Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
 |
Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
|
MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
|
||||||||||
Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Imported Human Phenotype Annotations - ClinVar
Gene-Chemical Interaction Annotations
Click to see Annotation Detail View
|
|
|
Gene Ontology Annotations
Click to see Annotation Detail View
Biological Process
|
|
Molecular Function
|
|
Phenotype Annotations
Click to see Annotation Detail View
References
References - curated
| # | Reference Title | Reference Citation |
| 1. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 2. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:12477932 | PMID:14702039 | PMID:16344560 | PMID:16641997 | PMID:21282530 | PMID:21873635 | PMID:29327728 | PMID:32665550 |
Genomics
Comparative Map Data
| ZNF717 (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Zfp39 (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Zfp39 (Rattus norvegicus - Norway rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| ZNF717 (Pan paniscus - bonobo/pygmy chimpanzee) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| LOC479758 (Canis lupus familiaris - dog) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| LOC100517161 (Sus scrofa - pig) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Variants
.
Variants in ZNF717
9 total Variants 
|
