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65 records found for search term F2r
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
2586F2rcoagulation factor II (thrombin) receptorENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN establishment of synaptic specificity at neuromuscular junction; G protein-coupled receptor signaling pathway; negative r22860406628620579Rat396symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
10556F2rcoagulation factor II thrombin receptorEnables G protein-coupled receptor activity; G-protein alpha-subunit binding activity; and G-protein beta-subunit binding activity. Involved in several processes, including modulation of chemical synaptic transmission; negative regulation of renin secretion into blood stream; and positive regulation139573828895754974Mouse462symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
735960F2Rcoagulation factor II thrombin receptorCoagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multi57671612676735770Human357symbol , COSMIC , description , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
8785220F2rcoagulation factor II thrombin receptorENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN cell-cell junction maintenance (ortholog); connective tissue replacement involved in inflammatory response wound healing NW_0049554252414490524164498Chinchilla84symbolgene, protein-coding, MODEL [RefSeq]
11673386F2Rcoagulation factor II thrombin receptorENCODES a protein that exhibits G protein-coupled receptor activity (inferred); G-protein alpha-subunit binding (inferred); G-protein beta-subunit binding (inferred); INVOLVED IN blood coagulation (inferred); cell-cell junction maintenance (inferred); connective tissue replacement involved in inflam53846252138478882Bonobo72symbol , old_gene_name , old_gene_symbolgene, protein-coding, MODEL [RefSeq]
12078373F2Rcoagulation factor II thrombin receptorENCODES a protein that exhibits G protein-coupled receptor activity (inferred); G-protein alpha-subunit binding (inferred); G-protein beta-subunit binding (inferred); INVOLVED IN establishment of synaptic specificity at neuromuscular junction (ortholog); G protein-coupled receptor signaling pathway 32987015929889837Dog99symbolgene, protein-coding, MODEL [RefSeq]
12639567F2rcoagulation factor II thrombin receptorENCODES a protein that exhibits G protein-coupled receptor activity (inferred); G-protein alpha-subunit binding (inferred); G-protein beta-subunit binding (inferred); INVOLVED IN establishment of synaptic specificity at neuromuscular junction (ortholog); G protein-coupled receptor signaling pathway NW_004936549226508247024Squirrel101symbolgene, protein-coding, MODEL [RefSeq]
14143831F2Rcoagulation factor II thrombin receptorENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN connective tissue replacement involved in inflammatory response wound healing (ortholog); establishment of synaptic speciPig141symbolgene, protein-coding, PROVISIONAL [RefSeq]
18752771F2Rcoagulation factor II thrombin receptorENCODES a protein that exhibits G protein-coupled receptor activity (inferred); G-protein alpha-subunit binding (inferred); G-protein beta-subunit binding (inferred); INVOLVED IN establishment of synaptic specificity at neuromuscular junction (ortholog); G protein-coupled receptor signaling pathway Green Monkey101symbolgene, protein-coding, MODEL [RefSeq]
18913546F2rcoagulation factor II thrombin receptorENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell-cell junction maintenance (ortholog); connective tissue replacement involved in inflammatory response wound healing (orthologNaked Mole-Rat104symbolgene, protein-coding, MODEL [RefSeq]
155245458f2rTropical Clawed Frogsymbolgene, null
626077132F2rcoagulation factor II thrombin receptorENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN cell-cell junction maintenance (ortholog); connective tissue replacement involved in inflammatory response wound healing Black Rat84symbolgene, protein-coding, MODEL [RefSeq]
155235176f2r.LAfrican Clawed Frogsymbolgene, null
155257891f2r.SAfrican Clawed Frogsymbolgene, null
13799351F2rem1Mcwicoagulation factor II (thrombin) receptor; CRISPR/Cas9 induced mutant 1, McwiCRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 1 of F2r gene in the T2DN/Mcwi embryos.Ratsymbol , descriptiongene, allele
620866F2rl1F2R like trypsin receptor 1ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN positive regulation of glomerular filtration; vasodilation; cell-cell junction maintenance (ortholog); PARTICIPATES IN pr22850700328519954Rat368symbol , PhenoGen , namegene, protein-coding, PROVISIONAL [RefSeq]
