ONTOLOGY REPORT - ANNOTATIONS
| Term: | rel-(3R,5S)-fluvastatin |
|
| Accession: | CHEBI:38561
|
browse the term
|
| Synonyms: | exact_synonym: | rel-(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid |
| | related_synonym: | (3R,5S,6E)-rel-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoic acid; C24H26FNO4; Cranoc; fluvastatin |
| | xref_casrn: | 93957-54-1 |
| | xref: | Beilstein:9168031 "Beilstein Registry Number"; ChemIDplus:93957-54-1 "CAS Registry Number" |
| | xref_mesh: | MESH:C065180 |
|
|
rel-(3R,5S)-fluvastatin
|
| G |
Abca1 |
ATP-binding cassette, subfamily A (ABC1), member 1 |
|
multiple interactions |
ISO |
5 |
70,493,357 |
70,583,729 |
RGD:6480464 |
CTD |
| G |
Abcb11 |
ATP-binding cassette, subfamily B (MDR/TAP), member 11 |
|
decreases activity |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcb11 |
ATP-binding cassette, subfamily B (MDR/TAP), member 11 |
|
multiple interactions |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcb11 |
ATP-binding cassette, subfamily B (MDR/TAP), member 11 |
|
multiple interactions |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcc2 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 2 |
|
affects transport |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Apob |
apolipoprotein B |
|
multiple interactions |
ISO |
6 |
31,508,060 |
31,548,083 |
RGD:6480464 |
CTD |
| G |
Apob |
apolipoprotein B |
|
multiple interactions |
ISO |
6 |
31,508,060 |
31,548,083 |
RGD:6480464 |
CTD |
| G |
Apoe |
apolipoprotein E |
|
multiple interactions |
ISO |
1 |
79,003,634 |
79,006,387 |
RGD:6480464 |
CTD |
| G |
Apoe |
apolipoprotein E |
|
increases expression |
ISO |
1 |
79,003,634 |
79,006,387 |
RGD:6480464 |
CTD |
| G |
Arhgap29 |
Rho GTPase activating protein 29 |
|
multiple interactions |
ISO |
2 |
218,619,428 |
218,679,087 |
RGD:6480464 |
CTD |
| G |
Arhgef12 |
Rho guanine nucleotide exchange factor (GEF) 12 |
|
multiple interactions |
ISO |
8 |
45,984,042 |
46,106,412 |
RGD:6480464 |
CTD |
| G |
Arhgef3 |
Rho guanine nucleotide exchange factor (GEF) 3 |
|
multiple interactions |
ISO |
16 |
2,595,636 |
2,665,051 |
RGD:6480464 |
CTD |
| G |
Bcap29 |
B-cell receptor-associated protein 29 |
|
multiple interactions |
ISO |
6 |
49,464,362 |
49,504,424 |
RGD:6480464 |
CTD |
| G |
Bcl2l11 |
BCL2-like 11 (apoptosis facilitator) |
|
multiple interactions |
ISO |
3 |
115,692,323 |
115,722,701 |
RGD:6480464 |
CTD |
| G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
|
multiple interactions |
ISO |
4 |
144,139,486 |
144,145,186 |
RGD:6480464 |
CTD |
| G |
Bub1 |
BUB1 mitotic checkpoint serine/threonine kinase |
|
multiple interactions |
ISO |
3 |
115,323,510 |
115,354,906 |
RGD:6480464 |
CTD |
| G |
Casp1 |
caspase 1 |
|
multiple interactions |
ISO |
8 |
2,027,976 |
2,036,872 |
RGD:6480464 |
CTD |
| G |
Ccl2 |
chemokine (C-C motif) ligand 2 |
|
multiple interactions |
EXP |
10 |
70,256,263 |
70,258,061 |
RGD:6480464 |
CTD |
| G |
Cdk2ap2 |
cyclin-dependent kinase 2 associated protein 2 |
|
multiple interactions |
ISO |
1 |
206,681,430 |
206,683,098 |
RGD:6480464 |
CTD |
| G |
Cks2 |
CDC28 protein kinase regulatory subunit 2 |
|
multiple interactions |
ISO |
17 |
19,423,502 |
19,429,451 |
RGD:6480464 |
CTD |
| G |
Cyp2b2 |
cytochrome P450, family 2, subfamily b, polypeptide 2 |
|
increases expression |
ISO |
1 |
81,345,425 |
81,359,415 |
RGD:6480464 |
CTD |
| G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
|
multiple interactions |
ISO |
1 |
243,281,320 |
243,320,945 |
RGD:6480464 |
CTD |
| G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
|
multiple interactions |
ISO |
12 |
9,517,016 |
9,541,000 |
RGD:6480464 |
CTD |
| G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
|
decreases activity |
ISO |
12 |
9,517,016 |
9,541,000 |
RGD:6480464 |
CTD |
| G |
Emp3 |
epithelial membrane protein 3 |
|
multiple interactions |
ISO |
1 |
96,389,783 |
96,392,960 |
RGD:6480464 |
CTD |
| G |
Ercc5 |
excision repair cross-complementing rodent repair deficiency, complementation group 5 |
|
multiple interactions |
ISO |
9 |
43,248,023 |
43,293,196 |
RGD:6480464 |
CTD |
| G |
Erg |
v-ets erythroblastosis virus E26 oncogene homolog (avian) |
|
multiple interactions |
ISO |
11 |
35,655,563 |
35,760,055 |
RGD:6480464 |
CTD |
| G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
|
multiple interactions |
ISO |
15 |
42,425,336 |
42,453,390 |
RGD:6480464 |
CTD |
| G |
Fnta |
farnesyltransferase, CAAX box, alpha |
|
multiple interactions |
ISO |
16 |
70,440,340 |
70,458,433 |
RGD:6480464 |
CTD |
| G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
|
multiple interactions |
ISO |
7 |
10,289,073 |
10,291,102 |
RGD:6480464 |
CTD |
| G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
|
multiple interactions |
ISO |
2 |
27,127,504 |
27,149,580 |
RGD:6480464 |
CTD |
| G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
|
decreases activity |
ISO |
2 |
27,127,504 |
27,149,580 |
RGD:6480464 |
CTD |
| G |
Igf1 |
insulin-like growth factor 1 |
|
multiple interactions |
ISO |
7 |
24,531,669 |
24,605,742 |
RGD:6480464 |
CTD |
| G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
|
multiple interactions |
ISO |
9 |
72,003,637 |
72,016,263 |
RGD:6480464 |
CTD |
| G |
Il10ra |
interleukin 10 receptor, alpha |
|
multiple interactions |
ISO |
8 |
48,211,040 |
48,224,439 |
RGD:6480464 |
CTD |
| G |
Il2rg |
interleukin 2 receptor, gamma |
|
multiple interactions |
ISO |
X |
89,342,055 |
89,345,715 |
RGD:6480464 |
CTD |
| G |
Ldlr |
low density lipoprotein receptor |
|
multiple interactions |
ISO |
8 |
20,824,040 |
20,846,920 |
RGD:6480464 |
CTD |
| G |
Ldlr |
low density lipoprotein receptor |
|
multiple interactions |
ISO |
8 |
20,824,040 |
20,846,920 |
RGD:6480464 |
CTD |
| G |
Ldlr |
low density lipoprotein receptor |
|
increases activity |
ISO |
8 |
20,824,040 |
20,846,920 |
RGD:6480464 |
CTD |
| G |
Lipc |
lipase, hepatic |
|
multiple interactions |
ISO |
8 |
75,323,442 |
75,450,353 |
RGD:6480464 |
