RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: pneumonia
Accession: DOID:552
browse the term
Definition: A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing. (DO)
Synonyms: exact_synonym: Experimental Lung Inflammation; Lobar Pneumonia; Lobar Pneumonias; Lung Inflammation; Lung Inflammations; Pneumonias; Pneumonitides; Pneumonitis; Pulmonary Inflammation; acute pneumonia; experimental lung inflammations; pulmonary inflammations
primary_id: MESH:D011014
xref: EFO:0003106 ; EFO:1001991 ; NCI:C3333
For additional species annotation, visit the
Alliance of Genome Resources .
GViewer not supported for the selected species.
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Abcf1
ATP binding cassette subfamily F member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936837:248,133...265,016
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Abo
ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
severity
ISO
DNA:polymorphism:cds:allele A (human)
RGD
PMID:4375858
RGD:39938844
NCBI chrNW_004936570:1,315,192...1,322,719
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Adora1
adenosine A1 receptor
ISO
RGD
PMID:15630442
RGD:5129098
NCBI chrNW_004936567:1,430,128...1,508,626
Ensembl chrNW_004936567:1,429,817...1,462,532
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Adora2a
adenosine A2a receptor
ISO
associated with Lung Injury associated with Anemia, Sickle Cell
RGD
PMID:17601796 PMID:18703794 PMID:20798237
RGD:4890358 RGD:4890364 RGD:4890376
NCBI chrNW_004936619:597,970...618,564
Ensembl chrNW_004936619:608,441...616,779
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Adrb2
adrenoceptor beta 2
ISO
RGD
PMID:19925785
RGD:4145041
NCBI chrNW_004936504:5,985,407...5,987,453
Ensembl chrNW_004936504:5,985,960...5,987,210
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Agt
angiotensinogen
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:28960804
NCBI chrNW_004936484:19,713,299...19,721,144
Ensembl chrNW_004936484:19,716,165...19,721,261
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Ahr
aryl hydrocarbon receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23337360
NCBI chrNW_004936546:3,737,908...3,783,492
Ensembl chrNW_004936546:3,737,851...3,783,588
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Bdkrb2
bradykinin receptor B2
ISO
RGD
PMID:15021973
RGD:4891030
NCBI chrNW_004936604:548,844...551,031
Ensembl chrNW_004936604:548,847...549,956
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C3
complement C3
ISO
RGD
PMID:10886251
RGD:5129562
NCBI chrNW_004936588:3,985,732...4,023,221
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C3ar1
complement C3a receptor 1
ISO
associated with Respiratory Syncytial Virus Infections
RGD
PMID:17079327
RGD:5129688
NCBI chrNW_004936892:347,547...355,143
Ensembl chrNW_004936892:347,842...349,296
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C5
complement C5
ISO
associated with Respiratory Syncytial Virus Infections
RGD
PMID:3631740 PMID:17079327
RGD:5129688 RGD:5130161
NCBI chrNW_004936487:9,391,774...9,474,168
Ensembl chrNW_004936487:9,391,804...9,474,159
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Ccl17
C-C motif chemokine ligand 17
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:lung
CTD RGD
PMID:15993846 PMID:21625544
RGD:2306304
NCBI chrNW_004936475:9,475,013...9,476,326
Ensembl chrNW_004936475:9,474,961...9,476,398
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Ccl19
C-C motif chemokine ligand 19
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936524:2,765,271...2,767,259
Ensembl chrNW_004936524:2,765,267...2,767,385
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Ccl20
C-C motif chemokine ligand 20
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936525:8,238,128...8,240,974
Ensembl chrNW_004936525:8,237,831...8,240,974
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Ccl22
C-C motif chemokine ligand 22
ISO
mRNA:increased expression:lung
RGD
PMID:15993846
RGD:2306304
NCBI chrNW_004936475:9,432,505...9,436,240
Ensembl chrNW_004936475:9,432,505...9,436,240
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Ccl24
C-C motif chemokine ligand 24
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936543:2,400,743...2,403,558
Ensembl chrNW_004936543:2,400,768...2,403,217
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Ccl8
C-C motif chemokine ligand 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936538:805,273...806,715
Ensembl chrNW_004936538:805,259...806,695
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Ccr3
C-C motif chemokine receptor 3
ISO
mRNA:increased expression:lung
RGD
PMID:19762220
RGD:4145622
NCBI chrNW_004936596:223,660...224,739
Ensembl chrNW_004936596:223,660...224,739
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Ccr6
C-C motif chemokine receptor 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936489:16,669,297...16,689,451
Ensembl chrNW_004936489:16,669,297...16,689,451
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Ccr7
C-C motif chemokine receptor 7
ISO
mRNA, protein:increased expression:lung
RGD
PMID:16394278
RGD:5130919
NCBI chrNW_004936490:15,575,764...15,579,766
Ensembl chrNW_004936490:15,575,764...15,579,757
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Ccr9
C-C motif chemokine receptor 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936695:55,788...59,251
Ensembl chrNW_004936695:55,788...59,251
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Cd14
CD14 molecule
ISO
protein:increased expression:multiple
RGD
PMID:20302606
RGD:4144794
NCBI chrNW_004936531:9,572,392...9,575,771
Ensembl chrNW_004936531:9,571,796...9,575,923
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Cd40lg
CD40 ligand
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936513:10,607,617...10,620,403
Ensembl chrNW_004936513:10,607,617...10,620,403
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Crhr2
corticotropin releasing hormone receptor 2
ISO
RGD
PMID:16855006
RGD:5130933
NCBI chrNW_004936478:6,901,098...6,947,719
Ensembl chrNW_004936478:6,899,017...6,947,790
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Crp
C-reactive protein
severity disease_progression
ISO
RGD
PMID:21258955 PMID:21439658
RGD:5131283 RGD:5131291
NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606
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Csf2
colony stimulating factor 2
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:11732872 PMID:19633061
RGD:4142837
NCBI chrNW_004936647:3,081,896...3,083,864
Ensembl chrNW_004936647:3,081,896...3,083,864
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Csf3r
colony stimulating factor 3 receptor
ISO
mRNA:increased expression:bronchoalveolar lavage (human)
RGD
PMID:32407669
RGD:30296672
NCBI chrNW_004936474:18,877,036...18,887,574
Ensembl chrNW_004936474:18,877,375...18,887,530
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Csk
C-terminal Src kinase
ISO
RGD
PMID:14975240
RGD:5134363
NCBI chrNW_004936471:33,757,778...33,777,871
Ensembl chrNW_004936471:33,757,772...33,778,933
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Cx3cl1
C-X3-C motif chemokine ligand 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936475:9,443,851...9,454,715
Ensembl chrNW_004936475:9,443,733...9,455,062
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Cxcl10
C-X-C motif chemokine ligand 10
ISO
associated with Lupus Erythematosus, Systemic;mRNA:increased expression:lung
RGD
PMID:14979941 PMID:15265940
RGD:5135445 RGD:5135491
NCBI chrNW_004936676:60,869...63,028
Ensembl chrNW_004936676:60,621...63,106
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Cxcl9
C-X-C motif chemokine ligand 9
ISO
CTD Direct Evidence: marker/mechanism protein:increased expression:serum
CTD RGD
PMID:15265940 PMID:17052299 PMID:21625544
RGD:5135440 RGD:5135445
NCBI chrNW_004936676:33,580...40,323
Ensembl chrNW_004936676:32,128...40,329
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Cxcr3
C-X-C motif chemokine receptor 3
ISO
associated with Lupus Erythematosus, Systemic;mRNA:increased expression:lung CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:14979941 PMID:15265940 PMID:21625544
RGD:5135445 RGD:5135491
NCBI chrNW_004936762:66,636...69,694
Ensembl chrNW_004936762:66,636...69,373
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Defb1
defensin beta 1
ISO
protein:increased expression:serum
RGD
PMID:17000097
RGD:4892262
NCBI chrNW_004936615:4,780,229...4,790,516
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Edn1
endothelin 1
severity
ISO
protein:increased secretion:plasma (human)
RGD
PMID:20529344
RGD:4144879
NCBI chrNW_004936534:885,489...892,292
Ensembl chrNW_004936534:885,287...891,772
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Egf
epidermal growth factor
resistance
ISO
RGD
PMID:21701422
RGD:6906904
NCBI chrNW_004936563:1,058,803...1,181,393
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Egr1
early growth response 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:29787794
NCBI chrNW_004936531:7,625,956...7,629,041
Ensembl chrNW_004936531:7,625,892...7,629,749
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Grp
gastrin releasing peptide
ISO
protein:increased expression:serum (human)
RGD
PMID:30146822
RGD:401700396
NCBI chrNW_004936497:5,473,293...5,487,344
Ensembl chrNW_004936497:5,476,800...5,487,358
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Hdc
histidine decarboxylase
ISO
RGD
PMID:14556983
RGD:5143922
NCBI chrNW_004936471:12,303,802...12,324,613
Ensembl chrNW_004936471:12,304,130...12,324,570
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Hmox1
heme oxygenase 1
susceptibility
ISO
DNA:allele:promoter:L allele of the (GT)n repeat (>30 repeats) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:16582079
RGD:1601608
NCBI chrNW_004936492:5,042,353...5,049,216
Ensembl chrNW_004936492:5,042,330...5,049,311
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Icam1
intercellular adhesion molecule 1
treatment
ISO
associated with Reperfusion Injury
RGD
PMID:22882462
RGD:8547727
NCBI chrNW_004936659:616,570...627,172
Ensembl chrNW_004936659:616,752...627,174
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Ifnar1
interferon alpha and beta receptor subunit 1
resistance
ISO
Cryptococcus (yeast) pneumonia
RGD
PMID:18566423
RGD:5490275
NCBI chrNW_004936500:8,953,809...8,975,261
Ensembl chrNW_004936500:8,953,049...8,973,978
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Ifng
interferon gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452
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Ikbkb
inhibitor of nuclear factor kappa B kinase subunit beta
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20080200 PMID:31095431
RGD:7495767
NCBI chrNW_004936785:358,128...406,751
Ensembl chrNW_004936785:356,168...406,773
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Il10
interleukin 10
disease_progression
ISO
protein:increased expression:blood
RGD
PMID:20595152
RGD:4140400
NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502
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Il13
interleukin 13
ISO
CTD Direct Evidence: marker/mechanism associated with Respiratory Distress Syndrome, Newborn; protein:increased expression:bronchoalveolar lavage fluid
CTD RGD
PMID:19695190 PMID:21625544
RGD:4145774
NCBI chrNW_004936647:2,529,933...2,532,503
Ensembl chrNW_004936647:2,530,491...2,532,373
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Il13ra2
interleukin 13 receptor subunit alpha 2
ISO
mRNA:increased expression:lung, fibroblast
RGD
PMID:15161635
RGD:4890021
NCBI chrNW_004936499:860,179...883,884
Ensembl chrNW_004936499:863,599...883,855
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Il17a
interleukin 17A
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20498020 PMID:21625544 PMID:22848348
RGD:4888524 RGD:9068417
NCBI chrNW_004936476:8,621,860...8,625,008
Ensembl chrNW_004936476:8,621,860...8,625,008
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Il18
interleukin 18
ISO
mRNA, protein:increased expression:lung,bronchoalveolar fluid associated with reperfusion injury protein:increased expression:serum CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:11739527 PMID:15955140 PMID:16052682 PMID:17400729 PMID:21625544
RGD:4889590 RGD:4889825 RGD:4889836 RGD:729357
NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189
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Il1a
interleukin 1 alpha
ISO
mRNA:increased expression:lung
RGD
PMID:8806881
RGD:7794765
NCBI chrNW_004936783:1,210,715...1,218,315
Ensembl chrNW_004936783:1,210,809...1,218,315
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Il1b
interleukin 1 beta
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:bronchoalveolar lavage (human) mRNA:increased expression:lung mRNA, protein:increased expression:lung
CTD RGD
PMID:19825784 PMID:19901996 PMID:20007584 PMID:20155581 PMID:20476872 PMID:21625544 PMID:32407669 More...
