fumonisin - Ontology Report - Rat Genome Database

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

CHEBI ONTOLOGY - ANNOTATIONS

{{ watchLinkText }}

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	fumonisin	go back to main search page
Accession:	CHEBI:38224	browse the term
Definition:	A family of toxins produced by several species of Fusarium moulds which occur mainly in maize.
Synonyms:	related_synonym:	fumonisins

show annotations for term's descendants Sort by:
Rat (371) Mouse (407) Human (375) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (48) Green Monkey (0) Naked Mole-rat (0) All
Genes (407)

fumonisin B1

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

decreases expression

fumonisin B1 results in decreased expression of PZP mRNA

NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186

G

aminoadipate-semialdehyde synthase

decreases expression

fumonisin B1 results in decreased expression of AASS mRNA

NCBI chr 6:23,072,172...23,132,985
Ensembl chr 6:23,072,172...23,132,985

G

ATP-binding cassette, sub-family B member 1A

multiple interactions

fumonisin B1 inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein]
fumonisin B1 inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]

PMID:24448832 PMID:34915026

NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575

G

ATP-binding cassette, sub-family B member 4

increases expression

fumonisin B1 results in increased expression of ABCB4 mRNA

NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231

G

ATP binding cassette subfamily G member 8

multiple interactions

[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of ABCG8 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of ABCG8 mRNA

NCBI chr17:84,983,730...85,007,761
Ensembl chr17:84,983,730...85,007,761

G

atypical chemokine receptor 3

decreases expression

fumonisin B1 results in decreased expression of ACKR3 mRNA

NCBI chr 1:90,131,702...90,143,446
Ensembl chr 1:90,131,702...90,144,473

G

acyl-CoA thioesterase 2

increases expression

fumonisin B1 results in increased expression of ACOT2 mRNA

NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647

G

acyl-CoA synthetase long-chain family member 1

decreases expression

fumonisin B1 results in decreased expression of ACSL1 mRNA

NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088

G

actin, gamma, cytoplasmic 1

increases expression

fumonisin B1 results in increased expression of ACTG1 mRNA

NCBI chr11:120,236,513...120,239,321
Ensembl chr11:120,236,516...120,239,368

G

actin related protein 2

increases expression

fumonisin B1 results in increased expression of ACTR2 mRNA

NCBI chr11:20,012,304...20,062,951
Ensembl chr11:20,012,304...20,062,913

G

afamin

decreases expression

fumonisin B1 results in decreased expression of AFM mRNA

NCBI chr 5:90,666,808...90,701,403
Ensembl chr 5:90,666,791...90,701,402

G

angiotensinogen

multiple interactions
decreases expression

fumonisin B1 inhibits the reaction [AGT protein results in increased expression of MDM2 mRNA]; fumonisin B1 inhibits the reaction [AGT protein results in increased expression of MDM2 protein]
fumonisin B1 results in decreased expression of AGT mRNA

PMID:16221962 PMID:18206046

NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445

G

alanine-glyoxylate aminotransferase

decreases expression

fumonisin B1 results in decreased expression of AGXT mRNA

NCBI chr 1:93,062,962...93,073,143
Ensembl chr 1:93,062,962...93,073,143

G

S-adenosylhomocysteine hydrolase

decreases expression

fumonisin B1 results in decreased expression of AHCY mRNA

NCBI chr 2:154,901,230...154,916,417
Ensembl chr 2:154,901,230...154,916,417

G

aryl-hydrocarbon receptor

increases activity

fumonisin B1 results in increased activity of AHR protein

NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037

G

alpha-2-HS-glycoprotein

increases expression

fumonisin B1 results in increased expression of AHSG mRNA

NCBI chr16:22,710,793...22,718,193
Ensembl chr16:22,710,027...22,718,199

G

aldo-keto reductase family 1, member A1

increases expression

fumonisin B1 results in increased expression of AKR1A1 mRNA

NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877

G

aldo-keto reductase family 1, member B7

increases expression

fumonisin B1 results in increased expression of AKR1B7 mRNA

NCBI chr 6:34,389,297...34,400,072
Ensembl chr 6:34,389,269...34,400,077

G

activated leukocyte cell adhesion molecule

increases expression

fumonisin B1 results in increased expression of ALCAM mRNA

NCBI chr16:52,069,359...52,273,444
Ensembl chr16:52,069,359...52,274,437

G

aldehyde dehydrogenase family 1, subfamily A1

increases expression

fumonisin B1 results in increased expression of ALDH1A1 mRNA

NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829

G

aldehyde dehydrogenase family 1, subfamily A7

increases expression

fumonisin B1 results in increased expression of ALDH1A7 mRNA

NCBI chr19:20,670,318...20,704,920
Ensembl chr19:20,670,317...20,704,926

G

aldehyde dehydrogenase family 3, subfamily A2

increases expression

fumonisin B1 results in increased expression of ALDH3A2 mRNA

NCBI chr11:61,114,240...61,158,267
Ensembl chr11:61,114,243...61,158,290

G

aldolase B, fructose-bisphosphate

decreases expression

fumonisin B1 results in decreased expression of ALDOB mRNA

NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546

G

aldolase C, fructose-bisphosphate

increases expression

fumonisin B1 results in increased expression of ALDOA mRNA

NCBI chr11:78,213,899...78,218,607
Ensembl chr11:78,213,794...78,218,607

G

alkB homolog 5, RNA demethylase

decreases expression

fumonisin B1 results in decreased expression of ALKBH5 mRNA

NCBI chr11:60,428,509...60,449,338
Ensembl chr11:60,427,207...60,449,338

G

annexin A2

increases expression

fumonisin B1 results in increased expression of ANXA2 mRNA

NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077

G

annexin A5

increases expression

fumonisin B1 results in increased expression of ANXA5 mRNA

NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043

G

apoptotic peptidase activating factor 1

multiple interactions

[fumonisin B1 co-treated with ochratoxin A] results in increased expression of APAF1 protein; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of APAF1 mRNA]

NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632

G

amyloid P component, serum

decreases expression

fumonisin B1 results in decreased expression of APCS mRNA

NCBI chr 1:172,721,528...172,722,516
Ensembl chr 1:172,721,528...172,722,608

G

apolipoprotein A-IV

increases expression

fumonisin B1 results in increased expression of APOA4 mRNA

NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757

G

apolipoprotein C-IV

decreases expression

fumonisin B1 results in decreased expression of APOC4 mRNA

NCBI chr 7:19,412,009...19,415,385
Ensembl chr 7:19,412,008...19,415,404

G

amyloid beta precursor protein

increases expression

fumonisin B1 results in increased expression of APP mRNA

NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654

G

Rho GDP dissociation inhibitor alpha

increases expression

fumonisin B1 results in increased expression of ARHGDIA mRNA

NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450

G

argininosuccinate lyase

decreases expression

fumonisin B1 results in decreased expression of ASL mRNA

NCBI chr 5:130,040,099...130,053,222
Ensembl chr 5:130,040,099...130,058,088

G

activating transcription factor 4

increases expression
multiple interactions

fumonisin B1 results in increased expression of ATF4 mRNA; fumonisin B1 results in increased expression of ATF4 protein
EIF2AK3 protein affects the reaction [fumonisin B1 results in increased expression of ATF4 protein]

NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742

G

antioxidant 1 copper chaperone

increases expression

fumonisin B1 results in increased expression of ATOX1 mRNA

NCBI chr11:55,337,463...55,352,034
Ensembl chr11:55,337,467...55,352,065

G

ATPase, H+ transporting, lysosomal V0 subunit C

increases expression

fumonisin B1 results in increased expression of ATP6V0C mRNA

NCBI chr17:24,382,839...24,388,652
Ensembl chr17:24,382,840...24,388,676

G

ATPase, H+ transporting, lysosomal V0 subunit E

increases expression

fumonisin B1 results in increased expression of ATP6V0E mRNA

NCBI chr17:26,895,370...26,918,621
Ensembl chr17:26,882,205...26,918,621

G

ataxin 10

increases expression

fumonisin B1 results in increased expression of ATXN10 mRNA

NCBI chr15:85,220,456...85,348,038
Ensembl chr15:85,220,446...85,347,413

G

BCL2-associated X protein

multiple interactions
increases expression
affects expression

[fumonisin B1 results in decreased chemical synthesis of Ceramides] which results in decreased expression of BAX protein
fumonisin B1 results in increased expression of BAX mRNA; fumonisin B1 results in increased expression of BAX protein
fumonisin B1 affects the expression of BAX mRNA
[fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX protein; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of BAX mRNA]

PMID:25195822 PMID:31891755 PMID:35697133 PMID:36397609

NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322

G

B cell leukemia/lymphoma 2

decreases expression
multiple interactions

fumonisin B1 results in decreased expression of BCL2 mRNA; fumonisin B1 results in decreased expression of BCL2 protein
fumonisin B1 promotes the reaction [ochratoxin A results in decreased expression of BCL2 mRNA]; fumonisin B1 promotes the reaction [ochratoxin A results in decreased expression of BCL2 protein]

PMID:31891755 PMID:36397609

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

G

betaine-homocysteine methyltransferase

decreases expression

fumonisin B1 results in decreased expression of BHMT mRNA

NCBI chr13:93,753,399...93,774,266
Ensembl chr13:93,753,183...93,774,469

G

complement component 1, q subcomponent, alpha polypeptide

increases expression

fumonisin B1 results in increased expression of C1QA mRNA

NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114

G

complement component 1, q subcomponent, beta polypeptide

increases expression

fumonisin B1 results in increased expression of C1QB mRNA

NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498

G

complement component 4 binding protein

increases expression

fumonisin B1 results in increased expression of C4BP mRNA

NCBI chr 1:130,562,510...130,589,365
Ensembl chr 1:130,562,510...130,589,369

G

calmodulin 2

increases expression

fumonisin B1 results in increased expression of CALM2 mRNA

NCBI chr17:87,740,829...87,754,363
Ensembl chr17:87,740,840...87,754,363

G

calpain 2

increases expression

fumonisin B1 results in increased expression of CAPN2 mRNA

NCBI chr 1:182,294,818...182,345,175
Ensembl chr 1:182,294,825...182,345,173

G

calpain, small subunit 1

increases expression

fumonisin B1 results in increased expression of CAPNS1 mRNA

NCBI chr 7:29,886,359...29,898,308
Ensembl chr 7:29,886,361...29,898,236

G

carbonic anhydrase 3

decreases expression

fumonisin B1 results in decreased expression of CAR3 mRNA

NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583

G

carbonic anhydrase 5a, mitochondrial

decreases expression

fumonisin B1 results in decreased expression of CAR5A mRNA

NCBI chr 8:122,642,874...122,671,651
Ensembl chr 8:122,642,865...122,671,643

G

caspase 1

increases cleavage
multiple interactions
increases expression

fumonisin B1 results in increased cleavage of CASP1 protein
deoxynivalenol promotes the reaction [fumonisin B1 results in increased cleavage of CASP1 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased cleavage of CASP1 protein]
fumonisin B1 results in increased expression of CASP1 mRNA

NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290

G

caspase 3

multiple interactions
increases expression
decreases expression

fumonisin B1 results in decreased expression of and results in increased cleavage of CASP3 protein
fumonisin B1 results in increased expression of CASP3 mRNA
fumonisin B1 results in decreased expression of CASP3 mRNA
[fumonisin B1 co-treated with ochratoxin A] results in increased cleavage of CASP3 protein; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP3 mRNA]

PMID:31891755 PMID:35697133 PMID:36397609

NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724

G

caspase 7

multiple interactions

[fumonisin B1 results in decreased chemical synthesis of Ceramides] which results in decreased expression of CASP7 protein modified form

NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776

G

caspase 9

multiple interactions

[fumonisin B1 co-treated with ochratoxin A] results in increased cleavage of CASP9 protein; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CASP9 mRNA]

NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287

G

catalase

increases activity
decreases expression
multiple interactions

fumonisin B1 results in increased activity of CAT protein
fumonisin B1 results in decreased expression of CAT mRNA
[Aflatoxin B1 co-treated with fumonisin B1] results in increased activity of CAT protein

PMID:20015463 PMID:28181396 PMID:35697133

NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505

G

C-C motif chemokine ligand 20

increases expression

fumonisin B1 results in increased expression of CCL20 mRNA

NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888

G

C-C motif chemokine ligand 4

increases expression

fumonisin B1 results in increased expression of CCL4 mRNA

NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509

G

C-C motif chemokine ligand 5

increases expression

fumonisin B1 results in increased expression of CCL5 mRNA

NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344

G

cyclin D1

increases expression

fumonisin B1 results in increased expression of CCND1 mRNA

NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662

G

C-C motif chemokine receptor 1

increases expression

fumonisin B1 results in increased expression of CCR1 mRNA

NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729

G

C-C motif chemokine receptor 4

increases expression

fumonisin B1 results in increased expression of CCR4 mRNA

NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984

G

CD164 antigen

increases expression

fumonisin B1 results in increased expression of CD164 mRNA

NCBI chr10:41,395,496...41,407,038
Ensembl chr10:41,395,410...41,407,044

G

CD5 antigen-like

increases expression

fumonisin B1 results in increased expression of CD5L mRNA

NCBI chr 3:87,265,188...87,278,381
Ensembl chr 3:87,265,188...87,278,380

G

CD63 antigen

increases expression
multiple interactions

fumonisin B1 results in increased expression of CD63 mRNA
[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of CD63 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of CD63 mRNA

PMID:16221962 PMID:30448865

NCBI chr10:128,731,577...128,748,691
Ensembl chr10:128,736,858...128,748,691

G

CD81 antigen

increases expression

fumonisin B1 results in increased expression of CD81 mRNA

NCBI chr 7:142,606,487...142,621,667
Ensembl chr 7:142,606,476...142,621,671

G

CD9 antigen

increases expression

fumonisin B1 results in increased expression of CD9 mRNA

NCBI chr 6:125,437,229...125,471,723
Ensembl chr 6:125,437,229...125,471,754

G

cell division cycle 42

increases expression

fumonisin B1 results in increased expression of CDC42 mRNA

NCBI chr 4:137,047,011...137,085,007
Ensembl chr 4:137,047,007...137,085,031

G

cyclin dependent kinase inhibitor 1A

increases expression
multiple interactions

fumonisin B1 results in increased expression of CDKN1A mRNA
[fumonisin B1 results in decreased chemical synthesis of Ceramides] which results in decreased expression of CDKN1A protein

PMID:16221962 PMID:25195822

NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701

G

cyclin dependent kinase inhibitor 2A

increases expression

fumonisin B1 results in increased expression of CDKN2A mRNA

NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890

G

cyclin dependent kinase inhibitor 2B

increases expression

fumonisin B1 results in increased expression of CDKN2B mRNA

NCBI chr 4:89,224,526...89,229,269
Ensembl chr 4:89,224,536...89,229,276

G

carnitine deficiency-associated gene expressed in ventricle 3

increases expression

fumonisin B1 results in increased expression of CDV3 mRNA

NCBI chr 9:103,230,301...103,243,034
Ensembl chr 9:103,230,293...103,243,039

G

CEA cell adhesion molecule 1

decreases expression

fumonisin B1 results in decreased expression of CEACAM1 mRNA

NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028

G

ceramide synthase 2

multiple interactions

[fumonisin B1 co-treated with Particulate Matter] results in increased expression of CERS2 mRNA; [fumonisin B1 co-treated with Vehicle Emissions] results in increased expression of CERS2 mRNA

NCBI chr 3:95,222,077...95,230,910
Ensembl chr 3:95,222,102...95,230,910

G

carboxylesterase 1C

decreases expression

fumonisin B1 results in decreased expression of CES1C mRNA

NCBI chr 8:93,825,643...93,857,911
Ensembl chr 8:93,825,643...93,857,911

G

carboxylesterase 1D

increases expression

fumonisin B1 results in increased expression of CES1 mRNA

NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466

G

carboxylesterase 3A

decreases expression

fumonisin B1 results in decreased expression of CES3A mRNA

NCBI chr 8:105,775,208...105,788,560
Ensembl chr 8:105,775,233...105,785,045

G

carboxylesterase 3B

decreases expression

fumonisin B1 results in decreased expression of CES3 mRNA

NCBI chr 8:105,810,365...105,820,561
Ensembl chr 8:105,810,385...105,820,561

G

complement component factor h

decreases expression

fumonisin B1 results in decreased expression of CFH mRNA

NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502

G

cofilin 1, non-muscle

increases expression

fumonisin B1 results in increased expression of CFL1 mRNA

NCBI chr19:5,540,483...5,544,059
Ensembl chr19:5,540,483...5,545,229

G

complement factor properdin

increases expression

fumonisin B1 results in increased expression of CFP mRNA

NCBI chr X:20,791,693...20,797,794
Ensembl chr X:20,791,693...20,797,794

G

claudin 3

decreases expression
multiple interactions

fumonisin B1 results in decreased expression of CLDN3 mRNA
illite inhibits the reaction [fumonisin B1 results in decreased expression of CLDN3 mRNA]

NCBI chr 5:135,015,068...135,016,330
Ensembl chr 5:135,015,068...135,016,326

G

claudin 4

decreases expression
multiple interactions

fumonisin B1 results in decreased expression of CLDN4 mRNA
illite inhibits the reaction [fumonisin B1 results in decreased expression of CLDN4 mRNA]

NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788

G

C-type lectin domain family 4, member f

increases expression

fumonisin B1 results in increased expression of CLEC4F mRNA

NCBI chr 6:83,621,524...83,633,098
Ensembl chr 6:83,621,524...83,633,169

G

clathrin heavy chain

increases expression

fumonisin B1 results in increased expression of CLTC mRNA

NCBI chr11:86,585,178...86,648,637
Ensembl chr11:86,585,177...86,648,391

G

clusterin

increases expression

fumonisin B1 results in increased expression of CLU mRNA

NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996

G

collagen, type XVIII, alpha 1

decreases expression

fumonisin B1 results in decreased expression of COL18A1 mRNA

NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382

G

collagen, type I, alpha 1

multiple interactions

[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of COL1A1 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of COL1A1 mRNA

NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868

G

collagen, type III, alpha 1

multiple interactions

[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of COL3A1 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of COL3A1 mRNA

NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866

G

cytochrome c oxidase subunit 7B

decreases expression

fumonisin B1 results in decreased expression of COX7B mRNA

NCBI chr X:105,059,306...105,066,056
Ensembl chr X:105,059,306...105,066,056

G

ceruloplasmin

increases expression

fumonisin B1 results in increased expression of CP mRNA

NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309

G

C-reactive protein, pentraxin-related

decreases expression

fumonisin B1 results in decreased expression of CRP mRNA

NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598

G

cystatin B

increases expression

fumonisin B1 results in increased expression of CSTB mRNA

NCBI chr10:78,261,504...78,263,456
Ensembl chr10:78,261,503...78,263,456

G

cytotoxic T-lymphocyte-associated protein 4

increases expression

fumonisin B1 results in increased expression of CTLA4 mRNA

NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991

G

catenin alpha 1

increases expression

fumonisin B1 results in increased expression of CTNNA1 mRNA

NCBI chr18:35,251,955...35,387,829
Ensembl chr18:35,251,912...35,387,832

G

catenin beta 1

increases expression

fumonisin B1 results in increased expression of CTNNB1 mRNA

NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573

G

cathepsin B

increases expression

fumonisin B1 results in increased expression of CTSB mRNA

NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372

G

cathepsin D

increases expression

fumonisin B1 results in increased expression of CTSD mRNA

NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775

G

cathepsin L

increases expression

fumonisin B1 results in increased expression of CTSL mRNA

NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704

G

cathepsin S

increases expression

fumonisin B1 results in increased expression of CTSS mRNA

NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714

G

C-X-C motif chemokine ligand 1

decreases expression

fumonisin B1 results in decreased expression of CXCL1 mRNA

NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974

G

chemokine (C-X-C motif) ligand 11

increases expression

fumonisin B1 results in increased expression of CXCL11 mRNA

NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344

G

C-X-C motif chemokine ligand 12

decreases expression

fumonisin B1 results in decreased expression of CXCL12 mRNA

NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328

G

C-X-C motif chemokine ligand 14

multiple interactions

[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of CXCL14 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of CXCL14 mRNA

NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364

G

C-X-C motif chemokine ligand 15

increases expression

fumonisin B1 results in increased expression of CXCL8 mRNA

NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926

G

C-X-C motif chemokine ligand 2

increases expression

fumonisin B1 results in increased expression of CXCL2 mRNA

NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797

G

C-X-C motif chemokine ligand 3

decreases expression

fumonisin B1 results in decreased expression of CXCL1 mRNA

NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459

G

C-X-C motif chemokine receptor 4

decreases expression

fumonisin B1 results in decreased expression of CXCR4 mRNA

NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030

G

C-X-C motif chemokine receptor 5

decreases expression

fumonisin B1 results in decreased expression of CXCR5 mRNA

NCBI chr 9:44,423,084...44,437,741
Ensembl chr 9:44,423,084...44,473,174

G

cytochrome b5 type B

decreases expression

fumonisin B1 results in decreased expression of CYB5B mRNA

NCBI chr 8:107,877,293...107,914,102
Ensembl chr 8:107,877,272...107,914,103

G

cytochrome c, somatic

increases expression
multiple interactions

fumonisin B1 results in increased expression of CYCS mRNA; fumonisin B1 results in increased expression of CYCS protein
fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of CYCS mRNA]

PMID:31891755 PMID:36397609

NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518

G

cytochrome P450, family 17, subfamily a, polypeptide 1

decreases expression

fumonisin B1 results in decreased expression of CYP17A1 mRNA

NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
increases activity

fumonisin B1 results in increased expression of CYP1A1 mRNA
fumonisin B1 results in increased activity of CYP1A1 protein

NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression

fumonisin B1 results in increased expression of CYP1B1 mRNA; fumonisin B1 results in increased expression of CYP1B1 protein

NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490

G

cytochrome P450, family 2, subfamily a, polypeptide 4

increases expression

fumonisin B1 results in increased expression of CYP2A4 mRNA

NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513

G

cytochrome P450, family 2, subfamily c, polypeptide 29

decreases expression

fumonisin B1 results in decreased expression of CYP2C29 mRNA

NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157

G

cytochrome P450, family 2. subfamily c, polypeptide 37

decreases expression

fumonisin B1 results in decreased expression of CYP2C37 mRNA

NCBI chr19:39,980,868...40,000,687
Ensembl chr19:39,980,868...40,000,687

G

cytochrome P450, family 2, subfamily c, polypeptide 40

decreases expression

fumonisin B1 results in decreased expression of CYP2C40 mRNA

NCBI chr19:39,755,517...39,801,258
Ensembl chr19:39,755,515...39,801,258

G

cytochrome P450, family 2, subfamily c, polypeptide 70

decreases expression

fumonisin B1 results in decreased expression of CYP2C70 mRNA

NCBI chr19:40,141,805...40,175,730
Ensembl chr19:40,141,797...40,175,777

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases expression

fumonisin B1 results in decreased expression of CYP2E1 mRNA

NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900

G

cytochrome P450, family 3, subfamily a, polypeptide 11

increases expression

fumonisin B1 results in increased expression of CYP3A11 mRNA

NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774

G

cytochrome P450, family 3, subfamily a, polypeptide 13

decreases expression

fumonisin B1 results in decreased expression of CYP3A13 mRNA

NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881

G

cytochrome P450, family 3, subfamily a, polypeptide 16

increases expression

fumonisin B1 results in increased expression of CYP3A16 mRNA

NCBI chr 5:145,373,119...145,406,550
Ensembl chr 5:145,373,119...145,406,533

G

cytochrome P450, family 3, subfamily a, polypeptide 25

decreases expression

fumonisin B1 results in decreased expression of CYP3A25 mRNA

NCBI chr 5:145,914,002...145,946,454
Ensembl chr 5:145,914,004...145,946,428

G

cytochrome P450, family 4, subfamily a, polypeptide 10

decreases expression

fumonisin B1 results in decreased expression of CYP4A10 mRNA

NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846

G

cytochrome P450, family 4, subfamily a, polypeptide 14

decreases expression

fumonisin B1 results in decreased expression of CYP4A14 mRNA

NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339

G

cytochrome P450, family 7, subfamily b, polypeptide 1

multiple interactions

[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of CYP7B1 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of CYP7B1 mRNA

NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502

G

cytochrome P450, family 8, subfamily b, polypeptide 1

decreases expression

fumonisin B1 results in decreased expression of CYP8B1 mRNA

NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371

G

damage specific DNA binding protein 1

increases expression

fumonisin B1 results in increased expression of DDB1 mRNA

NCBI chr19:10,582,961...10,607,186
Ensembl chr19:10,582,691...10,607,183

G

DNA-damage inducible transcript 3

increases expression
multiple interactions

fumonisin B1 results in increased expression of DDIT3 mRNA; fumonisin B1 results in increased expression of DDIT3 protein
4-phenylbutyric acid inhibits the reaction [fumonisin B1 results in increased expression of DDIT3 protein]; EIF2AK3 protein affects the reaction [fumonisin B1 results in increased expression of DDIT3 protein]; thermozymocidin inhibits the reaction [fumonisin B1 results in increased expression of DDIT3 protein]

NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157

G

D-dopachrome tautomerase

decreases expression

fumonisin B1 results in decreased expression of DDT mRNA

NCBI chr10:75,607,067...75,609,208
Ensembl chr10:75,607,064...75,609,248

G

DEAD box helicase 1

increases expression

fumonisin B1 results in increased expression of DDX1 mRNA

NCBI chr12:13,269,308...13,299,175
Ensembl chr12:13,266,974...13,299,214

G

delta 4-desaturase, sphingolipid 1

increases expression

fumonisin B1 results in increased expression of DEGS1 mRNA

NCBI chr 1:182,103,529...182,110,366
Ensembl chr 1:182,103,337...182,110,369

G

diablo, IAP-binding mitochondrial protein

decreases expression

fumonisin B1 results in decreased expression of DIABLO protein

NCBI chr 5:123,649,393...123,664,825
Ensembl chr 5:123,647,828...123,662,239

G

deiodinase, iodothyronine, type I

decreases expression

fumonisin B1 results in decreased expression of DIO1 mRNA

NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366

G

deleted in malignant brain tumors 1

decreases expression

fumonisin B1 results in decreased expression of DMBT1 mRNA

NCBI chr 7:130,633,787...130,723,357
Ensembl chr 7:130,633,776...130,723,357

G

dystrophia myotonica-protein kinase

increases expression

fumonisin B1 results in increased expression of DMPK mRNA

NCBI chr 7:18,817,571...18,827,746
Ensembl chr 7:18,817,774...18,827,746

G

DNA methyltransferase 1

decreases activity

fumonisin B1 results in decreased activity of DNMT1 protein

NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184

G

DNA methyltransferase 3A

decreases activity

fumonisin B1 results in decreased activity of DNMT3A protein

NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443

G

DNA methyltransferase 3B

decreases activity

fumonisin B1 results in decreased activity of DNMT3B protein

NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650

G

dual specificity phosphatase 16

increases expression

fumonisin B1 results in increased expression of DUSP16 mRNA

NCBI chr 6:134,692,431...134,769,687
Ensembl chr 6:134,692,431...134,769,588

G

EBP cholestenol delta-isomerase

decreases expression

fumonisin B1 results in decreased expression of EBP mRNA

NCBI chr X:8,051,568...8,059,751
Ensembl chr X:8,051,568...8,059,751

G

enoyl Coenzyme A hydratase, short chain, 1, mitochondrial

decreases expression

fumonisin B1 results in decreased expression of ECHS1 mRNA

NCBI chr 7:139,685,623...139,696,334
Ensembl chr 7:139,685,623...139,696,389

G

eukaryotic translation initiation factor 2 alpha kinase 3

increases expression
multiple interactions

fumonisin B1 results in increased expression of EIF2AK3 protein
EIF2AK3 protein affects the reaction [fumonisin B1 results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [fumonisin B1 results in increased expression of DDIT3 protein]

NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229

G

eukaryotic translation initiation factor 6

increases expression

fumonisin B1 results in increased expression of EIF6 mRNA

NCBI chr 2:155,661,757...155,668,845
Ensembl chr 2:155,661,752...155,668,845

G

ELOVL fatty acid elongase 7

multiple interactions

[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of ELOVL7 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of ELOVL7 mRNA

NCBI chr13:108,350,860...108,423,643
Ensembl chr13:108,350,938...108,422,217

G

glutamyl aminopeptidase

decreases expression

fumonisin B1 results in decreased expression of ENPEP mRNA

NCBI chr 3:129,062,826...129,126,398
Ensembl chr 3:129,062,824...129,126,369

G

ectonucleoside triphosphate diphosphohydrolase 5

increases expression

fumonisin B1 results in increased expression of ENTPD5 mRNA

NCBI chr12:84,420,649...84,455,803
Ensembl chr12:84,420,631...84,455,803

G

epoxide hydrolase 1, microsomal

increases expression

fumonisin B1 results in increased expression of EPHX1 mRNA

NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469

G

esterase D/formylglutathione hydrolase

increases expression

fumonisin B1 results in increased expression of ESD mRNA

NCBI chr14:74,969,591...74,988,205
Ensembl chr14:74,969,737...74,988,205

G

coagulation factor X

decreases expression

fumonisin B1 results in decreased expression of F10 mRNA

NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676

G

F11 receptor

increases expression

fumonisin B1 results in increased expression of F11R mRNA

NCBI chr 1:171,265,129...171,292,161
Ensembl chr 1:171,265,103...171,292,171

G

coagulation factor VII

decreases expression

fumonisin B1 results in decreased expression of F7 mRNA

NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809

G

fatty acid binding protein 1, liver

decreases expression

fumonisin B1 results in decreased expression of FABP1 mRNA

NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007

G

fumarylacetoacetate hydrolase

decreases expression

fumonisin B1 results in decreased expression of FAH mRNA

NCBI chr 7:84,234,367...84,255,150
Ensembl chr 7:84,234,367...84,255,930

G

Fas cell surface death receptor

multiple interactions

fumonisin B1 inhibits the reaction [[sorafenib co-treated with vorinostat] affects the localization of and results in increased activity of FAS protein]

NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172

G

fructose bisphosphatase 1

decreases expression

fumonisin B1 results in decreased expression of FBP1 mRNA

NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096

G

farnesyl diphosphate farnesyl transferase 1

decreases expression

fumonisin B1 results in decreased expression of FDFT1 mRNA

NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027

G

farnesyl diphosphate synthetase

decreases expression

fumonisin B1 results in decreased expression of FDPS mRNA

NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266

G

FK506 binding protein 1a

increases expression

fumonisin B1 results in increased expression of FKBP1A mRNA

NCBI chr 2:151,384,403...151,403,611
Ensembl chr 2:151,384,403...151,403,612

G

flavin containing monooxygenase 3

decreases expression

fumonisin B1 results in decreased expression of FMO3 mRNA

NCBI chr 1:162,781,368...162,812,097
Ensembl chr 1:162,781,369...162,812,097

G

flavin containing monooxygenase 5

increases expression

fumonisin B1 results in increased expression of FMO5 mRNA

NCBI chr 3:97,517,248...97,562,603
Ensembl chr 3:97,536,120...97,562,598

G

forkhead box A2

decreases expression

fumonisin B1 results in decreased expression of FOXA2 mRNA

NCBI chr 2:147,884,797...147,888,889
Ensembl chr 2:147,884,797...147,888,889

G

forkhead box P3

decreases expression

fumonisin B1 results in decreased expression of FOXP3 mRNA

NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484

G

folylpolyglutamyl synthetase

decreases expression

fumonisin B1 results in decreased expression of FPGS mRNA

NCBI chr 2:32,572,621...32,594,163
Ensembl chr 2:32,572,621...32,594,157

G

ferritin light polypeptide 1

increases expression

fumonisin B1 results in increased expression of FTL1 mRNA

NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308

G

FTO alpha-ketoglutarate dependent dioxygenase

decreases expression

fumonisin B1 results in decreased expression of FTO mRNA

NCBI chr 8:92,039,995...92,395,061
Ensembl chr 8:92,040,153...92,395,067

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

fumonisin B1 results in decreased expression of G6PC1 mRNA

NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729

G

growth arrest and DNA-damage-inducible 45 alpha

increases expression

fumonisin B1 results in increased expression of GADD45A mRNA; fumonisin B1 results in increased expression of GADD45A protein

NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441

G

glycyl-tRNA synthetase 1

increases expression

fumonisin B1 results in increased expression of GARS1 mRNA

NCBI chr 6:55,014,986...55,056,489
Ensembl chr 6:55,014,992...55,056,485

G

glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)

decreases expression

fumonisin B1 results in decreased expression of GCAT mRNA

NCBI chr15:78,915,074...78,926,731
Ensembl chr15:78,915,074...78,922,553
Ensembl chr15:78,915,074...78,922,553

G

glutamate-cysteine ligase, modifier subunit

decreases expression

fumonisin B1 results in decreased expression of GCLM mRNA

NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381

G

growth hormone receptor

decreases expression

fumonisin B1 results in decreased expression of GHR mRNA

NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974

G

glutamate-ammonia ligase

decreases expression

fumonisin B1 results in decreased expression of GLUL mRNA

NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469

G

predicted gene 13754

decreases expression

fumonisin B1 results in decreased expression of CPO mRNA

NCBI chr 1:63,957,040...63,973,947
Ensembl chr 1:63,957,007...63,975,091

G

G protein subunit alpha i2

increases expression

fumonisin B1 results in increased expression of GNAI2 mRNA

NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566

G

GNAS complex locus

increases expression

fumonisin B1 results in increased expression of GNAS mRNA

NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537

G

guanine nucleotide binding protein (G protein), beta 1

increases expression

fumonisin B1 results in increased expression of GNB1 mRNA

NCBI chr 4:155,575,514...155,643,726
Ensembl chr 4:155,575,818...155,643,726

G

glycine N-methyltransferase

decreases expression

fumonisin B1 results in decreased expression of GNMT mRNA

NCBI chr17:47,036,590...47,040,091
Ensembl chr17:47,036,590...47,040,094

G

glycerol-3-phosphate acyltransferase, mitochondrial

decreases expression

fumonisin B1 results in decreased expression of GPAM mRNA

NCBI chr19:55,056,067...55,115,666
Ensembl chr19:55,055,700...55,115,670

G

glutamic pyruvic transaminase, soluble

increases activity
multiple interactions

fumonisin B1 results in increased activity of GPT protein
[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of GPT protein; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of GPT protein

PMID:17080400 PMID:30448865

NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886

G

glutamate receptor, ionotropic, NMDA1 (zeta 1)

decreases expression

fumonisin B1 results in decreased expression of GRIN1 mRNA

NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199

G

granulin

increases expression

fumonisin B1 results in increased expression of GRN mRNA

NCBI chr11:102,321,333...102,327,635
Ensembl chr11:102,321,141...102,327,874

G

gasdermin D

multiple interactions
increases expression

deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of GSDMD mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of GSDMD protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of GSDMD mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of GSDMD protein]
fumonisin B1 results in increased expression of GSDMD mRNA; fumonisin B1 results in increased expression of GSDMD protein

NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257

G

glutathione S-transferase, alpha 3

decreases expression
affects expression

fumonisin B1 results in decreased expression of GSTA3 mRNA
fumonisin B1 affects the expression of GSTA3 mRNA

PMID:16221962 PMID:35697133

NCBI chr 1:21,310,837...21,335,885
Ensembl chr 1:21,310,813...21,335,885

G

glutathione S-transferase alpha 5

increases expression

fumonisin B1 results in increased expression of GSTA2 mRNA

NCBI chr 9:78,197,210...78,212,807
Ensembl chr 9:78,197,205...78,212,807

G

glutathione S-transferase, mu 1

increases expression
decreases expression

fumonisin B1 results in increased expression of GSTM1 mRNA
fumonisin B1 results in decreased expression of GSTM1 mRNA

PMID:16221962 PMID:35697133

NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289

G

glutathione S-transferase, mu 2

increases expression

fumonisin B1 results in increased expression of GSTM2 mRNA

NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769

G

glutathione S-transferase, mu 5

increases expression

fumonisin B1 results in increased expression of GSTM3 mRNA

NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002

G

glutathione S-transferase, pi 1

affects expression

fumonisin B1 affects the expression of GSTP1 mRNA

NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985

G

glutathione S-transferase, pi 2

increases expression

fumonisin B1 results in increased expression of GSTP2 mRNA

NCBI chr19:4,090,288...4,092,221
Ensembl chr19:4,090,285...4,096,023

G

glutathione transferase zeta 1 (maleylacetoacetate isomerase)

decreases expression

fumonisin B1 results in decreased expression of GSTZ1 mRNA

NCBI chr12:87,192,102...87,211,497
Ensembl chr12:87,193,939...87,211,497

G

H1.2 linker histone, cluster member

increases expression

fumonisin B1 results in increased expression of H1F2 mRNA

NCBI chr13:23,922,790...23,923,514
Ensembl chr13:23,922,791...23,924,350

G

histocompatibility 2, D region locus 1

increases expression

fumonisin B1 results in increased expression of H2-D1 mRNA

NCBI chr17:35,482,070...35,486,473
Ensembl chr17:35,481,706...35,486,475

G

histocompatibility 2, Q region locus 1

increases expression

fumonisin B1 results in increased expression of H2-Q1 mRNA

NCBI chr17:35,539,503...35,547,118
Ensembl chr17:35,539,381...35,544,075

G

histocompatibility 2, T region locus 10

increases expression

fumonisin B1 results in increased expression of H2-T10 mRNA

NCBI chr17:36,426,763...36,432,336
Ensembl chr17:36,426,768...36,432,357

G

histocompatibility 2, T region locus 22

increases expression

fumonisin B1 results in increased expression of H2-T22 mRNA

NCBI chr17:36,348,023...36,353,635
Ensembl chr17:36,348,020...36,353,639

G

histocompatibility 2, T region locus 23

increases expression

fumonisin B1 results in increased expression of H2-T23 mRNA

NCBI chr17:36,340,869...36,343,593
Ensembl chr17:36,340,665...36,343,747

G

H2A.X variant histone

decreases expression

fumonisin B1 results in decreased expression of H2AX protein

NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374

G

H3.3 histone B

increases expression

fumonisin B1 results in increased expression of H3F3B mRNA

NCBI chr11:115,912,787...115,921,313
Ensembl chr11:115,912,738...115,918,788

G

hydroxyacyl glutathione hydrolase

decreases expression

fumonisin B1 results in decreased expression of HAGH mRNA

NCBI chr17:25,056,863...25,083,424
Ensembl chr17:25,059,117...25,083,424

G

histidine ammonia lyase

decreases expression

fumonisin B1 results in decreased expression of HAL mRNA

NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166

G

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

decreases expression

fumonisin B1 results in decreased expression of HMGCS2 mRNA

NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054

G

heme oxygenase 1

increases expression

fumonisin B1 results in increased expression of HMOX1 mRNA

NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217

G

hypoxanthine phosphoribosyltransferase 1

increases expression

fumonisin B1 results in increased expression of HPRT1 mRNA

NCBI chr X:52,076,955...52,110,537
Ensembl chr X:52,077,014...52,110,536

G

hemopexin

increases expression

fumonisin B1 results in increased expression of HPX mRNA

NCBI chr 7:105,240,818...105,249,323
Ensembl chr 7:105,240,820...105,249,344

G

hydroxysteroid 11-beta dehydrogenase 1

decreases expression

fumonisin B1 results in decreased expression of HSD11B1 mRNA

NCBI chr 1:192,903,917...192,946,345
Ensembl chr 1:192,903,942...192,946,383

G

hydroxysteroid (17-beta) dehydrogenase 10

decreases expression

fumonisin B1 results in decreased expression of HSD17B10 mRNA

NCBI chr X:150,784,892...150,787,438
Ensembl chr X:150,784,841...150,787,438

G

heat shock protein 5

multiple interactions
increases expression

4-phenylbutyric acid inhibits the reaction [fumonisin B1 results in increased expression of HSPA5 protein]; thermozymocidin inhibits the reaction [fumonisin B1 results in increased expression of HSPA5 protein]
fumonisin B1 results in increased expression of HSPA5 mRNA; fumonisin B1 results in increased expression of HSPA5 protein

NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559

G

isopentenyl-diphosphate delta isomerase

decreases expression

fumonisin B1 results in decreased expression of IDI1 mRNA

NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487

G

interferon gamma

increases expression
affects expression
multiple interactions

fumonisin B1 results in increased expression of IFNG mRNA
fumonisin B1 affects the expression of IFNG mRNA
5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IFNG mRNA]; S-Adenosylmethionine inhibits the reaction [fumonisin B1 results in increased expression of IFNG mRNA]

PMID:15590129 PMID:17080400 PMID:35697133

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

G

insulin-like growth factor 1

decreases expression

fumonisin B1 results in decreased expression of IGF1 mRNA

NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904

G

insulin-like growth factor binding protein, acid labile subunit

decreases expression

fumonisin B1 results in decreased expression of IGFALS mRNA

NCBI chr17:25,096,818...25,100,985
Ensembl chr17:25,084,971...25,100,984

G

insulin-like growth factor binding protein 1

increases expression

fumonisin B1 results in increased expression of IGFBP1 mRNA

NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546

G

interleukin 12a

increases expression

fumonisin B1 results in increased expression of IL12A mRNA

NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880

G

interleukin 18

multiple interactions
increases expression
increases secretion

deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL18 mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL18 protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased secretion of IL18 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL18 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL18 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased secretion of IL18 protein]
fumonisin B1 results in increased expression of IL18 mRNA; fumonisin B1 results in increased expression of IL18 protein

NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140

G

interleukin 1 alpha

increases expression

fumonisin B1 results in increased expression of IL1A mRNA

NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892

G

interleukin 1 beta

multiple interactions
increases expression
decreases expression
increases secretion

5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL1B protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased secretion of IL1B protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased secretion of IL1B protein]; S-Adenosylmethionine inhibits the reaction [fumonisin B1 results in increased expression of IL1B mRNA]
fumonisin B1 results in increased expression of IL1B mRNA; fumonisin B1 results in increased expression of IL1B protein
fumonisin B1 results in decreased expression of IL1B mRNA

PMID:17080400 PMID:35697133 PMID:36309173

NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059

G

interleukin 1 receptor antagonist

increases expression

fumonisin B1 results in increased expression of IL1RN mRNA

NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506

G

interleukin 2

increases expression
affects expression
multiple interactions

fumonisin B1 results in increased expression of IL2 mRNA
fumonisin B1 affects the expression of IL2 mRNA
5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IL2 mRNA]; S-Adenosylmethionine inhibits the reaction [fumonisin B1 results in increased expression of IL2 mRNA]

PMID:17080400 PMID:35697133

NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108

G

interleukin 6

increases expression
multiple interactions

fumonisin B1 results in increased expression of IL6 mRNA
5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IL6 mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL6 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; S-Adenosylmethionine inhibits the reaction [fumonisin B1 results in increased expression of IL6 mRNA]

