Tfpi (tissue factor pathway inhibitor)

Gene: Tfpi (tissue factor pathway inhibitor) Ictidomys tridecemlineatus

Analyze

Symbol:

Tfpi

Name:

tissue factor pathway inhibitor

RGD ID:

12716378

Description:

ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN cellular response to interleukin-1 (ortholog); cellular response to lipopolysaccharide (ortholog); response to estradiol (ortholog); PARTICIPATES IN coagulation cascade pathway; syndecan signaling pathway; ASSOCIATED WITH Airway Obstruction (ortholog); atrial fibrillation (ortholog); B-lymphoblastic leukemia/lymphoma (ortholog); FOUND IN extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tissue factor pathway inhibitor, transcript variant X1; tissue factor pathway inhibitor, transcript variant X2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	146,663,997 - 146,734,969 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936506	10,103,139 - 10,171,863 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936506	10,103,120 - 10,172,800 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Airway Obstruction (ISO)

atrial fibrillation (ISO)

B-lymphoblastic leukemia/lymphoma (ISO)

Burns (ISO)

diabetes mellitus (ISO)

disease of cellular proliferation (ISO)

disseminated intravascular coagulation (ISO)

Embolism and Thrombosis (ISO)

Endotoxemia (ISO)

factor V deficiency (ISO)

factor VIII deficiency (ISO)

familial hyperlipidemia (ISO)

Femur Head Necrosis (ISO)

Fetal Death (ISO)

genetic disease (ISO)

graft-versus-host disease (ISO)

Hypoxia (ISO)

idiopathic pulmonary fibrosis (ISO)

juvenile rheumatoid arthritis (ISO)

Kidney Reperfusion Injury (ISO)

leukemia (ISO)

liver cirrhosis (ISO)

Liver Injury (ISO)

Liver Reperfusion Injury (ISO)

myocardial infarction (ISO)

Neointima (ISO)

nephrotic syndrome (ISO)

Neurodevelopmental Disorders (ISO)

ovarian hyperstimulation syndrome (ISO)

pre-eclampsia (ISO)

Pregnancy-Induced Hypertension (ISO)

preterm premature rupture of the membranes (ISO)

protein S deficiency (ISO)

pulmonary fibrosis (ISO)

Sepsis (ISO)

systemic lupus erythematosus (ISO)

thrombophilia due to activated protein C resistance (ISO)

thrombotic thrombocytopenic purpura (ISO)

toxic shock syndrome (ISO)

transient cerebral ischemia (ISO)

Venous Thromboembolism (ISO)

Venous Thrombosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blood coagulation (IEA)

cellular response to interleukin-1 (ISO)

cellular response to lipopolysaccharide (ISO)

cellular response to steroid hormone stimulus (IEA)

negative regulation of blood coagulation (IEA)

response to estradiol (ISO)

response to lipopolysaccharide (ISO)

Cellular Component

caveola (IEA)

cell surface (IEA)

extracellular region (IEA)

extracellular space (IEA,ISO)

membrane (IEA)

Molecular Function

serine-type endopeptidase inhibitor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

coagulation cascade pathway (ISO)

syndecan signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Tfpi
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	146,663,997 - 146,734,969 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936506	10,103,139 - 10,171,863 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936506	10,103,120 - 10,172,800 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TFPI
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	187,464,230 - 187,554,435 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	187,464,230 - 187,565,760 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	188,328,957 - 188,419,162 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	188,037,202 - 188,127,464 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	188,156,790 - 188,244,556	NCBI
Celera	2	181,925,068 - 182,015,356 (-)	NCBI		Celera
Cytogenetic Map	2	q32.1	NCBI
HuRef	2	180,188,532 - 180,278,959 (-)	NCBI		HuRef
CHM1_1	2	188,334,627 - 188,424,881 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	187,953,180 - 188,043,364 (-)	NCBI		T2T-CHM13v2.0

