Keap1 (kelch like ECH associated protein 1)

Gene: Keap1 (kelch like ECH associated protein 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Keap1

Name:

kelch like ECH associated protein 1

RGD ID:

12660576

Description:

ENCODES a protein that exhibits disordered domain specific binding (inferred); identical protein binding (inferred); RNA polymerase II-specific DNA-binding transcription factor binding (inferred); INVOLVED IN cellular response to carbohydrate stimulus (ortholog); cellular response to interleukin-4 (ortholog); cellular response to organic cyclic compound (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; ASSOCIATED WITH Alcoholic Liver Diseases (ortholog); amyotrophic lateral sclerosis (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN adherens junction (ortholog); focal adhesion (ortholog); protein-containing complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

kelch-like ECH-associated protein 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	209,560,465 - 209,569,647 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936659	782,340 - 793,688 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936659	785,059 - 793,775 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alcoholic Liver Diseases (ISO)

amyotrophic lateral sclerosis (ISO)

Chemical and Drug Induced Liver Injury (ISO)

Chronic Hepatitis B (ISO)

Diabetic Nephropathies (ISO)

diabetic retinopathy (ISO)

Disease Progression (ISO)

end stage renal disease (ISO)

Endotoxemia (ISO)

extrahepatic cholestasis (ISO)

gallbladder cancer (ISO)

Gallbladder Neoplasms (ISO)

gastrointestinal system disease (ISO)

genetic disease (ISO)

head and neck squamous cell carcinoma (ISO)

Hepatic Insufficiency (ISO)

hepatitis (ISO)

Hepatomegaly (ISO)

idiopathic interstitial pneumonia (ISO)

keratosis (ISO)

lung non-small cell carcinoma (ISO)

primary biliary cholangitis (ISO)

Prostatic Neoplasms (ISO)

pulmonary emphysema (ISO)

renal cell carcinoma (ISO)

Reperfusion Injury (ISO)

Sepsis (ISO)

steatotic liver disease (ISO)

transient cerebral ischemia (ISO)

ureteral obstruction (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to carbohydrate stimulus (ISO)

cellular response to interleukin-4 (IEA,ISO)

cellular response to organic cyclic compound (ISO)

cellular response to oxidative stress (IEA)

cytoplasmic sequestering of transcription factor (ISO)

in utero embryonic development (IEA,ISO)

negative regulation of gene expression (ISO)

negative regulation of response to oxidative stress (IEA)

protein ubiquitination (IEA)

regulation of autophagy (IEA)

regulation of DNA-templated transcription (IEA,ISO)

regulation of epidermal cell differentiation (IEA,ISO)

response to immobilization stress (ISO)

response to metal ion (ISO)

response to thyroid hormone (ISO)

selenium compound metabolic process (ISO)

ubiquitin-dependent protein catabolic process (IEA)

Cellular Component

actin filament (IEA)

adherens junction (ISO)

centriolar satellite (IEA)

Cul3-RING ubiquitin ligase complex (IEA)

cytoplasm (IEA)

cytosol (IEA)

endoplasmic reticulum (IEA)

focal adhesion (ISO)

inclusion body (IEA)

midbody (IEA)

nucleoplasm (IEA)

nucleus (IEA)

protein-containing complex (IEA,ISO)

Molecular Function

disordered domain specific binding (IEA)

identical protein binding (IEA)

protein binding (ISO)

RNA polymerase II-specific DNA-binding transcription factor binding (IEA)

ubiquitin-like ligase-substrate adaptor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

nuclear factor, erythroid 2 like 2 signaling pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Keap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	209,560,465 - 209,569,647 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936659	782,340 - 793,688 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936659	785,059 - 793,775 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KEAP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	10,486,125 - 10,503,356 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	10,486,125 - 10,503,558 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	10,596,801 - 10,614,032 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	10,457,796 - 10,475,054 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	10,491,509 - 10,508,764 (-)	NCBI		Celera
Cytogenetic Map	19	p13.2	NCBI
HuRef	19	10,176,101 - 10,192,927 (-)	NCBI		HuRef
CHM1_1	19	10,597,575 - 10,614,823 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	10,612,569 - 10,629,791 (-)	NCBI		T2T-CHM13v2.0

