ZNF136 (zinc finger protein 136) - Rat Genome Database

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Gene: ZNF136 (zinc finger protein 136) Homo sapiens
Analyze
Symbol: ZNF136
Name: zinc finger protein 136
RGD ID: 1345728
HGNC Page HGNC:12920
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: pHZ-20
RGD Orthologs
Bonobo
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381912,163,096 - 12,189,871 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1912,163,064 - 12,189,871 (+)EnsemblGRCh38hg38GRCh38
GRCh371912,273,911 - 12,300,686 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,134,919 - 12,161,064 (+)NCBINCBI36Build 36hg18NCBI36
Build 341912,134,918 - 12,161,063NCBI
Celera1912,186,369 - 12,194,643 (+)NCBICelera
Cytogenetic Map19p13.2ENTREZGENE
HuRef1911,848,917 - 11,875,108 (+)NCBIHuRef
CHM1_11912,273,699 - 12,299,875 (+)NCBICHM1_1
T2T-CHM13v2.01912,287,953 - 12,318,112 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IEA)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7557990   PMID:7649249   PMID:7865130   PMID:12477932   PMID:14702039   PMID:15146197   PMID:15489334   PMID:16189514   PMID:16344560   PMID:19060904   PMID:19156129   PMID:21516116  
PMID:21873635   PMID:24136724   PMID:25416956   PMID:28514442   PMID:29395067   PMID:31515488   PMID:31586073   PMID:32296183   PMID:32891193   PMID:33961781   PMID:34079125   PMID:35563538  
PMID:36089195  


Genomics

Comparative Map Data
ZNF136
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381912,163,096 - 12,189,871 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1912,163,064 - 12,189,871 (+)EnsemblGRCh38hg38GRCh38
GRCh371912,273,911 - 12,300,686 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,134,919 - 12,161,064 (+)NCBINCBI36Build 36hg18NCBI36
Build 341912,134,918 - 12,161,063NCBI
Celera1912,186,369 - 12,194,643 (+)NCBICelera
Cytogenetic Map19p13.2ENTREZGENE
HuRef1911,848,917 - 11,875,108 (+)NCBIHuRef
CHM1_11912,273,699 - 12,299,875 (+)NCBICHM1_1
T2T-CHM13v2.01912,287,953 - 12,318,112 (+)NCBIT2T-CHM13v2.0
ZNF136
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22017,086,475 - 17,158,576 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11916,086,746 - 16,158,865 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01911,752,504 - 11,796,167 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11912,521,913 - 12,536,570 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1912,490,274 - 12,516,458 (+)NCBIpanpan1.1panPan2
PanPan1.1 Ensembl1912,490,274 - 12,516,458 (+)Ensemblpanpan1.1panPan2
ZNF136
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1610,984,818 - 11,012,092 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660748,804,335 - 8,834,093 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in ZNF136
30 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19p13.2-13.13(chr19:8831147-13331227)x3 copy number gain See cases [RCV000052908] Chr19:8831147..13331227 [GRCh38]
Chr19:8941823..13442041 [GRCh37]
Chr19:8802823..13303041 [NCBI36]
Chr19:19p13.2-13.13		 likely pathogenic
GRCh38/hg38 19p13.2-13.12(chr19:10315258-14048994)x3 copy number gain See cases [RCV000052909] Chr19:10315258..14048994 [GRCh38]
Chr19:10425934..14159806 [GRCh37]
Chr19:10286934..14020806 [NCBI36]
Chr19:19p13.2-13.12		 pathogenic
GRCh38/hg38 19p13.2-13.12(chr19:12132052-14751798)x3 copy number gain See cases [RCV000052910] Chr19:12132052..14751798 [GRCh38]
Chr19:12242867..14862610 [GRCh37]
Chr19:12103867..14723610 [NCBI36]
Chr19:19p13.2-13.12		 pathogenic
GRCh38/hg38 19p13.2-13.12(chr19:11227942-14532135)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053944]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053944]|See cases [RCV000053944] Chr19:11227942..14532135 [GRCh38]
Chr19:11338618..14642947 [GRCh37]
Chr19:11199618..14503947 [NCBI36]
Chr19:19p13.2-13.12		 pathogenic
