F10 (coagulation factor X) - Rat Genome Database

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Gene: F10 (coagulation factor X) Mus musculus
Analyze
Symbol: F10
Name: coagulation factor X
RGD ID: 62142
MGI Page MGI
Description: Predicted to enable phospholipid binding activity and serine-type endopeptidase activity. Predicted to be involved in positive regulation of TOR signaling. Predicted to act upstream of or within blood coagulation and proteolysis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including bone; lateral plate mesoderm; liver and biliary system; testis; and yolk sac. Human ortholog(s) of this gene implicated in breast cancer and factor X deficiency. Orthologous to human F10 (coagulation factor X).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AI1947; AI194738; Cf10; expressed sequence AI194738; fX; stuart factor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39813,087,308 - 13,106,676 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl813,087,308 - 13,106,676 (+)EnsemblGRCm39 Ensembl
GRCm38813,037,308 - 13,056,676 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl813,037,308 - 13,056,676 (+)EnsemblGRCm38mm10GRCm38
MGSCv37813,037,308 - 13,056,216 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36813,037,344 - 13,055,877 (+)NCBIMGSCv36mm8
Celera813,205,092 - 13,223,990 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map85.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-dinitrotoluene  (ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4-Chloro-ortho-phenylenediamine  (ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acenocoumarol  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (ISO)
aspalathin  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (ISO)
calcium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chlorogenic acid  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (EXP)
cyproconazole  (EXP)
dextran sulfate  (EXP)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
Difethialone  (ISO)
dioxygen  (ISO)
epoxiconazole  (EXP)
estriol  (ISO)
ethyl biscoumacetate  (ISO)
Ethyl icosapentate  (ISO)
ethylparaben  (ISO)
felbamate  (ISO)
fenthion  (EXP)
ferroheme b  (EXP)
flutamide  (ISO)
fondaparinux  (ISO)
fumonisin B1  (EXP)
furan  (ISO)
gabapentin  (ISO)
gentamycin  (ISO)
gestodene  (ISO)
heme b  (EXP)
heparin  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (ISO)
iron(III) citrate  (ISO)
kojic acid  (ISO)
lead(0)  (ISO)
lidocaine  (ISO)
mangiferin  (ISO)
menadione  (ISO)
menaquinone  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methapyrilene  (ISO)
methidathion  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
nimesulide  (ISO)
nitrofen  (ISO)
norethisterone  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phenprocoumon  (ISO)
phenytoin  (ISO)
pioglitazone  (EXP)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
rivaroxaban  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
Soman  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP)
tremolite asbestos  (EXP)
trichloroethene  (ISO)
trimellitic anhydride  (EXP)
trovafloxacin  (EXP)
valproic acid  (ISO)
varespladib  (ISO)
venom  (ISO)
vitamin E  (ISO)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Folate deficiency-induced hyperhomocysteinemia attenuates, and folic acid supplementation restores, the functional activities of rat coagulation factors XII, X, and II. Ebbesen LS and Ingerslev J, J Nutr. 2005 Aug;135(8):1836-40.
2. Cross Talk Pathways Between Coagulation and Inflammation. Foley JH and Conway EM, Circ Res. 2016 Apr 29;118(9):1392-408. doi: 10.1161/CIRCRESAHA.116.306853.
3. The inhibitors of the tissue factor:factor VII pathway. Golino P Thromb Res. 2002 May 1;106(3):V257-65.
4. Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury. Gralinski LE, etal., mBio. 2013 Aug 6;4(4). pii: mBio.00271-13. doi: 10.1128/mBio.00271-13.
5. Severe factor X deficiency in three unrelated Palestinian patients is caused by homozygosity for the mutation c302delG-correlation with thrombin generation and thromboelastometry. Livnat T, etal., Blood Coagul Fibrinolysis. 2011 Dec;22(8):673-9. doi: 10.1097/MBC.0b013e32834ad785.
6. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. MGD IEA MGD IEA
9. Effect of dienogest on bleeding time, coagulation, fibrinolysis, and platelet aggregation in female rats. Nobukata H, etal., Toxicol Lett. 1999 Jan 11;104(1-2):93-101.
10. Blood coagulation. Norris LA, Best Pract Res Clin Obstet Gynaecol. 2003 Jun;17(3):369-83.
11. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
12. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
13. Early embryonic expression of murine coagulation system components. Ong K, etal., Thromb Haemost 2000 Dec;84(6):1023-30.
14. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
15. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
16. Molecular characterization of human factor XSan Antonio. Reddy SV, etal., Blood. 1989 Oct;74(5):1486-90.
17. Mouse MP Annotation Import Pipeline RGD automated import pipeline
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. Tissue factor and factor v involvement in rat peritoneal fibrosis. Saito H, etal., Perit Dial Int. 2009 May-Jun;29(3):340-51.
21. How it all starts: Initiation of the clotting cascade. Smith SA, etal., Crit Rev Biochem Mol Biol. 2015;50(4):326-36. doi: 10.3109/10409238.2015.1050550. Epub 2015 May 28.
22. Coagulation and fibrinolysis abnormalities in familial amyloid polyneuropathy. Takahashi R, etal., Amyloid. 2012 Sep;19(3):129-32. doi: 10.3109/13506129.2012.691918. Epub 2012 May 25.
23. Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study. Tinholt M, etal., BMC Cancer. 2014 Nov 19;14:845. doi: 10.1186/1471-2407-14-845.
24. Intracellular proteolytic processing of the two-chain vitamin K-dependent coagulation factor X. Wallin R, etal., Thromb Res. 1994 Mar 15;73(6):395-403.
Additional References at PubMed
PMID:7613031   PMID:9684791   PMID:9759642   PMID:9783672   PMID:10349636   PMID:10739370   PMID:10823271   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11841337   PMID:12161341  
PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16944957   PMID:17082493   PMID:18036190   PMID:18267072   PMID:18287559   PMID:19339215   PMID:19546589   PMID:19652365  
PMID:20487527   PMID:21252090   PMID:21386911   PMID:21596747   PMID:21628879   PMID:21873635   PMID:21885613   PMID:23049768   PMID:23472758   PMID:23872307   PMID:24194600   PMID:24533719  
PMID:25007770   PMID:26608330   PMID:27283743   PMID:27626380   PMID:28213380   PMID:28283478   PMID:28378742   PMID:29321368   PMID:29930175   PMID:30870413   PMID:31461896   PMID:31541031  
PMID:32325033   PMID:35055169   PMID:38096370  


Genomics

Comparative Map Data
F10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39813,087,308 - 13,106,676 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl813,087,308 - 13,106,676 (+)EnsemblGRCm39 Ensembl
GRCm38813,037,308 - 13,056,676 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl813,037,308 - 13,056,676 (+)EnsemblGRCm38mm10GRCm38
MGSCv37813,037,308 - 13,056,216 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36813,037,344 - 13,055,877 (+)NCBIMGSCv36mm8
Celera813,205,092 - 13,223,990 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map85.73NCBI
F10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813113,122,799 - 113,149,529 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13113,122,799 - 113,149,529 (+)EnsemblGRCh38hg38GRCh38
GRCh3713113,777,113 - 113,803,843 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613112,825,114 - 112,851,844 (+)NCBINCBI36Build 36hg18NCBI36
Build 3413112,825,145 - 112,851,842NCBI
Celera1394,603,103 - 94,629,507 (+)NCBICelera
Cytogenetic Map13q34NCBI
HuRef1394,215,823 - 94,242,228 (+)NCBIHuRef
CHM1_113113,745,235 - 113,771,639 (+)NCBICHM1_1
T2T-CHM13v2.013112,374,457 - 112,401,188 (+)NCBIT2T-CHM13v2.0
F10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81683,170,973 - 83,190,280 (-)NCBIGRCr8
mRatBN7.21676,468,834 - 76,488,141 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1676,468,838 - 76,488,141 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1681,749,382 - 81,768,689 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01685,201,959 - 85,221,266 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01680,451,223 - 80,470,556 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01681,803,169 - 81,822,476 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1681,803,110 - 81,822,716 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01681,288,536 - 81,307,842 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41681,327,237 - 81,346,544 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11681,327,502 - 81,346,809 (-)NCBI
Celera1674,274,866 - 74,294,173 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
F10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955404666,165 - 682,538 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955404666,142 - 682,598 (-)NCBIChiLan1.0ChiLan1.0
F10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214114,625,296 - 114,651,858 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113113,310,076 - 113,337,459 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01394,263,202 - 94,289,612 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113113,332,124 - 113,358,660 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13113,332,124 - 113,358,660 (+)Ensemblpanpan1.1panPan2