CTD |
| G |
Lmna |
lamin A/C |
|
decreases farnesylation |
ISO |
2 |
180,595,724 |
180,616,354 |
RGD:6480464 |
CTD |
| G |
Lpl |
lipoprotein lipase |
|
multiple interactions |
ISO |
16 |
22,533,105 |
22,556,905 |
RGD:6480464 |
CTD |
| G |
Lzts1 |
leucine zipper, putative tumor suppressor 1 |
|
multiple interactions |
ISO |
16 |
22,243,137 |
22,300,978 |
RGD:6480464 |
CTD |
| G |
Mcl1 |
myeloid cell leukemia sequence 1 |
|
decreases expression |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Med23 |
mediator complex subunit 23 |
|
multiple interactions |
ISO |
1 |
21,013,168 |
21,060,313 |
RGD:6480464 |
CTD |
| G |
Mphosph8 |
M-phase phosphoprotein 8 |
|
multiple interactions |
ISO |
15 |
35,667,102 |
35,694,910 |
RGD:6480464 |
CTD |
| G |
Mpp5 |
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
|
multiple interactions |
ISO |
6 |
101,414,657 |
101,471,504 |
RGD:6480464 |
CTD |
| G |
Ndc80 |
NDC80 kinetochore complex component |
|
multiple interactions |
ISO |
9 |
110,702,935 |
110,718,894 |
RGD:6480464 |
CTD |
| G |
Nphs1 |
nephrosis 1, congenital, Finnish type (nephrin) |
|
multiple interactions |
EXP |
1 |
85,414,492 |
85,444,233 |
RGD:6480464 |
CTD |
| G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
|
increases activity |
ISO |
11 |
64,239,918 |
64,276,702 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
increases activity |
ISO |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
increases activity |
EXP |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
increases activity |
ISO |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Optn |
optineurin |
|
multiple interactions |
ISO |
17 |
84,298,122 |
84,348,330 |
RGD:6480464 |
CTD |
| G |
Pcsk9 |
proprotein convertase subtilisin/kexin type 9 |
|
multiple interactions |
ISO |
5 |
127,501,476 |
127,524,289 |
RGD:6480464 |
CTD |
| G |
Pon1 |
paraoxonase 1 |
|
multiple interactions |
EXP |
4 |
29,936,314 |
29,964,821 |
RGD:6480464 |
CTD |
| G |
Pon1 |
paraoxonase 1 |
|
decreases activity |
EXP |
4 |
29,936,314 |
29,964,821 |
RGD:6480464 |
CTD |
| G |
Ppara |
peroxisome proliferator activated receptor alpha |
|
multiple interactions |
ISO |
7 |
123,729,774 |
123,807,090 |
RGD:6480464 |
CTD |
| G |
Ppp1r12a |
protein phosphatase 1, regulatory subunit 12A |
|
multiple interactions |
EXP |
7 |
46,876,552 |
46,986,022 |
RGD:6480464 |
CTD |
| G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
|
multiple interactions |
ISO |
1 |
95,994,023 |
95,997,080 |
RGD:6480464 |
CTD |
| G |
Prdx3 |
peroxiredoxin 3 |
|
multiple interactions |
ISO |
1 |
267,468,371 |
267,481,273 |
RGD:6480464 |
CTD |
| G |
Procr |
protein C receptor, endothelial |
|
increases expression |
ISO |
3 |
146,268,567 |
146,273,718 |
RGD:6480464 |
CTD |
| G |
Rab27b |
RAB27B, member RAS oncogene family |
|
multiple interactions |
ISO |
18 |
66,682,627 |
66,747,813 |
RGD:6480464 |
CTD |
| G |
Rab32 |
RAB32, member RAS oncogene family |
|
multiple interactions |
ISO |
1 |
5,203,908 |
5,218,416 |