733704F2RL1F2R like trypsin receptor 1This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop dom57681903076835315Human302symbol , COSMIC , name , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1553673F2rl1F2R like trypsin receptor 1Enables G-protein alpha-subunit binding activity; G-protein beta-subunit binding activity; and proteinase-activated receptor activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of intracellular signal transduction; and regulation of prot139564822695661748Mouse386symbol , PhenoGen , name , descriptiongene, protein-coding, VALIDATED [RefSeq]
8951129F2rl1F2R like trypsin receptor 1ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN cell-cell junction maintenance (ortholog); defense response to virus (ortholog); establishment of endothelial barrier (orNW_0049554252405090124054039Chinchilla88symbol , namegene, protein-coding, MODEL [RefSeq]
12210549F2RL1F2R like trypsin receptor 1ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN defense response to virus (ortholog); leukocyte proliferation (ortholog); mature conventional dendritic cell differentiat32980111929810006Dog116symbol , namegene, protein-coding, PROVISIONAL [RefSeq]
12555200F2rl1F2R like trypsin receptor 1ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); G-protein alpha-subunit binding (inferred); G-protein beta-subunit binding (inferred); INVOLVED IN positive regulation of glomerular filtration (ortholog); positive regulation of GTPase activity (ortholog); positive reguNW_004936549142281153575Squirrel93symbol , namegene, protein-coding, MODEL [RefSeq]
13878644F2RL1F2R like trypsin receptor 1ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN positive regulation of vasoconstriction; defense response to virus (ortholog); leukocyte proliferation (ortholog); PARTICPig113symbol , namegene, protein-coding, MODEL [RefSeq]
18670982F2RL1F2R like trypsin receptor 1ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); G-protein alpha-subunit binding (inferred); G-protein beta-subunit binding (inferred); INVOLVED IN positive regulation of glomerular filtration (ortholog); positive regulation of GTPase activity (ortholog); positive reguGreen Monkey93symbol , namegene, protein-coding, MODEL [RefSeq]
18919338F2rl1F2R like trypsin receptor 1ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN cell-cell junction maintenance (ortholog); defense response to virus (ortholog); establishment of endothelial barrier (orNaked Mole-Rat91symbol , namegene, protein-coding, MODEL [RefSeq]
39131446F2RL1F2R like trypsin receptor 1Chinchillasymbol , namegene, protein-coding
329877732F2RL1F2R like trypsin receptor 1ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); G-protein alpha-subunit binding (inferred); G-protein beta-subunit binding (inferred); INVOLVED IN positive regulation of glomerular filtration (ortholog); positive regulation of GTPase activity (ortholog); positive reguBonobo94symbol , namegene, protein-coding, MODEL [RefSeq]
625890966F2rl1F2R like trypsin receptor 1ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN cell-cell junction maintenance (ortholog); defense response to virus (ortholog); establishment of endothelial barrier (orBlack Rat88symbol , namegene, protein-coding, MODEL [RefSeq]
16553186AC025188.1novel transcript, antisense to F2RHumannamegene, lncrna
620872F2rl3F2R like thrombin or trypsin receptor 3ENCODES a protein that exhibits protease binding (ortholog); INVOLVED IN platelet activation (ortholog); platelet aggregation (ortholog); positive regulation of release of sequestered calcium ion into cytosol (ortholog); PARTICIPATES IN protease mediated signaling via protease-activated receptor 4; 161715151617153509Rat77symbol , old_gene_name , PhenoGen , namegene, protein-coding, PROVISIONAL [RefSeq]
731394F2rl3F2R like thrombin or trypsin receptor 3This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays 87348828773490526Mouse83symbol , PhenoGen , namegene, protein-coding, REVIEWED [RefSeq]
1351365F2RL3F2R like thrombin or trypsin receptor 3This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays 191688899916892606Human86symbol , old_gene_name , COSMIC , name , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8715843F2rl3F2R like thrombin or trypsin receptor 3ENCODES a protein that exhibits protease binding (ortholog); INVOLVED IN platelet activation (ortholog); platelet aggregation (ortholog); positive regulation of release of sequestered calcium ion into cytosol (ortholog); PARTICIPATES IN protease mediated signaling via protease-activated receptor 4; NW_00495552410454931047924Chinchilla9symbol , old_gene_name , namegene, protein-coding, MODEL [RefSeq]