Tfpi
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	84,263,199 - 84,307,119 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	84,263,199 - 84,307,119 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	84,432,855 - 84,476,775 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	84,432,855 - 84,476,775 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	84,273,017 - 84,316,932 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	84,233,699 - 84,275,013 (-)	NCBI		MGSCv36	mm8
Celera	2	86,041,007 - 86,084,914 (-)	NCBI		Celera
Cytogenetic Map	2	D	NCBI
cM Map	2	49.41	NCBI

Tfpi
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	89,939,862 - 89,989,253 (-)	NCBI		GRCr8
mRatBN7.2	3	69,533,156 - 69,582,547 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	69,533,156 - 69,576,880 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	72,915,327 - 72,959,162 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	81,513,992 - 81,557,826 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	79,267,881 - 79,311,569 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	71,852,738 - 71,902,127 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	71,852,744 - 71,893,618 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	78,373,808 - 78,423,115 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	67,654,389 - 67,697,178 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	67,550,760 - 67,593,550 (-)	NCBI
Celera	3	68,890,124 - 68,933,788 (-)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

Tfpi
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	10,924,893 - 11,004,284 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	10,925,155 - 11,004,229 (+)	NCBI	ChiLan1.0	ChiLan1.0

TFPI
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	90,129,678 - 90,219,981 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	90,144,776 - 90,234,979 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	74,744,154 - 74,834,338 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	192,541,881 - 192,631,867 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	192,541,881 - 192,581,384 (-)	Ensembl	panpan1.1		panPan2

TFPI
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	36	29,457,131 - 29,546,455 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	36	29,459,371 - 29,511,310 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	36	29,358,584 - 29,410,512 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	36	29,680,362 - 29,769,683 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	36	29,680,366 - 29,734,666 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	36	29,744,554 - 29,796,457 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	36	29,679,616 - 29,731,462 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	36	29,848,287 - 29,900,234 (-)	NCBI		UU_Cfam_GSD_1.0

TFPI
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	92,345,075 - 92,409,905 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	92,345,083 - 92,409,962 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	102,535,224 - 102,694,356 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TFPI
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	73,004,762 - 73,105,772 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	73,002,522 - 73,105,858 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	126,397,666 - 126,498,612 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tfpi
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624899	2,406,282 - 2,473,883 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624899	2,401,861 - 2,473,762 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005324392	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013358209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040294566	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040294567	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000010151 ⟹ ENSSTOP00000009105

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936506	10,103,139 - 10,171,863 (+)	Ensembl

RefSeq Acc Id:

ENSSTOT00000028528 ⟹ ENSSTOP00000021705

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936506	10,103,139 - 10,160,868 (+)	Ensembl

RefSeq Acc Id:

XM_005324392 ⟹ XP_005324449

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	146,663,997 - 146,734,966 (-)	NCBI
SpeTri2.0	NW_004936506	10,103,120 - 10,172,800 (+)	NCBI

Sequence:

show sequence

CAGACTCCAAGGCTCCCTCTCTCTTCCTAAACACACAGTGACTTTGGGCTGGATAATTCTCCAA
TTTACCTCACTCTTTCCCTGCTAGCAGGATCAGATTGCATTTCTTTCAGTATTCTCCACTTCCC
ACTTTCTTGATCTGTTTAAAAGAAGTGAAGAAGTTAAGTCCTCTTTTCAATACCTGGAAGGGAA
AACAAAATAGCCTCAAGTCCGTTTTGAAAAAATCTTTCCAAGAACTTTCGTCAGAGATTTTACT
CAGACGATTTATGCAATGAAGAAAGAACGCATATTTTGGGCTTCTGTATGTCTGCTGCTTAGTC
TTGCCCCTATGCCTCTTAATGCTGTTCCTGAGGAAGATGAAGAACATACAAATATCACAGATAC
TGAGTTGCCACCACTGAAATTGATGCATTCATTTTGTGCATTGAAGGCAGATGATGGGCCATGC
AAAGCTATGATGAAGAGATTTTTTTTCAATATTTTCACTCAGCAATGTGAAGAATTTGTATATG
GGGGCTGTGAAGGAAATCAGAATCGATTTGAAAGTCTGGAAGAGTGCAAAGAAAAATGTGCAGT
TGGTTATCCAAAGAAGATATCAAAGAAGACATTTAAAAAAGAAAAGCCAGATTTCTGCTTTTTG
GAGGAAGATGCTGGAATCTGTAGAGGTTATATTACCAGGTATTTTTATAGCAATCAGTCGAAGC
AATGTGAGCGTTTCAAGTACGGTGGGTGCCTGGGCAATCCAAACAACTTTGAATCGTTGGAAGA
ATGCAGGAACACCTGTGAGGATGTTTTGAATGATTTCCAGGTGGATGATTATAGAAAGCAGCTT
GATGCTATAAACAATATCTCTGTGACTTCCCAACCTACCAAAGTTCCCAGCCTTTGGGAATTTC
ATGGTCCCTCATGGTGTCTCACCCCAGCAGACAGAGGACTGTGTCAAGCCAGTGAAAAGAGATA
CTACTTTAATTCAGTCATTGGGAAATGCCGCCCATTTAAGTACAGTGGATGTGGCGGAAATGAA
AATAATTTTACTTCTAAAAGAGCATGTATTAGGTCATGTAAAAAAGGTTTCATCCAAAGAATAT
CAAAAGAAGGACTAATTAAAACAAAAAGAAAAAGGAAGAAGCAGCCAGTAAAAATACTATTTGA
AGAAGTTTTTGTTAAAAATATATAAATATTATACTATGAAAGCATTAATTCTACTAAATATTTT
ATACAAAGCATTTCACTATGGCTTCTATTTTCCCCTTTGCTAACATATTGTTAATGGACCTGTT
AATTAAGTAATTTTCTAGTCTTATACCTGCTATTAATCCATTTGTATCAGAATTCCTCTTCTAA
TCTGGTTGAATTTCTTATTCTAGGTACAATTTATTAACTAGCTAATGTGAATTTATTCTATAAC
TTGAGCCCTAACTATTCCTCATTTAACTACAAATTATCATACTACTAATCACATAAACTTAGAT
TTTTCCCTCAGTTTATGACCATCTATTTGAGAATATGTTTGCACTTATTTGTAACAATCATGTA
TGAGTGATATCTTTTATAGTCTATGACCAGATTCAGAAATGCAGTTATTAAAGAACAAGCAAAC
CTTTGGGTTTCACATATAAAATGGTTTTAAAACACCTGATTCTGATAAAGATCACTCAACTGAG
CATTGAGAAATCACCAATAATAATACAATTCTGTCCTGTGCTTCCATTCATTGGCATGGCTTAT
TCACCTTTTGCACCTATCAGTACCTTCATCAATAGTGAGCCAAGCTGTCTTTGAACAAAGAACA
GTACACTGCATAATTTGCCTGCCTGATTTTGATTGGCTTAAAATTTCTTTTGTCTATGACCCAT
TCTATCAGTAAAATAGTTGAATAATCATGTGTTAAATACACTTCATGTGATAAAACTTTATGGA
AAAGGAAAGTTCTAATGGCTAACACAGGAATTTTTTGTATGTACTTCCTAATCTTATAACTTGA
TAAACTGTTCTCTCACCCAAAATAGTGAGAATTTGAAACCTGTATTTAGTCATTAGGTTTTGCA
CACAGTGTAACCAATAACTAATGCTCAAAAAAAGCTATTTTTGTGGCAGGAAAATTATTGGCAA
AAAAGAA

hide sequence

RefSeq Acc Id:

XM_013358209 ⟹ XP_013213663

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	146,676,024 - 146,734,969 (-)	NCBI
SpeTri2.0	NW_004936506	10,103,120 - 10,163,413 (+)	NCBI

