Gene: Il2rg (interleukin 2 receptor subunit gamma) Rattus norvegicus
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Symbol: Il2rg
Name: interleukin 2 receptor subunit gamma
Description: ENCODES a protein that exhibits interleukin-2 binding (ortholog); INVOLVED IN positive regulation of B cell differentiation (ortholog); positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation (ortholog); positive regulation of gene expression (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-2 signaling pathway; interleukin-4 signaling pathway; ASSOCIATED WITH decreased leukocyte cell number; spleen hypoplasia; thymus hypoplasia; ASSOCIATED WITH combined T cell and B cell immunodeficiency; X-Linked Combined Immunodeficiency Diseases; Liver Cirrhosis, Experimental (ortholog); FOUND IN external side of plasma membrane (ortholog); membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ab2-183; Cd132; cytokine receptor common subunit gamma; interleukin 2 receptor, gamma (severe combined immunodeficiency); interleukin 2 receptor, gamma chain
Orthologs:
Homo sapiens (human) : IL2RG (interleukin 2 receptor subunit gamma)  HGNC  AGR
Mus musculus (house mouse) : Il2rg (interleukin 2 receptor, gamma chain)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Il2rg (interleukin 2 receptor subunit gamma)
Pan paniscus (bonobo/pygmy chimpanzee) : IL2RG (interleukin 2 receptor subunit gamma)
Canis lupus familiaris (dog) : IL2RG (interleukin 2 receptor subunit gamma)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il2rg (interleukin 2 receptor subunit gamma)
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Allele / Splice: Il2rgem2Mcwi   Il2rgem1Mcwi   Il2rgem3Mcwi   Il2rgem1Kyo   Il2rgem2Kyo   Il2rgem1Hina   Il2rgem6Kyo  
Genetic Models: F344-Il2rgem2Kyo F344-Il2rgem1Kyo W-Il2rgem1Hina F344-Prkdcem2KyoIl2rgem6Kyo SD-Rag2em3McwiIl2rgem2Mcwi SS-Il2rgem1Mcwi SD-Il2rgem3Mcwi SD-Il2rgem2Mcwi
Is Marker For: Strains:   F344-Prkdcem2KyoIl2rgem6Kyo   TM-Prkdcem4KyoIl2rgem5Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X71,165,378 - 71,169,078 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X72,017,856 - 72,021,516 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X89,342,055 - 89,345,715 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X89,416,495 - 89,419,068 (-)NCBI
CeleraX66,751,239 - 66,754,899 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Il2rg
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621466
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE