ZNF573 (zinc finger protein 573) - Rat Genome Database

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Gene: ZNF573 (zinc finger protein 573) Homo sapiens
Analyze
Symbol: ZNF573
Name: zinc finger protein 573
RGD ID: 1350499
HGNC Page HGNC:26420
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FLJ30921
RGD Orthologs
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381937,738,302 - 37,779,586 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1937,735,833 - 37,817,300 (-)EnsemblGRCh38hg38GRCh38
GRCh371938,229,203 - 38,270,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361942,921,028 - 42,962,040 (-)NCBINCBI36Build 36hg18NCBI36
Build 341942,921,042 - 42,962,040NCBI
Celera1935,029,744 - 35,070,573 (-)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1934,678,969 - 34,719,995 (-)NCBIHuRef
CHM1_11938,229,652 - 38,270,488 (-)NCBICHM1_1
T2T-CHM13v2.01940,540,059 - 40,581,107 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14702039   PMID:15342556   PMID:15489334   PMID:16344560   PMID:19322201   PMID:21873635   PMID:28065597   PMID:28514442   PMID:28986522   PMID:29507755   PMID:33961781   PMID:35563538  
PMID:36531074  


Genomics

Comparative Map Data
ZNF573
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381937,738,302 - 37,779,586 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1937,735,833 - 37,817,300 (-)EnsemblGRCh38hg38GRCh38
GRCh371938,229,203 - 38,270,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361942,921,028 - 42,962,040 (-)NCBINCBI36Build 36hg18NCBI36
Build 341942,921,042 - 42,962,040NCBI
Celera1935,029,744 - 35,070,573 (-)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1934,678,969 - 34,719,995 (-)NCBIHuRef
CHM1_11938,229,652 - 38,270,488 (-)NCBICHM1_1
T2T-CHM13v2.01940,540,059 - 40,581,107 (-)NCBIT2T-CHM13v2.0
Znf573
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554681,522,438 - 1,596,488 (-)NCBIChiLan1.0ChiLan1.0
ZNF573
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22043,856,540 - 43,944,860 (-)NCBINHGRI_mPanPan1-v2
LOC100686288
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11115,122,565 - 115,167,882 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1114,526,464 - 114,571,893 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01115,725,548 - 115,771,025 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11115,297,632 - 115,343,222 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01114,930,136 - 114,961,716 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01115,965,796 - 116,011,201 (-)NCBIUU_Cfam_GSD_1.0
Znf573
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934912,487,655 - 12,535,501 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936801671,134 - 693,069 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF573
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1632,400,722 - 32,446,421 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl632,400,948 - 32,425,668 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607310,337,388 - 10,387,059 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in ZNF573
30 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.12-13.2(chr19:37319377-42738688)x3 copy number gain See cases [RCV000050636] Chr19:37319377..42738688 [GRCh38]
Chr19:37810279..43242840 [GRCh37]
Chr19:42502119..47934680 [NCBI36]
Chr19:19q13.12-13.2		 pathogenic
NM_001172689.1(ZNF573):c.687T>C (p.Leu229=) single nucleotide variant Malignant melanoma [RCV000072115] Chr19:37739539 [GRCh38]
Chr19:38230440 [GRCh37]
Chr19:42922280 [NCBI36]
Chr19:19q13.12		 not provided
NM_001172689.1(ZNF573):c.202C>T (p.His68Tyr) single nucleotide variant Malignant melanoma [RCV000072116] Chr19:37740024 [GRCh38]
Chr19:38230925 [GRCh37]
Chr19:42922765 [NCBI36]
Chr19:19q13.12		 not provided
GRCh38/hg38 19p13.2-q13.31(chr19:11227942-44626354)x3 copy number gain See cases [RCV000133888] Chr19:11227942..44626354 [GRCh38]
Chr19:11338618..45129651 [GRCh37]
Chr19:11199618..49821491 [NCBI36]
Chr19:19p13.2-q13.31		 pathogenic
GRCh38/hg38 19q12-13.13(chr19:29661858-38114723)x1 copy number loss See cases [RCV000135879] Chr19:29661858..38114723 [GRCh38]
Chr19:30152765..38605363 [GRCh37]