RGD:6480464 |
CTD |
| G |
Rab5b |
RAB5B, member RAS oncogene family |
|
multiple interactions |
ISO |
7 |
1,979,776 |
1,998,540 |
RGD:6480464 |
CTD |
| G |
Rabgap1l |
RAB GTPase activating protein 1-like |
|
multiple interactions |
ISO |
13 |
75,685,603 |
76,275,726 |
RGD:6480464 |
CTD |
| G |
Rap1a |
RAP1A, member of RAS oncogene family |
|
decreases prenylation |
ISO |
2 |
200,980,324 |
201,001,561 |
RGD:6480464 |
CTD |
| G |
Rb1 |
retinoblastoma 1 |
|
decreases phosphorylation |
ISO |
15 |
53,828,881 |
53,962,099 |
RGD:6480464 |
CTD |
| G |
Rgs11 |
regulator of G-protein signaling 11 |
|
multiple interactions |
ISO |
10 |
15,469,922 |
15,478,157 |
RGD:6480464 |
CTD |
| G |
Rhoa |
ras homolog family member A |
|
multiple interactions |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Rhoa |
ras homolog family member A |
|
multiple interactions |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Rhob |
ras homolog family member B |
|
multiple interactions |
ISO |
6 |
32,052,333 |
32,054,507 |
RGD:6480464 |
CTD |
| G |
Rims2 |
regulating synaptic membrane exocytosis 2 |
|
multiple interactions |
ISO |
7 |
74,757,003 |
75,271,771 |
RGD:6480464 |
CTD |
| G |
Rin2 |
Ras and Rab interactor 2 |
|
multiple interactions |
ISO |
3 |
134,307,538 |
134,503,915 |
RGD:6480464 |
CTD |
| G |
Rxra |
retinoid X receptor alpha |
|
multiple interactions |
ISO |
3 |
6,605,782 |
6,689,224 |
RGD:6480464 |
CTD |
| G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
|
affects expression |
EXP |
1 |
23,501,257 |
23,506,651 |
RGD:6480464 |
CTD |
| G |
Slc15a1 |
solute carrier family 15 (oligopeptide transporter), member 1 |
|
decreases activity |
ISO |
15 |
106,549,586 |
106,592,594 |
RGD:6480464 |
CTD |
| G |
Slco1b3 |
solute carrier organic anion transporter family, member 1b3 |
|
affects import |
ISO |
4 |
179,045,586 |
179,118,680 |
RGD:6480464 |
CTD |
| G |
Slco2b1 |
solute carrier organic anion transporter family, member 2b1 |
|
affects import |
ISO |
1 |
156,992,492 |
157,028,887 |
RGD:6480464 |
CTD |
| G |
Sod2 |
superoxide dismutase 2, mitochondrial |
|
multiple interactions |
ISO |
1 |
41,862,997 |
41,870,327 |
RGD:6480464 |
CTD |
| G |
Sos2 |
son of sevenless homolog 2 (Drosophila) |
|
multiple interactions |
ISO |
6 |
91,609,463 |
91,722,481 |
RGD:6480464 |
CTD |
| G |
Spin2a |
spindlin family, member 2A |
|
multiple interactions |
ISO |
X |
37,609,279 |
37,610,330 |
RGD:6480464 |
CTD |
| G |
Spp1 |
secreted phosphoprotein 1 |
|
multiple interactions |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Tfpi |
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
|
increases expression |
ISO |
3 |
67,654,389 |
67,697,178 |
RGD:6480464 |
CTD |
| G |
Tgfb1 |
transforming growth factor, beta 1 |
|
affects expression |
EXP |
1 |
80,894,705 |
80,911,020 |
RGD:6480464 |
CTD |
| G |
Tp53inp1 |
tumor protein p53 inducible nuclear protein 1 |
|
multiple interactions |
ISO |
5 |
25,008,253 |
25,014,263 |
RGD:6480464 |
CTD |
| G |
Vim |
