Utrn (utrophin) - Rat Genome Database

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Gene: Utrn (utrophin) Rattus norvegicus
Analyze
Symbol: Utrn
Name: utrophin
RGD ID: 3947
Description: Enables actin filament binding activity. Involved in neuromuscular junction development and response to denervation involved in regulation of muscle adaptation. Located in cortical actin cytoskeleton; growth cone; and neuromuscular junction. Orthologous to human UTRN (utrophin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DRP-1; dystrophin-related protein 1; utrophin (homologous to dystrophin)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.216,720,854 - 7,224,313 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl16,722,594 - 7,224,313 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx16,424,644 - 6,925,694 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0112,423,666 - 12,924,754 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.016,706,883 - 7,207,935 (-)NCBIRnor_WKY
Rnor_6.016,451,809 - 6,970,040 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl16,451,810 - 6,970,040 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.018,097,013 - 8,608,996 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.417,099,840 - 7,614,980 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.117,099,839 - 7,614,980 (-)NCBI
Celera15,228,645 - 5,725,909 (-)NCBICelera
RH 3.4 Map1104.42RGD
Cytogenetic Map1p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
apigenin  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-naphthoflavone  (EXP)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
chrysin  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
clorgyline  (ISO)
clothianidin  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dibenz[a,h]anthracene  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
equilin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenamidone  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
furan  (EXP)
gallic acid  (ISO)
glyphosate  (EXP)
hesperetin  (ISO)
ivermectin  (ISO)
kaempferol  (ISO)
leflunomide  (ISO)
methamphetamine  (ISO)
methyl methanesulfonate  (ISO)
methylseleninic acid  (ISO)
mitoxantrone  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nabumetone  (ISO)
ozone  (EXP)
paracetamol  (ISO)
pentanal  (ISO)
phenazopyridine  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
piperine  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
quinolin-8-ol  (ISO)
resveratrol  (ISO)
Riluzole  (ISO)
SB 431542  (ISO)
sodium dichromate  (EXP)
succimer  (ISO)
tetraphene  (ISO)
thiabendazole  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Increased expression of dystrophin, beta-dystroglycan and adhalin in denervated rat muscles. Biral D, etal., J Muscle Res Cell Motil. 1996 Oct;17(5):523-32.
2. Different dystrophin-like complexes are expressed in neurons and glia. Blake DJ, etal., J Cell Biol. 1999 Nov 1;147(3):645-58. doi: 10.1083/jcb.147.3.645.
3. Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy. Deconinck AE, etal., Cell 1997 Aug 22;90(4):717-27.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Differential expression of dystrophin isoforms and utrophin during dibutyryl-cAMP-induced morphological differentiation of rat brain astrocytes. Imamura M and Ozawa E, Proc Natl Acad Sci U S A 1998 May 26;95(11):6139-44.
7. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Expression and localization of utrophin in differentiating PC12 cells. Rosas-Vargas H, etal., Neuroreport. 2000 Jul 14;11(10):2253-7.
14. Proteomics success story. Towards early detection of breast and ovarian cancer: plasma proteomics as a tool to find novel markers. Souchelnytskyi S, etal., Proteomics. 2006 Sep;6 Suppl 2:65-8.
15. An atomic model for actin binding by the CH domains and spectrin-repeat modules of utrophin and dystrophin. Sutherland-Smith AJ, etal., J Mol Biol. 2003 May 23;329(1):15-33.
16. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
17. Utrophin mRNA expression in muscle is not restricted to the neuromuscular junction. Vater R, etal., Mol Cell Neurosci 1998 Apr;10(5-6):229-42.
18. Identification and characterisation of transcript and protein of a new short N-terminal utrophin isoform. Zuellig RA, etal., J Cell Biochem. 2000 Apr;77(3):418-31.
Additional References at PubMed
PMID:1461282   PMID:7890770   PMID:9674605   PMID:10995443   PMID:11043403   PMID:12808150   PMID:15501597   PMID:15963030   PMID:16803572   PMID:17119023   PMID:18468998   PMID:19056867  
PMID:19786618   PMID:21192954   PMID:22228988  


Genomics

Comparative Map Data
Utrn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.216,720,854 - 7,224,313 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl16,722,594 - 7,224,313 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx16,424,644 - 6,925,694 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0112,423,666 - 12,924,754 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.016,706,883 - 7,207,935 (-)NCBIRnor_WKY
Rnor_6.016,451,809 - 6,970,040 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl16,451,810 - 6,970,040 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.018,097,013 - 8,608,996 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.417,099,840 - 7,614,980 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.117,099,839 - 7,614,980 (-)NCBI
Celera15,228,645 - 5,725,909 (-)NCBICelera
RH 3.4 Map1104.42RGD
Cytogenetic Map1p13NCBI
UTRN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386144,285,335 - 144,853,034 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl6144,285,335 - 144,853,034 (+)EnsemblGRCh38hg38GRCh38
GRCh376144,606,471 - 145,174,170 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366144,654,566 - 145,215,863 (+)NCBINCBI36Build 36hg18NCBI36
Build 346144,654,657 - 145,209,657NCBI
Celera6145,353,235 - 145,914,469 (+)NCBICelera
Cytogenetic Map6q24.2NCBI
HuRef6142,176,382 - 142,737,622 (+)NCBIHuRef
CHM1_16144,875,601 - 145,437,493 (+)NCBICHM1_1
T2T-CHM13v2.06145,477,963 - 146,045,651 (+)NCBIT2T-CHM13v2.0
Utrn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391012,257,931 - 12,745,632 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1012,257,932 - 12,745,109 (-)EnsemblGRCm39 Ensembl
GRCm381012,382,187 - 12,869,888 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1012,382,188 - 12,869,365 (-)EnsemblGRCm38mm10GRCm38
MGSCv371012,101,986 - 12,581,533 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361012,073,568 - 12,551,836 (-)NCBIMGSCv36mm8
Celera1012,282,524 - 12,766,578 (-)NCBICelera
Cytogenetic Map10A1NCBI
cM Map103.77NCBI
Utrn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543615,730,020 - 16,231,919 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543615,730,416 - 16,237,379 (-)NCBIChiLan1.0ChiLan1.0
UTRN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16146,786,654 - 147,353,226 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6146,793,153 - 147,351,210 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06142,069,139 - 142,636,507 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
UTRN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1135,727,531 - 36,225,533 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl135,677,814 - 36,224,065 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha136,627,086 - 37,115,507 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0135,906,556 - 36,401,715 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl135,845,084 - 36,401,052 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1135,775,436 - 36,264,006 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0135,651,671 - 36,139,451 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0135,969,567 - 36,458,179 (+)NCBIUU_Cfam_GSD_1.0
Utrn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946130,636,043 - 131,145,229 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366251,489,696 - 1,894,813 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049366251,490,327 - 1,999,428 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UTRN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl120,514,260 - 21,048,484 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1120,514,264 - 21,047,927 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2122,999,397 - 23,103,391 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UTRN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11328,354,810 - 28,949,508 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1328,354,588 - 28,944,119 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040564,242 - 1,085,338 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Utrn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247539,554,240 - 9,984,058 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247539,548,914 - 10,090,635 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Utrn
3433 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:297
Count of miRNA genes:196
Interacting mature miRNAs:212
Transcripts:ENSRNOT00000016273
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124744506Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128736750Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)1132356093Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)150910843284926Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
1300170Rf6Renal function QTL 63.14renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)1416280711481482Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1592587724697545Rat

Markers in Region
D1Got6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.216,765,584 - 6,766,052 (+)MAPPERmRatBN7.2
mRatBN7.216,765,846 - 6,766,052 (+)MAPPERmRatBN7.2
Rnor_6.016,497,143 - 6,497,348NCBIRnor6.0
Rnor_6.016,496,800 - 6,497,348NCBIRnor6.0
Rnor_5.018,142,004 - 8,142,552UniSTSRnor5.0
Rnor_5.018,142,347 - 8,142,552UniSTSRnor5.0
RGSC_v3.417,143,101 - 7,143,306UniSTSRGSC3.4
RGSC_v3.417,143,100 - 7,143,306RGDRGSC3.4
RGSC_v3.117,143,100 - 7,143,306RGD
Celera15,271,833 - 5,272,038UniSTS
RH 3.4 Map1124.81UniSTS
RH 3.4 Map1124.81RGD
RH 2.0 Map10.0RGD
Cytogenetic Map1p13UniSTS
D1Uia13  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.216,740,221 - 6,740,495 (+)MAPPERmRatBN7.2
Rnor_6.016,471,175 - 6,471,448NCBIRnor6.0
Rnor_5.018,116,379 - 8,116,652UniSTSRnor5.0
RGSC_v3.417,117,475 - 7,117,749RGDRGSC3.4
RGSC_v3.417,117,476 - 7,117,749UniSTSRGSC3.4
RGSC_v3.117,117,475 - 7,117,749RGD
Celera15,246,236 - 5,246,509UniSTS
Cytogenetic Map1p13UniSTS
RH94747  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.216,722,703 - 6,722,826 (+)MAPPERmRatBN7.2
Rnor_6.016,453,659 - 6,453,781NCBIRnor6.0
Rnor_5.018,098,863 - 8,098,985UniSTSRnor5.0
RGSC_v3.417,099,950 - 7,100,072UniSTSRGSC3.4
Celera15,228,755 - 5,228,877UniSTS
RH 3.4 Map1104.42UniSTS
Cytogenetic Map1p13UniSTS
RH143735  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.216,792,504 - 6,792,616 (+)MAPPERmRatBN7.2
Rnor_6.016,522,601 - 6,522,712NCBIRnor6.0
Rnor_5.018,167,805 - 8,167,916UniSTSRnor5.0
RGSC_v3.417,169,769 - 7,169,880UniSTSRGSC3.4
Celera15,298,438 - 5,298,549UniSTS
RH 3.4 Map1124.02UniSTS
Cytogenetic Map1p13UniSTS
BE109160  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.217,172,541 - 7,172,691 (+)MAPPERmRatBN7.2
Rnor_6.016,915,425 - 6,915,574NCBIRnor6.0
Rnor_5.018,557,343 - 8,557,492UniSTSRnor5.0
RGSC_v3.417,561,246 - 7,561,395UniSTSRGSC3.4
Celera15,673,854 - 5,674,003UniSTS
RH 3.4 Map1115.0UniSTS
Cytogenetic Map1p13UniSTS
RH136661  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.217,083,366 - 7,083,551 (+)MAPPERmRatBN7.2
Rnor_6.016,827,462 - 6,827,646NCBIRnor6.0
Rnor_5.018,470,653 - 8,470,837UniSTSRnor5.0
RGSC_v3.417,470,622 - 7,470,806UniSTSRGSC3.4
Celera15,585,382 - 5,585,566UniSTS
RH 3.4 Map1109.9UniSTS
Cytogenetic Map1p13UniSTS
AU049853  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.217,133,861 - 7,134,098 (+)MAPPERmRatBN7.2
Rnor_6.016,876,823 - 6,877,057NCBIRnor6.0
Rnor_5.018,519,645 - 8,519,879UniSTSRnor5.0
RGSC_v3.417,521,719 - 7,521,953UniSTSRGSC3.4
Celera15,635,696 - 5,635,920UniSTS
Cytogenetic Map1p13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 30 14 19 14 8 8 70 35 36 11 8
Low 1 27 27 27 3 4 5
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_013070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005500256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB011666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ002967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000016273   ⟹   ENSRNOP00000016273
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl16,722,594 - 7,224,313 (-)Ensembl
Rnor_6.0 Ensembl16,453,549 - 6,970,040 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086574   ⟹   ENSRNOP00000069754
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl16,722,594 - 7,160,451 (-)Ensembl
Rnor_6.0 Ensembl16,451,810 - 6,903,486 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110204   ⟹   ENSRNOP00000093686
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl16,722,594 - 7,224,313 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110380   ⟹   ENSRNOP00000080968
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl16,722,594 - 6,887,171 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110616   ⟹   ENSRNOP00000092740
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl16,722,594 - 6,956,460 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112052   ⟹   ENSRNOP00000085259
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl16,722,594 - 7,174,506 (-)Ensembl
RefSeq Acc Id: NM_013070   ⟹   NP_037202
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,722,594 - 7,224,313 (-)NCBI
Rnor_6.016,453,549 - 6,970,040 (-)NCBI
Rnor_5.018,097,013 - 8,608,996 (-)NCBI
RGSC_v3.417,099,840 - 7,614,980 (-)RGD
Celera15,228,645 - 5,725,909 (-)RGD
Sequence:
RefSeq Acc Id: XM_006227637   ⟹   XP_006227699
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,720,854 - 7,162,810 (-)NCBI
Rnor_6.016,451,809 - 6,905,681 (-)NCBI
Rnor_5.018,097,013 - 8,608,996 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008758593   ⟹   XP_008756815
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,720,854 - 7,223,721 (-)NCBI
Rnor_6.016,451,809 - 6,969,464 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008758594   ⟹   XP_008756816
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,720,854 - 7,224,149 (-)NCBI
Rnor_6.016,451,809 - 6,969,839 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008758595   ⟹   XP_008756817
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,720,854 - 7,162,810 (-)NCBI
Rnor_6.016,451,809 - 6,905,681 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008758596   ⟹   XP_008756818
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,720,854 - 7,174,742 (-)NCBI
Rnor_6.016,451,809 - 6,917,636 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008758598   ⟹   XP_008756820
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,720,854 - 6,958,646 (-)NCBI
Rnor_6.016,451,809 - 6,696,898 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008758599   ⟹   XP_008756821
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,720,854 - 6,887,564 (-)NCBI
Rnor_6.016,451,809 - 6,626,093 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017588826   ⟹   XP_017444315
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,720,854 - 7,088,686 (-)NCBI
Rnor_6.016,451,809 - 6,832,770 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039101947   ⟹   XP_038957875
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,720,854 - 7,187,680 (-)NCBI
RefSeq Acc Id: XM_039101949   ⟹   XP_038957877
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,720,854 - 7,188,172 (-)NCBI
RefSeq Acc Id: XM_039101956   ⟹   XP_038957884
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,720,854 - 7,085,389 (-)NCBI
RefSeq Acc Id: XM_039101962   ⟹   XP_038957890
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,971,465 - 7,162,812 (-)NCBI
RefSeq Acc Id: XR_005500256
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.216,720,854 - 7,162,811 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_037202   ⟸   NM_013070
- UniProtKB: G3V7L1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006227699   ⟸   XM_006227637
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JW60 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008756816   ⟸   XM_008758594
- Peptide Label: isoform X2
- UniProtKB: G3V7L1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008756815   ⟸   XM_008758593
- Peptide Label: isoform X2
- UniProtKB: G3V7L1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008756818   ⟸   XM_008758596
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZYU2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008756817   ⟸   XM_008758595
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008756820   ⟸   XM_008758598
- Peptide Label: isoform X9
- UniProtKB: A0A8I6AE90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008756821   ⟸   XM_008758599
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZS09 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444315   ⟸   XM_017588826
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: ENSRNOP00000016273   ⟸   ENSRNOT00000016273
RefSeq Acc Id: ENSRNOP00000069754   ⟸   ENSRNOT00000086574
RefSeq Acc Id: XP_038957877   ⟸   XM_039101949
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038957875   ⟸   XM_039101947
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038957884   ⟸   XM_039101956
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038957890   ⟸   XM_039101962
- Peptide Label: isoform X8
RefSeq Acc Id: ENSRNOP00000080968   ⟸   ENSRNOT00000110380
RefSeq Acc Id: ENSRNOP00000093686   ⟸   ENSRNOT00000110204
RefSeq Acc Id: ENSRNOP00000092740   ⟸   ENSRNOT00000110616
RefSeq Acc Id: ENSRNOP00000085259   ⟸   ENSRNOT00000112052
Protein Domains
Calponin-homology (CH)   WW   ZZ-type

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3947 AgrOrtholog
BioCyc Gene G2FUF-62382 BioCyc
Ensembl Genes ENSRNOG00000011058 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000016273 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000069754 ENTREZGENE
  ENSRNOP00000069754.1 UniProtKB/TrEMBL
  ENSRNOP00000080968 ENTREZGENE
  ENSRNOP00000080968.1 UniProtKB/TrEMBL
  ENSRNOP00000085259 ENTREZGENE
  ENSRNOP00000085259.1 UniProtKB/TrEMBL
  ENSRNOP00000092740 ENTREZGENE
  ENSRNOP00000092740.1 UniProtKB/TrEMBL
  ENSRNOP00000093686.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016273 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000086574 ENTREZGENE
  ENSRNOT00000086574.2 UniProtKB/TrEMBL
  ENSRNOT00000110204.1 UniProtKB/TrEMBL
  ENSRNOT00000110380 ENTREZGENE
  ENSRNOT00000110380.1 UniProtKB/TrEMBL
  ENSRNOT00000110616 ENTREZGENE
  ENSRNOT00000110616.1 UniProtKB/TrEMBL
  ENSRNOT00000112052 ENTREZGENE
  ENSRNOT00000112052.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.60.90 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Actinin_actin-bd_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calponin-like_dom_sf UniProtKB/TrEMBL
  CH-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/Swiss-Prot
  Dystrophin/utrophin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand_dom_typ1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand_dom_typ2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin/alpha-actinin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WW_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_ZZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_ZZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25600 UniProtKB/TrEMBL
NCBI Gene 25600 ENTREZGENE
Pfam EF-hand_2 UniProtKB/Swiss-Prot
  EF-hand_3 UniProtKB/Swiss-Prot
  efhand_1 UniProtKB/TrEMBL
  efhand_2 UniProtKB/TrEMBL
  PF00307 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00397 UniProtKB/TrEMBL
  PF00569 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Utrn PhenoGen
PIRSF Dystrophin/utrophin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ACTININ_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ACTININ_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50021 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WW_DOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_ZZ_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_ZZ_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00033 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00456 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPEC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_ZZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Calponin-homology UniProtKB/TrEMBL
  SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47576 UniProtKB/Swiss-Prot
  SSF51045 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC237592
UniProt A0A0G2JW60 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZS09 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYU2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AE90 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AG96_RAT UniProtKB/TrEMBL
  G3V7L1 ENTREZGENE
  O55147_RAT UniProtKB/TrEMBL
  UTRN_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Utrn  Utrophin      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in nondifferentiated rat brain astrocytes 634447