Keap1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	21,141,026 - 21,150,628 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	21,141,026 - 21,150,657 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	21,229,730 - 21,239,332 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	21,229,730 - 21,239,361 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	21,034,174 - 21,043,776 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	20,980,469 - 20,989,215 (-)	NCBI		MGSCv36	mm8
Celera	9	18,498,845 - 18,508,447 (-)	NCBI		Celera
Cytogenetic Map	9	A3	NCBI
cM Map	9	7.74	NCBI

Keap1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	28,044,555 - 28,054,042 (-)	NCBI		GRCr8
mRatBN7.2	8	19,768,375 - 19,777,862 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	19,768,375 - 19,777,862 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	23,787,814 - 23,797,272 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	22,085,659 - 22,095,117 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	19,998,059 - 20,007,547 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	22,250,518 - 22,259,868 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	22,250,518 - 22,259,779 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	22,305,765 - 22,315,026 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	20,259,178 - 20,266,351 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	20,259,177 - 20,266,352 (-)	NCBI
Celera	8	21,161,976 - 21,171,435 (-)	NCBI		Celera
Cytogenetic Map	8	q13	NCBI

Keap1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	1,704,695 - 1,711,290 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	1,704,695 - 1,711,339 (-)	NCBI	ChiLan1.0	ChiLan1.0

KEAP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	15,404,143 - 15,421,611 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	14,402,746 - 14,420,092 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	10,037,544 - 10,055,091 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	10,701,298 - 10,717,664 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	10,701,303 - 10,717,604 (-)	Ensembl	panpan1.1		panPan2

KEAP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	50,651,070 - 50,661,178 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	50,650,711 - 50,658,496 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	50,523,052 - 50,533,206 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	51,174,558 - 51,182,077 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	51,164,570 - 51,185,490 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	50,380,711 - 50,390,863 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	50,808,833 - 50,818,993 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	51,049,891 - 51,060,051 (+)	NCBI		UU_Cfam_GSD_1.0

KEAP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	69,276,336 - 69,294,382 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	69,280,940 - 69,290,267 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	69,634,153 - 69,643,610 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KEAP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	9,515,789 - 9,526,699 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	9,515,416 - 9,522,797 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	10,471,467 - 10,484,386 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Keap1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	2,580,861 - 2,595,275 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	2,580,812 - 2,595,023 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005336128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005336129	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040290464	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000010107 ⟹ ENSSTOP00000009067

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936659	782,340 - 793,688 (-)	Ensembl

RefSeq Acc Id:

XM_005336128 ⟹ XP_005336185

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	209,560,916 - 209,569,647 (+)	NCBI
SpeTri2.0	NW_004936659	785,059 - 793,775 (-)	NCBI

Sequence:

show sequence

TCCCCCCGGCGCGCAGCGATGGAGGCGCCCGGGCCCGGGCGGCGGAGGCGGAGCCCGAGCGCGG
CCATGGCGGGGCCCCTGACTGCCAGCGGTGGTATTGCCCCTTGTCACCTGGAACCCCATGCAGC
CAGAACCTGGGCCTAGCAGGGCTGGGGCCTGCAGCCGATTCCTGCCCCTGTGTTCACAGTGCCC
CAAGGGGGCAGGGGACGCGGTGATGTACGCTTCCACTGAGTGCAAGGCTGAGGTGACACCCTCC
CAGCATGGCAACCGCACCTTCAGCTACACGCTGGAGGATCACACCAAACAGGCCTTCGGCATCA
TGAATGAACTGCGGCTCAGCCAGCAGCTCTGCGACGTCACGCTGCAAGTCAAGTACAAGGACAT
CCCGGCTGCCCAGTTTATGGCCCACAAGGTGGTGCTGGCCTCATCTAGCCCTGTCTTCAAGGCC
ATGTTCACTAACGGGCTTCGGGAGCAGGGCATGGAGGTGGTGTCCATCGAGGGCATCCACCCCC
AGGTCATGGAGCGGCTCATCGAGTTCGCCTACACAGCTTCCATCTCCATGGGTGAGAAGTGTGT
GCTCCACGTCATGAACGGCGCGGTCATGTACCAGATCGACAGTGTGGTCCGCGCCTGCAGCGAC
TTCCTGGTGCAGCAGCTGGACCCCAGCAATGCCATTGGCATTGCCAACTTTGCCGAGCAGATTG
GCTGTGCTGAACTGCATCAGCGGGCCCGGGAGTACATCTACATGCACTTTGGGGAGGTGGCCAA
GCAAGAGGAGTTCTTCAACCTGTCCCACTGCCAGCTGGTGACTCTCATCAGCCGGGATGATCTG
AACGTGCGCTGCGAGTCCGAGGTCTTCCATGCCTGCATCAACTGGGTCAAATACGACTGTGAGC
AGCGCCGCTTCTACGTGCAGGCGCTGCTGCGCGCGGTGCGCTGTCACTCGCTCACACCCCACTT
TCTGCAAATGCAGTTGCAGAAGTGCGAGATCCTGCAGTCGGACTCGCGCTGTAAGGACTACCTG
GTCAAGATCTTCCAGGAGCTCACGCTGCACAAACCCACGCAGGTGATGCCCTGCCGGGCGCCCA
AGGTCGGCAGGCTCATCTACACGGCGGGCGGCTACTTCCGACAATCCCTCAGCTACCTGGAGGC
CTACAACCCCAGCGATGGCACTTGGCTGAGGCTGGCCGACCTGCAGGTTCCACGGAGTGGCCTG
GCGGGTTGTGTGGTGGGTGGGCTGCTGTACGCCGTGGGCGGCCGAAACAATTCTCCCGATGGCA
ACACCGACTCGAACGCTCTCGACTGCTACAATCCCATGACCAACCAGTGGTCGCCCTGTGCCCC
CATGAGCGTGCCTCGCAACCGCATCGGGGTTGGGGTCATCGACGGGCACATCTATGCAGTCGGA
GGCTCCCACGGCTGCATTCACCACAACAGTGTGGAGAGGTATGAGCCCGAGCGTGATGAGTGGC
ACTTGGTGTCCCCAATGCTGACTCGGAGGATCGGGGTGGGTGTAGCTGTTCTCAATCGCCTGCT
CTATGCCGTCGGGGGCTTTGATGGGACGAACCGCCTTAATTCAGCCGAGTGTTACTATCCCGAG
AGGAACGAGTGGCGAATGATCACCCCCATGAACACCATCCGAAGTGGGGCAGGAGTCTGCGTCT
TGCACAACCGTATCTATGCCGCCGGGGGCTACGATGGTCAGGACCAGCTTAACAGCGTGGAGCG
TTTTGATGTGGAGACAGAAACATGGACTTTTGTAGCCCCCATGAAGCATCGTCGAAGTGCCCTG
GGGATTACTGTGCACCAGGGGAGAATCTACGTCCTGGGAGGCTATGATGGTCACACGTTCCTGG
ACAGTGTGGAGTGCTACGACCCAGACACAGACACCTGGAGTGAGGTGACTCGAATGACATCGGG
CCGGAGCGGGGTGGGCGTAGCTGTCACCATGGAACCCTGCCGCAAACAGATCGACCAGCAGAAC
TGTACCTGTTGAAGCACTTTTGTTGTTTGGGGGAGAAAAGAAAGCATTGTATTCATACCCAACA
ACAAAGAGGAGGTTACGGAGTGGATACTCAGCCTCCAGGAAAGGAGGCTGGATGCCTCCATATC
CAAATGACACCGCTCCAGCAGACCAGAGTGGGAACCCACAAGCCCTCCCTATAGCCCAGGAGTG
TCCATCCAAGACAGACCTCTTGGGAGGGGAGTAGGAAGGGCATGCTCCCAGGTGAGGTCCCACC
GCCACTTGGGAGGGACTAGGATACTACCAGCTGCCACCTCCCCTTGGGGTGAAAACAAGTGCCA
GATCAGACTGGCTTTTGTTTCCTGCATCTTTGCAGTTGGTTCCCAGAGACCTCTAAGGGGCCAA
GTGAGGCCACAGGGGCCGAGGTCCCTCAGGAAGTGTCCCCAGGGATGGGCCTGTACATAAAAGC
CACTGGGTTTCTCTGCCCTGGACAGTCATTTTGTTGATAAGTAACCCTGTAACTTTCCAATGAG
AATAAAGAACAAACTAACTAGTGTCTTCCA