11808944F2RL3F2R like thrombin or trypsin receptor 3ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); protease binding (inferred); thrombin-activated receptor activity (inferred); INVOLVED IN platelet aggregation (ortholog); PARTICIPATES IN protease mediated signaling via protease-activated receptor 4; ASSOCIATED WITH Ch191637557216379587Bonobo26symbol , old_gene_name , namegene, protein-coding, MODEL [RefSeq]
12316766F2RL3F2R like thrombin or trypsin receptor 3ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); protease binding (inferred); thrombin-activated receptor activity (inferred); INVOLVED IN platelet aggregation (ortholog); PARTICIPATES IN protease mediated signaling via protease-activated receptor 4; ASSOCIATED WITH Ch204573858745740564Dog25symbol , old_gene_name , namegene, protein-coding, MODEL [RefSeq]
14041628F2RL3F2R like thrombin or trypsin receptor 3ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); protease binding (inferred); thrombin-activated receptor activity (inferred); INVOLVED IN platelet aggregation (ortholog); PARTICIPATES IN protease mediated signaling via protease-activated receptor 4; ASSOCIATED WITH ChPig25symbol , old_gene_name , namegene, protein-coding, MODEL [RefSeq]
18622580F2RL3F2R like thrombin or trypsin receptor 3ENCODES a protein that exhibits protease binding (ortholog); INVOLVED IN platelet activation (ortholog); platelet aggregation (ortholog); positive regulation of release of sequestered calcium ion into cytosol (ortholog); PARTICIPATES IN protease mediated signaling via protease-activated receptor 4; Green Monkey9symbol , old_gene_name , namegene, protein-coding, MODEL [RefSeq]
18934192F2rl3F2R like thrombin or trypsin receptor 3ENCODES a protein that exhibits protease binding (ortholog); INVOLVED IN platelet aggregation (ortholog); positive regulation of release of sequestered calcium ion into cytosol (ortholog); PARTICIPATES IN protease mediated signaling via protease-activated receptor 4; ASSOCIATED WITH Chemical and DruNaked Mole-Rat24symbol , old_gene_name , namegene, protein-coding, MODEL [RefSeq]
20866152F2RL3F2R like thrombin or trypsin receptor 3ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); protease binding (inferred); thrombin-activated receptor activity (inferred); INVOLVED IN blood coagulation (inferred); G protein-coupled receptor signaling pathway (inferred); hemostasis (inferred); FOUND IN membrane (iGreen Monkey21symbol , namegene, protein-coding
626018256F2rl3F2R like thrombin or trypsin receptor 3ENCODES a protein that exhibits protease binding (ortholog); INVOLVED IN platelet activation (ortholog); platelet aggregation (ortholog); positive regulation of release of sequestered calcium ion into cytosol (ortholog); PARTICIPATES IN protease mediated signaling via protease-activated receptor 4; Black Rat9symbol , namegene, protein-coding, MODEL [RefSeq]
2312709NCRUPARnon-protein coding RNA, upstream of F2R/PAR1This non-coding RNA gene has been reported to have a positive regulatory affect during embryogenesis on the adjacent coagulation factor II (thrombin) receptor gene by Madamanchi et. al (PMID:12084570). [provided by RefSeq, Aug 2012]57671240376712888Human5namegene, ncrna, REVIEWED [RefSeq]
284575520f2rl1Tropical Clawed Frogsymbolgene, null
620871F2rl2coagulation factor II (thrombin) receptor-like 2ENCODES a protein that exhibits proteinase-activated receptor activity (ortholog); receptor ligand activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN insulin signaling pathway; protease mediated signaling via protease-activated receptor 3; FOUND22870676628711808Rat130symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
736561F2rl2coagulation factor II thrombin receptor like 2Enables proteinase-activated receptor activity and receptor ligand activity. Involved in G protein-coupled receptor signaling pathway; ligand-gated ion channel signaling pathway; and positive regulation of insulin secretion. Located in apical plasma membrane. Is expressed in several structures, incl139583342895839276Mouse130symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1348825F2RL2coagulation factor II thrombin receptor like 2This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family57661548276623403Human133symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8877455F2rl2coagulation factor II thrombin receptor like 2ENCODES a protein that exhibits proteinase-activated receptor activity (ortholog); receptor ligand activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN insulin signaling pathway; protease mediated signaling via protease-activated receptor 3; FOUNDNW_0049554252424633324254887Chinchilla10symbolgene, protein-coding, MODEL [RefSeq]