PMID:17080400 PMID:27757495 PMID:36309173

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

G

indolethylamine N-methyltransferase

decreases expression

fumonisin B1 results in decreased expression of INMT mRNA

NCBI chr 6:55,147,612...55,151,975
Ensembl chr 6:55,147,611...55,152,028

G

inter-alpha trypsin inhibitor, heavy chain 1

decreases expression

fumonisin B1 results in decreased expression of ITIH1 mRNA

NCBI chr14:30,651,137...30,665,246
Ensembl chr14:30,651,137...30,665,246

G

inter alpha-trypsin inhibitor, heavy chain 4

decreases expression

fumonisin B1 results in decreased expression of ITIH4 mRNA

NCBI chr14:30,608,433...30,623,943
Ensembl chr14:30,608,433...30,624,310

G

isovaleryl coenzyme A dehydrogenase

decreases expression

fumonisin B1 results in decreased expression of IVD mRNA

NCBI chr 2:118,692,475...118,713,388
Ensembl chr 2:118,692,435...118,713,390

G

jun D proto-oncogene

increases expression

fumonisin B1 results in increased expression of JUND mRNA

NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265

G

lysine demethylase 5B

increases expression

fumonisin B1 results in increased expression of KDM5B mRNA

NCBI chr 1:134,487,916...134,560,621
Ensembl chr 1:134,487,909...134,563,023

G

lysine demethylase 5C

increases expression

fumonisin B1 results in increased expression of KDM5C mRNA

NCBI chr X:151,015,698...151,062,098
Ensembl chr X:151,016,016...151,057,531

G

kinase insert domain protein receptor

multiple interactions

fumonisin B1 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased phosphorylation of and results in decreased activity of KDR protein]; fumonisin B1 inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC results in decreased phosphorylation of and results in decreased activity of KDR protein]

NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118

G

kelch-like ECH-associated protein 1

decreases expression
multiple interactions
increases methylation

fumonisin B1 results in decreased expression of KEAP1 mRNA; fumonisin B1 results in decreased expression of KEAP1 protein
[fumonisin B1 results in increased methylation of KEAP1 promoter] which results in decreased expression of KEAP1 mRNA

PMID:33496827 PMID:35697133

NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657

G

kidney expressed gene 1

decreases expression

fumonisin B1 results in decreased expression of KEG1 mRNA

NCBI chr19:12,673,154...12,697,266
Ensembl chr19:12,673,150...12,697,266

G

kit ligand

decreases expression

fumonisin B1 results in decreased expression of KITLG mRNA

NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278

G

Kruppel-like transcription factor 6

increases expression

fumonisin B1 results in increased expression of KLF6 mRNA

NCBI chr13:5,911,488...5,920,392
Ensembl chr13:5,911,481...5,920,393

G

keratin 18

increases expression

fumonisin B1 results in increased expression of KRT18 mRNA

NCBI chr15:101,936,651...101,940,461
Ensembl chr15:101,936,615...101,940,462

G

keratin 8

increases expression

fumonisin B1 results in increased expression of KRT8 mRNA

NCBI chr15:101,905,146...101,912,777
Ensembl chr15:101,905,133...101,912,917

G

lysosomal-associated membrane protein 1

increases expression

fumonisin B1 results in increased expression of LAMP1 mRNA

NCBI chr 8:13,209,161...13,225,338
Ensembl chr 8:13,209,161...13,225,338

G

LIM and SH3 protein 1

increases expression

fumonisin B1 results in increased expression of LASP1 mRNA

NCBI chr11:97,689,748...97,729,591
Ensembl chr11:97,689,826...97,729,590

G

lecithin cholesterol acyltransferase

decreases expression

fumonisin B1 results in decreased expression of LCAT mRNA

NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014

G

LIF receptor alpha

decreases expression

fumonisin B1 results in decreased expression of LIFR mRNA

NCBI chr15:7,120,091...7,226,970
Ensembl chr15:7,120,095...7,226,970

G

LPS-induced TN factor

increases expression

fumonisin B1 results in increased expression of LITAF mRNA

NCBI chr16:10,777,137...10,810,985
Ensembl chr16:10,777,139...10,884,021

G

lamin A

increases expression

fumonisin B1 results in increased expression of LMNA mRNA

NCBI chr 3:88,388,455...88,413,842
Ensembl chr 3:88,387,454...88,417,263

G

lipoprotein lipase

increases expression

fumonisin B1 results in increased expression of LPL mRNA

NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100

G

lactoperoxidase

decreases expression

fumonisin B1 results in decreased expression of LPO mRNA

NCBI chr11:87,697,254...87,716,750
Ensembl chr11:87,697,254...87,719,115

G

lipolysis stimulated lipoprotein receptor

increases expression

fumonisin B1 results in increased expression of LSR mRNA

NCBI chr 7:30,657,195...30,672,894
Ensembl chr 7:30,657,195...30,672,889

G

lymphotoxin B

increases expression
multiple interactions

fumonisin B1 results in increased expression of LTB mRNA
5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of LTB mRNA]; S-Adenosylmethionine inhibits the reaction [fumonisin B1 results in increased expression of LTB mRNA]

PMID:15590129 PMID:17080400

NCBI chr17:35,413,483...35,415,281
Ensembl chr17:35,413,415...35,415,296

G

lymphotoxin B receptor

decreases expression

fumonisin B1 results in decreased expression of LTBR mRNA

NCBI chr 6:125,283,534...125,291,026
Ensembl chr 6:125,283,534...125,290,848

G

lymphocyte antigen 6 family member E

increases expression

fumonisin B1 results in increased expression of LY6E mRNA

NCBI chr15:74,826,874...74,831,753
Ensembl chr15:74,826,900...74,831,752

G

lysozyme 1

increases expression

fumonisin B1 results in increased expression of LYZ1 mRNA

NCBI chr10:117,123,700...117,128,773
Ensembl chr10:117,123,702...117,128,773

G

lysozyme 2

increases expression

fumonisin B1 results in increased expression of LYZ2 mRNA

NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226

G

mannosidase 2, alpha B1

increases expression

fumonisin B1 results in increased expression of MAN2B1 mRNA

NCBI chr 8:85,809,941...85,824,215
Ensembl chr 8:85,809,899...85,824,911

G

macrophage receptor with collagenous structure

increases expression

fumonisin B1 results in increased expression of MARCO mRNA

NCBI chr 1:120,402,267...120,432,753
Ensembl chr 1:120,402,267...120,432,753

G

methyl-CpG binding domain protein 2

multiple interactions

fumonisin B1 results in increased expression of and results in increased activity of MBD2 protein

NCBI chr18:70,701,298...70,761,769
Ensembl chr18:70,701,260...70,759,202

G

mannose-binding lectin (protein A) 1

decreases expression

fumonisin B1 results in decreased expression of MBL1 mRNA

NCBI chr14:40,873,413...40,885,861
Ensembl chr14:40,873,415...40,881,558

G

transformed mouse 3T3 cell double minute 2

multiple interactions

fumonisin B1 inhibits the reaction [AGT protein results in increased expression of MDM2 mRNA]; fumonisin B1 inhibits the reaction [AGT protein results in increased expression of MDM2 protein]

NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663

G

methyltransferase 14, N6-adenosine-methyltransferase subunit

increases expression

fumonisin B1 results in increased expression of METTL14 mRNA

NCBI chr 3:123,161,944...123,179,639
Ensembl chr 3:123,161,946...123,179,757

G

methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

increases expression

fumonisin B1 results in increased expression of METTL3 mRNA

NCBI chr14:52,532,298...52,548,555
Ensembl chr14:52,532,298...52,542,585

G

microRNA 27b

decreases expression
multiple interactions

fumonisin B1 results in decreased expression of MIR27B mRNA
[fumonisin B1 results in decreased expression of MIR27B mRNA] which results in increased expression of NFE2L2 mRNA; [fumonisin B1 results in decreased expression of MIR27B mRNA] which results in increased expression of NFE2L2 protein; MIR27B mRNA inhibits the reaction [fumonisin B1 results in increased expression of NFE2L2 mRNA]; MIR27B mRNA inhibits the reaction [fumonisin B1 results in increased expression of NFE2L2 protein]

PMID:24614526 PMID:33496827

NCBI chr13:63,448,526...63,448,598
Ensembl chr13:63,448,526...63,448,598

G

methylsterol monoxygenase 1

decreases expression

fumonisin B1 results in decreased expression of MSMO1 mRNA

NCBI chr 8:65,171,157...65,186,822
Ensembl chr 8:65,171,173...65,186,826

G

methionine sulfoxide reductase B1

decreases expression

fumonisin B1 results in decreased expression of MSRB1 mRNA

NCBI chr17:24,955,567...24,961,752
Ensembl chr17:24,955,616...24,961,752

G

metallothionein 1

decreases expression

fumonisin B1 results in decreased expression of MT1 mRNA

NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955

G

metallothionein 2

decreases expression

fumonisin B1 results in decreased expression of MT2 mRNA

NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196

G

mechanistic target of rapamycin kinase

decreases expression

fumonisin B1 results in decreased expression of MTOR mRNA

NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140

G

mucin 5, subtypes A and C, tracheobronchial/gastric

multiple interactions
increases expression

fumonisin B1 results in increased expression of and results in increased secretion of MUC5AC protein
fumonisin B1 results in increased expression of MUC5AC mRNA

NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968

G

mucin 5, subtype B, tracheobronchial

multiple interactions
increases expression

fumonisin B1 results in increased expression of and results in increased secretion of MUC5B protein
fumonisin B1 results in increased expression of MUC5B mRNA