Chr19:34844605..43297203 [NCBI36]
Chr19:19q12-13.13		 pathogenic
GRCh38/hg38 19q12-13.13(chr19:29671324-37902990)x1 copy number loss See cases [RCV000136794] Chr19:29671324..37902990 [GRCh38]
Chr19:30162231..38393630 [GRCh37]
Chr19:34854071..43085470 [NCBI36]
Chr19:19q12-13.13		 pathogenic
GRCh37/hg19 19q13.12-13.2(chr19:37582250-41630908)x3 copy number gain See cases [RCV000239839] Chr19:37582250..41630908 [GRCh37]
Chr19:19q13.12-13.2		 pathogenic
GRCh37/hg19 19q13.12-13.2(chr19:36685995-38708166)x1 copy number loss Breast ductal adenocarcinoma [RCV000207200] Chr19:36685995..38708166 [GRCh37]
Chr19:19q13.12-13.2		 uncertain significance
chr19:36674305-38652962 complex variant complex Breast ductal adenocarcinoma [RCV000207036] Chr19:36674305..38652962 [GRCh37]
Chr19:19q13.12-13.13		 uncertain significance
GRCh37/hg19 19q13.12-13.13(chr19:36475577-38399402)x3 copy number gain See cases [RCV000240597] Chr19:36475577..38399402 [GRCh37]
Chr19:19q13.12-13.13		 uncertain significance
GRCh37/hg19 19q13.12(chr19:38189585-38241015)x1 copy number loss not provided [RCV000752676] Chr19:38189585..38241015 [GRCh37]
Chr19:19q13.12		 benign
GRCh37/hg19 19q13.12-13.13(chr19:38219241-38397213)x1 copy number loss not provided [RCV000752677] Chr19:38219241..38397213 [GRCh37]
Chr19:19q13.12-13.13		 benign
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
NM_001172690.2(ZNF573):c.1844G>T (p.Cys615Phe) single nucleotide variant not specified [RCV004319674] Chr19:37738646 [GRCh38]
Chr19:38229547 [GRCh37]
Chr19:19q13.12		 uncertain significance
GRCh37/hg19 19q13.12-13.13(chr19:38203613-38575729)x1 copy number loss not provided [RCV001007046] Chr19:38203613..38575729 [GRCh37]
Chr19:19q13.12-13.13		 uncertain significance
NM_001172690.2(ZNF573):c.1073A>G (p.Tyr358Cys) single nucleotide variant not specified [RCV004314581] Chr19:37739417 [GRCh38]
Chr19:38230318 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1258G>A (p.Gly420Arg) single nucleotide variant not specified [RCV004302185] Chr19:37739232 [GRCh38]
Chr19:38230133 [GRCh37]
Chr19:19q13.12		 uncertain significance
GRCh37/hg19 19q11-13.33(chr19:28271106-49213832)x3 copy number gain not provided [RCV000845733] Chr19:28271106..49213832 [GRCh37]
Chr19:19q11-13.33		 pathogenic
NM_001172690.2(ZNF573):c.1693C>T (p.Arg565Cys) single nucleotide variant not specified [RCV004313636] Chr19:37738797 [GRCh38]
Chr19:38229698 [GRCh37]
Chr19:19q13.12		 uncertain significance
GRCh37/hg19 19q13.12-13.13(chr19:38243156-38570829)x3 copy number gain not provided [RCV001259939] Chr19:38243156..38570829 [GRCh37]
Chr19:19q13.12-13.13		 uncertain significance
GRCh37/hg19 19p13.11-q13.2(chr19:19546923-41313229)x3 copy number gain Specific learning disability [RCV001801194] Chr19:19546923..41313229 [GRCh37]
Chr19:19p13.11-q13.2		 pathogenic
GRCh37/hg19 19q13.12-13.13(chr19:37389799-38562489)x3 copy number gain not provided [RCV002472711] Chr19:37389799..38562489 [GRCh37]
Chr19:19q13.12-13.13		 uncertain significance
NM_001172690.2(ZNF573):c.1462C>T (p.His488Tyr) single nucleotide variant not specified [RCV004242521] Chr19:37739028 [GRCh38]
Chr19:38229929 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.806C>G (p.Thr269Ser) single nucleotide variant not specified [RCV004109082] Chr19:37739684 [GRCh38]
Chr19:38230585 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.388A>G (p.Arg130Gly) single nucleotide variant not specified [RCV004210732] Chr19:37740102 [GRCh38]
Chr19:38231003 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1174G>C (p.Gly392Arg) single nucleotide variant not specified [RCV004164678] Chr19:37739316 [GRCh38]
Chr19:38230217 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1157T>C (p.Phe386Ser) single nucleotide variant not specified [RCV004191902] Chr19:37739333 [GRCh38]
Chr19:38230234 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1579G>C (p.Glu527Gln) single nucleotide variant not specified [RCV004125403] Chr19:37738911 [GRCh38]
Chr19:38229812 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.608A>G (p.Tyr203Cys) single nucleotide variant not specified [RCV004236429] Chr19:37739882 [GRCh38]
Chr19:38230783 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.734C>T (p.Pro245Leu) single nucleotide variant not specified [RCV004140133] Chr19:37739756 [GRCh38]
Chr19:38230657 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.696C>A (p.His232Gln) single nucleotide variant not specified [RCV004214811] Chr19:37739794 [GRCh38]
Chr19:38230695 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1719G>C (p.Gln573His) single nucleotide variant not specified [RCV004089115] Chr19:37738771 [GRCh38]
Chr19:38229672 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1310C>T (p.Thr437Ile) single nucleotide variant not specified [RCV004162221] Chr19:37739180 [GRCh38]
Chr19:38230081 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.648A>T (p.Lys216Asn) single nucleotide variant not specified [RCV004195592] Chr19:37739842 [GRCh38]
Chr19:38230743 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1702C>T (p.His568Tyr) single nucleotide variant not specified [RCV004129524] Chr19:37738788 [GRCh38]
Chr19:38229689 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.209A>G (p.His70Arg) single nucleotide variant not specified [RCV004135100] Chr19:37770091 [GRCh38]
Chr19:38260731 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1366A>G (p.Asn456Asp) single nucleotide variant not specified [RCV004077322] Chr19:37739124 [GRCh38]
Chr19:38230025 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1078T>C (p.Cys360Arg) single nucleotide variant not specified [RCV004290269] Chr19:37739412 [GRCh38]
Chr19:38230313 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1529A>G (p.His510Arg) single nucleotide variant not specified [RCV004297603] Chr19:37738961 [GRCh38]
Chr19:38229862 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.41G>T (p.Arg14Met) single nucleotide variant not specified [RCV004284993] Chr19:37773689 [GRCh38]
Chr19:38264329 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1463A>G (p.His488Arg) single nucleotide variant not specified [RCV004248450] Chr19:37739027 [GRCh38]
Chr19:38229928 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1377A>G (p.Arg459=) single nucleotide variant not provided [RCV003425123] Chr19:37739113 [GRCh38]
Chr19:38230014 [GRCh37]
Chr19:19q13.12		 likely benign
NM_001172690.2(ZNF573):c.1164C>T (p.Cys388=) single nucleotide variant not provided [RCV003425124] Chr19:37739326 [GRCh38]
Chr19:38230227 [GRCh37]
Chr19:19q13.12		 likely benign
NM_001172690.2(ZNF573):c.1392C>T (p.His464=) single nucleotide variant not provided [RCV003406948] Chr19:37739098 [GRCh38]
Chr19:38229999 [GRCh37]
Chr19:19q13.12		 likely benign
GRCh37/hg19 19q11-13.2(chr19:28271146-41508851)x3 copy number gain not specified [RCV003986115] Chr19:28271146..41508851 [GRCh37]
Chr19:19q11-13.2		 pathogenic
NM_001172690.2(ZNF573):c.1466G>A (p.Arg489Gln) single nucleotide variant not specified [RCV004494709] Chr19:37739024 [GRCh38]
Chr19:38229925 [GRCh37]
Chr19:19q13.12		 likely benign
NM_001172690.2(ZNF573):c.1568T>C (p.Met523Thr) single nucleotide variant not specified [RCV004494710] Chr19:37738922 [GRCh38]
Chr19:38229823 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1745A>G (p.Tyr582Cys) single nucleotide variant not specified [RCV004494712] Chr19:37738745 [GRCh38]
Chr19:38229646 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1816G>T (p.Gly606Cys) single nucleotide variant not specified [RCV004494713] Chr19:37738674 [GRCh38]
Chr19:38229575 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1871A>G (p.Asn624Ser) single nucleotide variant not specified [RCV004494714] Chr19:37738619 [GRCh38]
Chr19:38229520 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.310T>C (p.Cys104Arg) single nucleotide variant not specified [RCV004494715] Chr19:37740180 [GRCh38]
Chr19:38231081 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.313G>A (p.Glu105Lys) single nucleotide variant not specified [RCV004494716] Chr19:37740177 [GRCh38]
Chr19:38231078 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.653A>G (p.Tyr218Cys) single nucleotide variant not specified [RCV004494718] Chr19:37739837 [GRCh38]
Chr19:38230738 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.685T>C (p.Tyr229His) single nucleotide variant not specified [RCV004494719] Chr19:37739805 [GRCh38]
Chr19:38230706 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.686A>G (p.Tyr229Cys) single nucleotide variant not specified [RCV004494720] Chr19:37739804 [GRCh38]
Chr19:38230705 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1667G>A (p.Cys556Tyr) single nucleotide variant not specified [RCV004494711] Chr19:37738823 [GRCh38]
Chr19:38229724 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.383A>G (p.Tyr128Cys) single nucleotide variant not specified [RCV004494717] Chr19:37740107 [GRCh38]
Chr19:38231008 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.1115A>C (p.Asn372Thr) single nucleotide variant not specified [RCV004494708] Chr19:37739375 [GRCh38]
Chr19:38230276 [GRCh37]
Chr19:19q13.12		 uncertain significance
NM_001172690.2(ZNF573):c.82G>A (p.Val28Met) single nucleotide variant not specified [RCV004494722] Chr19:37771684 [GRCh38]
Chr19:38262324 [GRCh37]
Chr19:19q13.12		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3831
Count of miRNA genes:1056
Interacting mature miRNAs:1262
Transcripts:ENST00000339503, ENST00000357309, ENST00000378445, ENST00000392138, ENST00000480587, ENST00000489148, ENST00000494605, ENST00000536220, ENST00000585724, ENST00000586155, ENST00000586785, ENST00000587684, ENST00000588218, ENST00000588443, ENST00000589435, ENST00000589632, ENST00000590414, ENST00000590674, ENST00000591516
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
G59778  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371938,229,346 - 38,229,473UniSTSGRCh37
Build 361942,921,186 - 42,921,313RGDNCBI36
Celera1935,029,887 - 35,030,014RGD
Cytogenetic Map19q13.12UniSTS
HuRef1934,679,112 - 34,679,239UniSTS
TNG Radiation Hybrid Map1914113.0UniSTS
WIAF-2206  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371938,229,346 - 38,229,473UniSTSGRCh37
Build 361942,921,186 - 42,921,313RGDNCBI36
Celera1935,029,887 - 35,030,014RGD
Cytogenetic Map19q13.12UniSTS
HuRef1934,679,112 - 34,679,239UniSTS
GeneMap99-GB4 RH Map19219.35UniSTS
D22S1584  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map16p13.13UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map5q31.3UniSTS
Cytogenetic Map22q11.2UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map2q33-q34UniSTS
Cytogenetic Map19q13.1-q13.2UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map2q32-q34UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map10p15-p14UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map5q33.1UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map10q24.2UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1 4 28 1 10 1 12 2
Low 2051 1758 1378 324 1042 174 3829 1389 2237 313 1392 1527 164 1 1066 2339 5 2
Below cutoff 384 1212 344 300 851 291 526 806 1487 104 55 80 9 138 449

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001172689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001172690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001172691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001172692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_152360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC016582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC093227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK055483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK074539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC042170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC064962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG572864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP274132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA778380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB121870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF510455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OP680444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000339503   ⟹   ENSP00000340171
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,738,302 - 37,758,596 (-)Ensembl
RefSeq Acc Id: ENST00000357309   ⟹   ENSP00000349861
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,738,302 - 37,779,590 (-)Ensembl