GRCh38/hg38 19p13.2-13.13(chr19:11517825-13225287)x1 copy number loss See cases [RCV000053945] Chr19:11517825..13225287 [GRCh38]
Chr19:11628640..13336101 [GRCh37]
Chr19:11489640..13197101 [NCBI36]
Chr19:19p13.2-13.13		 pathogenic
NM_003437.5(ZNF136):c.883T>G (p.Leu295Val) single nucleotide variant Malignant tumor of prostate [RCV000149150] Chr19:12187261 [GRCh38]
Chr19:12298076 [GRCh37]
Chr19:19p13.2		 uncertain significance
GRCh38/hg38 19p13.2-q13.31(chr19:11227942-44626354)x3 copy number gain See cases [RCV000133888] Chr19:11227942..44626354 [GRCh38]
Chr19:11338618..45129651 [GRCh37]
Chr19:11199618..49821491 [NCBI36]
Chr19:19p13.2-q13.31		 pathogenic
GRCh38/hg38 19p13.2-13.12(chr19:11525163-14155021)x1 copy number loss See cases [RCV000136909] Chr19:11525163..14155021 [GRCh38]
Chr19:11635978..14265833 [GRCh37]
Chr19:11496978..14126833 [NCBI36]
Chr19:19p13.2-13.12		 pathogenic
GRCh38/hg38 19p13.2-13.13(chr19:10319474-13777860)x1 copy number loss See cases [RCV000141568] Chr19:10319474..13777860 [GRCh38]
Chr19:10430150..13888674 [GRCh37]
Chr19:10291150..13749674 [NCBI36]
Chr19:19p13.2-13.13		 pathogenic
GRCh37/hg19 19p13.2(chr19:12204632-13497073)x1 copy number loss See cases [RCV000449161] Chr19:12204632..13497073 [GRCh37]
Chr19:19p13.2		 pathogenic
GRCh37/hg19 19p13.2-13.12(chr19:9678768-14853426) copy number gain See cases [RCV000446985] Chr19:9678768..14853426 [GRCh37]
Chr19:19p13.2-13.12		 pathogenic
GRCh37/hg19 19p13.2-13.12(chr19:11608072-14543046)x3 copy number gain See cases [RCV000511013] Chr19:11608072..14543046 [GRCh37]
Chr19:19p13.2-13.12		 uncertain significance
NM_003437.5(ZNF136):c.55G>T (p.Ala19Ser) single nucleotide variant not specified [RCV004314921] Chr19:12185836 [GRCh38]
Chr19:12296651 [GRCh37]
Chr19:19p13.2		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
Single allele deletion not provided [RCV000844961] Chr19:10642984..12810067 [GRCh37]
Chr19:19p13.2		 not provided
NC_000019.9:g.(?_11277234)_(13249220_?)dup duplication not provided [RCV003105511] Chr19:11277234..13249220 [GRCh37]
Chr19:19p13.2		 uncertain significance
GRCh37/hg19 19p13.2(chr19:10642984-12810067) copy number loss not provided [RCV001249213] Chr19:10642984..12810067 [GRCh37]
Chr19:19p13.2		 not provided
NC_000019.9:g.(?_10828919)_(13482613_?)dup duplication Charcot-Marie-Tooth disease dominant intermediate B [RCV003109233]|Deficiency of alpha-mannosidase [RCV003109232]|Episodic ataxia type 2 [RCV003109234]|Glutaric aciduria, type 1 [RCV003122092] Chr19:10828919..13482613 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.1136T>C (p.Met379Thr) single nucleotide variant not specified [RCV004309363] Chr19:12187514 [GRCh38]
Chr19:12298329 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.1148T>C (p.Met383Thr) single nucleotide variant not specified [RCV004144144] Chr19:12187526 [GRCh38]
Chr19:12298341 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.1269A>C (p.Lys423Asn) single nucleotide variant not specified [RCV004107670] Chr19:12187647 [GRCh38]
Chr19:12298462 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.701C>G (p.Thr234Ser) single nucleotide variant not specified [RCV004137714] Chr19:12187079 [GRCh38]
Chr19:12297894 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.176G>A (p.Arg59Gln) single nucleotide variant not specified [RCV004222908] Chr19:12186159 [GRCh38]
Chr19:12296974 [GRCh37]
Chr19:19p13.2		 likely benign
NM_003437.5(ZNF136):c.136A>G (p.Lys46Glu) single nucleotide variant not specified [RCV004165442] Chr19:12186119 [GRCh38]
Chr19:12296934 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.1046G>T (p.Ser349Ile) single nucleotide variant not specified [RCV004104142] Chr19:12187424 [GRCh38]
Chr19:12298239 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.377G>T (p.Gly126Val) single nucleotide variant not specified [RCV004103247] Chr19:12186755 [GRCh38]
