Rf6 QTL Report (Rattus norvegicus) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: Rf6 (Renal function QTL 6) Rattus norvegicus

Symbol: Rf6
Name: Renal function QTL 6
RGD ID: 1300170
Previously known as: Specialized Center of Research QTL 69; SCOR69
Trait: renal blood flow trait   (VT:2000006)    
Measurement Type: absolute change in renal blood flow rate   (CMO:0001168)    
LOD Score: 3.14
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr811 - 28,483,164RGD_MAPPER_PIPELINE
mRatBN7.214,162,807 - 11,481,482RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.013,839,159 - 11,314,658RGD_MAPPER_PIPELINERnor6.0
Rnor_5.015,511,572 - 12,920,275RGDRnor5.0
RGSC_v3.414,404,877 - 11,860,328RGDRGSC3.4
RGSC_v3.114,404,878 - 11,860,218RGD
Cross Type: Not Available
Strains Crossed: BN/SsNHsd SS/JrHsdMcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
kidney disease  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
BN/SsNHsd  (IEA)
SS/JrHsdMcwi  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats. Moreno C, etal., Physiol Genomics 2003 Nov 11;15(3):243-57. Epub 2003 Oct 07.
Related QTLs

Related QTL Description Reference
Rf8 interacts with RGD:727992


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1560633Rpl27al2ribosomal protein L27A like 2141709944174755Rat
708517Stxbp5syntaxin binding protein 5141824894335290Rat
41123607LOC120098776uncharacterized LOC120098776142708544275128Rat
41059876LOC120100355small nucleolar RNA SNORA36 family142761314276261Rat
41114960Rpl7a-ps6ribosomal protein L7a, pseudogene 6143730764376648Rat
2316474Vom1r-ps1vomeronasal 1 receptor pseudogene 1146918754692748Rat
1564259Adgbandroglobin147536214896268Rat
7621680Eif4a1-ps5eukaryotic translation initiation factor 4A1, pseudogene 5147603764761823Rat
1559997Rab32RAB32, member RAS oncogene family149461934961003Rat
41047298LOC120100440small nucleolar RNA SNORA17150382355038365Rat
2742Grm1glutamate metabotropic receptor 1150582855453170Rat
1559475Dctn3l1dynactin 3-like 1155268315527628Rat
1310342ShprhSNF2 histone linker PHD RING helicase155288275602537Rat
7501317LOC102547024uncharacterized LOC102547024156121185621767Rat
1359367Fbxo30F-box protein 30156553415671558Rat
41167813Snora70jsmall nucleolar RNA, H/ACA box 70J157208035720940Rat
71047Epm2aEPM2A glucan phosphatase, laforin157271115845338Rat
41221841LOC120100424small nucleolar RNA SNORA17160057856005914Rat
7654508LOC102547285uncharacterized LOC102547285161154836129261Rat
41284286LOC120098779uncharacterized LOC120098779162008346241934Rat
41091704LOC120100351small nucleolar RNA SNORA31163083546308480Rat
1586118Slc25a53-ps1solute carrier family 25, member 53, pseudogene 1163305346331811Rat
1593147Ldha-ps21lactate dehydrogenase A, pseudogene 21166243716625798Rat
1586117Plxnb2-ps1plexin B2, pseudogene 1166635766665946Rat
3947Utrnutrophin167208547224313Rat
11401898Trnal-uaa1transfer RNA leucine (anticodon UAA) 1172719807272062Rat
1304744Stx11syntaxin 11172934277320060Rat
41018580LOC120098780uncharacterized LOC120098780173338417336406Rat
40987896LOC120098781uncharacterized LOC120098781173467257349946Rat
40957540LOC120100405small nucleolar RNA SNORA48173470757347218Rat
1586993Sf3b5splicing factor 3b, subunit 5173570407357752Rat
1586116Ftl1-ps4ferritin light chain 1, pseudogene 4174167757429173Rat
3014Plagl1PLAG1 like zinc finger 1174772957517229Rat
2319701Zc2hc1bzinc finger, C2HC-type containing 1B175372917565054Rat
1311264Ltv1LTV1 ribosome biogenesis factor175656737578398Rat
1303141Phactr2phosphatase and actin regulator 2175912547860431Rat
1303053Fuca2alpha-L-fucosidase 2178859867900777Rat
621636Pex3peroxisomal biogenesis factor 3179125087954474Rat
1309642Adat2adenosine deaminase, tRNA-specific 2179545207975254Rat
40957964LOC120098785uncharacterized LOC120098785180216018025425Rat
40944528Cfl1-ps8cofilin 1, pseudogene 8180262218031917Rat
1562920Aig1androgen-induced 1180464308269276Rat
61988Hivep2HIVEP zinc finger 2183582058555993Rat
41295609Rpl13a-ps9ribosomal protein L13A, pseudogene 9184240878425747Rat
41021964Trnaa-agc27transfer RNA alanine (anticodon AGC) 27186529468653026Rat
6486936C1h3orf38similar to human chromosome 3 open reading frame 38186842558685096Rat
1308551Adgrg6adhesion G protein-coupled receptor G6188128898954239Rat
11430648LOC108349488uncharacterized LOC108349488189768408984115Rat
1305031Vta1vesicle trafficking 1190328619080635Rat
9117395LOC103690921uncharacterized LOC103690921190806609091019Rat
1598009Gje1gap junction protein, epsilon 1190857899088204Rat
3181Nmbrneuromedin B receptor191150339146081Rat
41355366LOC120100430small nucleolar RNA SNORA17193835239383653Rat
7687370LOC102552144uncharacterized LOC102552144196839259743071Rat
7594200LOC102552210uncharacterized LOC10255221011001495210025253Rat
11426093LOC108349489uncharacterized LOC10834948911002570410057894Rat
40971154LOC120100212U7 small nuclear RNA11037737810377442Rat
41277239LOC120100214U7 small nuclear RNA11037918910379250Rat
41275469LOC120100489U2 spliceosomal RNA11064428310644402Rat
7576411LOC102552459uncharacterized LOC10255245911078268410845437Rat
41195942LOC120098787uncharacterized LOC12009878711084522710887107Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
34449D1Mgh17136186064968606632Ratregion
36137D1Rat516211043533910435501Ratregion
36199D1Rat112911024655010246679Ratregion
37610D1Rat167229141628074163036Ratregion
37658D1Rat247216162366426236858Ratregion
36568D1Rat417011148131211481482Ratregion
35146D1Rat2137146965614696698Ratregion
39234D1Rat248241159258775926118Ratregion
42442D1Rat38794144590394459133Ratregion
42443D1Rat388225180864688086692Ratregion
40880D1Rat249241178166717816912Ratregion
41808D1Rat328141196554079655550Ratregion
41870D1Rat327231178182617818492Ratregion
43170D1Got3217152404535240670Ratregion
43171D1Got4197144358344436033Ratregion
43172D1Got6206167655846766052Ratregion
43172D1Got6206167658466766052Ratregion
43173D1Got7127173509927351121Ratregion
43174D1Got8230185281138528343Ratregion
43175D1Mgh16155159258745926029Ratregion
60254D1Got5210165973546597559Ratregion
62435D1Uia13274167402216740495Ratregion
67300D1Arb40328150609455061273Ratregion
1629050D1Got366125184031288403253Ratregion
5037085RH78408184185548808555064Ratregion
5035675RH47174134188296218829755Ratregion
5026724RH133293180190331469033326Ratregion
5029407RH144675163141852834185446Ratregion
5029506GRM1227150609425061169Ratregion
5030261BE105044170155589705559140Ratregion
5027793RH94761179191452799145458Ratregion
5056429RH144373118190314499031567Ratregion
5051941RH94747123167227036722826Ratregion
5055285RH143713100180464868046586Ratregion
5055323RH143735112167925046792616Ratregion
5058936AI071143208141826304182838Ratregion
5053263RH142547285156655445665829Ratregion
5053765RH142838126183691798369305Ratregion
5052993RH142392168173571547357322Ratregion
5041602RH128951191180464848046675Ratregion
5044646RH130723220190274459027665Ratregion
5049350RH133430190188151148815304Ratregion
5039396RH127681204149015834901786Ratregion
5049622RH133586193179750417975234Ratregion
5039532RH127759180155269565527128Ratregion
5040382RH128251217175914877591704Ratregion
5041186RH128712179180468138046992Ratregion
5072118RH136661185170833667083551Ratregion
5075260RH138492200185223148522514Ratregion
5077938RH140046205175971967597401Ratregion
5080456RH141589216179127317912947Ratregion
5078822RH140572184175019217502105Ratregion
5070550RH134566212175657917566003Ratregion
5071886RH135342192156019955602187Ratregion
5072422RH136840136149462544946390Ratregion
5067730AU047570123163813276381450Ratregion
5061918BE112042155175954737595628Ratregion
5062050BI294821150176379097638059Ratregion
5063826AW535543168186010108601178Ratregion
5063768AW535138185181419688142153Ratregion
5065506BE109160150171725417172691Ratregion
5066258PMC126259P698185540878554185Ratregion
5063284BI301647210174877037487913Ratregion
5066550AU048290140174486597448799Ratregion
5086871BM387506155181995728199727Ratregion
5082109BF409594121184615038461624Ratregion
5090815AU049979216165973546597568Ratregion
5089675AU049296224190744119074635Ratregion
5090607AU049853235171338617134098Ratregion
5084170AA893893138179742527974390Ratregion
5085179BQ195664165178117587811923Ratregion
5082907BF390393220142796064279826Ratregion
5084896AA85190196188117318811827Ratregion
5085302BQ195873207180525668052773Ratregion
5502660Z19543194157639365764130Ratregion
5505550GDB:4585461467151130785113543Ratregion
5500035UniSTS:236306272141830574183328Ratregion
5502742UMNe5070181268248127512Ratregion
5502742UMNe5070181270328127512Ratregion
5506897G47430212158271475827359Ratregion
Position Markers

Flank 1: (D1Rat167)
Rat AssemblyChrPosition (strand)Source
GRCr815,983,050 - 5,983,279 (+)Marker Load Pipeline
mRatBN7.214,162,807 - 4,163,036 (+)MAPPER
Rnor_6.013,839,159 - 3,839,387NCBI
Rnor_5.015,511,572 - 5,511,800UniSTS
RGSC_v3.414,404,877 - 4,405,106RGD
RGSC_v3.414,404,878 - 4,405,106UniSTS
RGSC_v3.114,404,878 - 4,405,106RGD
Celera12,703,107 - 2,703,335UniSTS
RH 3.4 Map176.9UniSTS
RH 3.4 Map176.9RGD
RH 2.0 Map10.0RGD
SHRSP x BN Map11.3699RGD
Peak: (D1Rat167)
Rat AssemblyChrPosition (strand)Source
GRCr815,983,050 - 5,983,279 (+)Marker Load Pipeline
mRatBN7.214,162,807 - 4,163,036 (+)MAPPER
Rnor_6.013,839,159 - 3,839,387NCBI
Rnor_5.015,511,572 - 5,511,800UniSTS
RGSC_v3.414,404,877 - 4,405,106RGD
RGSC_v3.414,404,878 - 4,405,106UniSTS
RGSC_v3.114,404,878 - 4,405,106RGD
Celera12,703,107 - 2,703,335UniSTS
RH 3.4 Map176.9UniSTS
RH 3.4 Map176.9RGD
RH 2.0 Map10.0RGD
SHRSP x BN Map11.3699RGD
Flank 2: (D1Rat4)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2111,481,312 - 11,481,482 (+)MAPPER
Rnor_6.0111,314,489 - 11,314,658NCBI
Rnor_5.0112,920,106 - 12,920,275UniSTS
RGSC_v3.4111,859,997 - 11,860,328RGD
RGSC_v3.4111,860,049 - 11,860,218UniSTS
RGSC_v3.1111,860,049 - 11,860,218RGD
Celera19,949,930 - 9,950,099UniSTS
RH 3.4 Map1131.2UniSTS
RH 3.4 Map1131.2RGD
RH 2.0 Map146.9RGD
SHRSP x BN Map19.25RGD
FHH x ACI Map17.84RGD


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124744506Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128736750Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11148148232355910Rat
1300170Rf6Renal function QTL 63.14renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)1416280711481482Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1132356093Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1592587724697545Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Rf6

RGD Curation Notes
Note Type Note Reference
qtl_general additional information, including phenotype and mapping information, can be found at Genomic Map of Cardiovascular Phenotypes 727992
qtl_general relative renal blood flow after angiotensin II administration, divided by kidney weight in grams 727992