F10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12260,585,563 - 60,597,027 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2260,571,822 - 60,597,024 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2260,297,960 - 60,309,413 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02261,211,249 - 61,222,710 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2261,211,250 - 61,222,699 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12260,709,507 - 60,721,052 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02260,711,813 - 60,723,235 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02260,742,888 - 60,754,688 (+)NCBIUU_Cfam_GSD_1.0
F10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945195,449,719 - 195,476,829 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936472475,333 - 502,377 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936472475,851 - 502,341 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
F10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1178,521,598 - 78,538,258 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11178,521,760 - 78,538,256 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21186,197,298 - 86,215,095 (-)NCBISscrofa10.2Sscrofa10.2susScr3
F10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1391,125,097 - 91,154,000 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl391,124,766 - 91,157,376 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604648,141,434 - 48,190,001 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
F10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624793762,330 - 778,282 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624793762,306 - 777,511 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in F10
577 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1014
Count of miRNA genes:500
Interacting mature miRNAs:594
Transcripts:ENSMUST00000033821, ENSMUST00000063820, ENSMUST00000123768, ENSMUST00000128418, ENSMUST00000152034
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13432571Scvg1_msubcutaneous vessel growth QTL 1 (mouse)8124751082Mouse
11533914Mts5_mmammary tumor susceptibility 5 (mouse)8130447432Mouse
4140978Nilac5_mnicotine induced locomotor activity 5 (mouse)Not determined8131773288Mouse
27226756Femd2_mfemur midshaft diameter 2, 5 week (mouse)8495000035067154Mouse
1357525Pnhdlc3_mplasma non-HDL cholesterol 3 (mouse)Not determined8721249923753815Mouse
1301532Scc8_mcolon tumor susceptibility 8 (mouse)Not determined8721249935110107Mouse
1300906Ap8q_malcohol preference 8 QTL (mouse)Not determined8798418941984342Mouse
10412209Cypr7_mcytokine production 7 (mouse)Not determined8810320142103372Mouse
1301929Eae24_msusceptibility to experimental allergic encephalomyelitis 24 (mouse)Not determined8810320142103372Mouse
1301128Sluc20_msusceptibility to lung cancer 20 (mouse)Not determined8810320142103372Mouse
14697703Stsl1_mSalmonella typhimurium susceptibility locus 1 (mouse)81135000017050016Mouse

Markers in Region
AI132620  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38813,035,433 - 13,035,536UniSTSGRCm38
MGSCv37813,035,433 - 13,035,536UniSTSGRCm37
Celera813,203,217 - 13,203,320UniSTS
Cytogenetic Map8A1.1UniSTS
Whitehead/MRC_RH8141.97UniSTS
Whitehead/MRC_RH8139.9UniSTS
AI194738  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38813,056,496 - 13,056,602UniSTSGRCm38
MGSCv37813,056,496 - 13,056,602UniSTSGRCm37
Celera813,224,268 - 13,224,374UniSTS
Cytogenetic Map8A1.1UniSTS
Whitehead/MRC_RH8143.08UniSTS
F7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38813,035,572 - 13,035,745UniSTSGRCm38
MGSCv37813,035,572 - 13,035,745UniSTSGRCm37
Celera813,203,356 - 13,203,529UniSTS
Cytogenetic Map8A1.1UniSTS
cM Map87.0UniSTS
F10  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38813,055,413 - 13,055,668UniSTSGRCm38
MGSCv37813,055,413 - 13,055,668UniSTSGRCm37
Celera813,223,187 - 13,223,442UniSTS
Cytogenetic Map8A1.1UniSTS
cM Map87.0UniSTS
F7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38813,035,432 - 13,035,736UniSTSGRCm38
MGSCv37813,035,432 - 13,035,736UniSTSGRCm37
Celera813,203,216 - 13,203,520UniSTS
Cytogenetic Map8A1.1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001242368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC127308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF085811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF087644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF211347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI194738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI506285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ222677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC050219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000033821   ⟹   ENSMUSP00000033821
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl813,087,322 - 13,105,900 (+)Ensembl
GRCm38.p6 Ensembl813,037,322 - 13,055,900 (+)Ensembl
RefSeq Acc Id: ENSMUST00000063820   ⟹   ENSMUSP00000068389
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl813,087,308 - 13,106,676 (+)Ensembl
GRCm38.p6 Ensembl813,037,308 - 13,056,676 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123768   ⟹   ENSMUSP00000116984