Chr19:12297570 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.1276G>A (p.Gly426Ser) single nucleotide variant not specified [RCV004092674] Chr19:12187654 [GRCh38]
Chr19:12298469 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.973C>G (p.Leu325Val) single nucleotide variant not specified [RCV004104143] Chr19:12187351 [GRCh38]
Chr19:12298166 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.1322C>G (p.Thr441Ser) single nucleotide variant not specified [RCV004084257] Chr19:12187700 [GRCh38]
Chr19:12298515 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.1133G>C (p.Ser378Thr) single nucleotide variant not specified [RCV004157710] Chr19:12187511 [GRCh38]
Chr19:12298326 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.1004C>T (p.Pro335Leu) single nucleotide variant not specified [RCV004194878] Chr19:12187382 [GRCh38]
Chr19:12298197 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.125C>G (p.Ser42Cys) single nucleotide variant not specified [RCV004136973] Chr19:12185906 [GRCh38]
Chr19:12296721 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.368A>G (p.Asp123Gly) single nucleotide variant not specified [RCV004117504] Chr19:12186746 [GRCh38]
Chr19:12297561 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.300A>C (p.Lys100Asn) single nucleotide variant not specified [RCV004226885] Chr19:12186678 [GRCh38]
Chr19:12297493 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.199A>G (p.Met67Val) single nucleotide variant not specified [RCV004217555] Chr19:12186577 [GRCh38]
Chr19:12297392 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.719G>A (p.Arg240Gln) single nucleotide variant not specified [RCV004270162] Chr19:12187097 [GRCh38]
Chr19:12297912 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.1062T>G (p.His354Gln) single nucleotide variant not specified [RCV004280866] Chr19:12187440 [GRCh38]
Chr19:12298255 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.1105T>G (p.Cys369Gly) single nucleotide variant not specified [RCV004264046] Chr19:12187483 [GRCh38]
Chr19:12298298 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.19G>A (p.Glu7Lys) single nucleotide variant not specified [RCV004272252] Chr19:12185800 [GRCh38]
Chr19:12296615 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.499C>T (p.Leu167Phe) single nucleotide variant not specified [RCV004300047] Chr19:12186877 [GRCh38]
Chr19:12297692 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.1490C>G (p.Thr497Ser) single nucleotide variant not specified [RCV004348555] Chr19:12187868 [GRCh38]
Chr19:12298683 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.843A>C (p.Lys281Asn) single nucleotide variant not specified [RCV004355686] Chr19:12187221 [GRCh38]
Chr19:12298036 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.1391G>A (p.Arg464Gln) single nucleotide variant not specified [RCV004353802] Chr19:12187769 [GRCh38]
Chr19:12298584 [GRCh37]
Chr19:19p13.2		 uncertain significance
GRCh37/hg19 19p13.2(chr19:12281048-13573342)x3 copy number gain not provided [RCV003485193] Chr19:12281048..13573342 [GRCh37]
Chr19:19p13.2		 likely pathogenic
GRCh37/hg19 19p13.2(chr19:10441330-13077352)x1 copy number loss not specified [RCV003986120] Chr19:10441330..13077352 [GRCh37]
Chr19:19p13.2		 pathogenic
NM_003437.5(ZNF136):c.1138C>G (p.Arg380Gly) single nucleotide variant not specified [RCV004489318] Chr19:12187516 [GRCh38]
Chr19:12298331 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.557A>G (p.His186Arg) single nucleotide variant not specified [RCV004489321] Chr19:12186935 [GRCh38]
Chr19:12297750 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.127A>G (p.Ile43Val) single nucleotide variant not specified [RCV004489319] Chr19:12185908 [GRCh38]
Chr19:12296723 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.671A>G (p.Tyr224Cys) single nucleotide variant not specified [RCV004489322] Chr19:12187049 [GRCh38]
