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Gene: F9 (coagulation factor IX) Homo sapiens
Symbol: F9
Name: coagulation factor IX
Description: Exhibits calcium ion binding activity and endopeptidase activity. Involved in blood coagulation and zymogen activation. Localizes to the extracellular space. Implicated in hemophilia B and thrombophilia. Biomarker of type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Christmas factor; coagulation factor 9; coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B); F9 p22; factor 9; factor IX F9; FIX; FIX F9; HEMB; MGC129641; MGC129642; P19; plasma thromboplastic component; plasma thromboplastin component; PTC; serine protease; THPH8
Mus musculus (house mouse) : F9 (coagulation factor IX)  MGI  Alliance
Rattus norvegicus (Norway rat) : F9 (coagulation factor IX)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F9 (coagulation factor IX)
Pan paniscus (bonobo/pygmy chimpanzee) : F9 (coagulation factor IX)
Canis lupus familiaris (dog) : F9 (coagulation factor IX)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F9 (coagulation factor IX)
Sus scrofa (pig) : F9 (coagulation factor IX)
Chlorocebus sabaeus (African green monkey) : F9 (coagulation factor IX)
Heterocephalus glaber (naked mole-rat) : F9 (coagulation factor IX)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX139,530,739 - 139,563,459 (+)Ensembl
GRCh38 EnsemblX139,530,758 - 139,563,458 (+)Ensembl
GRCh38X139,530,720 - 139,563,459 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X138,612,889 - 138,645,617 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X138,440,561 - 138,473,283 (+)NCBINCBI36hg18NCBI36
Build 34X138,338,414 - 138,371,137NCBI
CeleraX138,980,334 - 139,013,056 (+)NCBI
Cytogenetic MapXq27.1NCBI
HuRefX127,880,671 - 127,913,025 (+)NCBIHuRef
CHM1_1X138,523,783 - 138,556,510 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on F9
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735620
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.