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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:microRNA pathway
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Accession:PW:0000808 term browser browse the term
Definition:MicroRNAs (miRNAs) are a large family of small RNAs involved in the post-transcriptional regulation of gene expression. The biogenesis and function of miRNA is subject to complex control. Deregulation of miRNA expression has been linked to many diseases including cancer.
Synonyms:related_synonym: MicroRNA (miRNA) biogenesis;   miRNA pathway;   production of miRNAs involved in gene silencing by miRNA
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microRNA pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific ISO RGD PMID:22001383 RGD:9850105 NCBI chr 3:89,622,321...89,660,756
Ensembl chr 3:89,622,329...89,660,753 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 ISO RGD PMID:22001383 RGD:9850105 NCBI chr10:77,126,561...77,254,125
Ensembl chr10:77,126,560...77,254,104 		JBrowse link
G Ago1 argonaute RISC catalytic subunit 1 ISO RGD PMID:20484662 RGD:4144862 NCBI chr 4:126,328,805...126,362,500
Ensembl chr 4:126,328,805...126,362,376 		JBrowse link
G Ago2 argonaute RISC catalytic subunit 2 ISO RGD PMID:20484662 RGD:4144862 NCBI chr15:72,967,693...73,056,777
Ensembl chr15:72,967,693...73,056,784 		JBrowse link
G Ago3 argonaute RISC catalytic subunit 3 ISO RGD PMID:20484662 RGD:4144862 NCBI chr 4:126,220,797...126,323,360
Ensembl chr 4:126,225,497...126,323,349 		JBrowse link
G Ago4 argonaute RISC catalytic subunit 4 ISO RGD PMID:20484662 RGD:4144862 NCBI chr 4:126,383,280...126,427,379
Ensembl chr 4:126,383,334...126,427,265 		JBrowse link
G Cnot1 CCR4-NOT transcription complex, subunit 1 ISO RGD PMID:23337855 RGD:9850101 NCBI chr 8:96,445,559...96,534,741
Ensembl chr 8:96,446,079...96,534,092 		JBrowse link
G Cnot10 CCR4-NOT transcription complex, subunit 10 ISO RGD PMID:23337855 RGD:9850101 NCBI chr 9:114,414,942...114,469,289
Ensembl chr 9:114,414,946...114,469,252 		JBrowse link
G Cnot2 CCR4-NOT transcription complex, subunit 2 ISO RGD PMID:23337855 RGD:9850101 NCBI chr10:116,321,065...116,418,891
Ensembl chr10:116,321,066...116,417,416 		JBrowse link
G Cnot3 CCR4-NOT transcription complex, subunit 3 ISO RGD PMID:23337855 RGD:9850101 NCBI chr 7:3,646,717...3,664,108
Ensembl chr 7:3,648,267...3,664,108 		JBrowse link
G Cnot6 CCR4-NOT transcription complex, subunit 6 ISO RGD PMID:23337855 RGD:9850101 NCBI chr11:49,562,324...49,604,227
Ensembl chr11:49,562,330...49,603,550 		JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like ISO RGD PMID:23337855 RGD:9850101 NCBI chr 5:96,218,192...96,312,044
Ensembl chr 5:96,218,192...96,312,030 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 ISO RGD PMID:23337855 RGD:9850101 NCBI chr 8:40,945,579...40,968,888
Ensembl chr 8:40,945,581...40,968,888 		JBrowse link
G Cnot8 CCR4-NOT transcription complex, subunit 8 ISO RGD PMID:23337855 RGD:9850101 NCBI chr11:57,983,620...58,009,423
Ensembl chr11:57,994,979...58,009,420 		JBrowse link
G Cnot9 CCR4-NOT transcription complex, subunit 9 ISO RGD PMID:23337855 RGD:9850101 NCBI chr 1:74,545,192...74,570,001
Ensembl chr 1:74,545,217...74,570,001 		JBrowse link
G Dcp1b decapping mRNA 1B ISO RGD PMID:24352420 RGD:9850104 NCBI chr 6:119,152,214...119,198,575
Ensembl chr 6:119,152,214...119,198,577 		JBrowse link
G Dcp2 decapping mRNA 2 ISO RGD PMID:24352420 RGD:9850104 NCBI chr18:44,513,567...44,558,036
Ensembl chr18:44,513,569...44,558,036 		JBrowse link
G Ddx6 DEAD-box helicase 6 ISO RGD PMID:24352420 RGD:9850104 NCBI chr 9:44,514,113...44,552,028
Ensembl chr 9:44,516,189...44,552,028 		JBrowse link
G Dgcr8 DGCR8, microprocessor complex subunit ISO RGD PMID:20661255 RGD:4144851 NCBI chr16:18,071,812...18,107,115
Ensembl chr16:18,071,812...18,107,110 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III ISO RGD PMID:20661255 RGD:4144851 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Drosha drosha, ribonuclease type III ISO RGD PMID:20661255 RGD:4144851 NCBI chr15:12,824,893...12,935,377
Ensembl chr15:12,824,901...12,935,377 		JBrowse link
G Edc3 enhancer of mRNA decapping 3 ISO RGD PMID:24352420 RGD:9850104 NCBI chr 9:57,615,823...57,659,782
Ensembl chr 9:57,615,823...57,659,782 		JBrowse link
G Edc4 enhancer of mRNA decapping 4 ISO RGD PMID:24352420 RGD:9850104 NCBI chr 8:106,607,506...106,619,857
Ensembl chr 8:106,607,513...106,621,540 		JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 ISO RGD PMID:23337855 RGD:9850101 NCBI chr15:36,595,902...36,609,825
Ensembl chr15:36,595,905...36,609,912 		JBrowse link
G Pan2 PAN2 poly(A) specific ribonuclease subunit ISO RGD PMID:23337855 RGD:9850101 NCBI chr10:128,135,106...128,157,227
Ensembl chr10:128,139,204...128,157,227 		JBrowse link
G Pan3 PAN3 poly(A) specific ribonuclease subunit ISO RGD PMID:23337855 RGD:9850101 NCBI chr 5:147,363,018...147,485,310
Ensembl chr 5:147,366,971...147,485,312 		JBrowse link
G Patl1 protein associated with topoisomerase II homolog 1 (yeast) ISO RGD PMID:24352420 RGD:9850104 NCBI chr19:11,889,728...11,922,462
Ensembl chr19:11,889,763...11,922,455 		JBrowse link
G Ran RAN, member RAS oncogene family ISO RGD PMID:19965479 RGD:4144860 NCBI chr 5:129,097,264...129,101,388
Ensembl chr 5:129,097,133...129,101,387 		JBrowse link
G Tarbp2 TARBP2, RISC loading complex RNA binding subunit ISO RGD PMID:20661255 RGD:4144851 NCBI chr15:102,423,327...102,432,112
Ensembl chr15:102,426,627...102,432,111 		JBrowse link
G Tnrc6a trinucleotide repeat containing 6a ISO RGD PMID:20484662 RGD:4144862 NCBI chr 7:122,630,324...122,794,519
Ensembl chr 7:122,723,108...122,794,519 		JBrowse link
G Tnrc6b trinucleotide repeat containing 6b ISO RGD PMID:20484662 RGD:4144862 NCBI chr15:80,595,514...80,825,287
Ensembl chr15:80,595,514...80,825,286 		JBrowse link
G Tnrc6c trinucleotide repeat containing 6C ISO RGD PMID:20484662 RGD:4144862 NCBI chr11:117,544,529...117,654,265
Ensembl chr11:117,545,115...117,654,265 		JBrowse link
G Tut4 terminal uridylyl transferase 4 ISO RGD PMID:23622238 RGD:9850106 NCBI chr 4:108,316,607...108,416,612
Ensembl chr 4:108,316,623...108,416,618 		JBrowse link
G Tut7 terminal uridylyl transferase 7 ISO RGD PMID:23622238 RGD:9850106 NCBI chr13:59,919,690...59,971,060
Ensembl chr13:59,919,375...59,970,961 		JBrowse link
G Xpo5 exportin 5 ISO RGD PMID:19965479 RGD:4144860 NCBI chr17:46,513,737...46,554,524
Ensembl chr17:46,513,708...46,554,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6072
    regulatory pathway 3689
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1669
        non-coding RNA pathway 35
          small non-coding RNA pathway 35
            microRNA pathway 35
              altered microRNA pathway 0
paths to the root