12043880F2RL2coagulation factor II thrombin receptor like 2ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); proteinase-activated receptor activity (inferred); receptor ligand activity (inferred); INVOLVED IN blood coagulation (inferred); G protein-coupled receptor signaling pathway (inferred); phospholipase C-activating G prot53868037238688509Bonobo24symbolgene, protein-coding, MODEL [RefSeq]
12420576F2RL2coagulation factor II thrombin receptor like 2ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); proteinase-activated receptor activity (inferred); receptor ligand activity (inferred); INVOLVED IN blood coagulation (inferred); G protein-coupled receptor signaling pathway (inferred); signal transduction (inferred); P32996727829974316Dog22symbolgene, protein-coding, MODEL [RefSeq]
12610287F2rl2coagulation factor II thrombin receptor like 2ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); proteinase-activated receptor activity (inferred); receptor ligand activity (inferred); INVOLVED IN blood coagulation (inferred); G protein-coupled receptor signaling pathway (inferred); phospholipase C-activating G protNW_004936549336871342992Squirrel23symbolgene, protein-coding, MODEL [RefSeq]
13971865F2RL2coagulation factor II thrombin receptor like 2ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); proteinase-activated receptor activity (inferred); receptor ligand activity (inferred); INVOLVED IN blood coagulation (inferred); G protein-coupled receptor signaling pathway (inferred); signal transduction (inferred); PPig20symbolgene, protein-coding, MODEL [RefSeq]
18459082F2RL2coagulation factor II thrombin receptor like 2ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); proteinase-activated receptor activity (inferred); receptor ligand activity (inferred); INVOLVED IN blood coagulation (inferred); G protein-coupled receptor signaling pathway (inferred); phospholipase C-activating G protGreen Monkey23symbolgene, protein-coding, MODEL [RefSeq]
18932812F2rl2coagulation factor II thrombin receptor like 2ENCODES a protein that exhibits proteinase-activated receptor activity (ortholog); receptor ligand activity (ortholog); INVOLVED IN blood coagulation (inferred); G protein-coupled receptor signaling pathway (inferred); phospholipase C-activating G protein-coupled receptor signaling pathway (inferredNaked Mole-Rat22symbolgene, protein-coding, MODEL [RefSeq]
155236637f2rl2Tropical Clawed Frogsymbolgene, null
625983931F2rl2coagulation factor II thrombin receptor like 2ENCODES a protein that exhibits proteinase-activated receptor activity (ortholog); receptor ligand activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN insulin signaling pathway; protease mediated signaling via protease-activated receptor 3; FOUNDBlack Rat10symbolgene, protein-coding, MODEL [RefSeq]
155250391f2rl3Tropical Clawed Frogsymbolgene, null
288057015f2rl1.LAfrican Clawed Frogsymbolgene, null
285025340f2rl1.SAfrican Clawed Frogsymbolgene, null
155237002f2rl2.LAfrican Clawed Frogsymbolgene, null
155236638f2rl2.SAfrican Clawed Frogsymbolgene, null
155249552f2rl3.LAfrican Clawed Frogsymbolgene, null
735620F9coagulation factor IXThis gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide boX139530739139563459Human446UniProt , old_protein_id , UniProt Secondarygene, protein-coding, REVIEWED [RefSeq]
1349444HLA-Amajor histocompatibility complex, class I, AHLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived62994253229945870Human300UniProtgene, protein-coding, REVIEWED [RefSeq]
1352836HLA-Bmajor histocompatibility complex, class I, BHLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived63135387531357179Human573UniProtgene, protein-coding, REVIEWED [RefSeq]
1353906HLA-DQB1major histocompatibility complex, class II, DQ beta 1HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II mole63265946732666657Human709UniProtgene, protein-coding, REVIEWED [RefSeq]
1349823HLA-DRB1major histocompatibility complex, class II, DR beta 1HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molec63257877532589848Human861UniProtgene, protein-coding, REVIEWED [RefSeq]
736735RHDRh blood group D antigenThe Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD p12527248625330445Human92UniProtgene, protein-coding, REVIEWED [RefSeq]