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl813,087,587 - 13,096,147 (+)Ensembl
GRCm38.p6 Ensembl813,037,587 - 13,046,147 (+)Ensembl
RefSeq Acc Id: ENSMUST00000128418   ⟹   ENSMUSP00000121830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl813,087,838 - 13,105,835 (+)Ensembl
GRCm38.p6 Ensembl813,037,838 - 13,055,835 (+)Ensembl
RefSeq Acc Id: ENSMUST00000152034   ⟹   ENSMUSP00000117312
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl813,087,838 - 13,105,895 (+)Ensembl
GRCm38.p6 Ensembl813,037,838 - 13,055,895 (+)Ensembl
RefSeq Acc Id: NM_001242368   ⟹   NP_001229297
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39813,087,308 - 13,106,676 (+)NCBI
GRCm38813,037,308 - 13,056,676 (+)ENTREZGENE
Celera813,205,092 - 13,224,448 (+)ENTREZGENE
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_007972   ⟹   NP_031998
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39813,087,308 - 13,106,676 (+)NCBI
GRCm38813,037,308 - 13,056,676 (+)ENTREZGENE
MGSCv37813,037,308 - 13,056,216 (+)RGD
Celera813,205,092 - 13,224,448 (+)ENTREZGENE
cM Map8 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_031998   ⟸   NM_007972
- Peptide Label: isoform 2 preproprotein
- UniProtKB: O54740 (UniProtKB/Swiss-Prot),   Q99L32 (UniProtKB/Swiss-Prot),   O88947 (UniProtKB/Swiss-Prot),   Q3TBR2 (UniProtKB/TrEMBL),   Q4FJS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001229297   ⟸   NM_001242368
- Peptide Label: isoform 1 precursor
- UniProtKB: Q3U3V1 (UniProtKB/TrEMBL),   Q3TDB9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000117312   ⟸   ENSMUST00000152034
RefSeq Acc Id: ENSMUSP00000033821   ⟸   ENSMUST00000033821
RefSeq Acc Id: ENSMUSP00000121830   ⟸   ENSMUST00000128418
RefSeq Acc Id: ENSMUSP00000116984   ⟸   ENSMUST00000123768
RefSeq Acc Id: ENSMUSP00000068389   ⟸   ENSMUST00000063820
Protein Domains
EGF-like   Gla   Peptidase S1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88947-F1-model_v2 AlphaFold O88947 1-481 view protein structure

Promoters
RGD ID:6843109
Promoter ID:MM_KWN:53679
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Liver,   Lung,   Spleen
Transcripts:OTTMUST00000048844,   OTTMUST00000048846,   OTTMUST00000048847,   OTTMUST00000049051,   OTTMUST00000081484,   UC009KWT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36813,036,566 - 13,037,692 (+)MPROMDB
RGD ID:8666471
Promoter ID:EPDNEW_M11267
Type:initiation region
Name:F10_1
Description:Mus musculus coagulation factor X , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11268  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38813,037,378 - 13,037,438EPDNEW
RGD ID:8666473
Promoter ID:EPDNEW_M11268
Type:initiation region
Name:F10_2
Description:Mus musculus coagulation factor X , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11267  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38813,037,817 - 13,037,877EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:103107 AgrOrtholog
Ensembl Genes ENSMUSG00000031444 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000033821 ENTREZGENE
  ENSMUST00000033821.11 UniProtKB/TrEMBL
  ENSMUST00000063820 ENTREZGENE
  ENSMUST00000063820.12 UniProtKB/Swiss-Prot
  ENSMUST00000123768.8 UniProtKB/TrEMBL
  ENSMUST00000128418.8 UniProtKB/TrEMBL
  ENSMUST00000152034.2 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.740.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Coagulation_fac-like_Gla_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLA-like_dom_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLA_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_S1A_FX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14058 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:103107 ENTREZGENE
NCBI Gene 14058 ENTREZGENE
PANTHER COAGULATION FACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  COAGULATION FACTOR X UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FXa_inhibition UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gla UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Trypsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB F10 RGD
PhenoGen F10 PhenoGen
PIRSF Factor_X UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGFBLOOD UniProtKB/TrEMBL
  GLABLOOD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLA_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57630 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z215_MOUSE UniProtKB/TrEMBL
  D3Z521_MOUSE UniProtKB/TrEMBL
  D3Z7R3_MOUSE UniProtKB/TrEMBL
  FA10_MOUSE UniProtKB/Swiss-Prot
  O54740 ENTREZGENE
  O88947 ENTREZGENE
  Q3TBR2 ENTREZGENE, UniProtKB/TrEMBL
  Q3TDB9 ENTREZGENE, UniProtKB/TrEMBL
  Q3U3V1 ENTREZGENE, UniProtKB/TrEMBL
  Q4FJS7 ENTREZGENE, UniProtKB/TrEMBL
  Q80Y26_MOUSE UniProtKB/TrEMBL
  Q99L32 ENTREZGENE
UniProt Secondary O54740 UniProtKB/Swiss-Prot
  Q99L32 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-18 F10  coagulation factor X  AI194738  expressed sequence AI194738  Data merged from RGD:1610566 737654 PROVISIONAL