RGD:30296672 RGD:4142536 RGD:4142812 RGD:4142827 RGD:4142831 RGD:4143211
NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165
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Il1r1
interleukin 1 receptor type 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936713:808,761...881,070
Ensembl chrNW_004936713:808,659...881,076
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Il1r2
interleukin 1 receptor type 2
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:bronchoalveolar lavage (human)
CTD RGD
PMID:21625544 PMID:32407669
RGD:30296672
NCBI chrNW_004936713:679,680...716,801
Ensembl chrNW_004936713:701,155...716,650
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Il1rn
interleukin 1 receptor antagonist
no_association disease_progression
ISO
mRNA:increased expression:lung mRNA:increased expression:bronchoalveolar lavage (human) DNA:polymorphism (human) mRNA:increased expression:bronchioalveolar lavage fluid, neutrophil (rat) DNA:polymorphism:intron (human)
RGD
PMID:1385928 PMID:16369129 PMID:17569781 PMID:18838927 PMID:19900796 PMID:32407669 More...
RGD:30296672 RGD:4142865 RGD:4142871 RGD:4143204 RGD:4143213 RGD:8551846
NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340
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Il27
interleukin 27
ISO
RGD
PMID:19124731
RGD:5128483
NCBI chrNW_004936501:11,972,715...11,978,152
Ensembl chrNW_004936501:11,973,385...11,976,583
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Il2rb
interleukin 2 receptor subunit beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936492:3,795,940...3,805,822
Ensembl chrNW_004936492:3,795,940...3,805,774
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Il33
interleukin 33
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24453940
NCBI chrNW_004936539:763,755...791,461
Ensembl chrNW_004936539:623,248...791,470
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Il4r
interleukin 4 receptor
ISO
mRNA:decreased expression:bronchoalveolar lavage (human)
RGD
PMID:32407669
RGD:30296672
NCBI chrNW_004936501:11,025,590...11,058,807
Ensembl chrNW_004936501:11,025,567...11,058,818
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Il5ra
interleukin 5 receptor subunit alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936577:2,776,608...2,797,303
Ensembl chrNW_004936577:2,776,721...2,797,300
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Il6
interleukin 6
disease_progression
ISO
protein:increased expression:blood CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:20595152 PMID:21625544
RGD:4140400
NCBI chrNW_004936549:7,015,595...7,016,246
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Il6st
interleukin 6 cytokine family signal transducer
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936480:11,867,573...11,913,563
Ensembl chrNW_004936480:11,884,582...11,909,635
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Irf5
interferon regulatory factor 5
severity
ISO
RGD
PMID:29847542
RGD:40907064
NCBI chrNW_004936579:6,138,372...6,149,531
Ensembl chrNW_004936579:6,138,281...6,145,205
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Itga2
integrin subunit alpha 2
treatment
ISO
RGD
PMID:11207307
RGD:8693217
NCBI chrNW_004936480:14,320,292...14,417,828
Ensembl chrNW_004936480:14,320,692...14,417,786
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Itga4
integrin subunit alpha 4
treatment
ISO
RGD
PMID:8703473
RGD:9698424
NCBI chrNW_004936509:10,215,283...10,293,653
Ensembl chrNW_004936509:10,215,283...10,292,252
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Itgb2
integrin subunit beta 2
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:10030843 PMID:21625544
RGD:6482228
NCBI chrNW_004936778:1,286,475...1,311,184
Ensembl chrNW_004936778:1,286,341...1,311,194
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Itgb3
integrin subunit beta 3
disease_progression
ISO
RGD
PMID:12746502
RGD:5100478
NCBI chrNW_004936541:2,822,789...2,871,069
Ensembl chrNW_004936541:2,815,738...2,871,035
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Lcn2
lipocalin 2
exacerbates
ISO
associated with Escherichia Coli Infections
RGD
PMID:20633248
RGD:126779583
NCBI chrNW_004936487:15,721,752...15,725,396
Ensembl chrNW_004936487:15,721,684...15,728,221
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Lias
lipoic acid synthetase
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:32017981
NCBI chrNW_004936482:7,068,326...7,085,571
Ensembl chrNW_004936482:7,068,445...7,084,504
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LOC101955076
low affinity immunoglobulin gamma Fc region receptor III-A
treatment
ISO
associated with Hodgkin Disease;DNA:SNP:exon:p.F158V (rs396991) (human)
RGD
PMID:20423913
RGD:11352258
NCBI chrNW_004937131:42,523...49,533
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LOC101964209
C-C chemokine receptor type 1
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:20870892 PMID:21625544
RGD:5688175
NCBI chrNW_004936596:177,774...183,186
Ensembl chrNW_004936596:177,812...183,186
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LOC101964975
interleukin-8
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:bronchoalveolar lavage (human)
CTD RGD
PMID:21625544 PMID:32407669
RGD:30296672
NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353
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LOC101968920
eotaxin
ISO
mRNA, protein:increased expression:lung, respiratory system fluid/secretion CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:10595930 PMID:11290805 PMID:21625544
RGD:4145445 RGD:4145450
NCBI chrNW_004936538:835,436...848,907
Ensembl chrNW_004936538:835,859...837,710 Ensembl chrNW_004936538:835,859...837,710
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LOC101968921
angiotensin-converting enzyme
disease_progression
ISO
associated with Hypertension
RGD
PMID:17727310 PMID:19455553 PMID:20051911
RGD:4140916 RGD:4140918 RGD:4140922
NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177
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LOC101969148
cytochrome P450 1A1
susceptibility
ISO
DNA:polymorphism (human)
RGD
PMID:15928955
RGD:4142512
NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332
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LOC101973029
cytochrome P450 2E1
ISO
protein:increased expression:alveolus, epithelial cell DNA:polymorphism (human)
RGD
PMID:14698565 PMID:15928955
RGD:4142512 RGD:4892223
NCBI chrNW_004936486:19,691,822...19,702,684
Ensembl chrNW_004936486:19,691,822...19,702,102
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LOC101977665
tumor necrosis factor ligand superfamily member 12
ISO
mRNA:decreased expression:bronchoalveolar lavage (human)
RGD
PMID:32407669
RGD:30296672
NCBI chrNW_004936595:831,252...839,783
Ensembl chrNW_004936595:830,466...839,748
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Mif
macrophage migration inhibitory factor
severity
ISO
DNA:repeats:promoter
RGD
PMID:19346297
RGD:4891058
NCBI chrNW_004936619:1,207,058...1,208,010
Ensembl chrNW_004936619:1,203,746...1,208,442
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Mmp9
matrix metallopeptidase 9
ISO
RGD
PMID:18007984
RGD:5130157
NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793
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Muc1
mucin 1, cell surface associated
ISO
protein:increased expression:serum
RGD
PMID:11802251
RGD:5131281
NCBI chrNW_004936580:4,691,870...4,694,092
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Muc2
mucin 2, oligomeric mucus/gel-forming
treatment
ISO
RGD
PMID:23590300
RGD:7349359
NCBI chrNW_004936816:60,499...91,628
Ensembl chrNW_004936816:60,499...91,628
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Myd88
MYD88 innate immune signal transduction adaptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26882889
NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372
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Mylk
myosin light chain kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15863634
NCBI chrNW_004936725:1,418,930...1,594,697
Ensembl chrNW_004936725:1,424,130...1,592,840
G
Nfkbia
NFKB inhibitor alpha
susceptibility
ISO
associated with combined immunodeficiency;DNA:missense mutation:CDS:c.106T>G (p.S36A) (human)
RGD
PMID:31683054
RGD:126925985
NCBI chrNW_004936494:9,537,793...9,541,187
Ensembl chrNW_004936494:9,537,008...9,541,612
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Nrp1
neuropilin 1
treatment
ISO
RGD
PMID:36373992
RGD:401901166
NCBI chrNW_004936574:1,694,433...1,834,720
Ensembl chrNW_004936574:1,694,336...1,834,720
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Parp1
poly(ADP-ribose) polymerase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20561897
NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642
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Pomc
proopiomelanocortin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:6254450
NCBI chrNW_004936493:7,060,747...7,065,276
Ensembl chrNW_004936493:7,061,587...7,065,109
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Serpine1
serpin family E member 1
disease_progression
ISO
DNA:polymorphism:promoter: Pneumonia, Ventilator-Associated; protein:increased expression:Bronchoalveolar Lavage Fluid
RGD
PMID:19387177 PMID:20473240
RGD:4143511 RGD:4143525
NCBI chrNW_004936543:1,032,543...1,040,956
Ensembl chrNW_004936543:1,032,794...1,039,123
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Sftpb
surfactant protein B
ISO
RGD
PMID:12594064 PMID:15967375 PMID:16024721
RGD:4143393 RGD:4143394 RGD:4143412
NCBI chrNW_004936712:1,614,979...1,621,207
Ensembl chrNW_004936712:1,614,979...1,622,466
G
Sftpc
surfactant protein C
ISO
RGD
PMID:15967375
RGD:4143394
NCBI chrNW_004936555:5,966,610...5,982,083
Ensembl chrNW_004936555:5,979,417...5,982,011
G
Sftpd
surfactant protein D
ISO
associated with Bronchitis;protein:decreased expression:lung
RGD
PMID:15967375 PMID:17925426 PMID:18266831
RGD:4143394 RGD:4143504 RGD:4143517
NCBI chrNW_004936716:60,754...73,010
Ensembl chrNW_004936716:60,656...73,099
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Sirt1
sirtuin 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:24633890
