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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of response to endoplasmic reticulum stress
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Accession:GO:1905898 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress.
Synonyms:exact_synonym: positive regulation of ER stress response;   positive regulation of cellular response to endoplasmic reticulum stress;   positive regulation of response to ER stress;   up regulation of ER stress response;   up regulation of cellular response to endoplasmic reticulum stress;   up regulation of response to ER stress;   up regulation of response to endoplasmic reticulum stress;   upregulation of ER stress response;   upregulation of cellular response to endoplasmic reticulum stress;   upregulation of response to ER stress;   upregulation of response to endoplasmic reticulum stress
 narrow_synonym: activation of ER stress response;   activation of cellular response to endoplasmic reticulum stress;   activation of response to ER stress;   activation of response to endoplasmic reticulum stress


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positive regulation of response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO (PMID:21803450) RGD PMID:21803450 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Fcgr2b Fc gamma receptor 2B involved_in IMP
ISO		 PMID:23921129
(MGI:5514474|PMID:23921129)		 RGD PMID:23921129 PMID:23921129 MGI:5514474, RGD:12910988 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6 activating transcription factor 6 involved_in ISO
IEA		 (PMID:9837962)
GO_REF:0000107		 RGD
Ensembl		 PMID:9837962 GO_REF:0000107 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO		 GO_REF:0000024
(MGI:5648772|PMID:26015568), (MGI:5796067|PMID:26949185)		 UniProt
RGD		 PMID:26015568 PMID:26949185 GO_REF:0000024 MGI:5648772 MGI:5796067 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:1913418 (PMID:22240901) RGD PMID:22240901 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA		 (PMID:14676213)
GO_REF:0000033
UniProtKB:O55033 (MGI:5613475|PMID:16835242)		 RGD
GO_Central		 PMID:14676213 PMID:16835242 GO_REF:0000033 MGI:5613475 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA		 UniProtKB:Q99M51 (MGI:5613475|PMID:16835242)
GO_REF:0000033		 RGD
GO_Central		 PMID:16835242 GO_REF:0000033 MGI:5613475 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
IEA		 (MGI:5619464|PMID:21216966)
GO_REF:0000107		 RGD
Ensembl		 PMID:21216966 GO_REF:0000107 MGI:5619464 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Rnf183 ring finger protein 183 involved_in ISO
IBA		 (PMID:29507230)
GO_REF:0000033		 RGD
GO_Central		 PMID:29507230 GO_REF:0000033 NCBI chr 5:75,877,111...75,886,253
Ensembl chr 5:75,876,003...75,886,191 		JBrowse link
G Serinc3 serine incorporator 3 acts_upstream_of_or_within ISO (PMID:12486168) RGD PMID:12486168 NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (MGI:5607229|PMID:20955178)
GO_REF:0000107		 RGD
Ensembl		 PMID:20955178 GO_REF:0000107 MGI:5607229 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Spop speckle type BTB/POZ protein acts_upstream_of_or_within ISO MGI:102851 (PMID:20811152) RGD PMID:20811152 NCBI chr10:80,358,121...80,438,983
Ensembl chr10:80,358,124...80,483,955 		JBrowse link
positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:16645094) RGD PMID:16645094 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in ISO
ISS		 (PMID:16645094)
GO_REF:0000024		 RGD
UniProt		 PMID:16645094 GO_REF:0000024 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:16645094), (PMID:28128204) RGD PMID:16645094 PMID:28128204 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO
IEA
ISS		 (PMID:20348923)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20348923 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA		 (PMID:16645094)
GO_REF:0000107		 RGD
Ensembl		 PMID:16645094 GO_REF:0000107 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn3 ataxin 3 involved_in ISO (PMID:17000876) RGD PMID:17000876 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902 		JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISO
IEA		 (PMID:24424410)
GO_REF:0000107		 RGD
Ensembl		 PMID:24424410 GO_REF:0000107 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Bcap31 B-cell receptor-associated protein 31 involved_in ISO UniProtKB:Q9BUN8 (PMID:18555783) RGD PMID:18555783 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506 		JBrowse link
