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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (S)-nicotine | increases expression | ISO | RGD:1320865 | 6480464 | Nicotine results in increased expression of TUT4 mRNA | CTD | PMID:16949557 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of TUT4 mRNA | CTD | PMID:22206623 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | RGD:1310138 | 6480464 | 2 more ... | CTD | PMID:21394737 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1310138 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TUT4 mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TUT4 mRNA | CTD | PMID:28922406 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1310138 | 6480464 | Tetrachlorodibenzodioxin affects the expression of TUT4 mRNA | CTD | PMID:22298810, PMID:34747641 | 3,4-methylenedioxymethamphetamine | decreases expression | EXP | | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of TUT4 mRNA | CTD | PMID:20188158 | 4,4'-sulfonyldiphenol | increases methylation | ISO | RGD:1320865 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased methylation of TUT4 gene | CTD | PMID:31601247 | acetamide | decreases expression | ISO | RGD:1310138 | 6480464 | acetamide results in decreased expression of TUT4 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | RGD:1310138 | 6480464 | Acrylamide results in decreased expression of TUT4 mRNA | CTD | PMID:28959563 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of TUT4 mRNA | CTD | PMID:30807115 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of TUT4 mRNA | CTD | PMID:19770486 | antirheumatic drug | increases expression | ISO | RGD:1320865 | 6480464 | Antirheumatic Agents results in increased expression of TUT4 mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | ISO | RGD:1320865 | 6480464 | aristolochic acid I results in decreased expression of TUT4 mRNA | CTD | PMID:33212167 | atrazine | increases expression | ISO | RGD:1320865 | 6480464 | Atrazine results in increased expression of TUT4 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | affects methylation | ISO | RGD:1320865 | 6480464 | Benzo(a)pyrene affects the methylation of TUT4 intron | CTD | PMID:30157460 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:1320865 | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | decreases expression | ISO | RGD:1320865 | 6480464 | bisphenol A results in decreased expression of TUT4 mRNA | CTD | PMID:20678512 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TUT4 mRNA | CTD | PMID:35598803 | bisphenol A | multiple interactions | ISO | RGD:1320865 | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of TUT4 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TUT4 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | ISO | RGD:1320865 | 6480464 | bisphenol A results in increased expression of TUT4 mRNA | CTD | PMID:29275510, PMID:33670352 | bisphenol A | increases expression | ISO | RGD:1310138 | 6480464 | bisphenol A results in increased expression of TUT4 mRNA | CTD | PMID:25181051 more ... | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681, PMID:25620056 | CGP 52608 | multiple interactions | ISO | RGD:1320865 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TUT4 gene] | CTD | PMID:28238834 | chloroprene | increases expression | ISO | RGD:1310138 | 6480464 | Chloroprene results in increased expression of TUT4 mRNA | CTD | PMID:23125180 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of TUT4 gene | CTD | PMID:20938992 | cocaine | decreases expression | ISO | RGD:1310138 | 6480464 | Cocaine results in decreased expression of TUT4 mRNA | CTD | PMID:17898221 | copper(II) sulfate | decreases expression | ISO | RGD:1320865 | 6480464 | Copper Sulfate results in decreased expression of TUT4 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | RGD:1320865 | 6480464 | Cyclosporine results in increased expression of TUT4 mRNA | CTD | PMID:20106945 | dorsomorphin | multiple interactions | ISO | RGD:1320865 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | RGD:1320865 | 6480464 | Doxorubicin results in decreased expression of TUT4 mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | RGD:1320865 | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of TUT4 protein | CTD | PMID:23301498 | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of TUT4 mRNA | CTD | PMID:29018328 | flutamide | decreases expression | ISO | RGD:1310138 | 6480464 | Flutamide results in decreased expression of TUT4 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of TUT4 gene | CTD | PMID:20938992 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of TUT4 mRNA | CTD | PMID:25629700 | fulvestrant | multiple interactions | ISO | RGD:1320865 | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of TUT4 gene | CTD | PMID:31601247 | gentamycin | increases expression | ISO | RGD:1310138 | 6480464 | Gentamicins results in increased expression of TUT4 mRNA | CTD | PMID:22061828 | glafenine | decreases expression | ISO | RGD:1310138 | 6480464 | Glafenine results in decreased expression of TUT4 mRNA | CTD | PMID:24136188 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of TUT4 gene | CTD | PMID:20938992 | methapyrilene | decreases expression | ISO | RGD:1310138 | 6480464 | Methapyrilene results in decreased expression of TUT4 mRNA | CTD | PMID:30467583 | nicotine | increases expression | ISO | RGD:1320865 | 6480464 | Nicotine results in increased expression of TUT4 mRNA | CTD | PMID:16949557 | oxaliplatin | multiple interactions | ISO | RGD:1310138 | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of TUT4 mRNA | CTD | PMID:25729387 | phenytoin | increases expression | ISO | RGD:1310138 | 6480464 | Phenytoin results in increased expression of TUT4 mRNA | CTD | PMID:20345932 | pirinixic acid | multiple interactions | ISO | RGD:1320865 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of TUT4 mRNA | CTD | PMID:19710929 | resveratrol | decreases expression | ISO | RGD:1310138 | 6480464 | resveratrol results in decreased expression of TUT4 mRNA | CTD | PMID:25905778 | SB 431542 | multiple interactions | ISO | RGD:1320865 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenate | decreases expression | EXP | | 6480464 | sodium arsenate results in decreased expression of TUT4 mRNA | CTD | PMID:30953684 | sunitinib | increases expression | ISO | RGD:1320865 | 6480464 | Sunitinib results in increased expression of TUT4 mRNA | CTD | PMID:31533062 | tetrachloromethane | decreases expression | ISO | RGD:1310138 | 6480464 | Carbon Tetrachloride results in decreased expression of TUT4 mRNA | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TUT4 mRNA | CTD | PMID:31919559 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of TUT4 mRNA | CTD | PMID:29264374 | topotecan | decreases expression | ISO | RGD:1310138 | 6480464 | Topotecan results in decreased expression of TUT4 mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | ISO | RGD:1310138 | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of TUT4 mRNA | CTD | PMID:25729387 | trichostatin A | decreases expression | ISO | RGD:1320865 | 6480464 | trichostatin A results in decreased expression of TUT4 mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | ISO | RGD:1320865 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TUT4 mRNA | CTD | PMID:27188386 | triptonide | affects expression | EXP | | 6480464 | triptonide affects the expression of TUT4 mRNA | CTD | PMID:33045310 | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of TUT4 mRNA | CTD | PMID:30912803 | valproic acid | decreases expression | ISO | RGD:1320865 | 6480464 | Valproic Acid results in decreased expression of TUT4 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | RGD:1320865 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TUT4 mRNA | CTD | PMID:27188386 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of TUT4 mRNA | CTD | PMID:17963808 | |