Chr19:12297864 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.961C>T (p.Pro321Ser) single nucleotide variant not specified [RCV004489323] Chr19:12187339 [GRCh38]
Chr19:12298154 [GRCh37]
Chr19:19p13.2		 uncertain significance
NM_003437.5(ZNF136):c.265A>C (p.Asn89His) single nucleotide variant not specified [RCV004489320] Chr19:12186643 [GRCh38]
Chr19:12297458 [GRCh37]
Chr19:19p13.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:945
Count of miRNA genes:468
Interacting mature miRNAs:514
Transcripts:ENST00000343979, ENST00000398616, ENST00000418338, ENST00000425827, ENST00000439995, ENST00000464860, ENST00000476676
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D19S1165  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371912,294,333 - 12,294,487UniSTSGRCh37
Build 361912,155,333 - 12,155,487RGDNCBI36
Celera1912,188,704 - 12,188,854RGD
Cytogenetic Map19p13.2-p13.1UniSTS
Cytogenetic Map19p13.2UniSTS
HuRef1911,869,381 - 11,869,531UniSTS
Marshfield Genetic Map1936.22UniSTS
deCODE Assembly Map1932.22UniSTS
ZNF136_8744  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371912,298,862 - 12,299,731UniSTSGRCh37
Build 361912,159,862 - 12,160,731RGDNCBI36
Celera1912,192,809 - 12,193,678RGD
HuRef1911,873,906 - 11,874,775UniSTS
RH79111  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371912,299,367 - 12,299,459UniSTSGRCh37
Build 361912,160,367 - 12,160,459RGDNCBI36
Celera1912,193,314 - 12,193,406RGD
Cytogenetic Map19p13.2UniSTS
HuRef1911,874,411 - 11,874,503UniSTS
GeneMap99-GB4 RH Map1971.07UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 55 230 310 3 408 4 713 24 476 58 541 427 3 1 157 523 3 1
Low 2381 2600 1413 618 1395 458 3619 2136 3243 359 914 1183 171 1047 2245 3 1
Below cutoff 2 161 3 3 148 3 24 37 15 2 5 2 20

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_052983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001348013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001348014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054322009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC012618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC022415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK123008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK299601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL537987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY500356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP420506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ574220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN429121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA783495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB200139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB369850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF456501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT584587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U09367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000343979   ⟹   ENSP00000344162
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1912,163,096 - 12,189,871 (+)Ensembl
RefSeq Acc Id: ENST00000418338   ⟹   ENSP00000397176
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1912,163,116 - 12,186,157 (+)Ensembl
RefSeq Acc Id: ENST00000425827   ⟹   ENSP00000403707
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1912,163,064 - 12,186,602 (+)Ensembl
RefSeq Acc Id: ENST00000439995   ⟹   ENSP00000388759
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1912,163,064 - 12,186,843 (+)Ensembl
RefSeq Acc Id: ENST00000464860
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1912,184,618 - 12,188,793 (+)Ensembl
RefSeq Acc Id: ENST00000476676
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1912,185,829 - 12,186,678 (+)Ensembl
RefSeq Acc Id: ENST00000652580   ⟹   ENSP00000498578
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1912,163,070 - 12,189,183 (+)Ensembl