NCBI chr 7:141,392,796...141,426,826
Ensembl chr 7:141,392,807...141,426,821

G

major urinary protein 1

decreases expression

fumonisin B1 results in decreased expression of MUP1 mRNA

NCBI chr 4:60,454,011...60,457,959
Ensembl chr 4:60,454,011...60,457,959

G

major urinary protein 3

decreases expression

fumonisin B1 results in decreased expression of MUP3 mRNA

NCBI chr 4:62,001,713...62,005,554
Ensembl chr 4:62,001,713...62,005,579

G

major urinary protein 4

decreases expression

fumonisin B1 results in decreased expression of MUP4 mRNA

NCBI chr 4:59,956,804...59,960,667
Ensembl chr 4:59,956,804...59,960,710

G

myosin, heavy polypeptide 9, non-muscle

increases expression

fumonisin B1 results in increased expression of MYH9 mRNA

NCBI chr15:77,644,788...77,726,315
Ensembl chr15:77,644,787...77,726,375

G

myosin IC

increases expression

fumonisin B1 results in increased expression of MYO1C mRNA

NCBI chr11:75,541,345...75,565,450
Ensembl chr11:75,541,330...75,564,736

G

N-acetyltransferase 8 (GCN5-related) family member 1

decreases expression

fumonisin B1 results in decreased expression of NAT8F1 mRNA

NCBI chr 6:85,887,136...85,893,210
Ensembl chr 6:85,887,136...85,892,669

G

NADH:ubiquinone oxidoreductase subunit B10

decreases expression

fumonisin B1 results in decreased expression of NDUFB10 mRNA

NCBI chr17:24,941,034...24,943,397
Ensembl chr17:24,941,034...24,943,452

G

NADH:ubiquinone oxidoreductase subunit B11

decreases expression

fumonisin B1 results in decreased expression of NDUFB11 mRNA

NCBI chr X:20,481,565...20,483,858
Ensembl chr X:20,481,565...20,483,858

G

nuclear factor, erythroid derived 2, like 2

increases expression
affects expression
decreases methylation
multiple interactions
increases methylation

fumonisin B1 results in increased expression of NFE2L2 mRNA
fumonisin B1 affects the expression of NFE2L2 mRNA
fumonisin B1 results in increased expression of NFE2L2 mRNA; fumonisin B1 results in increased expression of NFE2L2 protein
fumonisin B1 results in decreased methylation of NFE2L2 promoter
[fumonisin B1 results in decreased expression of MIR27B mRNA] which results in increased expression of NFE2L2 mRNA; [fumonisin B1 results in decreased expression of MIR27B mRNA] which results in increased expression of NFE2L2 protein; [fumonisin B1 results in decreased methylation of NFE2L2 promoter] which results in increased expression of NFE2L2 mRNA; MIR27B mRNA inhibits the reaction [fumonisin B1 results in increased expression of NFE2L2 mRNA]; MIR27B mRNA inhibits the reaction [fumonisin B1 results in increased expression of NFE2L2 protein]
fumonisin B1 results in increased methylation of NFE2L2 mRNA

PMID:16221962 PMID:33496827 PMID:35697133

NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985

G

NLR family, pyrin domain containing 3

multiple interactions
increases expression

deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of NLRP3 mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of NLRP3 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of NLRP3 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of NLRP3 protein]
fumonisin B1 results in increased expression of NLRP3 mRNA; fumonisin B1 results in increased expression of NLRP3 protein

NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782

G

nicotinamide N-methyltransferase

decreases expression

fumonisin B1 results in decreased expression of NNMT mRNA

NCBI chr 9:48,448,905...48,518,958
Ensembl chr 9:48,503,177...48,516,453

G

NAD(P)H dehydrogenase, quinone 1

affects expression

fumonisin B1 affects the expression of NQO1 mRNA

NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838

G

nuclear receptor subfamily 1, group H, member 2

affects response to substance
multiple interactions

NR1H2 protein affects the susceptibility to fumonisin B1
[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of ABCG8 mRNA; [NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of CD63 mRNA; [NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of COL1A1 mRNA; [NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of COL3A1 mRNA; [NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of CXCL14 mRNA; [NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of CYP7B1 mRNA; [NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of ELOVL7 mRNA; [NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of GPT protein; [NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of RAB7B mRNA; [NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of SMPD3 mRNA; [NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of TM7SF2 mRNA; [NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of UGT2B1 mRNA

NCBI chr 7:44,199,040...44,204,928
Ensembl chr 7:44,199,040...44,203,375

G

nuclear receptor subfamily 1, group H, member 3

multiple interactions
affects response to substance

[NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of ABCG8 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of CD63 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of COL1A1 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of COL3A1 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of CXCL14 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of CYP7B1 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of ELOVL7 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of GPT protein; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of RAB7B mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of SMPD3 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of TM7SF2 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of UGT2B1 mRNA

NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179

G

nuclear receptor subfamily 1, group I, member 3

decreases expression

fumonisin B1 results in decreased expression of NR1I3 mRNA

NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270

G

nuclear receptor subfamily 3, group C, member 1

decreases expression

fumonisin B1 results in decreased expression of NR3C1 mRNA

NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474

G

NAD(P) dependent steroid dehydrogenase-like

decreases expression

fumonisin B1 results in decreased expression of NSDHL mRNA

NCBI chr X:71,962,127...72,002,134
Ensembl chr X:71,962,163...72,002,120

G

ornithine aminotransferase

decreases expression

fumonisin B1 results in decreased expression of OAT mRNA

NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127

G

occludin

multiple interactions
decreases expression

illite inhibits the reaction [fumonisin B1 results in decreased expression of OCLN mRNA]

NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226

G

oligodendrocyte transcription factor 2

decreases expression

fumonisin B1 results in decreased expression of OLIG2 mRNA

NCBI chr16:91,016,745...91,025,567
Ensembl chr16:91,022,345...91,025,565

G

poly (ADP-ribose) polymerase family, member 1

multiple interactions
decreases cleavage

fumonisin B1 inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]
fumonisin B1 results in decreased cleavage of PARP1 protein

PMID:24448832 PMID:25800559

NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819

G

poly(rC) binding protein 1

increases expression

fumonisin B1 results in increased expression of PCBP1 mRNA

NCBI chr 6:86,501,462...86,503,171
Ensembl chr 6:86,501,474...86,503,303

G

pyruvate carboxylase

decreases expression

fumonisin B1 results in decreased expression of PCX mRNA

NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780

G

platelet derived growth factor, alpha

increases expression

fumonisin B1 results in increased expression of PDGFA mRNA

NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125

G

PDZ and LIM domain 1 (elfin)

increases expression

fumonisin B1 results in increased expression of PDLIM1 mRNA

NCBI chr19:40,210,683...40,260,060
Ensembl chr19:40,209,617...40,260,286

G

pleckstrin homology like domain, family A, member 1

decreases expression

fumonisin B1 results in decreased expression of PHLDA1 mRNA

NCBI chr10:111,342,147...111,344,510
Ensembl chr10:111,342,147...111,344,506

G

polymeric immunoglobulin receptor

decreases expression

fumonisin B1 results in decreased expression of PIGR mRNA

NCBI chr 1:130,754,421...130,779,986
Ensembl chr 1:130,754,421...130,779,986

G

pipecolic acid oxidase

decreases expression

fumonisin B1 results in decreased expression of PIPOX mRNA

NCBI chr11:77,771,440...77,784,698
Ensembl chr11:77,771,441...77,784,922

G

perilipin 2

increases expression

fumonisin B1 results in increased expression of PLIN2 mRNA

NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297

G

phospholipid transfer protein

increases expression

fumonisin B1 results in increased expression of PLTP mRNA

NCBI chr 2:164,681,441...164,699,564
Ensembl chr 2:164,681,438...164,699,631

G

paraoxonase 1

decreases expression

fumonisin B1 results in decreased expression of PON1 mRNA

NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946

G

peroxisome proliferator activated receptor alpha

decreases expression

fumonisin B1 results in decreased expression of PPARA mRNA

NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020

G

peptidylprolyl isomerase A

increases expression

fumonisin B1 results in increased expression of PPIA mRNA

NCBI chr11:6,365,867...6,369,817
Ensembl chr11:6,365,443...6,369,817

G

protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform

multiple interactions

fumonisin B1 inhibits the reaction [Ethanol results in increased activity of PPP2CA protein]

NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605

G

peroxiredoxin 6

decreases expression

fumonisin B1 results in decreased expression of PRDX6 mRNA

NCBI chr 1:161,067,682...161,078,780
Ensembl chr 1:161,067,682...161,078,789

G

prolactin receptor

decreases expression

fumonisin B1 results in decreased expression of PRLR mRNA

NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266

G

proline dehydrogenase (oxidase) 2

decreases expression

fumonisin B1 results in decreased expression of PRODH2 mRNA

NCBI chr 7:30,193,011...30,212,830
Ensembl chr 7:30,193,047...30,212,827

G

pre-mRNA processing factor 8

decreases expression

fumonisin B1 results in decreased expression of PRPF8 mRNA

NCBI chr11:75,377,603...75,400,273
Ensembl chr11:75,377,642...75,400,275

G

proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

increases expression

fumonisin B1 results in increased expression of PSMD8 mRNA

NCBI chr 7:28,873,612...28,880,098
Ensembl chr 7:28,873,613...28,880,126

G

protein tyrosine phosphatase 4a1

increases expression

fumonisin B1 results in increased expression of PTP4A1 mRNA

NCBI chr 1:30,979,384...30,988,838
Ensembl chr 1:30,979,383...30,988,390
Ensembl chr 1:30,979,383...30,988,390

G

peroxisomal membrane protein 2

decreases expression

fumonisin B1 results in decreased expression of PXMP2 mRNA

NCBI chr 5:110,422,152...110,434,036
Ensembl chr 5:110,422,148...110,434,052

G

PYD and CARD domain containing

multiple interactions

[deoxynivalenol co-treated with fumonisin B1] results in increased expression of PYCARD mRNA; [deoxynivalenol co-treated with fumonisin B1] results in increased expression of PYCARD protein

NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039

G

quinoid dihydropteridine reductase

decreases expression

fumonisin B1 results in decreased expression of QDPR mRNA

NCBI chr 5:45,591,374...45,607,571
Ensembl chr 5:45,591,363...45,607,578

G

RAB7B, member RAS oncogene family

multiple interactions

[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of RAB7B mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of RAB7B mRNA

NCBI chr 1:131,616,412...131,646,288
Ensembl chr 1:131,616,433...131,643,177

G

v-rel reticuloendotheliosis viral oncogene homolog A (avian)

decreases expression

fumonisin B1 results in decreased expression of RELA mRNA

NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158

G

regucalcin

decreases expression

fumonisin B1 results in decreased expression of RGN mRNA

NCBI chr X:20,413,980...20,428,328
Ensembl chr X:20,416,026...20,428,328

G

regulator of G-protein signaling 16

decreases expression

fumonisin B1 results in decreased expression of RGS16 mRNA

NCBI chr 1:153,616,099...153,621,212
Ensembl chr 1:153,616,095...153,621,214

G

ras homolog family member C

increases expression

fumonisin B1 results in increased expression of RHOC mRNA

NCBI chr 3:104,696,350...104,701,775
Ensembl chr 3:104,695,691...104,701,775

G

ras homolog family member Q

increases expression

fumonisin B1 results in increased expression of RHOQ mRNA

NCBI chr17:87,270,539...87,307,497
Ensembl chr17:87,270,510...87,307,497

G

ras homolog family member U

increases expression

fumonisin B1 results in increased expression of RHOU mRNA

NCBI chr 8:124,380,609...124,390,622
Ensembl chr 8:124,380,668...124,390,623

G

ring finger protein 11

increases expression

fumonisin B1 results in increased expression of RNF11 mRNA

NCBI chr 4:109,310,054...109,333,702
Ensembl chr 4:109,308,295...109,341,925

G

ribosomal protein S12

increases expression

fumonisin B1 results in increased expression of RPS12 mRNA

NCBI chr10:23,661,042...23,664,297
Ensembl chr10:23,661,081...23,663,173

G

S100 calcium binding protein A10 (calpactin)

increases expression

fumonisin B1 results in increased expression of S100A10 mRNA

NCBI chr 3:93,462,424...93,471,952
Ensembl chr 3:93,462,387...93,471,950

G

S100 calcium binding protein A11

increases expression

fumonisin B1 results in increased expression of S100A11 mRNA

NCBI chr 3:93,427,803...93,433,595
Ensembl chr 3:93,427,795...93,433,594

G

serum amyloid A 2

decreases expression

fumonisin B1 results in decreased expression of SAA2 mRNA

NCBI chr 7:46,401,257...46,403,737
Ensembl chr 7:46,401,214...46,403,737

G

sarcosine dehydrogenase

decreases expression

fumonisin B1 results in decreased expression of SARDH mRNA

NCBI chr 2:27,078,405...27,138,344
Ensembl chr 2:27,078,405...27,138,349

G

spermidine/spermine N1-acetyl transferase 1

increases expression

fumonisin B1 results in increased expression of SAT1 mRNA

NCBI chr X:153,996,128...153,999,345
Ensembl chr X:153,996,128...153,999,445

G

serine incorporator 1

increases expression

fumonisin B1 results in increased expression of SERINC1 mRNA

NCBI chr10:57,391,870...57,408,573
Ensembl chr10:57,391,870...57,408,626

G

serine incorporator 3

increases expression

fumonisin B1 results in increased expression of SERINC3 mRNA

NCBI chr 2:163,466,577...163,487,767
Ensembl chr 2:163,465,192...163,487,051

G

serine (or cysteine) peptidase inhibitor, clade A, member 1A

decreases expression

fumonisin B1 results in decreased expression of SERPINA1A mRNA

NCBI chr12:103,819,554...103,829,878
Ensembl chr12:103,819,848...103,829,821

G

serine (or cysteine) preptidase inhibitor, clade A, member 1B

decreases expression

fumonisin B1 results in decreased expression of SERPINA1B mRNA

NCBI chr12:103,694,415...103,704,448
Ensembl chr12:103,694,415...103,796,632

G

serine (or cysteine) peptidase inhibitor, clade A, member 1C

decreases expression

fumonisin B1 results in decreased expression of SERPINA1C mRNA

NCBI chr12:103,861,185...103,871,209
Ensembl chr12:103,861,185...103,871,146

G

serine (or cysteine) peptidase inhibitor, clade A, member 1E

decreases expression

fumonisin B1 results in decreased expression of SERPINA1E mRNA

NCBI chr12:103,913,190...103,923,156
Ensembl chr12:103,913,190...103,925,234

G

serine (or cysteine) peptidase inhibitor, clade A, member 3C

decreases expression

fumonisin B1 results in decreased expression of SERPINA3C mRNA

NCBI chr12:104,113,166...104,120,187
Ensembl chr12:104,112,641...104,120,129

G

serine (or cysteine) peptidase inhibitor, clade A, member 3M

decreases expression

fumonisin B1 results in decreased expression of SERPINA3M mRNA

NCBI chr12:104,353,424...104,360,518
Ensembl chr12:104,304,745...104,360,516

G

serine (or cysteine) peptidase inhibitor, clade A, member 6

decreases expression

fumonisin B1 results in decreased expression of SERPINA6 mRNA

NCBI chr12:103,612,889...103,623,477
Ensembl chr12:103,612,889...103,623,471

G

serine (or cysteine) peptidase inhibitor, clade B, member 6a

increases expression

fumonisin B1 results in increased expression of SERPINB6 mRNA

NCBI chr13:34,101,901...34,186,777
Ensembl chr13:34,101,901...34,186,777

G

serine (or cysteine) peptidase inhibitor, clade E, member 1

multiple interactions

fumonisin B1 inhibits the reaction [Daunorubicin results in decreased expression of SERPINE1 protein]

NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122

G

serine (or cysteine) peptidase inhibitor, clade G, member 1

decreases expression

fumonisin B1 results in decreased expression of SERPING1 mRNA

NCBI chr 2:84,595,704...84,605,748
Ensembl chr 2:84,595,731...84,605,788

G

surfactant associated protein A1

increases expression

fumonisin B1 results in increased expression of SFTPA1 mRNA

NCBI chr14:40,853,745...40,858,330
Ensembl chr14:40,853,739...40,858,409

G

surfactant associated protein D

increases expression

fumonisin B1 results in increased expression of SFTPD mRNA

NCBI chr14:40,894,169...40,907,155
Ensembl chr14:40,894,171...40,907,106

G

SH3 and multiple ankyrin repeat domains 2

decreases expression

fumonisin B1 results in decreased expression of SHANK2 mRNA

NCBI chr 7:143,531,819...143,979,780
Ensembl chr 7:143,555,665...143,978,231

G

serine hydroxymethyltransferase 1 (soluble)

decreases expression

fumonisin B1 results in decreased expression of SHMT1 mRNA

NCBI chr11:60,679,723...60,702,062
Ensembl chr11:60,678,930...60,702,544

G

solute carrier family 10 (sodium/bile acid cotransporter family), member 1

decreases expression

fumonisin B1 results in decreased expression of SLC10A1 mRNA

NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479

G

solute carrier family 20, member 1

increases expression

fumonisin B1 results in increased expression of SLC20A1 mRNA

NCBI chr 2:129,038,662...129,053,535
Ensembl chr 2:129,040,684...129,053,536

G

solute carrier family 22 (organic cation transporter), member 1

decreases expression

fumonisin B1 results in decreased expression of SLC22A1 mRNA

NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716

G

solute carrier family 22 (organic cation transporter), member 18

increases expression

fumonisin B1 results in increased expression of SLC22A18 mRNA

NCBI chr 7:143,027,502...143,053,071
Ensembl chr 7:143,027,473...143,053,071

G

solute carrier family 27 (fatty acid transporter), member 2

decreases expression

fumonisin B1 results in decreased expression of SLC27A2 mRNA

NCBI chr 2:126,394,944...126,430,163
Ensembl chr 2:126,394,327...126,430,163

G

solute carrier family 27 (fatty acid transporter), member 5

decreases expression

fumonisin B1 results in decreased expression of SLC27A5 mRNA

NCBI chr 7:12,722,273...12,732,119
Ensembl chr 7:12,722,273...12,732,119

G

solute carrier family 29 (nucleoside transporters), member 1

decreases expression

fumonisin B1 results in decreased expression of SLC29A1 mRNA

NCBI chr17:45,896,126...45,910,544
Ensembl chr17:45,896,126...45,910,532

G

solute carrier family 31, member 1

decreases expression

fumonisin B1 results in decreased expression of SLC31A1 mRNA

NCBI chr 4:62,278,821...62,310,006
Ensembl chr 4:62,278,964...62,310,006

G

solute carrier family 37 (glucose-6-phosphate transporter), member 4

decreases expression

fumonisin B1 results in decreased expression of SLC37A4 mRNA

NCBI chr 9:44,308,243...44,314,263
Ensembl chr 9:44,308,149...44,314,265

G

solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12

decreases expression

fumonisin B1 results in decreased expression of SLC6A12 mRNA

NCBI chr 6:121,319,533...121,342,732
Ensembl chr 6:121,320,035...121,342,734

G

solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

decreases expression

fumonisin B1 results in decreased expression of SLC6A4 mRNA

NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166

G

sphingomyelin phosphodiesterase 3, neutral

multiple interactions

[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of SMPD3 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of SMPD3 mRNA

NCBI chr 8:106,979,180...107,064,597
Ensembl chr 8:106,979,180...107,064,620

G

sorting nexin 3

increases expression

fumonisin B1 results in increased expression of SNX3 mRNA

NCBI chr10:42,378,050...42,411,365
Ensembl chr10:42,378,026...42,411,377

G

superoxide dismutase 1, soluble

increases expression

fumonisin B1 results in increased expression of SOD1 mRNA

NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217

G

sphingosine kinase 1

multiple interactions

fumonisin B1 inhibits the reaction [Particulate Matter results in increased expression of SPHK1 mRNA]; fumonisin B1 inhibits the reaction [Vehicle Emissions results in increased expression of SPHK1 mRNA]

NCBI chr11:116,421,662...116,427,502
Ensembl chr11:116,421,751...116,427,501

G

small proline-rich protein 1A

increases expression

fumonisin B1 results in increased expression of SPRR1A mRNA

NCBI chr 3:92,391,261...92,393,188
Ensembl chr 3:92,391,259...92,393,202

G

spectrin alpha, non-erythrocytic 1

increases expression

fumonisin B1 results in increased expression of SPTAN1 mRNA

NCBI chr 2:29,855,572...29,921,463
Ensembl chr 2:29,855,572...29,921,463

G

spectrin beta, non-erythrocytic 1

increases expression

fumonisin B1 results in increased expression of SPTBN1 mRNA

NCBI chr11:30,049,395...30,218,384
Ensembl chr11:30,049,395...30,218,175

G

sequestosome 1

increases expression

fumonisin B1 results in increased expression of SQSTM1 mRNA

NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654

G

sterol regulatory element binding transcription factor 1

decreases expression

fumonisin B1 results in decreased expression of SREBF1 mRNA

NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407

G

sulfiredoxin 1 homolog (S. cerevisiae)

increases expression

fumonisin B1 results in increased expression of SRXN1 mRNA

NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296

G

SS18, nBAF chromatin remodeling complex subunit like 2

decreases expression

fumonisin B1 results in decreased expression of SS18L2 mRNA

NCBI chr 9:121,539,455...121,541,987
Ensembl chr 9:121,539,395...121,542,454

G

succinate-Coenzyme A ligase, GDP-forming, beta subunit

decreases expression

fumonisin B1 results in decreased expression of SUCLG2 mRNA

NCBI chr 6:95,449,992...95,695,799
Ensembl chr 6:95,449,990...95,695,781

G

sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2

decreases expression

fumonisin B1 results in decreased expression of SULT2A2 mRNA

NCBI chr 7:13,467,431...13,513,562
Ensembl chr 7:13,467,430...13,513,561

G

sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 7

decreases expression

fumonisin B1 results in decreased expression of SULT2A7 mRNA

NCBI chr 7:14,198,976...14,226,948
Ensembl chr 7:14,198,976...14,228,155

G

sulfotransferase family 3A, member 1

decreases expression

fumonisin B1 results in decreased expression of SULT3A1 mRNA

NCBI chr10:33,727,016...33,755,471
Ensembl chr10:33,733,717...33,755,528

G

sulfotransferase family 5A, member 1

decreases expression

fumonisin B1 results in decreased expression of SULT5A1 mRNA

NCBI chr 8:123,869,582...123,885,170
Ensembl chr 8:123,866,931...123,885,054

G

transgelin 2

increases expression

fumonisin B1 results in increased expression of TAGLN2 mRNA

NCBI chr 1:172,327,813...172,334,942
Ensembl chr 1:172,327,614...172,334,947

G

tryptophan 2,3-dioxygenase

decreases expression

fumonisin B1 results in decreased expression of TDO2 mRNA

NCBI chr 3:81,865,719...81,883,035
Ensembl chr 3:81,864,397...81,883,509

G

trefoil factor 2 (spasmolytic protein 1)

decreases expression

fumonisin B1 results in decreased expression of TFF2 mRNA

NCBI chr17:31,360,036...31,363,256
Ensembl chr17:31,360,023...31,363,256

G

transferrin receptor 2

decreases expression

fumonisin B1 results in decreased expression of TFR2 mRNA

NCBI chr 5:137,568,127...137,586,344
Ensembl chr 5:137,568,102...137,585,743

G

transforming growth factor, beta 1

increases expression

fumonisin B1 results in increased expression of TGFB1 mRNA

NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502

G

thyroid hormone responsive

decreases expression

fumonisin B1 results in decreased expression of THRSP mRNA

NCBI chr 7:97,062,140...97,066,757
Ensembl chr 7:97,062,145...97,066,937

G

transmembrane 7 superfamily member 2

multiple interactions

[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of TM7SF2 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of TM7SF2 mRNA