RefSeq Acc Id: ENST00000378445   ⟹   ENSP00000367706
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,740,061 - 37,779,574 (-)Ensembl
RefSeq Acc Id: ENST00000392138   ⟹   ENSP00000375983
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,738,302 - 37,817,300 (-)Ensembl
RefSeq Acc Id: ENST00000480587
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,792,570 - 37,817,221 (-)Ensembl
RefSeq Acc Id: ENST00000489148   ⟹   ENSP00000465857
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,739,906 - 37,773,745 (-)Ensembl
RefSeq Acc Id: ENST00000494605
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,770,407 - 37,779,878 (-)Ensembl
RefSeq Acc Id: ENST00000536220   ⟹   ENSP00000440464
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,738,302 - 37,779,586 (-)Ensembl
RefSeq Acc Id: ENST00000585724   ⟹   ENSP00000466356
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,739,946 - 37,779,563 (-)Ensembl
RefSeq Acc Id: ENST00000586155   ⟹   ENSP00000465148
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,738,302 - 37,779,585 (-)Ensembl
RefSeq Acc Id: ENST00000586785
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,793,630 - 37,817,259 (-)Ensembl
RefSeq Acc Id: ENST00000587684
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,793,433 - 37,817,261 (-)Ensembl
RefSeq Acc Id: ENST00000588218   ⟹   ENSP00000468391
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,770,039 - 37,779,583 (-)Ensembl
RefSeq Acc Id: ENST00000588443
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,793,976 - 37,817,292 (-)Ensembl
RefSeq Acc Id: ENST00000589435
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,794,035 - 37,817,270 (-)Ensembl
RefSeq Acc Id: ENST00000589632   ⟹   ENSP00000467929
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,738,287 - 37,779,560 (-)Ensembl
RefSeq Acc Id: ENST00000590414   ⟹   ENSP00000465020
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,738,287 - 37,773,751 (-)Ensembl
RefSeq Acc Id: ENST00000590674
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,735,833 - 37,740,138 (-)Ensembl
RefSeq Acc Id: ENST00000591516   ⟹   ENSP00000466316
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1937,740,084 - 37,779,553 (-)Ensembl
RefSeq Acc Id: NM_001172689   ⟹   NP_001166160
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381937,738,302 - 37,779,586 (-)NCBI
GRCh371938,229,203 - 38,270,230 (-)RGD
Celera1935,029,744 - 35,070,573 (-)RGD
HuRef1934,678,969 - 34,719,995 (-)RGD
CHM1_11938,229,652 - 38,270,488 (-)NCBI
T2T-CHM13v2.01940,540,059 - 40,581,107 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001172690   ⟹   NP_001166161
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381937,738,302 - 37,779,586 (-)NCBI
GRCh371938,229,203 - 38,270,230 (-)RGD
Celera1935,029,744 - 35,070,573 (-)RGD
HuRef1934,678,969 - 34,719,995 (-)RGD
CHM1_11938,229,652 - 38,270,488 (-)NCBI
T2T-CHM13v2.01940,540,059 - 40,581,107 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001172691   ⟹   NP_001166162
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381937,738,302 - 37,779,586 (-)NCBI
GRCh371938,229,203 - 38,270,230 (-)RGD
Celera1935,029,744 - 35,070,573 (-)RGD
HuRef1934,678,969 - 34,719,995 (-)RGD
CHM1_11938,229,652 - 38,270,488 (-)NCBI
T2T-CHM13v2.01940,540,059 - 40,581,107 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001172692   ⟹   NP_001166163
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381937,738,302 - 37,779,586 (-)NCBI
GRCh371938,229,203 - 38,270,230 (-)RGD
Celera1935,029,744 - 35,070,573 (-)RGD
HuRef1934,678,969 - 34,719,995 (-)RGD
CHM1_11938,229,652 - 38,270,488 (-)NCBI
T2T-CHM13v2.01940,540,059 - 40,581,107 (-)NCBI
Sequence:
RefSeq Acc Id: NM_152360   ⟹   NP_689573
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381937,738,302 - 37,779,586 (-)NCBI
GRCh371938,229,203 - 38,270,230 (-)RGD
Build 361942,921,028 - 42,962,040 (-)NCBI Archive
Celera1935,029,744 - 35,070,573 (-)RGD
HuRef1934,678,969 - 34,719,995 (-)RGD
CHM1_11938,229,652 - 38,270,488 (-)NCBI
T2T-CHM13v2.01940,540,059 - 40,581,107 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_689573   ⟸   NM_152360
- Peptide Label: isoform 1
- UniProtKB: Q86YE8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001166160   ⟸   NM_001172689
- Peptide Label: isoform 2
- UniProtKB: Q86YE8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001166161   ⟸   NM_001172690
- Peptide Label: isoform 3
- UniProtKB: Q96BM3 (UniProtKB/Swiss-Prot),   Q8N2Q1 (UniProtKB/Swiss-Prot),   Q7Z7Q3 (UniProtKB/Swiss-Prot),   Q6P1P1 (UniProtKB/Swiss-Prot),   K7EJ45 (UniProtKB/Swiss-Prot),   B7WPE1 (UniProtKB/Swiss-Prot),   Q96NH0 (UniProtKB/Swiss-Prot),   Q86YE8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001166162   ⟸   NM_001172691
- Peptide Label: isoform 4
- UniProtKB: Q86YE8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001166163   ⟸   NM_001172692
- Peptide Label: isoform 2
- UniProtKB: Q86YE8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000466356   ⟸   ENST00000585724
RefSeq Acc Id: ENSP00000465148   ⟸   ENST00000586155
RefSeq Acc Id: ENSP00000468391   ⟸   ENST00000588218
RefSeq Acc Id: ENSP00000367706   ⟸   ENST00000378445
RefSeq Acc Id: ENSP00000467929   ⟸   ENST00000589632
RefSeq Acc Id: ENSP00000340171   ⟸   ENST00000339503
RefSeq Acc Id: ENSP00000440464   ⟸   ENST00000536220
RefSeq Acc Id: ENSP00000375983   ⟸   ENST00000392138
RefSeq Acc Id: ENSP00000465020   ⟸   ENST00000590414
RefSeq Acc Id: ENSP00000466316   ⟸   ENST00000591516
RefSeq Acc Id: ENSP00000349861   ⟸   ENST00000357309
RefSeq Acc Id: ENSP00000465857   ⟸   ENST00000489148
Protein Domains
KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q86YE8-F1-model_v2 AlphaFold Q86YE8 1-665 view protein structure

Promoters
RGD ID:7239767
Promoter ID:EPDNEW_H25629
Type:multiple initiation site
Name:ZNF573_1
Description:zinc finger protein 573
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381937,779,586 - 37,779,646EPDNEW
RGD ID:6796367
Promoter ID:HG_KWN:29806
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001172690,   NM_001172691,   NM_001172692,   OTTHUMT00000109612,   OTTHUMT00000109614,   UC002OHF.1,   UC002OHG.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361942,961,901 - 42,962,401 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:26420 AgrOrtholog
COSMIC ZNF573 COSMIC
Ensembl Genes ENSG00000189144 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000339503 ENTREZGENE
  ENST00000339503.7 UniProtKB/Swiss-Prot
  ENST00000378445.8 UniProtKB/TrEMBL
  ENST00000392138.5 UniProtKB/Swiss-Prot
  ENST00000489148.5 UniProtKB/TrEMBL
  ENST00000536220 ENTREZGENE
  ENST00000536220.7 UniProtKB/Swiss-Prot
  ENST00000585724.5 UniProtKB/TrEMBL
  ENST00000586155.5 UniProtKB/TrEMBL
  ENST00000588218.1 UniProtKB/TrEMBL
  ENST00000589632.5 UniProtKB/TrEMBL
  ENST00000591516.6 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/Swiss-Prot
GTEx ENSG00000189144 GTEx
HGNC ID HGNC:26420 ENTREZGENE
Human Proteome Map ZNF573 Human Proteome Map
InterPro KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report hsa:126231 UniProtKB/Swiss-Prot
NCBI Gene 126231 ENTREZGENE
PANTHER KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/TrEMBL
  KRAB DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN 529 UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN 726 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/Swiss-Prot
  zf-C2H2_6 UniProtKB/Swiss-Prot
PharmGKB PA134883623 PharmGKB
PRINTS F138DOMAIN UniProtKB/TrEMBL
PROSITE KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF109640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57667 UniProtKB/Swiss-Prot
UniProt A0A0A0MRV5_HUMAN UniProtKB/TrEMBL
  B7WPE1 ENTREZGENE
  K7EJ45 ENTREZGENE
  K7EL03_HUMAN UniProtKB/TrEMBL
  K7EM14_HUMAN UniProtKB/TrEMBL
  K7EM47_HUMAN UniProtKB/TrEMBL
  K7EQQ2_HUMAN UniProtKB/TrEMBL
  K7ERS7_HUMAN UniProtKB/TrEMBL
  Q6P1P1 ENTREZGENE
  Q6PIT4_HUMAN UniProtKB/TrEMBL
  Q7Z7Q3 ENTREZGENE
  Q86YE8 ENTREZGENE
  Q8N2Q1 ENTREZGENE
  Q96BM3 ENTREZGENE
  Q96NH0 ENTREZGENE
  ZN573_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B7WPE1 UniProtKB/Swiss-Prot
  K7EJ45 UniProtKB/Swiss-Prot
  Q6P1P1 UniProtKB/Swiss-Prot
  Q7Z7Q3 UniProtKB/Swiss-Prot
  Q8N2Q1 UniProtKB/Swiss-Prot
  Q96BM3 UniProtKB/Swiss-Prot
  Q96NH0 UniProtKB/Swiss-Prot