RefSeq Acc Id: NM_001348013   ⟹   NP_001334942
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381912,163,096 - 12,189,871 (+)NCBI
T2T-CHM13v2.01912,291,345 - 12,318,112 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001348014   ⟹   NP_001334943
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381912,163,096 - 12,189,871 (+)NCBI
T2T-CHM13v2.01912,291,345 - 12,318,112 (+)NCBI
Sequence:
RefSeq Acc Id: NM_003437   ⟹   NP_003428
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381912,163,096 - 12,189,871 (+)NCBI
GRCh371912,273,872 - 12,300,064 (+)RGD
Build 361912,134,919 - 12,161,064 (+)NCBI Archive
HuRef1911,848,917 - 11,875,108 (+)ENTREZGENE
CHM1_11912,273,699 - 12,299,875 (+)NCBI
T2T-CHM13v2.01912,291,345 - 12,318,112 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054322009   ⟹   XP_054177984
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01912,287,953 - 12,318,112 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_003428   ⟸   NM_003437
- Peptide Label: isoform 1
- UniProtKB: P52737 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001334943   ⟸   NM_001348014
- Peptide Label: isoform 3
- UniProtKB: A0A494C0J2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001334942   ⟸   NM_001348013
- Peptide Label: isoform 2
- UniProtKB: P52737 (UniProtKB/Swiss-Prot),   B4DS70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000388759   ⟸   ENST00000439995
RefSeq Acc Id: ENSP00000403707   ⟸   ENST00000425827
RefSeq Acc Id: ENSP00000498578   ⟸   ENST00000652580
RefSeq Acc Id: ENSP00000397176   ⟸   ENST00000418338
RefSeq Acc Id: ENSP00000344162   ⟸   ENST00000343979
RefSeq Acc Id: XP_054177984   ⟸   XM_054322009
- Peptide Label: isoform X1
- UniProtKB: P52737 (UniProtKB/Swiss-Prot)
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P52737-F1-model_v2 AlphaFold P52737 1-540 view protein structure

Promoters
RGD ID:6796258
Promoter ID:HG_KWN:28979
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000344151,   OTTHUMT00000344154,   OTTHUMT00000344155,   OTTHUMT00000344156
Position:
Human AssemblyChrPosition (strand)Source
Build 361912,134,699 - 12,135,199 (+)MPROMDB
RGD ID:7238661
Promoter ID:EPDNEW_H25077
Type:initiation region
Name:ZNF136_1
Description:zinc finger protein 136
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381912,163,099 - 12,163,159EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:12920 AgrOrtholog
COSMIC ZNF136 COSMIC
Ensembl Genes ENSG00000196646 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000343979 ENTREZGENE
  ENST00000343979.6 UniProtKB/Swiss-Prot
  ENST00000418338.1 UniProtKB/TrEMBL
  ENST00000425827.5 UniProtKB/TrEMBL
  ENST00000439995.5 UniProtKB/TrEMBL
  ENST00000652580 ENTREZGENE
  ENST00000652580.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000196646 GTEx
HGNC ID HGNC:12920 ENTREZGENE
Human Proteome Map ZNF136 Human Proteome Map
InterPro KRAB UniProtKB/Swiss-Prot
  KRAB_dom_sf UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:7695 UniProtKB/Swiss-Prot
NCBI Gene 7695 ENTREZGENE
OMIM 604078 OMIM
PANTHER IP01201P-RELATED UniProtKB/TrEMBL
  ZINC FINGER AND BTB DOMAIN-CONTAINING UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 771 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 845-LIKE UniProtKB/Swiss-Prot
Pfam KRAB UniProtKB/Swiss-Prot
  zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2_6 UniProtKB/Swiss-Prot
PharmGKB PA37508 PharmGKB
PROSITE KRAB UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART KRAB UniProtKB/Swiss-Prot
  ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/Swiss-Prot
  SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A494C0J2 ENTREZGENE, UniProtKB/TrEMBL
  B4DS70 ENTREZGENE, UniProtKB/TrEMBL
  C9J2Q9_HUMAN UniProtKB/TrEMBL
  C9JJK8_HUMAN UniProtKB/TrEMBL
  C9JR58_HUMAN UniProtKB/TrEMBL
  P52737 ENTREZGENE, UniProtKB/Swiss-Prot