vimentin |
|
multiple interactions |
EXP |
17 |
87,847,280 |
87,855,763 |
RGD:6480464 |
CTD |
| G |
Wnt11 |
wingless-type MMTV integration site family, member 11 |
|
multiple interactions |
ISO |
1 |
156,125,969 |
156,142,065 |
RGD:6480464 |
CTD |
(3S,5R)-fluvastatin
|
| G |
Abca1 |
ATP-binding cassette, subfamily A (ABC1), member 1 |
|
multiple interactions |
ISO |
5 |
70,493,357 |
70,583,729 |
RGD:6480464 |
CTD |
| G |
Abcb11 |
ATP-binding cassette, subfamily B (MDR/TAP), member 11 |
|
decreases activity |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcb11 |
ATP-binding cassette, subfamily B (MDR/TAP), member 11 |
|
multiple interactions |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcb11 |
ATP-binding cassette, subfamily B (MDR/TAP), member 11 |
|
multiple interactions |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Abcc2 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 2 |
|
affects transport |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Apob |
apolipoprotein B |
|
multiple interactions |
ISO |
6 |
31,508,060 |
31,548,083 |
RGD:6480464 |
CTD |
| G |
Apob |
apolipoprotein B |
|
multiple interactions |
ISO |
6 |
31,508,060 |
31,548,083 |
RGD:6480464 |
CTD |
| G |
Apoe |
apolipoprotein E |
|
multiple interactions |
ISO |
1 |
79,003,634 |
79,006,387 |
RGD:6480464 |
CTD |
| G |
Apoe |
apolipoprotein E |
|
increases expression |
ISO |
1 |
79,003,634 |
79,006,387 |
RGD:6480464 |
CTD |
| G |
Arhgap29 |
Rho GTPase activating protein 29 |
|
multiple interactions |
ISO |
2 |
218,619,428 |
218,679,087 |
RGD:6480464 |
CTD |
| G |
Arhgef12 |
Rho guanine nucleotide exchange factor (GEF) 12 |
|
multiple interactions |
ISO |
8 |
45,984,042 |
46,106,412 |
RGD:6480464 |
CTD |
| G |
Arhgef3 |
Rho guanine nucleotide exchange factor (GEF) 3 |
|
multiple interactions |
ISO |
16 |
2,595,636 |
2,665,051 |
RGD:6480464 |
CTD |
| G |
Bcap29 |
B-cell receptor-associated protein 29 |
|
multiple interactions |
ISO |
6 |
49,464,362 |
49,504,424 |
RGD:6480464 |
CTD |
| G |
Bcl2l11 |
BCL2-like 11 (apoptosis facilitator) |
|
multiple interactions |
ISO |
3 |
115,692,323 |
115,722,701 |
RGD:6480464 |
CTD |
| G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
|
multiple interactions |
ISO |
4 |
144,139,486 |
144,145,186 |
RGD:6480464 |
CTD |
| G |
Bub1 |
BUB1 mitotic checkpoint serine/threonine kinase |
|
multiple interactions |
ISO |
3 |
115,323,510 |
115,354,906 |
RGD:6480464 |
CTD |
| G |
Casp1 |
caspase 1 |
|
multiple interactions |
ISO |
8 |
2,027,976 |
2,036,872 |
RGD:6480464 |
CTD |
| G |
Ccl2 |
chemokine (C-C motif) ligand 2 |
|
multiple interactions |
EXP |
10 |
70,256,263 |
70,258,061 |
RGD:6480464 |
CTD |
| G |
Cdk2ap2 |
cyclin-dependent kinase 2 associated protein 2 |
|
multiple interactions |
ISO |
1 |
206,681,430 |
206,683,098 |
RGD:6480464 |
CTD |
| G |
Cks2 |
CDC28 protein kinase regulatory subunit 2 |
|
multiple interactions |
ISO |
17 |
19,423,502 |
19,429,451 |
RGD:6480464 |
CTD |
| G |
Cyp2b2 |
