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Gene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of SFTPD mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:3667 | 6480464 | Ethinyl Estradiol results in increased expression of SFTPD mRNA | CTD | PMID:17557909 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SFTPD mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SFTPD mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SFTPD mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:3667 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SFTPD mRNA | CTD | PMID:18990726 | acetylsalicylic acid | increases expression | ISO | RGD:735702 | 6480464 | Aspirin results in increased expression of SFTPD mRNA | CTD | PMID:15456535 | ammonium chloride | affects expression | ISO | RGD:3667 | 6480464 | Ammonium Chloride affects the expression of SFTPD mRNA | CTD | PMID:16483693 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of SFTPD mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of SFTPD mRNA | CTD | PMID:21964900 | benzo[a]pyrene | affects expression | EXP | | 6480464 | Benzo(a)pyrene affects the expression of SFTPD mRNA | CTD | PMID:22342234 | beryllium sulfate | increases expression | ISO | RGD:735702 | 6480464 | beryllium sulfate results in increased expression of SFTPD mRNA | CTD | PMID:16314022 | bis(2-chloroethyl) sulfide | decreases expression | ISO | RGD:3667 | 6480464 | Mustard Gas results in decreased expression of SFTPD protein | CTD | PMID:20659490 | bleomycin A2 | increases expression | ISO | RGD:3667 | 6480464 | Bleomycin results in increased expression of SFTPD mRNA; more ... | CTD | PMID:11880309 | cadmium dichloride | decreases methylation | ISO | RGD:3667 | 6480464 | Cadmium Chloride results in decreased methylation of SFTPD promoter | CTD | PMID:22457795 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SFTPD mRNA | CTD | PMID:20938992 | dioxygen | multiple interactions | ISO | RGD:3667 | 6480464 | [Paraquat co-treated with Oxygen] results in increased expression of SFTPD protein | CTD | PMID:11880309 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SFTPD mRNA | CTD | PMID:20938992 | furan | decreases methylation | ISO | RGD:3667 | 6480464 | furan results in decreased methylation of SFTPD gene | CTD | PMID:22079235 | hydrogen chloride | decreases expression | ISO | RGD:3667 | 6480464 | Hydrochloric Acid results in decreased expression of SFTPD protein | CTD | PMID:18573544 | hydrogen chloride | multiple interactions | ISO | RGD:3667 | 6480464 | S-methylisothiopseudouronium inhibits the reaction [Hydrochloric Acid results in decreased expression of SFTPD protein] | CTD | PMID:18573544 | hydrogen chloride | increases expression | ISO | RGD:3667 | 6480464 | Hydrochloric Acid results in increased expression of SFTPD protein | CTD | PMID:11880309 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SFTPD mRNA | CTD | PMID:20938992 | paraquat | decreases expression | ISO | RGD:735702 | 6480464 | Paraquat results in decreased expression of SFTPD protein | CTD | PMID:17503247 | paraquat | increases expression | ISO | RGD:3667 | 6480464 | Paraquat results in increased expression of SFTPD protein | CTD | PMID:17616020 | paraquat | decreases expression | ISO | RGD:3667 | 6480464 | Paraquat results in decreased expression of SFTPD protein | CTD | PMID:17616020 | paraquat | multiple interactions | ISO | RGD:3667 | 6480464 | [Paraquat co-treated with Oxygen] results in increased expression of SFTPD protein | CTD | PMID:11880309 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of SFTPD mRNA | CTD | PMID:17215068 | phorbol 13-acetate 12-myristate | multiple interactions | ISO | RGD:3667 | 6480464 | [Terbutaline co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SFTPD protein | CTD | PMID:9476903 | pirinixic acid | decreases expression | ISO | RGD:3667 | 6480464 | pirinixic acid results in decreased expression of SFTPD mRNA | CTD | PMID:19162173 | terbutaline | multiple interactions | ISO | RGD:3667 | 6480464 | [Terbutaline co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SFTPD protein | CTD | PMID:9476903 | toluene 2,4-diisocyanate | increases expression | EXP | | 6480464 | Toluene 2,4-Diisocyanate results in increased expression of SFTPD mRNA | CTD | PMID:11379042 | zearalenone | increases expression | ISO | RGD:3667 | 6480464 | Zearalenone results in increased expression of SFTPD mRNA | CTD | PMID:17557909 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Molecular Pathway Annotations| External Database Links | |
