SFRP1 (secreted frizzled-related protein 1)

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Keyword

Gene: SFRP1 (secreted frizzled-related protein 1) Homo sapiens

Symbol:

SFRP1

Name:

secreted frizzled-related protein 1

Description:

This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

FRP; FRP-1; FRP1; FrzA; OTTHUMP00000225802; SARP-2; SARP2; secreted apoptosis-related protein 2; secreted frizzled-related protein 1; sFRP-1

Orthologs:

Mus musculus : Sfrp1 (secreted frizzled-related protein 1) MGI
Rattus norvegicus : Sfrp1 (secreted frizzled-related protein 1)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	8	41,193,654 - 41,241,167	-	NCBI
Human Genome Assembly HuRef	8	39,647,919 - 39,695,566	-	NCBI
Human Genome Assembly GRCh37	8	41,119,476 - 41,166,990	-	NCBI
Human Genome Assembly Build 36	8	41,238,635 - 41,286,137	-	NCBI
Human Cytogenetic Map	8	p11.21		NCBI
Human Genome Assembly	8	41,238,635 - 41,286,137		NCBI