NCBI chr19:6,112,851...6,117,880
Ensembl chr19:6,112,851...6,118,403

G

transmembrane protein 176B

increases expression

fumonisin B1 results in increased expression of TMEM176B mRNA

NCBI chr 6:48,810,745...48,818,363
Ensembl chr 6:48,810,752...48,818,430

G

tumor necrosis factor

increases expression
decreases expression

fumonisin B1 results in increased expression of TNF mRNA
fumonisin B1 results in decreased expression of TNF mRNA; fumonisin B1 results in decreased expression of TNF protein

PMID:15590129 PMID:17080400 PMID:35697133

NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983

G

tumor necrosis factor receptor superfamily, member 1a

increases expression

fumonisin B1 results in increased expression of TNFRSF1A mRNA

NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447

G

tumor necrosis factor (ligand) superfamily, member 10

increases expression

fumonisin B1 results in increased expression of TNFSF10 mRNA

NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576

G

tropomyosin 1, alpha

increases expression

fumonisin B1 results in increased expression of TPM1 mRNA

NCBI chr 9:66,929,872...66,956,954
Ensembl chr 9:66,929,872...66,956,688

G

tripeptidyl peptidase I

increases expression

fumonisin B1 results in increased expression of TPP1 mRNA

NCBI chr 7:105,394,018...105,401,489
Ensembl chr 7:105,394,018...105,401,442

G

transformation related protein 53

multiple interactions
decreases expression
increases expression

[fumonisin B1 results in decreased chemical synthesis of Ceramides] which affects the splicing of and results in decreased expression of TP53 mRNA; [fumonisin B1 results in decreased chemical synthesis of Ceramides] which results in decreased phosphorylation of TP53 protein modified form
fumonisin B1 results in decreased expression of TP53 mRNA
fumonisin B1 results in increased expression of TP53 protein
Acetylcysteine inhibits the reaction [Aflatoxin B1 promotes the reaction [fumonisin B1 results in increased expression of TP53 protein]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Aflatoxin B1 results in increased expression of TP53 protein]]; Aflatoxin B1 promotes the reaction [fumonisin B1 results in increased expression of TP53 protein]; fumonisin B1 promotes the reaction [Aflatoxin B1 results in increased expression of TP53 protein]

PMID:25195822 PMID:27757495 PMID:28181396

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

G

translocator protein

increases expression

fumonisin B1 results in increased expression of TSPO mRNA

NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404

G

thiosulfate sulfurtransferase, mitochondrial

decreases expression

fumonisin B1 results in decreased expression of TST mRNA

NCBI chr15:78,283,756...78,290,065
Ensembl chr15:78,283,756...78,290,107

G

transthyretin

decreases expression

fumonisin B1 results in decreased expression of TTR mRNA

NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378

G

tubulin, beta 2A class IIA

increases expression

fumonisin B1 results in increased expression of TUBB2A mRNA

NCBI chr13:34,258,261...34,261,991
Ensembl chr13:34,258,257...34,261,990

G

tubulin, beta 3 class III

increases expression

fumonisin B1 results in increased expression of TUBB3 mRNA

NCBI chr 8:124,138,292...124,148,754
Ensembl chr 8:124,138,163...124,148,754

G

tubulin, beta 5 class I

increases expression

fumonisin B1 results in increased expression of TUBB5 mRNA

NCBI chr17:36,144,812...36,149,193
Ensembl chr17:36,144,813...36,149,198

G

thioredoxin 1

increases expression

fumonisin B1 results in increased expression of TXN1 mRNA

NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411

G

thioredoxin 2

decreases expression

fumonisin B1 results in decreased expression of TXN2 mRNA

NCBI chr15:77,799,251...77,813,194
Ensembl chr15:77,799,247...77,813,206

G

thymidine phosphorylase

decreases expression

fumonisin B1 results in decreased expression of TYMP mRNA

NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242

G

ubiquitin-conjugating enzyme E2N

increases expression

fumonisin B1 results in increased expression of UBE2N mRNA

NCBI chr10:95,351,024...95,381,520
Ensembl chr10:95,351,007...95,381,519

G

UDP-glucose ceramide glucosyltransferase

multiple interactions

fumonisin B1 inhibits the reaction [Doxorubicin results in increased expression of UGCG mRNA]

NCBI chr 4:59,189,452...59,222,833
Ensembl chr 4:59,189,257...59,222,833

G

UDP-glucose dehydrogenase

increases expression

fumonisin B1 results in increased expression of UGDH mRNA

NCBI chr 5:65,570,550...65,593,185
Ensembl chr 5:65,570,564...65,593,292

G

UDP glucuronosyltransferase 2 family, polypeptide B1

multiple interactions

[NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of UGT2B1 mRNA; [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of UGT2B1 mRNA

NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389

G

unc-51 like kinase 1

decreases expression

fumonisin B1 results in decreased expression of ULK1 mRNA

NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963

G

urate oxidase

decreases expression

fumonisin B1 results in decreased expression of UOX mRNA

NCBI chr 3:146,302,904...146,337,238
Ensembl chr 3:146,276,181...146,338,060

G

ubiquitin specific peptidase 15

decreases expression

fumonisin B1 results in decreased expression of USP15 mRNA

NCBI chr10:122,940,911...123,032,924
Ensembl chr10:122,940,911...123,032,900

G

ubiquitin specific peptidase 18

increases expression

fumonisin B1 results in increased expression of USP18 mRNA

NCBI chr 6:121,222,865...121,247,876
Ensembl chr 6:121,222,865...121,247,876

G

vesicle-associated membrane protein, associated protein A

increases expression

fumonisin B1 results in increased expression of VAPA mRNA

NCBI chr17:65,887,048...65,925,441
Ensembl chr17:65,885,322...65,920,550

G

vinculin

increases expression

fumonisin B1 results in increased expression of VCL mRNA

NCBI chr14:20,979,436...21,083,744
Ensembl chr14:20,979,466...21,083,744

G

vascular endothelial growth factor A

multiple interactions

fumonisin B1 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of and results in decreased secretion of VEGFA protein]; fumonisin B1 inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC results in decreased expression of and results in decreased secretion of VEGFA protein]

NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295

G

VPS35 retromer complex component

increases expression

fumonisin B1 results in increased expression of VPS35 mRNA

NCBI chr 8:85,987,014...86,026,146
Ensembl chr 8:85,987,021...86,026,431

G

YTH domain containing 2

increases expression

fumonisin B1 results in increased expression of YTHDC2 mRNA

NCBI chr18:44,961,521...45,022,782
Ensembl chr18:44,960,813...45,022,791

G

YTH N6-methyladenosine RNA binding protein 1

increases expression

fumonisin B1 results in increased expression of YTHDF1 mRNA

NCBI chr 2:180,546,170...180,562,729
Ensembl chr 2:180,546,170...180,562,742

G

YTH N6-methyladenosine RNA binding protein 2

increases expression

fumonisin B1 results in increased expression of YTHDF2 mRNA

NCBI chr 4:131,912,227...131,939,567
Ensembl chr 4:131,912,223...131,939,614

G

YTH N6-methyladenosine RNA binding protein 3

increases expression

fumonisin B1 results in increased expression of YTHDF3 mRNA

NCBI chr 3:16,237,309...16,271,201
Ensembl chr 3:16,237,376...16,271,201

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide

increases expression

fumonisin B1 results in increased expression of YWHAG mRNA

NCBI chr 5:135,937,233...135,963,495
Ensembl chr 5:135,937,263...135,963,470

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide

increases expression

fumonisin B1 results in increased expression of YWHAH mRNA

NCBI chr 5:33,176,160...33,185,310
Ensembl chr 5:33,176,160...33,185,310

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

increases expression

fumonisin B1 results in increased expression of YWHAZ mRNA

NCBI chr15:36,770,505...36,803,228
Ensembl chr15:36,771,014...36,797,173

G

zeta-chain (TCR) associated protein kinase

decreases expression

fumonisin B1 results in decreased expression of ZAP70 mRNA

NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899

fumonisin B2

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

peroxisome proliferator activated receptor gamma

decreases activity

fumonisin B2 results in decreased activity of PPARG protein

NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	22210
role	22195
biological role	22194
poison	19444
toxin	16257
mycotoxin	12169
fumonisin	407
2-[2-(\{19-amino-6-[(3,4-dicarboxybutanoyl)oxy]-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl\}oxy)-2-oxoethyl]butanedioic acid	0
2-[2-(\{19-amino-6-[(3,4-dicarboxybutanoyl)oxy]-18-hydroxy-5,9-dimethylicosan-7-yl\}oxy)-2-oxoethyl]butanedioic acid	0
Epi-Fumonisin B3	0
Epi-Fumonisin B4	0
Fumonisin A1	0
Fumonisin A2	0
Fumonisin B3	0
Iso-fumonisin B1	0
fumonisin B1	406
fumonisin B2	1
fumonisin B4	0
fumonisin B6	0
Path 2
Term	Annotations
CHEBI ontology	22210
subatomic particle	22202
composite particle	22202
hadron	22202
baryon	22202
nucleon	22202
atomic nucleus	22202
atom	22202
main group element atom	22136
p-block element atom	22136
carbon group element atom	21936
carbon atom	21861
organic molecular entity	21861
heteroorganic entity	21517
organochalcogen compound	21005
organooxygen compound	20846
carbon oxoacid	19634
carboxylic acid	19630
tricarboxylic acid	2597
tricarballylic acid	407
fumonisin	407
2-[2-(\{19-amino-6-[(3,4-dicarboxybutanoyl)oxy]-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl\}oxy)-2-oxoethyl]butanedioic acid	0
2-[2-(\{19-amino-6-[(3,4-dicarboxybutanoyl)oxy]-18-hydroxy-5,9-dimethylicosan-7-yl\}oxy)-2-oxoethyl]butanedioic acid	0
Epi-Fumonisin B3	0
Epi-Fumonisin B4	0
Fumonisin A1	0
Fumonisin A2	0
Fumonisin B3	0
Iso-fumonisin B1	0
fumonisin B1	406
fumonisin B2	1
fumonisin B4	0
fumonisin B6	0

paths to the root