G Cav1 caveolin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24089527)		 Ensembl
RGD		 PMID:24089527 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO (PMID:18307982), (PMID:22045699) RGD PMID:18307982 PMID:22045699 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Rnf185 ring finger protein 185 involved_in ISO
IEA
ISS		 (PMID:27485036)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:27485036 GO_REF:0000024 GO_REF:0000107 NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864 		JBrowse link
G Rnft1 ring finger protein, transmembrane 1 involved_in ISO
IBA		 (PMID:27485036)
GO_REF:0000033		 RGD
GO_Central		 PMID:27485036 GO_REF:0000033 NCBI chr10:71,310,052...71,322,507
Ensembl chr10:71,310,104...71,323,778 		JBrowse link
G Rnft2 ring finger protein, transmembrane 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:38,329,217...38,387,303
Ensembl chr12:38,329,269...38,387,290 		JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA
ISO		 GO_REF:0000107
(PMID:23246001)		 Ensembl
RGD		 PMID:23246001 GO_REF:0000107 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:26265139) RGD PMID:26265139 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Tmem259 transmembrane protein 259 involved_in ISO
IBA		 (MGI:5648655|PMID:25977983)
GO_REF:0000033		 RGD
GO_Central		 PMID:25977983 GO_REF:0000033 MGI:5648655 NCBI chr 7:9,724,196...9,730,932
Ensembl chr 7:9,722,485...9,730,932 		JBrowse link
G Tmem67 transmembrane protein 67 IMP RGD PMID:19815549 RGD:8554391 NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334 		JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 involved_in ISO (PMID:29932915) RGD PMID:29932915 NCBI chr 6:88,960,691...88,971,744
Ensembl chr 6:88,960,695...88,971,301 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18307982)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18307982 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18307982) RGD PMID:18307982 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505 		JBrowse link
G Usp13 ubiquitin specific peptidase 13 involved_in ISO (PMID:24424410) RGD PMID:24424410 NCBI chr 2:115,576,912...115,689,153
Ensembl chr 2:115,577,091...115,686,222 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (PMID:19911006) RGD PMID:19911006 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member involved_in ISO (PMID:23220234) RGD PMID:23220234 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371 		JBrowse link
G Tmem33 transmembrane protein 33 involved_in ISO
ISS		 (PMID:26268696)
GO_REF:0000024		 RGD
UniProt		 PMID:26268696 GO_REF:0000024 NCBI chr14:40,888,485...40,910,715
Ensembl chr14:40,885,712...40,910,715 		JBrowse link
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member involved_in ISO (PMID:23220234) RGD PMID:23220234 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO		 GO_REF:0000024
(MGI:5648772|PMID:26015568)		 UniProt
RGD		 PMID:26015568 GO_REF:0000024 MGI:5648772 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
IEA		 (MGI:5619464|PMID:21216966)
GO_REF:0000107		 RGD
Ensembl		 PMID:21216966 GO_REF:0000107 MGI:5619464 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Tmem33 transmembrane protein 33 involved_in ISO
ISS		 (PMID:26268696)
GO_REF:0000024		 RGD
UniProt		 PMID:26268696 GO_REF:0000024 NCBI chr14:40,888,485...40,910,715
Ensembl chr14:40,885,712...40,910,715 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18195
      positive regulation of cellular process 6086
        positive regulation of response to endoplasmic reticulum stress 36
          positive regulation of ERAD pathway 17
          positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 9
          positive regulation of endoplasmic reticulum unfolded protein response + 10
Path 2
Term Annotations click to browse term
  biological_process 19692
    biological regulation 13305
      regulation of biological process 12902
        regulation of response to stimulus 4169
          regulation of response to stress 1430
            regulation of cellular response to stress 510
              regulation of response to endoplasmic reticulum stress 87
                positive regulation of response to endoplasmic reticulum stress 36
                  positive regulation of ERAD pathway 17
                  positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 9
                  positive regulation of endoplasmic reticulum unfolded protein response + 10
paths to the root