Zfp87 (zinc finger protein 87) - Rat Genome Database

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Gene: Zfp87 (zinc finger protein 87) Mus musculus
Analyze
No known orthologs.
Symbol: Zfp87
Name: zinc finger protein 87
RGD ID: 1620651
MGI Page MGI
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including genitourinary system; lung; pharyngo-tympanic tube; retina nuclear layer; and thymus primordium. Orthologous to several human genes including ZNF28 (zinc finger protein 28); ZNF429 (zinc finger protein 429); and ZNF611 (zinc finger protein 611).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2210039O17Rik; 4631412O18Rik; KRA; KRAB zinc finger protein (Mzf22); KRAB4; MGC25780; Mzf22; Zfp7; Zfp72; zinc finger protein 72
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391367,663,900 - 67,674,350 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1367,663,900 - 67,674,296 (-)EnsemblGRCm39 Ensembl
GRCm381367,515,781 - 67,526,231 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1367,515,781 - 67,526,177 (-)EnsemblGRCm38mm10GRCm38
MGSCv371367,616,717 - 67,627,167 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361368,014,883 - 68,025,236 (-)NCBIMGSCv36mm8
Celera1369,781,639 - 69,792,088 (+)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1334.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2542606   PMID:7479878   PMID:8662221   PMID:8889548   PMID:10349636   PMID:10360839   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932  
PMID:12520002   PMID:14610273   PMID:15226823   PMID:15618518   PMID:16141072   PMID:16141073   PMID:18287559   PMID:18799693   PMID:20412781   PMID:21267068   PMID:21873635  


Genomics

Variants

.
Variants in Zfp87
372 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:597
Count of miRNA genes:389
Interacting mature miRNAs:426
Transcripts:ENSMUST00000180536, ENSMUST00000181341, ENSMUST00000181573, ENSMUST00000181767
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133492194368922081Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
26884396Humsd4_mhumerus midshaft diameter 4, 10 week (mouse)134785347673148119Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
1558850Sgp3_mserum gp70 production 3 (mouse)Not determined135647045676971314Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
10412163Wra1_mwheel running activity 1 (mouse)Not determined135913260093132738Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136425082198250945Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136425082198250945Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366744601100744746Mouse

Markers in Region
AA987161  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381367,589,681 - 67,589,800UniSTSGRCm38
MGSCv371367,690,618 - 67,690,737UniSTSGRCm37
Celera1369,715,862 - 69,715,981UniSTS
Cytogenetic Map13B3UniSTS
cM Map1343.0UniSTS
Whitehead/MRC_RH13652.35UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000180536   ⟹   ENSMUSP00000137812
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1367,665,695 - 67,674,240 (-)Ensembl
GRCm38.p6 Ensembl1367,517,576 - 67,526,121 (-)Ensembl
RefSeq Acc Id: ENSMUST00000181341   ⟹   ENSMUSP00000137689
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1367,666,100 - 67,674,265 (-)Ensembl
GRCm38.p6 Ensembl1367,517,981 - 67,526,146 (-)Ensembl
RefSeq Acc Id: ENSMUST00000181573   ⟹   ENSMUSP00000138011
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1367,669,158 - 67,674,296 (-)Ensembl
GRCm38.p6 Ensembl1367,521,039 - 67,526,177 (-)Ensembl
RefSeq Acc Id: ENSMUST00000181767   ⟹   ENSMUSP00000138087
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1367,663,900 - 67,674,296 (-)Ensembl
GRCm38.p6 Ensembl1367,515,781 - 67,526,177 (-)Ensembl
RefSeq Acc Id: NM_133228   ⟹   NP_573491
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391367,663,900 - 67,674,350 (-)NCBI
GRCm381367,515,781 - 67,526,231 (-)ENTREZGENE
MGSCv371367,616,717 - 67,627,167 (-)RGD
Celera1369,781,639 - 69,792,088 (+)RGD
cM Map13 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_573491   ⟸   NM_133228
- UniProtKB: Q8K2A4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000138087   ⟸   ENSMUST00000181767
RefSeq Acc Id: ENSMUSP00000137689   ⟸   ENSMUST00000181341
RefSeq Acc Id: ENSMUSP00000138011   ⟸   ENSMUST00000181573
RefSeq Acc Id: ENSMUSP00000137812   ⟸   ENSMUST00000180536
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K2A4-F1-model_v2 AlphaFold Q8K2A4 1-540 view protein structure

Promoters
RGD ID:6824543
Promoter ID:MM_KWN:14573
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_133228,   UC007RAZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361367,626,906 - 67,627,406 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107768 AgrOrtholog
Ensembl Genes ENSMUSG00000097333 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000180536.2 UniProtKB/TrEMBL
  ENSMUST00000181341.2 UniProtKB/TrEMBL
  ENSMUST00000181573.2 UniProtKB/TrEMBL
  ENSMUST00000181767 ENTREZGENE
  ENSMUST00000181767.8 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB_dom_sf UniProtKB/TrEMBL
  Krueppel-associated_box UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report mmu:170763 UniProtKB/TrEMBL
MGD MGI:107768 ENTREZGENE
NCBI Gene 170763 ENTREZGENE
PANTHER FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED UniProtKB/TrEMBL
  KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/TrEMBL
  KRAB DOMAIN-CONTAINING PROTEIN 5-RELATED UniProtKB/TrEMBL
  REDUCED EXPRESSION 2-RELATED UniProtKB/TrEMBL
  ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 200 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 52-RELATED UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 747 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 83 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp87 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP Krueppel-associated_box UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt M0QW75_MOUSE UniProtKB/TrEMBL
  M0QWG2_MOUSE UniProtKB/TrEMBL
  Q60914_MOUSE UniProtKB/TrEMBL
  Q8C1B9_MOUSE UniProtKB/TrEMBL
  Q8C1H3_MOUSE UniProtKB/TrEMBL
  Q8K2A4 ENTREZGENE, UniProtKB/TrEMBL
  Q9JIB9_MOUSE UniProtKB/TrEMBL