Tnrc6a (trinucleotide repeat containing 6a) - Rat Genome Database

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Gene: Tnrc6a (trinucleotide repeat containing 6a) Mus musculus
Analyze
Symbol: Tnrc6a
Name: trinucleotide repeat containing 6a
RGD ID: 1557944
MGI Page MGI
Description: Predicted to enable molecular adaptor activity. Acts upstream of or within cellular response to starvation and endoderm development. Predicted to be located in Golgi apparatus and perinuclear region of cytoplasm. Predicted to be part of RISC complex. Predicted to be active in P-body and nucleoplasm. Is expressed in several structures, including alimentary system; central nervous system; integumental system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 6. Orthologous to human TNRC6A (trinucleotide repeat containing adaptor 6A).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2010321I05Rik; 3110054G10Rik; AW557223; CAGH2; CAGH26; D130023A07Rik; GW182; GW182 autoantigen; MGC11932; Tnr; Tnrc6; trinucleotide repeat containing 6; trinucleotide repeat-containing gene 6A protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397122,630,324 - 122,794,519 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7122,723,108 - 122,794,519 (+)EnsemblGRCm39 Ensembl
GRCm387123,031,101 - 123,195,296 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7123,123,885 - 123,195,296 (+)EnsemblGRCm38mm10GRCm38
MGSCv377130,267,399 - 130,338,810 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367122,914,984 - 122,986,454 (+)NCBIMGSCv36mm8
Celera7123,004,629 - 123,075,878 (+)NCBICelera
Cytogenetic Map7F2- F3NCBI
cM Map767.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (EXP,ISO)
amiodarone  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
chlorpyrifos  (EXP)
choline  (EXP)
cobalt dichloride  (ISO)
cyclosporin A  (EXP,ISO)
cytarabine  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
fenthion  (EXP)
fenvalerate  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
gentamycin  (ISO)
hydrogen peroxide  (EXP)
hypochlorous acid  (EXP)
L-methionine  (EXP)
lead diacetate  (EXP,ISO)
lead(0)  (EXP)
leflunomide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (EXP)
methapyrilene  (ISO)
methidathion  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
propiconazole  (EXP)
SB 431542  (ISO)
scopolamine  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (EXP)
thioacetamide  (ISO)
toluene  (ISO)
topotecan  (ISO)
triptonide  (EXP)
triticonazole  (ISO)
troglitazone  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
zinc protoporphyrin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Argonaute proteins at a glance. Ender C and Meister G, J Cell Sci. 2010 Jun 1;123(Pt 11):1819-23.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10512203   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12520002   PMID:12904583   PMID:14610273   PMID:14621295   PMID:14681479   PMID:15494374  
PMID:15840001   PMID:16033648   PMID:16141072   PMID:16141073   PMID:16418578   PMID:17967808   PMID:18799693   PMID:19087264   PMID:19898466   PMID:20011505   PMID:20059948   PMID:20102707  
PMID:21873635   PMID:22187428   PMID:23604909   PMID:25568082   PMID:25689854   PMID:28811219   PMID:31138677   PMID:31330130   PMID:32325033   PMID:33378226   PMID:34321999   PMID:35803934  
PMID:36417873  


Genomics

Comparative Map Data
Tnrc6a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397122,630,324 - 122,794,519 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7122,723,108 - 122,794,519 (+)EnsemblGRCm39 Ensembl
GRCm387123,031,101 - 123,195,296 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7123,123,885 - 123,195,296 (+)EnsemblGRCm38mm10GRCm38
MGSCv377130,267,399 - 130,338,810 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367122,914,984 - 122,986,454 (+)NCBIMGSCv36mm8
Celera7123,004,629 - 123,075,878 (+)NCBICelera
Cytogenetic Map7F2- F3NCBI
cM Map767.42NCBI
TNRC6A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381624,610,205 - 24,826,218 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1624,610,209 - 24,827,632 (+)EnsemblGRCh38hg38GRCh38
GRCh371624,621,526 - 24,837,539 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361624,648,550 - 24,745,049 (+)NCBINCBI36Build 36hg18NCBI36
Celera1623,518,894 - 23,615,357 (+)NCBICelera
Cytogenetic Map16p12.1NCBI
HuRef1622,832,154 - 22,928,155 (+)NCBIHuRef
CHM1_11625,755,032 - 25,851,538 (+)NCBICHM1_1
T2T-CHM13v2.01624,887,133 - 25,103,177 (+)NCBIT2T-CHM13v2.0
Tnrc6a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81186,992,457 - 187,146,764 (+)NCBIGRCr8
mRatBN7.21177,561,898 - 177,715,669 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1177,646,030 - 177,715,660 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1185,982,679 - 186,051,718 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01193,168,669 - 193,237,707 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01185,846,128 - 185,915,335 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01192,991,584 - 193,146,403 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1193,076,430 - 193,146,394 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01200,079,394 - 200,206,235 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41181,982,994 - 182,053,510 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11182,122,897 - 182,191,066 (+)NCBI
Celera1175,335,300 - 175,404,345 (+)NCBICelera
Cytogenetic Map1q36NCBI
Tnrc6a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554933,090,088 - 3,243,731 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554933,057,035 - 3,243,668 (+)NCBIChiLan1.0ChiLan1.0
TNRC6A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21826,020,802 - 26,232,707 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11630,541,876 - 30,753,579 (+)NCBINHGRI_mPanPan1
PanPan1.11624,853,809 - 25,064,998 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1624,966,474 - 25,064,998 (+)Ensemblpanpan1.1panPan2
TNRC6A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1621,247,492 - 21,454,424 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl621,248,948 - 21,420,719 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha622,816,233 - 22,917,782 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0621,385,360 - 21,492,387 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl621,385,944 - 21,591,644 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1621,190,299 - 21,297,275 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0621,093,728 - 21,200,685 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0621,487,588 - 21,595,440 (-)NCBIUU_Cfam_GSD_1.0
Tnrc6a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344120,919,007 - 121,094,660 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365019,045,546 - 9,193,281 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365019,016,844 - 9,192,946 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNRC6A
(Sus scrofa - pig)
No map positions available.
TNRC6A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1522,341,159 - 22,553,822 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl522,453,931 - 22,553,843 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660687,201,098 - 7,416,576 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnrc6a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247829,608,245 - 9,807,237 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tnrc6a
5456 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:793
Count of miRNA genes:441
Interacting mature miRNAs:533
Transcripts:ENSMUST00000094053
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785049208124199223Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787249208126499172Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787249208126499172Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791482996125483156Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791482996125483156Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793391848127392041Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined799837716133837716Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7100750722134750843Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7100993261134993342Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102485219136485380Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105250663139250811Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105350008139350008Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7109707335143707335Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7109707335143707335Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7109707335143707335Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7112922733144995196Mouse
38501072Stsl7_mSalmonella typhimurium susceptibility locus 7 (mouse)7115699235128501724Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7116634089144995196Mouse
15092059Wogrme1_mweek one growth rate, maternal effect 1 (mouse)7117199227134101729Mouse
11059561Lmr21a_mleishmaniasis resistance 21a (mouse)7117750722127967336Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7118693381144398314Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119132573144995196Mouse
1558745Tsiq1_mT-cell secretion of IL-4 QTL 1 (mouse)Not determined7119485219125141349Mouse
1357613Bsbob2_mBSB obesity 2 (mouse)Not determined7122250663128819324Mouse
1301903Tlsm1_mthymic lymphoma susceptible 1 (mouse)Not determined7122250663135170901Mouse

Markers in Region
AW557223  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387123,194,801 - 123,194,898UniSTSGRCm38