cytochrome P450, family 2, subfamily b, polypeptide 2 |
|
increases expression |
ISO |
1 |
81,345,425 |
81,359,415 |
RGD:6480464 |
CTD |
| G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
|
multiple interactions |
ISO |
1 |
243,281,320 |
243,320,945 |
RGD:6480464 |
CTD |
| G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
|
multiple interactions |
ISO |
12 |
9,517,016 |
9,541,000 |
RGD:6480464 |
CTD |
| G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
|
decreases activity |
ISO |
12 |
9,517,016 |
9,541,000 |
RGD:6480464 |
CTD |
| G |
Emp3 |
epithelial membrane protein 3 |
|
multiple interactions |
ISO |
1 |
96,389,783 |
96,392,960 |
RGD:6480464 |
CTD |
| G |
Ercc5 |
excision repair cross-complementing rodent repair deficiency, complementation group 5 |
|
multiple interactions |
ISO |
9 |
43,248,023 |
43,293,196 |
RGD:6480464 |
CTD |
| G |
Erg |
v-ets erythroblastosis virus E26 oncogene homolog (avian) |
|
multiple interactions |
ISO |
11 |
35,655,563 |
35,760,055 |
RGD:6480464 |
CTD |
| G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
|
multiple interactions |
ISO |
15 |
42,425,336 |
42,453,390 |
RGD:6480464 |
CTD |
| G |
Fnta |
farnesyltransferase, CAAX box, alpha |
|
multiple interactions |
ISO |
16 |
70,440,340 |
70,458,433 |
RGD:6480464 |
CTD |
| G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
|
multiple interactions |
ISO |
7 |
10,289,073 |
10,291,102 |
RGD:6480464 |
CTD |
| G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
|
multiple interactions |
ISO |
2 |
27,127,504 |
27,149,580 |
RGD:6480464 |
CTD |
| G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
|
decreases activity |
ISO |
2 |
27,127,504 |
27,149,580 |
RGD:6480464 |
CTD |
| G |
Igf1 |
insulin-like growth factor 1 |
|
multiple interactions |
ISO |
7 |
24,531,669 |
24,605,742 |
RGD:6480464 |
CTD |
| G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
|
multiple interactions |
ISO |
9 |
72,003,637 |
72,016,263 |
RGD:6480464 |
CTD |
| G |
Il10ra |
interleukin 10 receptor, alpha |
|
multiple interactions |
ISO |
8 |
48,211,040 |
48,224,439 |
RGD:6480464 |
CTD |
| G |
Il2rg |
interleukin 2 receptor, gamma |
|
multiple interactions |
ISO |
X |
89,342,055 |
89,345,715 |
RGD:6480464 |
CTD |
| G |
Ldlr |
low density lipoprotein receptor |
|
multiple interactions |
ISO |
8 |
20,824,040 |
20,846,920 |
RGD:6480464 |
CTD |
| G |
Ldlr |
low density lipoprotein receptor |
|
multiple interactions |
ISO |
8 |
20,824,040 |
20,846,920 |
RGD:6480464 |
CTD |
| G |
Ldlr |
low density lipoprotein receptor |
|
increases activity |
ISO |
8 |
20,824,040 |
20,846,920 |
RGD:6480464 |
CTD |
| G |
Lipc |
lipase, hepatic |
|
multiple interactions |
ISO |
8 |
75,323,442 |
75,450,353 |
RGD:6480464 |
CTD |
| G |
Lmna |
lamin A/C |
|
decreases farnesylation |
ISO |
2 |
180,595,724 |
180,616,354 |
RGD:6480464 |
CTD |
| G |
Lpl |
lipoprotein lipase |
|
multiple interactions |
ISO |
16 |
22,533,105 |
22,556,905 |
RGD:6480464 |
CTD |
| G |
Lzts1 |
leucine zipper, putative tumor suppressor 1 |
|
multiple interactions |
ISO |
16 |
22,243,137 |
22,300,978 |
RGD:6480464 |
CTD |
| G |
Mcl1 |
myeloid cell leukemia sequence 1 |
|
decreases expression |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Med23 |
mediator complex subunit 23 |
|
multiple interactions |
ISO |
1 |
21,013,168 |
21,060,313 |
RGD:6480464 |
CTD |
| G |
Mphosph8 |
M-phase phosphoprotein 8 |
|
multiple interactions |
ISO |
15 |
35,667,102 |
35,694,910 |
RGD:6480464 |
CTD |
| G |
Mpp5 |
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
|
multiple interactions |
ISO |
6 |
101,414,657 |
101,471,504 |
RGD:6480464 |
CTD |
| G |
Ndc80 |
NDC80 kinetochore complex component |
|
multiple interactions |
ISO |
9 |
110,702,935 |
110,718,894 |
RGD:6480464 |
CTD |
| G |
Nphs1 |
nephrosis 1, congenital, Finnish type (nephrin) |
|
multiple interactions |
EXP |
1 |
85,414,492 |
85,444,233 |
RGD:6480464 |
CTD |
| G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
|
increases activity |
ISO |
11 |
64,239,918 |
64,276,702 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
increases activity |
ISO |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
increases activity |
EXP |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
|
increases activity |
ISO |
13 |
87,104,241 |
87,108,563 |
RGD:6480464 |
CTD |
| G |
Optn |
optineurin |
|
multiple interactions |
ISO |
17 |
84,298,122 |
84,348,330 |
RGD:6480464 |
CTD |
| G |
Pcsk9 |
proprotein convertase subtilisin/kexin type 9 |
|
multiple interactions |
ISO |
5 |
127,501,476 |
127,524,289 |
RGD:6480464 |
CTD |
| G |
Pon1 |
paraoxonase 1 |
|
multiple interactions |
EXP |
4 |
29,936,314 |
29,964,821 |
RGD:6480464 |
CTD |
| G |
Pon1 |
paraoxonase 1 |
|
decreases activity |
EXP |
4 |
29,936,314 |
29,964,821 |
RGD:6480464 |
CTD |
| G |
Ppara |
peroxisome proliferator activated receptor alpha |
|
multiple interactions |
ISO |
7 |
123,729,774 |
123,807,090 |
RGD:6480464 |
CTD |
| G |
Ppp1r12a |
protein phosphatase 1, regulatory subunit 12A |
|
multiple interactions |
EXP |
7 |
46,876,552 |
46,986,022 |
RGD:6480464 |
CTD |
| G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
|
multiple interactions |
ISO |
1 |
95,994,023 |
95,997,080 |
RGD:6480464 |
CTD |
| G |
Prdx3 |
peroxiredoxin 3 |
|
multiple interactions |
ISO |
1 |
267,468,371 |
267,481,273 |
RGD:6480464 |
CTD |
| G |
Procr |
protein C receptor, endothelial |
|
increases expression |
ISO |
3 |
146,268,567 |
146,273,718 |
RGD:6480464 |
CTD |
| G |
Rab27b |
RAB27B, member RAS oncogene family |
|
multiple interactions |
ISO |
18 |
66,682,627 |
66,747,813 |
RGD:6480464 |
CTD |
| G |
Rab32 |
RAB32, member RAS oncogene family |
|
multiple interactions |
ISO |
1 |
5,203,908 |
5,218,416 |
RGD:6480464 |
CTD |
| G |
Rab5b |
RAB5B, member RAS oncogene family |
|
multiple interactions |
ISO |
7 |
1,979,776 |
1,998,540 |
RGD:6480464 |
CTD |
| G |
Rabgap1l |
RAB GTPase activating protein 1-like |
|
multiple interactions |
ISO |
13 |
75,685,603 |
76,275,726 |