NCBI chrNW_004936521:10,296,097...10,316,673
Ensembl chrNW_004936521:10,296,097...10,322,215
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Slc11a2
solute carrier family 11 member 2
ISO
RGD
PMID:21278260
RGD:5688709
NCBI chrNW_004936512:8,590,302...8,622,121
Ensembl chrNW_004936512:8,586,262...8,623,597
G
Spp1
secreted phosphoprotein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936905:148,956...156,023
Ensembl chrNW_004936905:148,945...156,079
G
Tgfb1
transforming growth factor beta 1
severity
ISO
CTD Direct Evidence: marker/mechanism protein:increased expression:lung
CTD RGD
PMID:19181604 PMID:19965809 PMID:21625544
RGD:4145120 RGD:4145141
NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272
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Tlr2
toll like receptor 2
susceptibility
ISO
RGD
PMID:19011150
RGD:4145330
NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788
G
Tlr4
toll like receptor 4
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:20357263 PMID:26882889
RGD:4142858
NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095
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Tnc
tenascin C
ISO
protein:increased expression:serum, respiratory system fluid/secretion
RGD
PMID:19721293
RGD:4889573
NCBI chrNW_004936487:4,172,263...4,256,780
Ensembl chrNW_004936487:4,172,886...4,233,126
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Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:21625544 PMID:28917655 PMID:34390737
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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Tnfrsf1a
TNF receptor superfamily member 1A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21625544
NCBI chrNW_004936709:1,407,327...1,421,448
Ensembl chrNW_004936709:1,407,278...1,421,921
G
Tnfrsf1b
TNF receptor superfamily member 1B
susceptibility
ISO
Idiopathic Pneumonia Syndrome associated with Carcinoma, Non-Small-Cell Lung; DNA:snp:cds:p.M196R rs1061622 (human) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:18664626 PMID:20811626 PMID:21625544
RGD:5131286 RGD:5131448
NCBI chrNW_004936474:908,414...935,765
Ensembl chrNW_004936474:908,485...934,177
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Vdr
vitamin D receptor
susceptibility
ISO
DNA:SNP: :rs2239185(human)
RGD
PMID:17224129 PMID:25367052
RGD:11074745 RGD:4889851
NCBI chrNW_004936512:5,741,836...5,800,999
Ensembl chrNW_004936512:5,740,748...5,801,109
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Edn1
endothelin 1
ISO
protein:increased secretion:plasma (rat)
RGD
PMID:19262391
RGD:4145069
NCBI chrNW_004936534:885,489...892,292
Ensembl chrNW_004936534:885,287...891,772
G
Il1a
interleukin 1 alpha
ISO
protein:increased expression:Bronchoalveolar Lavage Fluid
RGD
PMID:18042282
RGD:4142854
NCBI chrNW_004936783:1,210,715...1,218,315
Ensembl chrNW_004936783:1,210,809...1,218,315
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LOC101968921
angiotensin-converting enzyme
ISO
associated with Cerebrovascular Accident
RGD
PMID:14990394
RGD:4140926
NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177
G
Nos2
nitric oxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15607125
NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051
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Tnf
tumor necrosis factor
ISO
protein:increased expression:Bronchoalveolar Lavage Fluid
RGD
PMID:18042282
RGD:4142854
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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Abcc1
ATP binding cassette subfamily C member 1 (ABCC1 blood group)
ISO
RGD
PMID:11238654
RGD:5128828
NCBI chrNW_004936501:3,400,971...3,467,061
Ensembl chrNW_004936501:3,401,285...3,470,460
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Ace2
angiotensin converting enzyme 2
ISO
associated with Pseudomonas Infections;mRNA, protein:altered expression, altered activity:lung (mouse)
RGD
PMID:31645418
RGD:40818279
NCBI chrNW_004936470:4,964,526...5,011,808
Ensembl chrNW_004936470:4,965,332...5,011,702
G
Ager
advanced glycosylation end-product specific receptor
severity
ISO
RGD
PMID:21629785
RGD:6767559
NCBI chrNW_004936727:1,418,342...1,422,005
Ensembl chrNW_004936727:1,418,799...1,422,147
G
C3
complement C3
ISO
RGD
PMID:16014897
RGD:5129508
NCBI chrNW_004936588:3,985,732...4,023,221
G
C3ar1
complement C3a receptor 1
ISO
RGD
PMID:16461429
RGD:5129690
NCBI chrNW_004936892:347,547...355,143
Ensembl chrNW_004936892:347,842...349,296
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C5
complement C5
ISO
RGD
PMID:17975174
RGD:5129707
NCBI chrNW_004936487:9,391,774...9,474,168
Ensembl chrNW_004936487:9,391,804...9,474,159
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Cat
catalase
ISO
protein:decreased expression:lung, plasma
RGD
PMID:19842849
RGD:5130748
NCBI chrNW_004936533:3,601,270...3,637,128
Ensembl chrNW_004936533:3,600,955...3,637,422
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Ccl19
C-C motif chemokine ligand 19
ISO
mRNA, protein:increased expression:lung
RGD
PMID:20176793
RGD:5130918
NCBI chrNW_004936524:2,765,271...2,767,259
Ensembl chrNW_004936524:2,765,267...2,767,385
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Ccr7
C-C motif chemokine receptor 7
ISO
RGD
PMID:20176793
RGD:5130918
NCBI chrNW_004936490:15,575,764...15,579,766
Ensembl chrNW_004936490:15,575,764...15,579,757
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Cd14
CD14 molecule
ISO
RGD
PMID:16210672
RGD:4144197
NCBI chrNW_004936531:9,572,392...9,575,771
Ensembl chrNW_004936531:9,571,796...9,575,923
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Cd40
CD40 molecule
ISO
RGD
PMID:20102413
RGD:5132268
NCBI chrNW_004936514:6,936,915...6,947,246
Ensembl chrNW_004936514:6,936,572...6,947,280
G
Cd80
CD80 molecule
ISO
RGD
PMID:20949109
RGD:4892562
NCBI chrNW_004936536:6,462,080...6,483,450
G
Chuk
component of inhibitor of nuclear factor kappa B kinase complex
ISO
RGD
PMID:18643924
RGD:5133701
NCBI chrNW_004936636:33,933...78,990
Ensembl chrNW_004936636:33,673...79,194
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Csf3
colony stimulating factor 3
treatment disease_progression
ISO
associated with Peritonitis;
RGD
PMID:12352049 PMID:21373266
RGD:11039437 RGD:5133733
NCBI chrNW_004936490:15,142,526...15,146,375
Ensembl chrNW_004936490:15,142,808...15,144,487
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Csf3r
colony stimulating factor 3 receptor
disease_progression
ISO
RGD
PMID:17185469
RGD:5133739
NCBI chrNW_004936474:18,877,036...18,887,574
Ensembl chrNW_004936474:18,877,375...18,887,530
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Cxcl10
C-X-C motif chemokine ligand 10
severity
ISO
RGD
PMID:15618188 PMID:16299319
RGD:5135458 RGD:5135459
NCBI chrNW_004936676:60,869...63,028
Ensembl chrNW_004936676:60,621...63,106
G
Cxcl11
C-X-C motif chemokine ligand 11
ISO
RGD
PMID:15618188
RGD:5135459
NCBI chrNW_004936676:72,383...73,697
Ensembl chrNW_004936676:71,667...73,738
G
Cxcl9
C-X-C motif chemokine ligand 9
ISO
RGD
PMID:15618188
RGD:5135459
NCBI chrNW_004936676:33,580...40,323
Ensembl chrNW_004936676:32,128...40,329
G
Cxcr3
C-X-C motif chemokine receptor 3
ISO
RGD
PMID:15618188
RGD:5135459
NCBI chrNW_004936762:66,636...69,694
Ensembl chrNW_004936762:66,636...69,373
G
F2
coagulation factor II, thrombin
ISO
protein:increased expression:lung
RGD
PMID:21897338
RGD:6893486
NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650
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Foxp3
forkhead box P3
severity
ISO
RGD
PMID:25398094
RGD:38501102
NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308
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Gp1ba
glycoprotein Ib platelet subunit alpha
exacerbates
ISO
associated with Escherichia Coli Infections
RGD
PMID:27845343
RGD:42722624
NCBI chrNW_004936677:2,774,076...2,779,660
G
Grk2
G protein-coupled receptor kinase 2
ISO
mRNA:decreased expression:polymorphonuclear leukocyte
RGD
PMID:24465168
RGD:126848796
NCBI chrNW_004936599:2,437,061...2,456,141
Ensembl chrNW_004936599:2,437,032...2,456,147
G
Icam1
intercellular adhesion molecule 1
ISO
protein:increased expression:lung (mouse)
RGD
PMID:19846873
RGD:4145490
NCBI chrNW_004936659:616,570...627,172
Ensembl chrNW_004936659:616,752...627,174
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Ifnar1
interferon alpha and beta receptor subunit 1
severity
ISO
RGD
PMID:19487810
RGD:5490274
NCBI chrNW_004936500:8,953,809...8,975,261
Ensembl chrNW_004936500:8,953,049...8,973,978
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Ifng
interferon gamma
severity
ISO
RGD
PMID:25398094
RGD:38501102
NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452
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Il10
interleukin 10
severity
ISO
RGD
PMID:25398094
RGD:38501102
NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502
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Il15
interleukin 15
ISO
RGD
PMID:17911627
RGD:5000754
NCBI chrNW_004936535:6,344,348...6,358,803
Ensembl chrNW_004936535:6,344,395...6,350,197
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Il17a
interleukin 17A
severity
ISO
RGD
PMID:18802100 PMID:25398094
RGD:38501102 RGD:4889153
NCBI chrNW_004936476:8,621,860...8,625,008
Ensembl chrNW_004936476:8,621,860...8,625,008
G
Il18
interleukin 18
ISO
RGD
PMID:17664259
RGD:4889913
NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189
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Il1b
interleukin 1 beta
severity treatment
ISO
associated with Agranulocytosis
RGD
PMID:7546648 PMID:18596024 PMID:25398094
RGD:10755357 RGD:38501102 RGD:4143205
NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165
G
Il1rl1
interleukin 1 receptor like 1
treatment
ISO
associated with Sepsis associated with Acinetobacter infectious disease
RGD
PMID:20959556 PMID:29508184
RGD:40818077 RGD:5144223
NCBI chrNW_004936713:1,020,969...1,035,012
Ensembl chrNW_004936713:1,021,044...1,035,039
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Il1rn
interleukin 1 receptor antagonist
ISO
RGD
PMID:18322242 PMID:18596024
RGD:4143205 RGD:4143206
NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340
G
Il6