Sequence:

show sequence

CAGACTCCAAGGCTCCCTCTCTCTTCCTAAACACACAGTGACTTTGGGCTGGATAATTCTCCAA
TTTACCTCACTCTTTCCCTGCTAGCAGGATCAGATTGCATTTCTTTCAGTATTCTCCACTTCCC
ACTTTCTTGATCTGTTTAAAAGAAGTGAAGAAGTTAAGTCCTCTTTTCAATACCTGGAAGGGAA
AACAAAATAGCCTCAAGTCCGTTTTGAAAAAATCTTTCCAAGAACTTTCGTCAGAGATTTTACT
CAGACGATTTATGCAATGAAGAAAGAACGCATATTTTGGGCTTCTGTATGTCTGCTGCTTAGTC
TTGCCCCTATGCCTCTTAATGCTGTTCCTGAGGAAGATGAAGAACATACAAATATCACAGATAC
TGAGTTGCCACCACTGAAATTGATGCATTCATTTTGTGCATTGAAGGCAGATGATGGGCCATGC
AAAGCTATGATGAAGAGATTTTTTTTCAATATTTTCACTCAGCAATGTGAAGAATTTGTATATG
GGGGCTGTGAAGGAAATCAGAATCGATTTGAAAGTCTGGAAGAGTGCAAAGAAAAATGTGCAGT
TGGTTATCCAAAGAAGATATCAAAGAAGACATTTAAAAAAGAAAAGCCAGATTTCTGCTTTTTG
GAGGAAGATGCTGGAATCTGTAGAGGTTATATTACCAGGTATTTTTATAGCAATCAGTCGAAGC
AATGTGAGCGTTTCAAGTACGGTGGGTGCCTGGGCAATCCAAACAACTTTGAATCGTTGGAAGA
ATGCAGGAACACCTGTGAGGATGTTTTGAATGATTTCCAGGTGGATGATTATAGAAAGCAGCTT
GATGCTATAAACAATATCTCTGTGACTTCCCAACCTACCAAAGTTCCCAGCCTTTGGGTTACAA
AAGAAAGAACAAATGATGGTTGGAAGAAAGCTGATCATACTTACCAAGTCTTTCTGATCACCTT
CTGCATTTATGTATCCATGTCCTTATTAGCATTGGATAGCATTTTATGAATATGTTAATATTTG
GGCTTTTGACATTTATTAATATTTATATAGTATCTATGATGTCTTTGATAGCATGCCATTAATA
AAGTTTTAACATTTGCATGCATAGTTAATATAGTCCTCCCACTATCTTACTGGTAAATTACTAA
CTAGCACAGAACAACTAATATTCTTAAGTATTCATATCCGTTCTGGGCCTTTGGGGTGGACCTG
ACCATTCATGGAAAAAGTGAGTTATTTTCCCAATTCTCACAGCCCCCTTTGCTTCTATACATCA
ACTCTTAACAGCTGCCTTGGGACTACATCAACTTTATGATATTTTGGAAAAAATCATCTTTGGG
TAGACTTCAAAAGCCTGCTGCCAACCCAGTCTCTGGCACTTGCTCCCTGACTGAGGAAAGGAAC
ACCTACCTACTTCATCCAGGGCCACATTGATCCATGCCAGCCACCAAGTCAAGGGAGAATGATT
GGATGTCATGTTGAAGACCATTTTTGCTACCTGAAACTCCCTCTCTTGCCTGACTATATTCGAT
GTATGATCTAGCGGCCAGATATCATATATGTGTGGGGAAAAATGACATAGAAAGAAAATAAAAG
CATATACATATATTCATATATAAAAATACATTAAAATTGTTTTTGATTATCATTGGCCTTCTGG
AAGAAGATTATGCTGATAAAGAACCTAATCAAAAGCCAAATACCAGCACTGATAGAGTTGATTC
ACAGATTTGCAACAGAATATTCCCACATACTTGGCCTTTTCTTGTGAAGATGTGACTGATTACA
TGTAGAGGAATGCACAACCATTTTGGGGGAAGAAAACACCCCCAAAGAGTTACACGTTCATCTG
TATATCCCAGCAATCATGAGCATGTGGACAATTCAGAAAAAAACCCGTTTCACCACAACCCACC
TACAATTCCAAAGGAGGATCCTGCTTTTCAAATACATTCGTTCTCAAATCAAGAAGCATAAAAA
CATCCCTCATAATCTCAATATGCCCGCATAATAAATCTGGTGCCTCCTGCTGAATCTGGCAAGA
CAACTTTCCAAAAATAGAAAATCCTTTGGAGAGCATCCATCAGGACTTCTGCTTTCTGGCAGGA
GTGCTGGTAAAAAAAAAAACCAAAAATGTAGCACTTCATCTCTGCCAAAATTGAAGCCATCCAA
ATGCTATCACCCTAGGTGACCACTGCCTGTCTTTCTAACCTCTTTCTTCCTGGACCATCTTGAG
TCCAACCAAAGATATGTTTTTGTCCCAGTTAGTCCTCCAGAAAAGAGTTTCTCAACCTGAATAT
ACTTTTAAACAAGAAAAGAAGAACTTTACAGCTTCTAAAGTGTAAACTCCTAAAGTTATAAACT
ATTATACAACTATTATTATTATTTATTAACCAAAATTTATTTACAGAGTAATACAATCCAAACT
ACTAGAAAATAAATTACTACTACTAATTTGATAAGACATGTTCTGCCAAAAAGTGAGAGAGAGA
GAGAGAGAGAGAGAGAGAGAGAGAGAGAAATCCTCATTGTAATATAAATTTAGTATAGTATTGG
TGGCAACAGGGCAGGTTATGATTGAGATAGGAATAGTTTAGAAAAGTTCACGTGACTCTGTTGT
GTGTAATTCTCTGAATGCCATTTTTCTACTTGAATGCAGGAGTGAATTTGAGAAGCACTGATAT
AAAACCTGTTCGTTCGGAAAATCCCAACTCTACATTTTATAGGGACACCATGGAGTGGTGTTTC
TAGCTTTCATTCATAGCTAATGCTATAAAATAGATCAGTTTGACTGGTGGAGATATGATCACAG
AGGCCATAAAAGCCTGGAACTTTTGGTCTGTTATCTAGAGTCAGTCCAGATTGAACATGCCAAT
ATAAAGTTCTTGCCTTCAAACACTGGAACACTCCAGTTGGCTCAGTGCAGTCATCCCCAAGACT
TGTTCCCCATCGCCTTGTTTGGAGATCTATTTTAATTATTTATCTTTCTCCTGTTCAAACTTGA
TAACCTCCAATCCAGGCATGTGACTATGAGTAAGACACATCTAGGACACTGTAGACTCTTCAGT
GAAGAGGCAATTTGTGGATCAGATATGAGTCAGAAATTATACCAACTTTCTCTTTAGCTGAAAA
AAAATCATTAAAACGTGTTTGTTGAGTTAAATTTTTTTTAATTTTCAGATTAGTTCTCTGAATA
ACATATAGTGCTTAAGAACACTGACTTTATAGACAAAGATGTGTTTTTAAATTCCAGTTCTTAT
TTCTCCACTTGCTCTGTGACCTTAAAAAAAAAAAATCATACAACTTCGCTCAGGCTCAAGTTAC
TCATTGATTATAAGTGGATATTTGTAAATATTTTAATAATACAAACATTTTAATCCCATGTTTC
ACACAAAAAAAGAACTCAGAAGTATTAATTTTTGAGGTTGTGTTTGATGATATTGATAATGATA
ATCATGATCTAGTTCCATCTCAGGCTTATAGCAGAAAAAGAAATAACATAATGAAGGAGTATTA
CGTGAAAATGTTATTTATAATTTTAATATAAAAAATCT

hide sequence

RefSeq Acc Id:

XM_040294566 ⟹ XP_040150500

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	146,663,997 - 146,699,006 (-)	NCBI

RefSeq Acc Id:

XM_040294567 ⟹ XP_040150501

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	146,663,997 - 146,699,007 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005324449	(Get FASTA)	NCBI Sequence Viewer
	XP_013213663	(Get FASTA)	NCBI Sequence Viewer
	XP_040150500	(Get FASTA)	NCBI Sequence Viewer
	XP_040150501	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000009105.3
	ENSSTOP00000021705.2
GenBank Protein	KAG3274845	(Get FASTA)	NCBI Sequence Viewer
	KAG3274846	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005324449 ⟸ XM_005324392
- Peptide Label:	isoform X1
- UniProtKB:	I3MEX6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKKERIFWASVCLLLSLAPMPLNAVPEEDEEHTNITDTELPPLKLMHSFCALKADDGPCKAMMK RFFFNIFTQQCEEFVYGGCEGNQNRFESLEECKEKCAVGYPKKISKKTFKKEKPDFCFLEEDAG ICRGYITRYFYSNQSKQCERFKYGGCLGNPNNFESLEECRNTCEDVLNDFQVDDYRKQLDAINN ISVTSQPTKVPSLWEFHGPSWCLTPADRGLCQASEKRYYFNSVIGKCRPFKYSGCGGNENNFTS KRACIRSCKKGFIQRISKEGLIKTKRKRKKQPVKILFEEVFVKNI hide sequence

RefSeq Acc Id:	XP_013213663 ⟸ XM_013358209
- Peptide Label:	isoform X2
- UniProtKB:	I3NBF8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKKERIFWASVCLLLSLAPMPLNAVPEEDEEHTNITDTELPPLKLMHSFCALKADDGPCKAMMK RFFFNIFTQQCEEFVYGGCEGNQNRFESLEECKEKCAVGYPKKISKKTFKKEKPDFCFLEEDAG ICRGYITRYFYSNQSKQCERFKYGGCLGNPNNFESLEECRNTCEDVLNDFQVDDYRKQLDAINN ISVTSQPTKVPSLWVTKERTNDGWKKADHTYQVFLITFCIYVSMSLLALDSIL hide sequence

RefSeq Acc Id:	XP_040150501 ⟸ XM_040294567
- Peptide Label:	isoform X1
- UniProtKB:	I3MEX6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040150500 ⟸ XM_040294566
- Peptide Label:	isoform X1
- UniProtKB:	I3MEX6 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000021705 ⟸ ENSSTOT00000028528

RefSeq Acc Id:

ENSSTOP00000009105 ⟸ ENSSTOT00000010151

Protein Domains

BPTI/Kunitz inhibitor

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000010154	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000010151.3	UniProtKB/TrEMBL
	ENSSTOT00000028528.2	UniProtKB/TrEMBL
Gene3D-CATH	4.10.410.10	UniProtKB/TrEMBL
InterPro	Kunitz_BPTI	UniProtKB/TrEMBL
	Kunitz_BPTI_sf	UniProtKB/TrEMBL
	Prtase_inh_Kunz-CS	UniProtKB/TrEMBL
	TFPI-like	UniProtKB/TrEMBL
NCBI Gene	Tfpi	ENTREZGENE
PANTHER	KUNITZ-TYPE PROTEASE INHIBITOR-RELATED	UniProtKB/TrEMBL
	PROTEIN CBG23496	UniProtKB/TrEMBL
	TISSUE FACTOR PATHWAY INHIBITOR	UniProtKB/TrEMBL
Pfam	Kunitz_BPTI	UniProtKB/TrEMBL
PIRSF	TFPI	UniProtKB/TrEMBL
PRINTS	BASICPTASE	UniProtKB/TrEMBL
PROSITE	BPTI_KUNITZ_1	UniProtKB/TrEMBL
	BPTI_KUNITZ_2	UniProtKB/TrEMBL
SMART	SM00131	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57362	UniProtKB/TrEMBL
UniProt	I3MEX6	ENTREZGENE, UniProtKB/TrEMBL
	I3NBF8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Annotations - PID (archival)