| KEGG Pathway | Phagosome |
| Pathway Interaction Database | FOXA1 transcription factor network (PID:200226) |
| Regulation of retinoblastoma protein (PID:200223) | |
Phenotype Annotations
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations
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| External Database Links | |
| KEGG Pathway | Phagosome |
| Pathway Interaction Database | FOXA1 transcription factor network (PID:200226) |
| Regulation of retinoblastoma protein (PID:200223) | |
Phenotype Annotations
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RGD automated import pipeline for gene-chemical interactions |
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RGD Disease Portals| Sftpd has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Sftpd (Mus musculus) |
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| SFTPD (Homo sapiens) |
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| Sftpd (Rattus norvegicus) |
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Position Markers| AI573415 |
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| UniSTS:237170 |
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| Sftpd |
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QTLs in Region (Mouse Genome Assembly Build 37)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_009160 | (Get FASTA) | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AAHY01113167 | (Get FASTA) | Search GEO for Microarray Profiles |
| AC124400 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF047741 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF047742 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF192134 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AI573415 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC003705 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC012896 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BG085186 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BY116790 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH466573 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CJ237327 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L40156 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_009160 | |||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | |||||||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||||||||
| Protein Acc Id: | NP_033186 | |||||||||||||||||||||||||
| Peptide Label: | precursor | |||||||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_033186 | (Get FASTA) |
| GenBank Protein | AAA92021 | (Get FASTA) |
| AAD31380 | (Get FASTA) | |
| AAF15277 | (Get FASTA) | |
| AAH03705 | (Get FASTA) | |
| EDL24923 | (Get FASTA) | |
| P50404 | (Get FASTA) |
Promoters| RGD ID: | 6825410 | ||||||||||
| Promoter ID: | MM_KWN:16277 | ||||||||||
| Type: | Non-CpG | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | Lung | ||||||||||
| Transcripts: | NM_009160 | ||||||||||
| Position: |
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSMUSG00000021795 | ENTREZGENE |
| Ensembl Protein | ENSMUSP00000076383 | ENTREZGENE |
| Ensembl Transcript | ENSMUST00000077136 | ENTREZGENE |
| Entrez Gene | 20390 | ENTREZGENE |
| Gene3D-CATH | C-type_lectin-like | UniProtKB/Swiss-Prot |
| G3DSA:1.20.5.360 | UniProtKB/Swiss-Prot | |
| Germonline | ENSMUSG00000021795 | |
| HomoloGene Group ID | 2272 | ENTREZGENE |
| InterPro | C-type_lectin | UniProtKB/Swiss-Prot |
| C-type_lectin-like | UniProtKB/Swiss-Prot | |
| C-type_lectin_CS | UniProtKB/Swiss-Prot | |
| C-type_lectin_fold | UniProtKB/Swiss-Prot | |
| Collagen | UniProtKB/Swiss-Prot | |
| Surfac_D-trimer | UniProtKB/Swiss-Prot | |
| KEGG Report | mmu:20390 | ENTREZGENE, UniProtKB/Swiss-Prot |
| MGD | MGI:109515 | ENTREZGENE |
| Pfam | Collagen | UniProtKB/Swiss-Prot |
| Lectin_C | UniProtKB/Swiss-Prot | |
| Surfac_D-trimer | UniProtKB/Swiss-Prot | |
| PROSITE | C_TYPE_LECTIN_1 | UniProtKB/Swiss-Prot |
| C_TYPE_LECTIN_2 | UniProtKB/Swiss-Prot | |
| SMART | CLECT | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | C-type_lectin_fold | UniProtKB/Swiss-Prot |
| UniGene | Mm.1321 | ENTREZGENE |
| UniProt | SFTPD_MOUSE | UniProtKB/Swiss-Prot |
| More on Sftpd | |
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Entrez Gene |
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Ensembl Gene |
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MGI Report |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 11287 |
| Created: | 2000-05-25 |
| Species: | Mus musculus |
| Last Modified: | 2013-03-19 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