interleukin 6
severity
ISO
RGD
PMID:25398094
RGD:38501102
NCBI chrNW_004936549:7,015,595...7,016,246
G
Irak3
interleukin 1 receptor associated kinase 3
ISO
RGD
PMID:20439918 PMID:28120642
RGD:34888234 RGD:36049799
NCBI chrNW_004936545:4,233,353...4,284,324
Ensembl chrNW_004936545:4,233,358...4,282,806
G
Irf1
interferon regulatory factor 1
ISO
RGD
PMID:11854220
RGD:5128725
NCBI chrNW_004936647:2,686,247...2,693,633
Ensembl chrNW_004936647:2,686,414...2,693,636
G
Irf3
interferon regulatory factor 3
ISO
RGD
PMID:20720199
RGD:4891951
NCBI chrNW_004936664:3,477,750...3,482,489
Ensembl chrNW_004936664:3,475,543...3,481,533
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Itgb3
integrin subunit beta 3
ISO
protein:increased expression:lung, neutrophil
RGD
PMID:15114484
RGD:4993468
NCBI chrNW_004936541:2,822,789...2,871,069
Ensembl chrNW_004936541:2,815,738...2,871,035
G
Lep
leptin
ISO
RGD
PMID:11937559
RGD:5128871
NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334
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Mapk8
mitogen-activated protein kinase 8
severity
ISO
associated with Escherichia Coli Infections
RGD
PMID:22514650
RGD:150340681
NCBI chrNW_004936728:1,775,746...1,893,895
Ensembl chrNW_004936728:1,775,641...1,893,907
G
Mc1r
melanocortin 1 receptor
ISO
RGD
PMID:18304533
RGD:5687324
NCBI chrNW_004936641:193,885...198,730
G
Mmp9
matrix metallopeptidase 9
ISO
protein:increased expression:bronchoalveolar lavage fluid
RGD
PMID:17202364 PMID:19535150
RGD:5129533 RGD:5130727
NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793
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Mpo
myeloperoxidase
ISO
protein:increased activity:bronchoalveolar lavage Fluid:
RGD
PMID:11269653
RGD:5130992
NCBI chrNW_004936490:4,809,773...4,819,070
Ensembl chrNW_004936490:4,809,631...4,819,070
G
Nod1
nucleotide binding oligomerization domain containing 1
ISO
RGD
PMID:19360122
RGD:5131449
NCBI chrNW_004936478:6,717,354...6,768,293
Ensembl chrNW_004936478:6,715,245...6,768,372
G
Nod2
nucleotide binding oligomerization domain containing 2
ISO
RGD
PMID:19360122
RGD:5131449
NCBI chrNW_004936475:3,708,069...3,742,845
Ensembl chrNW_004936475:3,713,362...3,745,982
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Pdpn
podoplanin
ISO
protein:increased expression:lung
RGD
PMID:7864138
RGD:2292375
NCBI chrNW_004936474:1,751,159...1,779,011
Ensembl chrNW_004936474:1,750,944...1,781,156
G
Pecam1
platelet and endothelial cell adhesion molecule 1
ISO
protein:decreased expression:lung
RGD
PMID:12524254
RGD:724645
NCBI chrNW_004936541:4,873,459...4,919,787
Ensembl chrNW_004936541:4,873,182...4,937,500
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Pgf
placental growth factor
ISO
protein:increased expression:plasma
RGD
PMID:16702604
RGD:6483601
NCBI chrNW_004936488:4,098,187...4,111,108
Ensembl chrNW_004936488:4,098,225...4,111,142
G
Pten
phosphatase and tensin homolog
ameliorates
ISO
myeloid knockout
RGD
PMID:21527775
RGD:127285594
NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323
G
Ripk3
receptor interacting serine/threonine kinase 3
ameliorates
ISO
RGD
PMID:28387756
RGD:127229944
NCBI chrNW_004936722:209,019...212,817
Ensembl chrNW_004936722:209,013...212,839
G
Rorc
RAR related orphan receptor C
severity
ISO
RGD
PMID:25398094
RGD:38501102
NCBI chrNW_004936580:1,997,640...2,020,649
Ensembl chrNW_004936580:1,997,640...2,020,649
G
Serpine1
serpin family E member 1
severity
ISO
RGD
PMID:17032919
RGD:4144840
NCBI chrNW_004936543:1,032,543...1,040,956
Ensembl chrNW_004936543:1,032,794...1,039,123
G
Sftpb
surfactant protein B
ISO
associated with Cystic Fibrosis;protein:increased expression:lung
RGD
PMID:12169586 PMID:15271694
RGD:4143403 RGD:4143464
NCBI chrNW_004936712:1,614,979...1,621,207
Ensembl chrNW_004936712:1,614,979...1,622,466
G
Sftpc
surfactant protein C
ISO
RGD
PMID:12169586 PMID:18566429
RGD:4143464 RGD:4144114
NCBI chrNW_004936555:5,966,610...5,982,083
Ensembl chrNW_004936555:5,979,417...5,982,011
G
Sftpd
surfactant protein D
ISO
protein:increased expression:lung associated with Cystic Fibrosis;protein:decreased expression:lung
RGD
PMID:12169586 PMID:15271694
RGD:4143403 RGD:4143464
NCBI chrNW_004936716:60,754...73,010
Ensembl chrNW_004936716:60,656...73,099
G
Stat3
signal transducer and activator of transcription 3
ISO
RGD
PMID:18192501
RGD:6892945
NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402
G
Tgfb1
transforming growth factor beta 1
severity
ISO
RGD
PMID:25398094
RGD:38501102
NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272
G
Tlr2
toll like receptor 2
ISO
RGD
PMID:18768871 PMID:19844782
RGD:4145337 RGD:4889533
NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788
G
Tlr4
toll like receptor 4
ISO
RGD
PMID:16210672 PMID:20650991
RGD:4144172 RGD:4144197
NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095
G
Tlr5
toll like receptor 5
ISO
RGD
PMID:19801452
RGD:5129503
NCBI chrNW_004936526:383,490...387,007
Ensembl chrNW_004936526:383,418...401,552
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Tlr6
toll like receptor 6
ISO
RGD
PMID:19844782
RGD:4889533
NCBI chrNW_004936482:6,607,723...6,610,161
Ensembl chrNW_004936482:6,607,753...6,610,143
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Tnf
tumor necrosis factor
treatment severity disease_progression
ISO
associated with Agranulocytosis
RGD
PMID:7546648 PMID:9310939 PMID:10650487 PMID:12958055
RGD:10449451 RGD:10450564 RGD:10755357 RGD:4143476
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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Tnfrsf1a
TNF receptor superfamily member 1A
ISO
protein:increased expression:serum (mouse)
RGD
PMID:19842848
RGD:5131429
NCBI chrNW_004936709:1,407,327...1,421,448
Ensembl chrNW_004936709:1,407,278...1,421,921
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Tnfrsf1b
TNF receptor superfamily member 1B
ISO
protein:increased expression:serum (mouse)
RGD
PMID:19842848
RGD:5131429
NCBI chrNW_004936474:908,414...935,765
Ensembl chrNW_004936474:908,485...934,177
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Trem1
triggering receptor expressed on myeloid cells 1
severity ameliorates
ISO
RGD
PMID:16960786 PMID:22996209 PMID:24465168
RGD:126848796 RGD:126925987 RGD:127229902
NCBI chrNW_004936476:18,577,825...18,583,675
Ensembl chrNW_004936476:18,574,381...18,583,647
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Zc3h12a
zinc finger CCCH-type containing 12A
ISO
associated with Pseudomonas Infections
RGD
PMID:29695841
RGD:39938967
NCBI chrNW_004936474:19,714,145...19,722,512
Ensembl chrNW_004936474:19,714,153...19,722,528
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Ccl5
C-C motif chemokine ligand 5
ISO
protein:increased secretion:serum (human)
RGD
PMID:20350425
RGD:4892019
NCBI chrNW_004936490:253,279...259,947
Ensembl chrNW_004936490:253,034...259,965
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Cd274
CD274 molecule
ISO
mRNA:increased expression:lung
RGD
PMID:26378990
RGD:41412180
NCBI chrNW_004936539:132,870...145,288
Ensembl chrNW_004936539:132,868...143,602
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Pdcd1
programmed cell death 1
ISO
mRNA:increased expression:lung
RGD
PMID:26378990
RGD:41412180
NCBI chrNW_004936745:152,571...163,712
Ensembl chrNW_004936745:152,612...161,587
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Pik3cd
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
severity
ISO
RGD
PMID:29893841
RGD:40890270
NCBI chrNW_004936623:3,672,201...3,696,959
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Tnfrsf1a
TNF receptor superfamily member 1A
ISO
protein:increased expression:lung, macrophage (human)
RGD
PMID:21144722
RGD:5131112
NCBI chrNW_004936709:1,407,327...1,421,448
Ensembl chrNW_004936709:1,407,278...1,421,921
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Tnfrsf1b
TNF receptor superfamily member 1B
ISO
protein:increased expression:lung, lymphocyte (human)
RGD
PMID:21144722
RGD:5131112
NCBI chrNW_004936474:908,414...935,765
Ensembl chrNW_004936474:908,485...934,177
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Sftpc
surfactant protein C
ISO
OMIM:263000
MouseDO
NCBI chrNW_004936555:5,966,610...5,982,083
Ensembl chrNW_004936555:5,979,417...5,982,011
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Icam1
intercellular adhesion molecule 1
ISO
protein:increased expression:lung, alveolar macrophage (human)
RGD
PMID:19218648
RGD:4145518
NCBI chrNW_004936659:616,570...627,172
Ensembl chrNW_004936659:616,752...627,174
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Il6
interleukin 6
ISO
protein:increased expression:bronchoalveolar lavage (rat)
RGD
PMID:10988147
RGD:11062092
NCBI chrNW_004936549:7,015,595...7,016,246
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Keap1
kelch like ECH associated protein 1
ISO
protein:increased expression:hyperplastic lung epithelium, alveolus (human)
RGD
PMID:20718723
RGD:6893300
NCBI chrNW_004936659:785,059...793,775
Ensembl chrNW_004936659:782,340...793,688
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Mtor
mechanistic target of rapamycin kinase
ISO
RGD
PMID:21444868
RGD:7245946
NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342
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Scgb1a1
secretoglobin family 1A member 1
ISO
protein:increased expression:serum
RGD
PMID:15467329
RGD:5144148
NCBI chrNW_004936581:798,738...801,614
Ensembl chrNW_004936581:798,739...801,633
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Abca3
ATP binding cassette subfamily A member 3
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:15976379 PMID:17597647 PMID:18024538 PMID:18246475 PMID:18317237 PMID:18603241 PMID:18676873 PMID:22145626 PMID:22304854 PMID:22434821 PMID:22435821 PMID:22800827 PMID:22866751 PMID:23166334 PMID:23625987 PMID:24033266 PMID:24136335 PMID:24871971 PMID:25073622 PMID:25553246 PMID:25741868 PMID:27374344 PMID:27516224 PMID:28034695 PMID:28492532 PMID:28642621 PMID:29431110 PMID:29505158 PMID:29566461 PMID:30609409 PMID:30755392 PMID:31589614 PMID:31980526 PMID:32238781 PMID:32532878 PMID:32692933 PMID:33110422 PMID:33526094 PMID:34132118 PMID:34715861 PMID:35170262 PMID:35626240 More...
NCBI chrNW_004936694:1,735,206...1,778,100
Ensembl chrNW_004936694:1,736,207...1,778,116
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Ahrr
aryl-hydrocarbon receptor repressor
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:1,031,696...1,045,032
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Akt1
AKT serine/threonine kinase 1
ISO
mRNA:increased expression:blood plasma (human)
RGD
PMID:31874165
RGD:152995482
NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093
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Apoa1
apolipoprotein A1
ISO
protein: decreased expression: respiratory system fluid/secretion
RGD
PMID:20463180
RGD:5508222
NCBI chrNW_004936542:2,111,055...2,112,626
Ensembl chrNW_004936542:2,111,052...2,112,854
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Atp11a
ATPase phospholipid transporting 11A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23583980
NCBI chrNW_004936472:665,967...750,396
Ensembl chrNW_004936472:669,155...730,035
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Bmp1
bone morphogenetic protein 1
ISO
ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia | ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:24033266 PMID:25741868 PMID:28492532
NCBI chrNW_004936555:5,990,822...6,023,864
Ensembl chrNW_004936555:5,990,836...6,023,878
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Brd4
bromodomain containing 4
ISO
RGD
PMID:23759512
RGD:9586353
NCBI chrNW_004936596:5,176,682...5,246,102
Ensembl chrNW_004936596:5,177,147...5,246,518
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Cep72
centrosomal protein 72
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:886,633...918,445
Ensembl chrNW_004936815:888,701...912,384
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Cflar
CASP8 and FADD like apoptosis regulator
ISO
mRNA,protein:increased expression:lung myofibroblast:
RGD
PMID:22582174
RGD:11341695
NCBI chrNW_004936726:381,888...425,565
Ensembl chrNW_004936726:381,835...423,311
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Ctc1
CST telomere replication complex component 1
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
NCBI chrNW_004936595:1,456,911...1,476,331
Ensembl chrNW_004936595:1,454,508...1,476,593
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Ddr1
discoidin domain receptor tyrosine kinase 1
treatment
ISO
mRNA:increased expression:lung (human)
RGD
PMID:30119248
RGD:151347411
NCBI chrNW_004936837:523,227...538,799
Ensembl chrNW_004936837:523,266...538,833
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Dpp9
dipeptidyl peptidase 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23583980
NCBI chrNW_004936588:2,720,574...2,756,213
Ensembl chrNW_004936588:2,719,642...2,756,248
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Dsp
desmoplakin
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
NCBI chrNW_004936534:5,029,008...5,076,467
Ensembl chrNW_004936534:5,028,911...5,077,199
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Dtnbp1
dystrobrevin binding protein 1
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
NCBI chrNW_004936552:1,787,687...1,926,516
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Ehmt2
euchromatic histone lysine methyltransferase 2
ISO
RGD
PMID:24652950
RGD:9589169
NCBI chrNW_004936727:1,648,451...1,663,294
Ensembl chrNW_004936727:1,648,448...1,663,455
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Ep300
E1A binding protein p300
treatment
ISO
mRNA:increased expression:lung (human)
RGD
PMID:30119248
RGD:151347411
NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138
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Esr1
estrogen receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30165855
NCBI chrNW_004936489:4,616,839...4,887,179
Ensembl chrNW_004936489:4,614,754...4,887,171
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Exoc3
exocyst complex component 3
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:1,005,637...1,022,916
Ensembl chrNW_004936815:1,005,560...1,023,070
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F3
coagulation factor III, tissue factor
ISO
protein:increased expression:respiratory system fluid/secretion
RGD
PMID:10946084
RGD:11060143
NCBI chrNW_004936537:4,637,028...4,647,915
Ensembl chrNW_004936537:4,636,667...4,647,916
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Fam13a
family with sequence similarity 13 member A
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
NCBI chrNW_004936685:1,174,072...1,358,441
Ensembl chrNW_004936685:1,171,584...1,501,074
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Fas
Fas cell surface death receptor
ISO
RGD
PMID:15148335
RGD:11049166
NCBI chrNW_004936735:209,369...234,582
G
Faslg
Fas ligand
ISO
RGD
PMID:15148335
RGD:11049166
NCBI chrNW_004936481:14,789,547...14,795,780
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Fgfr2
fibroblast growth factor receptor 2
ISO
protein:increased expression:lung (human)
RGD
PMID:29722558
RGD:155791445
NCBI chrNW_004936486:10,506,680...10,606,272
Ensembl chrNW_004936486:10,507,097...10,602,019
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Fosl2
FOS like 2, AP-1 transcription factor subunit
ISO
OMIM:178500
MouseDO
NCBI chrNW_004936493:4,308,683...4,327,102
Ensembl chrNW_004936493:4,304,395...4,327,179
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Gper1
G protein-coupled estrogen receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30165855
NCBI chrNW_004936754:1,288,891...1,293,555
Ensembl chrNW_004936754:1,288,912...1,293,427
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Hif1a
hypoxia inducible factor 1 subunit alpha
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:28434932
NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157
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Hps4
HPS4 biogenesis of lysosomal organelles complex 3 subunit 2
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
NCBI chrNW_004936657:1,075,300...1,104,328
Ensembl chrNW_004936657:1,075,261...1,103,055
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Il1rl1
interleukin 1 receptor like 1
ISO
protein:increased expression:serum
RGD
PMID:14555548
RGD:5144236
NCBI chrNW_004936713:1,020,969...1,035,012
Ensembl chrNW_004936713:1,021,044...1,035,039
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Il1rn
interleukin 1 receptor antagonist
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:16199547 PMID:19494218 PMID:21792839 PMID:22940634 PMID:26100510 PMID:28492532 More...
NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340
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Il2ra
interleukin 2 receptor subunit alpha
ISO
RGD
PMID:21309737
RGD:5147438
NCBI chrNW_004936484:8,514,333...8,555,392
Ensembl chrNW_004936484:8,544,062...8,555,332
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LOC101956427
bromodomain-containing protein 9
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:748,112...763,971
Ensembl chrNW_004936815:748,274...763,480
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LOC101971816
laminin subunit alpha-3
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
NCBI chrNW_004936550:3,121,163...3,357,517
Ensembl chrNW_004936550:3,122,089...3,355,319
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Mmp1
matrix metallopeptidase 1
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
NCBI chrNW_004936551:5,167,909...5,175,149
Ensembl chrNW_004936551:5,168,044...5,174,857
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Mmp19
matrix metallopeptidase 19
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
NCBI chrNW_004936646:298,854...304,479
Ensembl chrNW_004936646:299,059...304,430
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Muc1
mucin 1, cell surface associated
ISO
protein:increased expression:serum:
RGD
PMID:22963039
RGD:7244290
NCBI chrNW_004936580:4,691,870...4,694,092
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Muc5b
mucin 5B, oligomeric mucus/gel-forming
susceptibility
ISO
ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia | ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar OMIM
PMID:21506741 PMID:21506748 PMID:23321605 PMID:23692170 PMID:23695349 PMID:23940607 PMID:24033266 PMID:25741868 PMID:25926289 PMID:28492532 PMID:30345907 More...
NCBI chrNW_004936816:174,943...209,241
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Nkd2
NKD inhibitor of WNT signaling pathway 2
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:669,389...701,402
Ensembl chrNW_004936815:669,389...701,402
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Nkx2-1
NK2 homeobox 1
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:25741868 PMID:28492532
NCBI chrNW_004936494:10,517,488...10,520,567
Ensembl chrNW_004936494:10,517,488...10,520,566
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Ntrk2
neurotrophic receptor tyrosine kinase 2
ISO
mRNA:increased expression:lung
RGD
PMID:21330466
RGD:5684550
NCBI chrNW_004936680:267,850...621,467
Ensembl chrNW_004936680:267,596...615,928
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Parn
poly(A)-specific ribonuclease
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25848748
NCBI chrNW_004936501:2,666,908...2,810,159
Ensembl chrNW_004936501:2,666,874...2,810,488
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Parp1
poly(ADP-ribose) polymerase 1
ISO
mRNA,protein:increased expression, increased activity:fibroblast
RGD
PMID:23260200
RGD:10413908
NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642
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Pdcd6
programmed cell death 6
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:1,129,367...1,144,020
Ensembl chrNW_004936815:1,129,352...1,143,992
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Plau
plasminogen activator, urokinase
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:18491991
NCBI chrNW_004936521:5,238,128...5,243,829
Ensembl chrNW_004936521:5,238,093...5,243,877
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Ptgs2
prostaglandin-endoperoxide synthase 2
ISO
DNA:SNPs: :3050G>C, 8473C>T (human) protein:decreased expression:lung:
RGD
PMID:14511257 PMID:20203246 PMID:21319594
RGD:5135280 RGD:5135461 RGD:5135507
NCBI chrNW_004936481:3,821,564...3,828,086
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Rtel1
regulator of telomere elongation helicase 1
ISO
ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia | ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:16199547 PMID:23329068 PMID:23453664 PMID:23959892 PMID:24009516 PMID:24033266 PMID:25047097 PMID:25099625 PMID:25607374 PMID:25620558 PMID:25741868 PMID:26025130 PMID:28099038 PMID:28492532 PMID:29344583 PMID:36655009 PMID:37392813 More...
NCBI chrNW_004936514:10,920,979...10,954,483
Ensembl chrNW_004936514:10,922,322...10,954,402
G
Rtkn2
rhotekin 2
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
NCBI chrNW_004936614:923,977...995,343
G
Sdha
succinate dehydrogenase complex flavoprotein subunit A
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:1,148,963...1,167,585
Ensembl chrNW_004936815:1,148,963...1,167,568
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Setd2
SET domain containing 2, histone lysine methyltransferase
exacerbates
ISO
associated with lung squamous cell carcinoma; DNA:mutations:multiple (human)
RGD
PMID:33533494
RGD:150429642
NCBI chrNW_004936596:795,940...898,823
Ensembl chrNW_004936596:796,601...883,373
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Sftpc
surfactant protein C
ISO
ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia | ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:14735158 PMID:15039969 PMID:15516475 PMID:15709974 PMID:18383112 PMID:19443464 PMID:19910179 PMID:22308375 PMID:23025826 PMID:23775869 PMID:24033266 PMID:24081995 PMID:24347114 PMID:25657025 PMID:25741868 PMID:25782673 PMID:27362365 PMID:28492532 PMID:33526882 More...
NCBI chrNW_004936555:5,966,610...5,982,083
Ensembl chrNW_004936555:5,979,417...5,982,011
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Slc12a7
solute carrier family 12 member 7
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:629,185...666,342
Ensembl chrNW_004936815:636,184...665,019
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Slc6a18
solute carrier family 6 member 18
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:497,465...513,089
Ensembl chrNW_004936815:497,396...513,175
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Slc6a19
solute carrier family 6 member 19
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:515,928...532,877
Ensembl chrNW_004936815:515,762...532,917
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Slc9a3
solute carrier family 9 member A3
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:963,715...999,280
Ensembl chrNW_004936815:963,715...999,280
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Smad2
SMAD family member 2
ISO
mRNA:increased expression:blood plasma (human)
RGD
PMID:31874165
RGD:152995482
NCBI chrNW_004936497:14,723,199...14,812,160
Ensembl chrNW_004936497:14,723,199...14,801,697
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Smad6
SMAD family member 6
ISO
mRNA:decreased expression:blood plasma (human)
RGD
PMID:31874165
RGD:152995482
NCBI chrNW_004936471:26,781,420...26,856,556
Ensembl chrNW_004936471:26,781,549...26,856,571
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St14
ST14 transmembrane serine protease matriptase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26599507
NCBI chrNW_004936572:2,137,820...2,182,674
Ensembl chrNW_004936572:2,137,332...2,182,742
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Stat3
signal transducer and activator of transcription 3
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:22684844 PMID:30481203
RGD:6892915
NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402
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Stn1
STN1 subunit of CST complex
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23583980
NCBI chrNW_004936600:2,230,754...2,266,956
Ensembl chrNW_004936600:2,230,705...2,266,968
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Tert
telomerase reverse transcriptase
ISO
ClinVar Annotator: match by term: Idiopathic Pulmonary Fibrosis | ClinVar Annotator: match by term: Idiopathic fibrosing alveolitis, chronic form | ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:9536098 PMID:12629597 PMID:15814878 PMID:15885610 PMID:16199547 PMID:16247010 PMID:17392301 PMID:17460043 PMID:17576681 PMID:18302718 PMID:18460650 PMID:18635888 PMID:19489057 PMID:19561322 PMID:19674077 PMID:19760749 PMID:20022961 PMID:20044353 PMID:20301779 PMID:20502709 PMID:20858879 PMID:21436073 PMID:21520174 PMID:22364217 PMID:22424236 PMID:22853774 PMID:22863003 PMID:23538340 PMID:23716176 PMID:23901009 PMID:24033266 PMID:24833766 PMID:25271372 PMID:25365545 PMID:25741868 PMID:25785092 PMID:26024875 PMID:26136524 PMID:26365799 PMID:27192671 PMID:27540018 PMID:27848944 PMID:28102861 PMID:28104920 PMID:28154186 PMID:28492532 PMID:28495683 PMID:28677271 PMID:28813500 PMID:29036293 PMID:29483670 PMID:30426156 PMID:30523342 PMID:31268371 PMID:34019641 PMID:34890115 PMID:35776903 More...
NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697
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Tfpi
tissue factor pathway inhibitor
severity
ISO
protein:increased expression:Bronchoalveolar lavage,epithelial cell:
RGD
PMID:10946084
RGD:11060143
NCBI chrNW_004936506:10,103,120...10,172,800
Ensembl chrNW_004936506:10,103,139...10,171,863
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Thbd
thrombomodulin
severity
ISO
RGD
PMID:20418386
RGD:5685036
NCBI chrNW_004936620:2,563,900...2,568,117
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Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism OMIM:178500
CTD MouseDO
PMID:8473757
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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Tollip
toll interacting protein
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
NCBI chrNW_004936816:216,542...245,545
Ensembl chrNW_004936816:216,546...245,606
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Tppp
tubulin polymerization promoting protein
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:842,279...882,985
Ensembl chrNW_004936815:842,087...883,368
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Trip13
thyroid hormone receptor interactor 13
ISO
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar
PMID:12629597 PMID:28492532
NCBI chrNW_004936815:734,029...745,381
Ensembl chrNW_004936815:734,167...745,092
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Wnt5a
Wnt family member 5A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28726637
NCBI chrNW_004936473:6,031,627...6,052,211
Ensembl chrNW_004936473:6,029,976...6,052,159
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Il23a
interleukin 23 subunit alpha
severity
ISO
RGD
PMID:16157683
RGD:39457940
NCBI chrNW_004936646:743,630...745,998
Ensembl chrNW_004936646:743,688...745,836
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Irak3
interleukin 1 receptor associated kinase 3
severity
ISO
mRNA:increased expression:lung (mouse)
RGD
PMID:20864681 PMID:22729155
RGD:35316077 RGD:36049798
NCBI chrNW_004936545:4,233,353...4,284,324
Ensembl chrNW_004936545:4,233,358...4,282,806
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Lcn2
lipocalin 2
ameliorates exacerbates
ISO
protein:increased expression:lung protein:increased expression:serum
RGD
PMID:19342674 PMID:25234944 PMID:29633303
RGD:126725082 RGD:126725084 RGD:126725085
NCBI chrNW_004936487:15,721,752...15,725,396
Ensembl chrNW_004936487:15,721,684...15,728,221
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LOC101964975
interleukin-8
ISO
RGD
PMID:11207292
RGD:38549344
NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353
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Plac8
placenta associated 8
severity
ISO
RGD
PMID:17404296
RGD:40924563
NCBI chrNW_004936738:1,484,905...1,503,181
Ensembl chrNW_004936738:1,484,859...1,503,302
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Trem1
triggering receptor expressed on myeloid cells 1
disease_progression
ISO
RGD
PMID:24396044
RGD:126925976
NCBI chrNW_004936476:18,577,825...18,583,675
Ensembl chrNW_004936476:18,574,381...18,583,647
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Ada
adenosine deaminase
ISO
protein:increased expression:serum
RGD
PMID:9255891
RGD:5128857
NCBI chrNW_004936530:2,217,713...2,224,070
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Cx3cl1
C-X3-C motif chemokine ligand 1
ISO
RGD
PMID:16113250
RGD:4891897
NCBI chrNW_004936475:9,443,851...9,454,715
Ensembl chrNW_004936475:9,443,733...9,455,062
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Ifng
interferon gamma
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:11349020
NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452
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Il18
interleukin 18
ISO
RGD
PMID:11083766
RGD:4889865
NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189
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Nod1
nucleotide binding oligomerization domain containing 1
ISO
RGD
PMID:20685341
RGD:5131443
NCBI chrNW_004936478:6,717,354...6,768,293
Ensembl chrNW_004936478:6,715,245...6,768,372
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Nod2
nucleotide binding oligomerization domain containing 2
ISO
RGD
PMID:20685341
RGD:5131443
NCBI chrNW_004936475:3,708,069...3,742,845
Ensembl chrNW_004936475:3,713,362...3,745,982
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Tlr5
toll like receptor 5
susceptibility
ISO
ClinVar Annotator: match by term: Legionnaire disease, susceptibility to
ClinVar OMIM
PMID:14623910 PMID:16027372 PMID:23447684 PMID:25741868
NCBI chrNW_004936526:383,490...387,007
Ensembl chrNW_004936526:383,418...401,552
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Tnfrsf1a
TNF receptor superfamily member 1A
ISO
RGD
PMID:18838275
RGD:5131445
NCBI chrNW_004936709:1,407,327...1,421,448
Ensembl chrNW_004936709:1,407,278...1,421,921
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Tnfrsf1b
TNF receptor superfamily member 1B
ISO
RGD
PMID:18838275
RGD:5131445
NCBI chrNW_004936474:908,414...935,765
Ensembl chrNW_004936474:908,485...934,177
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Ada
adenosine deaminase
ISO
protein:increased expression:serum
RGD
PMID:9255891
RGD:5128857
NCBI chrNW_004936530:2,217,713...2,224,070
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Atp1b2
ATPase Na+/K+ transporting subunit beta 2
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936595:908,019...914,426
Ensembl chrNW_004936595:907,919...915,053
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Ccl5
C-C motif chemokine ligand 5
ISO
protein:increased secretion:lung, secretion (mouse)
RGD
PMID:18717637
RGD:4891914
NCBI chrNW_004936490:253,279...259,947
Ensembl chrNW_004936490:253,034...259,965
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Ccl8
C-C motif chemokine ligand 8
ISO
RGD
PMID:16988274
RGD:4892091
NCBI chrNW_004936538:805,273...806,715
Ensembl chrNW_004936538:805,259...806,695
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Clec5a
C-type lectin domain containing 5A
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936592:5,733,592...5,741,573
Ensembl chrNW_004936592:5,733,332...5,741,047
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Col3a1
collagen type III alpha 1 chain
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936506:8,886,494...8,923,921
Ensembl chrNW_004936506:8,886,494...8,923,930
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Col6a1
collagen type VI alpha 1 chain
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936778:515,600...530,828
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Col6a2
collagen type VI alpha 2 chain
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936778:394,985...430,070
Ensembl chrNW_004936778:394,953...430,113
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Crp
C-reactive protein
ISO
RGD
PMID:21426633
RGD:5131292
NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606
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Dnase1l3
deoxyribonuclease 1L3
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936473:8,430,235...8,495,170
Ensembl chrNW_004936473:8,430,231...8,457,469
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Fcer2
Fc fragment of IgE receptor II
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936588:4,717,010...4,724,664
Ensembl chrNW_004936588:4,719,447...4,724,664
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Flt1
fms related receptor tyrosine kinase 1
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936472:23,442,946...23,617,523
Ensembl chrNW_004936472:23,440,088...23,617,041
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Galc
galactosylceramidase
ISO
protein:increased expression:serum (human) protein:increased expression:serum (mouse) associated with Guillain-Barre syndrome; protein:increased expression:serum (human) associated with Guillain-Barre syndrome; protein:increased expression:Cerebrospinal fluid, serum (human)
RGD
PMID:12225900 PMID:27490360 PMID:29301655 PMID:30396892
RGD:38599168 RGD:38599169 RGD:38599171 RGD:38599172
NCBI chrNW_004936488:15,444,184...15,519,395