RGD:6480464 |
CTD |
| G |
Rap1a |
RAP1A, member of RAS oncogene family |
|
decreases prenylation |
ISO |
2 |
200,980,324 |
201,001,561 |
RGD:6480464 |
CTD |
| G |
Rb1 |
retinoblastoma 1 |
|
decreases phosphorylation |
ISO |
15 |
53,828,881 |
53,962,099 |
RGD:6480464 |
CTD |
| G |
Rgs11 |
regulator of G-protein signaling 11 |
|
multiple interactions |
ISO |
10 |
15,469,922 |
15,478,157 |
RGD:6480464 |
CTD |
| G |
Rhoa |
ras homolog family member A |
|
multiple interactions |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Rhoa |
ras homolog family member A |
|
multiple interactions |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Rhob |
ras homolog family member B |
|
multiple interactions |
ISO |
6 |
32,052,333 |
32,054,507 |
RGD:6480464 |
CTD |
| G |
Rims2 |
regulating synaptic membrane exocytosis 2 |
|
multiple interactions |
ISO |
7 |
74,757,003 |
75,271,771 |
RGD:6480464 |
CTD |
| G |
Rin2 |
Ras and Rab interactor 2 |
|
multiple interactions |
ISO |
3 |
134,307,538 |
134,503,915 |
RGD:6480464 |
CTD |
| G |
Rxra |
retinoid X receptor alpha |
|
multiple interactions |
ISO |
3 |
6,605,782 |
6,689,224 |
RGD:6480464 |
CTD |
| G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
|
affects expression |
EXP |
1 |
23,501,257 |
23,506,651 |
RGD:6480464 |
CTD |
| G |
Slc15a1 |
solute carrier family 15 (oligopeptide transporter), member 1 |
|
decreases activity |
ISO |
15 |
106,549,586 |
106,592,594 |
RGD:6480464 |
CTD |
| G |
Slco1b3 |
solute carrier organic anion transporter family, member 1b3 |
|
affects import |
ISO |
4 |
179,045,586 |
179,118,680 |
RGD:6480464 |
CTD |
| G |
Slco2b1 |
solute carrier organic anion transporter family, member 2b1 |
|
affects import |
ISO |
1 |
156,992,492 |
157,028,887 |
RGD:6480464 |
CTD |
| G |
Sod2 |
superoxide dismutase 2, mitochondrial |
|
multiple interactions |
ISO |
1 |
41,862,997 |
41,870,327 |
RGD:6480464 |
CTD |
| G |
Sos2 |
son of sevenless homolog 2 (Drosophila) |
|
multiple interactions |
ISO |
6 |
91,609,463 |
91,722,481 |
RGD:6480464 |
CTD |
| G |
Spin2a |
spindlin family, member 2A |
|
multiple interactions |
ISO |
X |
37,609,279 |
37,610,330 |
RGD:6480464 |
CTD |
| G |
Spp1 |
secreted phosphoprotein 1 |
|
multiple interactions |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Tfpi |
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
|
increases expression |
ISO |
3 |
67,654,389 |
67,697,178 |
RGD:6480464 |
CTD |
| G |
Tgfb1 |
transforming growth factor, beta 1 |
|
affects expression |
EXP |
1 |
80,894,705 |
80,911,020 |
RGD:6480464 |
CTD |
| G |
Tp53inp1 |
tumor protein p53 inducible nuclear protein 1 |
|
multiple interactions |
ISO |
5 |
25,008,253 |
25,014,263 |
RGD:6480464 |
CTD |
| G |
Vim |
vimentin |
|
multiple interactions |
EXP |
17 |
87,847,280 |
87,855,763 |
RGD:6480464 |
CTD |
| G |
Wnt11 |
wingless-type MMTV integration site family, member 11 |
|
multiple interactions |
ISO |
1 |
156,125,969 |
156,142,065 |
RGD:6480464 |
CTD |
Term paths to the root
|