MGSCv377130,338,315 - 130,338,412UniSTSGRCm37
Celera7123,075,383 - 123,075,480UniSTS
Cytogenetic Map7F3UniSTS
Whitehead/MRC_RH71266.98UniSTS
Tnrc6a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F3UniSTS
cM Map7 UniSTS
L17913  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387123,162,546 - 123,162,688UniSTSGRCm38
MGSCv377130,306,060 - 130,306,202UniSTSGRCm37
Celera7123,043,209 - 123,043,351UniSTS
Cytogenetic Map7F3UniSTS
Tnrc6a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F3UniSTS
cM Map7 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_144925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006507705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036153007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036153008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036153009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036153010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC138364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC141887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK020685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK129366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF020619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY720212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD802917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000094053   ⟹   ENSMUSP00000091595
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7122,723,404 - 122,794,519 (+)Ensembl
GRCm38.p6 Ensembl7123,124,181 - 123,195,296 (+)Ensembl
RefSeq Acc Id: ENSMUST00000205449
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7122,770,610 - 122,774,921 (+)Ensembl
GRCm38.p6 Ensembl7123,171,387 - 123,175,698 (+)Ensembl
RefSeq Acc Id: ENSMUST00000205514   ⟹   ENSMUSP00000145912
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7122,723,400 - 122,793,210 (+)Ensembl
GRCm38.p6 Ensembl7123,124,177 - 123,193,987 (+)Ensembl
RefSeq Acc Id: ENSMUST00000205732
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7122,772,081 - 122,773,420 (+)Ensembl
GRCm38.p6 Ensembl7123,172,858 - 123,174,197 (+)Ensembl
RefSeq Acc Id: ENSMUST00000205760   ⟹   ENSMUSP00000146266
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7122,769,854 - 122,793,201 (+)Ensembl
GRCm38.p6 Ensembl7123,170,631 - 123,193,978 (+)Ensembl
RefSeq Acc Id: ENSMUST00000205789
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7122,768,345 - 122,770,127 (+)Ensembl
GRCm38.p6 Ensembl7123,169,122 - 123,170,904 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206014   ⟹   ENSMUSP00000146300
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7122,773,438 - 122,779,844 (+)Ensembl
GRCm38.p6 Ensembl7123,174,215 - 123,180,621 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206126
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7122,779,144 - 122,792,953 (+)Ensembl
GRCm38.p6 Ensembl7123,179,921 - 123,193,730 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206458
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7122,723,108 - 122,761,886 (+)Ensembl
GRCm38.p6 Ensembl7123,123,885 - 123,162,663 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206888   ⟹   ENSMUSP00000145963
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7122,723,479 - 122,776,915 (+)Ensembl
GRCm38.p6 Ensembl7123,124,256 - 123,177,692 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206922
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7122,770,869 - 122,773,655 (+)Ensembl
GRCm38.p6 Ensembl7123,171,646 - 123,174,432 (+)Ensembl
RefSeq Acc Id: NM_144925   ⟹   NP_659174
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,723,108 - 122,794,519 (+)NCBI
GRCm387123,123,885 - 123,195,296 (+)NCBI
MGSCv377130,267,399 - 130,338,810 (+)RGD
Celera7123,004,629 - 123,075,878 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006507705   ⟹   XP_006507768
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,721,959 - 122,793,794 (+)NCBI
GRCm387123,122,736 - 123,195,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011241757   ⟹   XP_011240059
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,630,324 - 122,794,519 (+)NCBI
GRCm387123,031,101 - 123,195,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011241758   ⟹   XP_011240060
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,630,324 - 122,793,794 (+)NCBI
GRCm387123,031,101 - 123,195,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011241760   ⟹   XP_011240062
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,630,324 - 122,793,794 (+)NCBI
GRCm387123,031,101 - 123,195,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011241762   ⟹   XP_011240064
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,630,324 - 122,793,794 (+)NCBI
GRCm387123,031,101 - 123,195,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011241763   ⟹   XP_011240065
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,630,324 - 122,793,794 (+)NCBI
GRCm387123,031,101 - 123,195,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011241764   ⟹   XP_011240066
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,630,324 - 122,780,534 (+)NCBI
GRCm387123,031,101 - 123,181,312 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011241765   ⟹   XP_011240067
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,630,324 - 122,774,038 (+)NCBI
GRCm387123,031,101 - 123,176,704 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322201   ⟹   XP_017177690
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,721,959 - 122,793,794 (+)NCBI
GRCm387123,122,736 - 123,195,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322202   ⟹   XP_017177691
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,630,324 - 122,794,519 (+)NCBI
GRCm387123,031,101 - 123,195,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322203   ⟹   XP_017177692
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,630,324 - 122,793,794 (+)NCBI
GRCm387123,031,101 - 123,195,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322204   ⟹   XP_017177693
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,721,959 - 122,793,794 (+)NCBI
GRCm387123,122,736 - 123,195,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322205   ⟹   XP_017177694
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,721,959 - 122,793,794 (+)NCBI
GRCm387123,122,736 - 123,195,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322206   ⟹   XP_017177695
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,721,959 - 122,793,794 (+)NCBI
GRCm387123,122,736 - 123,195,296 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036153007   ⟹   XP_036008900
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,745,619 - 122,793,794 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036153008   ⟹   XP_036008901
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,630,324 - 122,793,794 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036153009   ⟹   XP_036008902
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,721,959 - 122,793,794 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036153010   ⟹   XP_036008903
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397122,723,407 - 122,793,794 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_659174 (Get FASTA)   NCBI Sequence Viewer  
  XP_006507768 (Get FASTA)   NCBI Sequence Viewer  
  XP_011240059 (Get FASTA)   NCBI Sequence Viewer  
  XP_011240060 (Get FASTA)   NCBI Sequence Viewer  
  XP_011240062 (Get FASTA)   NCBI Sequence Viewer  
  XP_011240064 (Get FASTA)   NCBI Sequence Viewer  
  XP_011240065 (Get FASTA)   NCBI Sequence Viewer  
  XP_011240066 (Get FASTA)   NCBI Sequence Viewer  
  XP_011240067 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177690 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177691 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177692 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177693 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177694 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177695 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008900 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008901 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008902 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008903 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH05741 (Get FASTA)   NCBI Sequence Viewer  
  AAH26849 (Get FASTA)   NCBI Sequence Viewer  
  BAC32030 (Get FASTA)   NCBI Sequence Viewer  
  BAC34334 (Get FASTA)   NCBI Sequence Viewer  
  BAC39039 (Get FASTA)   NCBI Sequence Viewer  
  BAC98176 (Get FASTA)   NCBI Sequence Viewer  
  BAE23657 (Get FASTA)   NCBI Sequence Viewer  
  BAE25197 (Get FASTA)   NCBI Sequence Viewer  
  BAE25198 (Get FASTA)   NCBI Sequence Viewer  
  BAE27849 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000091595
  ENSMUSP00000091595.6
  ENSMUSP00000145912.2
  ENSMUSP00000145963.2
  ENSMUSP00000146266
  ENSMUSP00000146266.2
  ENSMUSP00000146300.2
GenBank Protein Q3UHK8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_659174   ⟸   NM_144925
- UniProtKB: F6ZMJ4 (UniProtKB/Swiss-Prot),   Q3UHK8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006507768   ⟸   XM_006507705
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011240059   ⟸   XM_011241757
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011240062   ⟸   XM_011241760
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_011240064   ⟸   XM_011241762
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_011240060   ⟸   XM_011241758
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011240065   ⟸   XM_011241763
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_011240066   ⟸   XM_011241764
- Peptide Label: isoform X15
- Sequence:
RefSeq Acc Id: XP_011240067   ⟸   XM_011241765
- Peptide Label: isoform X16
- UniProtKB: Q05CE3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017177691   ⟸   XM_017322202
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017177692   ⟸   XM_017322203
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_017177693   ⟸   XM_017322204
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_017177690   ⟸   XM_017322201
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017177694   ⟸   XM_017322205
- Peptide Label: isoform X13
- UniProtKB: A0A0U1RQ65 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017177695   ⟸   XM_017322206
- Peptide Label: isoform X13
- UniProtKB: A0A0U1RQ65 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000146300   ⟸   ENSMUST00000206014
RefSeq Acc Id: ENSMUSP00000145963   ⟸   ENSMUST00000206888
RefSeq Acc Id: ENSMUSP00000146266   ⟸   ENSMUST00000205760
RefSeq Acc Id: ENSMUSP00000145912   ⟸   ENSMUST00000205514
RefSeq Acc Id: ENSMUSP00000091595   ⟸   ENSMUST00000094053
RefSeq Acc Id: XP_036008901   ⟸   XM_036153008
- Peptide Label: isoform X12
RefSeq Acc Id: XP_036008902   ⟸   XM_036153009
- Peptide Label: isoform X14
- UniProtKB: A0A0U1RQ65 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036008903   ⟸   XM_036153010
- Peptide Label: isoform X14
- UniProtKB: A0A0U1RQ65 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036008900   ⟸   XM_036153007
- Peptide Label: isoform X8
Protein Domains
Argonaute hook   RRM   TNRC6 PABC binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3UHK8-F1-model_v2 AlphaFold Q3UHK8 1-1896 view protein structure

Promoters
RGD ID:8665479
Promoter ID:EPDNEW_M10771
Type:initiation region
Name:Tnrc6a_1
Description:Mus musculus trinucleotide repeat containing 6a , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10772  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387123,123,886 - 123,123,946EPDNEW
RGD ID:8665481
Promoter ID:EPDNEW_M10772
Type:initiation region
Name:Tnrc6a_2
Description:Mus musculus trinucleotide repeat containing 6a , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10771  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387123,124,178 - 123,124,238EPDNEW
RGD ID:6842224
Promoter ID:MM_KWN:52601
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_144925,   UC009JPB.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367130,267,331 - 130,267,831 (+)MPROMDB
RGD ID:6842226
Promoter ID:MM_KWN:52602
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung
Transcripts:UC009JPD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367130,312,471 - 130,315,632 (+)MPROMDB
RGD ID:6842227
Promoter ID:MM_KWN:52603
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Liver,   Lung
Transcripts:UC009JPE.1,   UC009JPF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367130,322,331 - 130,324,102 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2385292 AgrOrtholog
Ensembl Genes ENSMUSG00000052707 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000094053 ENTREZGENE
  ENSMUST00000094053.7 UniProtKB/Swiss-Prot
  ENSMUST00000205514.2 UniProtKB/TrEMBL
  ENSMUST00000205760 ENTREZGENE
  ENSMUST00000205760.2 UniProtKB/TrEMBL
  ENSMUST00000206014.2 UniProtKB/TrEMBL
  ENSMUST00000206888.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Argonaute_hook_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  TNRC6_PABC-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNRC6A_RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:233833 UniProtKB/Swiss-Prot
MGD MGI:2385292 ENTREZGENE
NCBI Gene 233833 ENTREZGENE
PANTHER PTHR13020:SF28 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ago_hook UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
  TNRC6-PABC_bdg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tnrc6a PhenoGen
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0U1RPB4_MOUSE UniProtKB/TrEMBL
  A0A0U1RPF5_MOUSE UniProtKB/TrEMBL
  A0A0U1RQ65 ENTREZGENE, UniProtKB/TrEMBL
  A0A0U1RQ94_MOUSE UniProtKB/TrEMBL
  F6ZMJ4 ENTREZGENE
  Q05CE3 ENTREZGENE, UniProtKB/TrEMBL
  Q3UHK8 ENTREZGENE
  Q3UQ45_MOUSE UniProtKB/TrEMBL
  Q3UUG8_MOUSE UniProtKB/TrEMBL
  Q6ZPQ4_MOUSE UniProtKB/TrEMBL
  Q8BNF0_MOUSE UniProtKB/TrEMBL
  Q8BWM2_MOUSE UniProtKB/TrEMBL
  Q8BXM6_MOUSE UniProtKB/TrEMBL
  Q99JR3_MOUSE UniProtKB/TrEMBL
  TNR6A_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary F6ZMJ4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-22 Tnrc6a  trinucleotide repeat containing 6a  Tnrc6  trinucleotide repeat containing 6  Data merged from RGD:1316361 737654 PROVISIONAL