Ensembl chrNW_004936488:15,444,801...15,518,856
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Hdc
histidine decarboxylase
ISO
RGD
PMID:17158962
RGD:5143920
NCBI chrNW_004936471:12,303,802...12,324,613
Ensembl chrNW_004936471:12,304,130...12,324,570
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Htra3
HtrA serine peptidase 3
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936477:19,625,479...19,662,532
Ensembl chrNW_004936477:19,646,047...19,661,632
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Ifng
interferon gamma
ISO
mRNA:increased expression:lung:
RGD
PMID:7935058
RGD:10755754
NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452
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Il13
interleukin 13
ISO
protein:increased expression:serum
RGD
PMID:20416219
RGD:4145765
NCBI chrNW_004936647:2,529,933...2,532,503
Ensembl chrNW_004936647:2,530,491...2,532,373
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Il22ra2
interleukin 22 receptor subunit alpha 2
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936560:4,493,279...4,506,973
Ensembl chrNW_004936560:4,493,279...4,506,973
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Inhba
inhibin subunit beta A
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936478:16,878,725...16,884,065
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Ms4a1
membrane spanning 4-domains A1
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936581:2,466,294...2,477,530
Ensembl chrNW_004936581:2,466,312...2,477,530
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Pld4
phospholipase D family member 4
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936621:515,710...523,317
Ensembl chrNW_004936621:515,636...523,359
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Tcf7
transcription factor 7
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936647:1,096,726...1,125,753
Ensembl chrNW_004936647:1,097,019...1,125,729
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Tcl1a
TCL1 family AKT coactivator A
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936604:127,841...131,056
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Tnf
tumor necrosis factor
ISO
protein:increased expression:serum
RGD
PMID:20416219
RGD:4145765
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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Tnfrsf13c
TNF receptor superfamily member 13C
severity
ISO
RGD
PMID:28302172
RGD:32716376
NCBI chrNW_004936492:98,878...101,920
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Alox5
arachidonate 5-lipoxygenase
ISO
RGD
PMID:12773506
RGD:4890419
NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931
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Aicda
activation induced cytidine deaminase
ISO
RGD
PMID:26456931
RGD:11098923
NCBI chrNW_004936870:25,039...34,601
Ensembl chrNW_004936870:25,039...34,601
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Alox5
arachidonate 5-lipoxygenase
ISO
RGD
PMID:20231413
RGD:4890435
NCBI chrNW_004936554:7,807,914...7,848,691
Ensembl chrNW_004936554:7,808,355...7,867,931
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Btk
Bruton tyrosine kinase
ameliorates
ISO
RGD
PMID:30646846
RGD:124715470
NCBI chrNW_004936813:429,400...467,481
Ensembl chrNW_004936813:429,224...463,441
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C3
complement C3
disease_progression
ISO
protein:decreased expression:serum associated with Liver Cirrhosis, Experimental;protein:decreased expression:respiratory system fluid/secretion
RGD
PMID:20405 PMID:15972516 PMID:17956621
RGD:5129509 RGD:5129523 RGD:5130163
NCBI chrNW_004936588:3,985,732...4,023,221
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C5
complement C5
severity
ISO
RGD
PMID:7814608
RGD:5130159
NCBI chrNW_004936487:9,391,774...9,474,168
Ensembl chrNW_004936487:9,391,804...9,474,159
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Ccl5
C-C motif chemokine ligand 5
susceptibility
ISO
RGD
PMID:16455992
RGD:4892130
NCBI chrNW_004936490:253,279...259,947
Ensembl chrNW_004936490:253,034...259,965
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Cd14
CD14 molecule
ISO
RGD
PMID:17185649
RGD:4144788
NCBI chrNW_004936531:9,572,392...9,575,771
Ensembl chrNW_004936531:9,571,796...9,575,923
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Chi3l1
chitinase 3 like 1
ISO
protein:increased secretion:serum (human)
RGD
PMID:10515841
RGD:4892626
NCBI chrNW_004936567:1,411,080...1,418,332
Ensembl chrNW_004936567:1,411,037...1,418,801
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Crhr1
corticotropin releasing hormone receptor 1
ISO
RGD
PMID:21774994
RGD:5147472
NCBI chrNW_004936541:2,288,847...2,333,129
Ensembl chrNW_004936541:2,288,841...2,331,689
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Crhr2
corticotropin releasing hormone receptor 2
ISO
RGD
PMID:21774994
RGD:5147472
NCBI chrNW_004936478:6,901,098...6,947,719
Ensembl chrNW_004936478:6,899,017...6,947,790
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Crp
C-reactive protein
disease_progression
ISO
RGD
PMID:21281676
RGD:5131293
NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606
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Cxcl9
C-X-C motif chemokine ligand 9
ISO
protein:increased expression:lung
RGD
PMID:20381636
RGD:5135285
NCBI chrNW_004936676:33,580...40,323
Ensembl chrNW_004936676:32,128...40,329
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Hmox1
heme oxygenase 1
ISO
associated with influenza;protein:increased expression:lung
RGD
PMID:17348295
RGD:4145366
NCBI chrNW_004936492:5,042,353...5,049,216
Ensembl chrNW_004936492:5,042,330...5,049,311
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Il15
interleukin 15
ISO
protein:increased expression:alveolar macrophage, bronchial epithelial cell
RGD
PMID:17611121
RGD:5000755
NCBI chrNW_004936535:6,344,348...6,358,803
Ensembl chrNW_004936535:6,344,395...6,350,197
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Il15ra
interleukin 15 receptor subunit alpha
ISO
RGD
PMID:17611121
RGD:5000755
NCBI chrNW_004936484:8,590,945...8,623,478
Ensembl chrNW_004936484:8,590,482...8,623,469
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Il17a
interleukin 17A
ISO
RGD
PMID:19995896
RGD:4888531
NCBI chrNW_004936476:8,621,860...8,625,008
Ensembl chrNW_004936476:8,621,860...8,625,008
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Il18
interleukin 18
ISO
RGD
PMID:15770015
RGD:4889960
NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189
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Il6
interleukin 6
ISO
RGD
PMID:20643849
RGD:4143255
NCBI chrNW_004936549:7,015,595...7,016,246
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Lep
leptin
ISO
RGD
PMID:17822444
RGD:5128869
NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334
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Lepr
leptin receptor
ISO
RGD
PMID:21148797
RGD:5128846
NCBI chrNW_004936591:5,771,371...5,846,177
Ensembl chrNW_004936591:5,774,326...5,836,444
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LOC101964975
interleukin-8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24894820
NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353
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LOC101976500
haptoglobin
ISO
RGD
PMID:19396720
RGD:5147385
NCBI chrNW_004936475:21,841,054...21,845,821
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Mapk1
mitogen-activated protein kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24894820
NCBI chrNW_004936619:1,889,841...1,932,646
Ensembl chrNW_004936619:1,889,708...1,932,646
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Mapk3
mitogen-activated protein kinase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24894820
NCBI chrNW_004936501:12,342,670...12,390,650
Ensembl chrNW_004936501:12,384,804...12,392,180
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Masp2
MBL associated serine protease 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12904520
NCBI chrNW_004936474:100,584...113,781
Ensembl chrNW_004936474:101,402...114,313
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Nos2
nitric oxide synthase 2
ISO
RGD
PMID:17056580
RGD:4891950
NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051
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Pten
phosphatase and tensin homolog
ameliorates
ISO
myeloid knockout
RGD
PMID:20505137
RGD:127285597
NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323
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Sftpd
surfactant protein D
severity
ISO
RGD
PMID:16255775
RGD:4143519
NCBI chrNW_004936716:60,754...73,010
Ensembl chrNW_004936716:60,656...73,099
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Sirt1
sirtuin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24894820
NCBI chrNW_004936521:10,296,097...10,316,673
Ensembl chrNW_004936521:10,296,097...10,322,215
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Sting1
stimulator of interferon response cGAMP interactor 1
ISO
RGD
PMID:29263110
RGD:39128230
NCBI chrNW_004936531:8,555,966...8,562,829
Ensembl chrNW_004936531:8,555,637...8,562,885
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Tlr2
toll like receptor 2
ISO
RGD
PMID:19956717
RGD:4145321
NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788
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Tnf
tumor necrosis factor
ISO
associated with influenza;protein:increased expression:lung
RGD
PMID:9032201 PMID:17348295
RGD:4143479 RGD:4145366
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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Trem1
triggering receptor expressed on myeloid cells 1
ameliorates
ISO
RGD
PMID:19596984 PMID:24752755
RGD:126928121 RGD:127229903
NCBI chrNW_004936476:18,577,825...18,583,675
Ensembl chrNW_004936476:18,574,381...18,583,647
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Azin1
antizyme inhibitor 1
ISO
mRNA:increased expression:alveolar macrophage
RGD
PMID:19158080
RGD:14700806
NCBI chrNW_004936470:40,801,943...40,832,543
Ensembl chrNW_004936470:40,801,943...40,834,003
G
C3
complement C3
ISO
RGD
PMID:17169032
RGD:5129525
NCBI chrNW_004936588:3,985,732...4,023,221
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Cd40
CD40 molecule
treatment
ISO
RGD
PMID:10968950
RGD:8547797
NCBI chrNW_004936514:6,936,915...6,947,246
Ensembl chrNW_004936514:6,936,572...6,947,280
G
Csf2
colony stimulating factor 2
ISO
protein:increased expression:respiratory system fluid/secretion
RGD
PMID:19487471
RGD:5131475
NCBI chrNW_004936647:3,081,896...3,083,864
Ensembl chrNW_004936647:3,081,896...3,083,864
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Il23a
interleukin 23 subunit alpha
ISO
RGD
PMID:17403873
RGD:39458043
NCBI chrNW_004936646:743,630...745,998
Ensembl chrNW_004936646:743,688...745,836
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Il33
interleukin 33
treatment
ISO
RGD
PMID:21220696
RGD:40400892
NCBI chrNW_004936539:763,755...791,461
Ensembl chrNW_004936539:623,248...791,470
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Muc1
mucin 1, cell surface associated
ISO
protein:increased expression:serum
RGD
PMID:9617869
RGD:5131424
NCBI chrNW_004936580:4,691,870...4,694,092
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Nos2
nitric oxide synthase 2
ISO
protein:decreased dimerization:alveolar macrophage mRNA:increased expression:alveolar macrophage
RGD
PMID:20377877 PMID:20558778
RGD:4144112 RGD:4891486
NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051
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Sftpb
surfactant protein B
ISO
protein:decreased expression:lung
RGD
PMID:11385364
RGD:4143431
NCBI chrNW_004936712:1,614,979...1,621,207
Ensembl chrNW_004936712:1,614,979...1,622,466
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Sftpc
surfactant protein C
ISO
protein:decreased expression:lung
RGD
PMID:11385364
RGD:4143431
NCBI chrNW_004936555:5,966,610...5,982,083
Ensembl chrNW_004936555:5,979,417...5,982,011
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Sftpd
surfactant protein D
ISO
protein:increased expression:lung
RGD
PMID:11385364
RGD:4143431
NCBI chrNW_004936716:60,754...73,010
Ensembl chrNW_004936716:60,656...73,099
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Tlr2
toll like receptor 2
ISO
RGD
PMID:18400546
RGD:4145341
NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788
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Gc
GC vitamin D binding protein
ISO
protein:increased expression:bronchoalveolar fluid:
RGD
PMID:21136918
RGD:5509873
NCBI chrNW_004936598:3,220,029...3,256,091
Ensembl chrNW_004936598:3,219,991...3,261,629
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Akt1
AKT serine/threonine kinase 1
treatment
ISO
RGD
PMID:23613163
RGD:38676477
NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093
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Cd86
CD86 molecule
ISO
protein:decreased expression:spleen, plasmacytoid dendritic cell (mouse)
RGD
PMID:20949109
RGD:4892562
NCBI chrNW_004936536:8,414,491...8,481,712
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Cftr
CF transmembrane conductance regulator
ISO
RGD
PMID:28289144
RGD:36049750
NCBI chrNW_004936589:1,565,933...1,719,208
G
Csf3
colony stimulating factor 3
treatment
ISO
RGD
PMID:10228098
RGD:11039478
NCBI chrNW_004936490:15,142,526...15,146,375
Ensembl chrNW_004936490:15,142,808...15,144,487
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Fn1
fibronectin 1
ISO
RGD
PMID:12065530
RGD:7205474
NCBI chrNW_004936586:1,708,803...1,773,372
Ensembl chrNW_004936586:1,708,684...1,773,383
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Ifnar1
interferon alpha and beta receptor subunit 1
susceptibility
ISO
RGD
PMID:19603548
RGD:5490273
NCBI chrNW_004936500:8,953,809...8,975,261
Ensembl chrNW_004936500:8,953,049...8,973,978
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Il10
interleukin 10
ISO
mRNA, protein:increased expression:lung
RGD
PMID:22940620
RGD:7364825
NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502
G
Il15
interleukin 15
ISO
RGD
PMID:18390740
RGD:4996474
NCBI chrNW_004936535:6,344,348...6,358,803
Ensembl chrNW_004936535:6,344,395...6,350,197
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Il1b
interleukin 1 beta
ISO
RGD
PMID:20065029
RGD:4142828
NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165
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Il33
interleukin 33
ISO
mRNA:increased expression:lung:
RGD
PMID:28401938
RGD:40400699
NCBI chrNW_004936539:763,755...791,461
Ensembl chrNW_004936539:623,248...791,470
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Nod2
nucleotide binding oligomerization domain containing 2
ISO
RGD
PMID:20493961
RGD:5131444
NCBI chrNW_004936475:3,708,069...3,742,845
Ensembl chrNW_004936475:3,713,362...3,745,982
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Prkn
parkin RBR E3 ubiquitin protein ligase
ISO
protein:increased expression:lung (mouse)
RGD
PMID:28663335
RGD:13432209
NCBI chrNW_004936489:12,118,538...12,913,664
Ensembl chrNW_004936489:12,120,678...13,327,872
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Ptpn11
protein tyrosine phosphatase non-receptor type 11
severity
ISO
mRNA:increased expression:lung associated with influenza
RGD
PMID:31782850
RGD:39131288
NCBI chrNW_004936668:2,602,261...2,687,903
Ensembl chrNW_004936668:2,628,706...2,682,448
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Ripk3
receptor interacting serine/threonine kinase 3
treatment
ISO
RGD
PMID:25445964
RGD:127229910
NCBI chrNW_004936722:209,019...212,817
Ensembl chrNW_004936722:209,013...212,839
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Sftpb
surfactant protein B
ameliorates
ISO
RGD
PMID:20007532
RGD:151667448
NCBI chrNW_004936712:1,614,979...1,621,207
Ensembl chrNW_004936712:1,614,979...1,622,466
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Atm
ATM serine/threonine kinase
exacerbates
ISO
RGD
PMID:27421701
RGD:126779562
NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211
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Btk
Bruton tyrosine kinase
ISO
RGD
PMID:30873567
RGD:124715473
NCBI chrNW_004936813:429,400...467,481
Ensembl chrNW_004936813:429,224...463,441
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Ido1
indoleamine 2,3-dioxygenase 1
ISO
mRNA:increased expression:lung (mouse)
RGD
PMID:20385761
RGD:39938865
NCBI chrNW_004936843:658,058...672,662
Ensembl chrNW_004936843:657,979...672,700
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Ifng
interferon gamma
ISO
protein:increased expression:lung,natural killer cell (mouse)
RGD
PMID:21887255
RGD:40818252
NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452
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Il6
interleukin 6
ISO
protein:increased expression:lung,natural killer cell (mouse)
RGD
PMID:21887255
RGD:40818252
NCBI chrNW_004936549:7,015,595...7,016,246
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Irak3
interleukin 1 receptor associated kinase 3
severity
ISO
RGD
PMID:22492852
RGD:35316076
NCBI chrNW_004936545:4,233,353...4,284,324
Ensembl chrNW_004936545:4,233,358...4,282,806
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Itgb2
integrin subunit beta 2
susceptibility
ISO
RGD
PMID:11390487
RGD:127345090
NCBI chrNW_004936778:1,286,475...1,311,184
Ensembl chrNW_004936778:1,286,341...1,311,194
G
Lamp1
lysosomal associated membrane protein 1
ISO
protein:increased expression:lung, natural killer cell (mouse)
RGD
PMID:21887255
RGD:40818252
NCBI chrNW_004936472:377,359...389,121
Ensembl chrNW_004936472:378,173...389,381
G
Marco
macrophage receptor with collagenous structure
exacerbates
ISO
RGD
PMID:15263032
RGD:41412189
NCBI chrNW_004936469:51,323,746...51,366,551
G
Pdcd1
programmed cell death 1
treatment
ISO
RGD
PMID:25624454
RGD:40818422
NCBI chrNW_004936745:152,571...163,712
Ensembl chrNW_004936745:152,612...161,587
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Pik3cd
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
treatment
ISO
associated with immunodeficiency 14
RGD
PMID:30093657
RGD:40890269
NCBI chrNW_004936623:3,672,201...3,696,959
G
Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
severity
ISO
RGD
PMID:17322108
RGD:38599154
NCBI chrNW_004936479:17,084,006...17,112,264
Ensembl chrNW_004936479:17,084,920...17,112,258
G
Ripk3
receptor interacting serine/threonine kinase 3
exacerbates
ISO
RGD
PMID:33625952
RGD:127229925
NCBI chrNW_004936722:209,019...212,817
Ensembl chrNW_004936722:209,013...212,839
G
Tnf
tumor necrosis factor
ISO
protein:increased expression:lung,natural killer cell (mouse)
RGD
PMID:21887255
RGD:40818252
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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Cd68
CD68 molecule
ISO
mRNA:increased expression:lung,trachea (mouse)
RGD
PMID:12581500
RGD:40925942
NCBI chrNW_004936595:858,289...861,131
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Cxcl10
C-X-C motif chemokine ligand 10
ISO
RGD
PMID:17655904
RGD:5135437
NCBI chrNW_004936676:60,869...63,028
Ensembl chrNW_004936676:60,621...63,106
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Cxcl16
C-X-C motif chemokine ligand 16
ISO
mRNA:decreased expression:bronchoalveolar lavage (human)
RGD
PMID:32407669
RGD:30296672
NCBI chrNW_004936677:3,157,173...3,162,599
Ensembl chrNW_004936677:3,157,144...3,163,210
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Cxcl9
C-X-C motif chemokine ligand 9
ISO
RGD
PMID:17655904
RGD:5135437
NCBI chrNW_004936676:33,580...40,323
Ensembl chrNW_004936676:32,128...40,329
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Fgf10
fibroblast growth factor 10
treatment
ISO
RGD
PMID:27322618
RGD:127284849
NCBI chrNW_004936480:18,114,231...18,195,884
Ensembl chrNW_004936480:18,114,204...18,195,898
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Fgfr2
fibroblast growth factor receptor 2
ISO
protein:increased expression:epithelial stem/progenitor cells (mouse)
RGD
PMID:27322618
RGD:127284849
NCBI chrNW_004936486:10,506,680...10,606,272
Ensembl chrNW_004936486:10,507,097...10,602,019
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Hmox1
heme oxygenase 1
ISO
mRNA:increased expression:lung
RGD
PMID:8843786
RGD:4145417
NCBI chrNW_004936492:5,042,353...5,049,216
Ensembl chrNW_004936492:5,042,330...5,049,311
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Ifnar1
interferon alpha and beta receptor subunit 1
disease_progression
ISO
RGD
PMID:21383977
RGD:5490272
NCBI chrNW_004936500:8,953,809...8,975,261
Ensembl chrNW_004936500:8,953,049...8,973,978
G
Il10
interleukin 10
treatment
ISO
RGD
PMID:25219125
RGD:10450576
NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502
G
Il15
interleukin 15
ISO
RGD
PMID:20335267
RGD:4892670
NCBI chrNW_004936535:6,344,348...6,358,803
Ensembl chrNW_004936535:6,344,395...6,350,197
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Il17ra
interleukin 17 receptor A
ISO
mRNA:decreased expression:bronchoalveolar lavage (human)
RGD
PMID:32407669
RGD:30296672
NCBI chrNW_004936807:143,165...165,820
G
Il1b
interleukin 1 beta
ISO
mRNA:increased expression:bronchoalveolar lavage (human)
RGD
PMID:32407669
RGD:30296672
NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165
G
Il1rn
interleukin 1 receptor antagonist
ISO
mRNA:increased expression:bronchoalveolar lavage (human)
RGD
PMID:32407669
RGD:30296672
NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340
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Il4r
interleukin 4 receptor
ISO
mRNA:decreased expression:bronchoalveolar lavage (human)
RGD
PMID:32407669
RGD:30296672
NCBI chrNW_004936501:11,025,590...11,058,807
Ensembl chrNW_004936501:11,025,567...11,058,818
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LOC101964209
C-C chemokine receptor type 1
ISO
RGD
PMID:15254170
RGD:5688163
NCBI chrNW_004936596:177,774...183,186
Ensembl chrNW_004936596:177,812...183,186
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LOC101964975
interleukin-8
ISO
mRNA:increased expression:bronchoalveolar lavage (human)
RGD
PMID:32407669
RGD:30296672
NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353
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LOC101968920
eotaxin
ISO
RGD
PMID:20644177
RGD:4140459
NCBI chrNW_004936538:835,436...848,907
Ensembl chrNW_004936538:835,859...837,710 Ensembl chrNW_004936538:835,859...837,710
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LOC101968921
angiotensin-converting enzyme
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15381116
NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177
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Mif
macrophage migration inhibitory factor
ISO
RGD
PMID:19941385
RGD:4891005
NCBI chrNW_004936619:1,207,058...1,208,010
Ensembl chrNW_004936619:1,203,746...1,208,442
G
Tnf
tumor necrosis factor
treatment
ISO
RGD
PMID:25219125
RGD:10450576
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all