hide sequence

RefSeq Acc Id:

XM_040290464 ⟹ XP_040146398

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	209,560,465 - 209,569,647 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005336185	(Get FASTA)	NCBI Sequence Viewer
	XP_040146398	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000009067.2

RefSeq Acc Id:

XP_005336185 ⟸ XM_005336128

- UniProtKB:

I3MEU7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQPEPGPSRAGACSRFLPLCSQCPKGAGDAVMYASTECKAEVTPSQHGNRTFSYTLEDHTKQAF
GIMNELRLSQQLCDVTLQVKYKDIPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGI
HPQVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAE
QIGCAELHQRAREYIYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYD
CEQRRFYVQALLRAVRCHSLTPHFLQMQLQKCEILQSDSRCKDYLVKIFQELTLHKPTQVMPCR
APKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSP
DGNTDSNALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERD
EWHLVSPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGV
CVLHNRIYAAGGYDGQDQLNSVERFDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHT
FLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQQNCTC

hide sequence

RefSeq Acc Id:	XP_040146398 ⟸ XM_040290464
- UniProtKB:	I3MEU7 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000009067 ⟸ ENSSTOT00000010107

Protein Domains

BTB

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000010114	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000010107.3	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.420	UniProtKB/TrEMBL
	2.120.10.80	UniProtKB/TrEMBL
InterPro	BACK	UniProtKB/TrEMBL
	BTB-kelch_protein	UniProtKB/TrEMBL
	BTB/POZ_dom	UniProtKB/TrEMBL
	KEAP1	UniProtKB/TrEMBL
	KEAP1_BACK	UniProtKB/TrEMBL
	Kelch-typ_b-propeller	UniProtKB/TrEMBL
	Kelch_1	UniProtKB/TrEMBL
	SKP1/BTB/POZ_sf	UniProtKB/TrEMBL
NCBI Gene	Keap1	ENTREZGENE
PANTHER	ACTIN-BINDING PROTEIN IPP	UniProtKB/TrEMBL
	KELCH PROTEIN	UniProtKB/TrEMBL
Pfam	BACK	UniProtKB/TrEMBL
	BTB	UniProtKB/TrEMBL
	Kelch_1	UniProtKB/TrEMBL
PIRSF	Kelch-like_protein_gigaxonin	UniProtKB/TrEMBL
PROSITE	BTB	UniProtKB/TrEMBL
SMART	BACK	UniProtKB/TrEMBL
	BTB	UniProtKB/TrEMBL
	Kelch	UniProtKB/TrEMBL
Superfamily-SCOP	SSF117281	UniProtKB/TrEMBL
	SSF54695	UniProtKB/TrEMBL
UniProt	I3MEU7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations