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ONTOLOGY REPORT - ANNOTATIONS

Term:retinal ganglion cell axon guidance
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Accession:GO:0031290 term browser browse the term
Definition:The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
Synonyms:exact_synonym: retinal ganglion cell axon pathfinding


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retinal ganglion cell axon guidance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alcam activated leukocyte cell adhesion molecule involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B acts_upstream_of_or_within ISO MGI:2158497 (PMID:12654290) RGD PMID:12654290 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368 		JBrowse link
G Efna5 ephrin A5 acts_upstream_of_or_within ISO (PMID:15996548) RGD PMID:15996548 NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413 		JBrowse link
G Epha7 Eph receptor A7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3583808 (PMID:15996548)		 Ensembl
RGD		 PMID:15996548 GO_REF:0000107 NCBI chr 5:42,975,353...43,128,703
Ensembl chr 5:42,975,405...43,127,112 		JBrowse link
G Ephb1 Eph receptor B1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:12971893)		 UniProt
RGD		 PMID:12971893 GO_REF:0000024 NCBI chr 8:111,386,432...111,823,759
Ensembl chr 8:102,507,549...102,944,839 		JBrowse link
G Ephb2 Eph receptor B2 acts_upstream_of_or_within ISO (PMID:12971893) RGD PMID:12971893 NCBI chr 5:154,179,065...154,360,459
Ensembl chr 5:148,897,246...149,077,059 		JBrowse link
G Ephb3 Eph receptor B3 acts_upstream_of_or_within ISO (PMID:12971893) RGD PMID:12971893 NCBI chr11:93,345,098...93,363,775
Ensembl chr11:79,840,668...79,859,370 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3790243 (PMID:18434421)		 Ensembl
RGD		 PMID:18434421 GO_REF:0000107 NCBI chr 2:49,813,618...49,823,442
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Isl2 ISL LIM homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3046260 (PMID:15537545)		 Ensembl
RGD		 PMID:15537545 GO_REF:0000107 NCBI chr 8:64,819,879...64,824,864
Ensembl chr 8:55,923,805...55,928,790 		JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO (PMID:29079753) RGD PMID:29079753 NCBI chr  X:8,379,569...8,404,019
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Nrcam neuronal cell adhesion molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2387976 (PMID:16701205)		 Ensembl
RGD		 PMID:16701205 GO_REF:0000107 NCBI chr 6:67,129,723...67,425,510
Ensembl chr 6:61,329,863...61,702,992 		JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (PMID:21658587) RGD PMID:21658587 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Pou4f2 POU class 4 homeobox 2 acts_upstream_of_or_within ISO MGI:102523|MGI:2429634 (PMID:11807038), (PMID:18434421) RGD PMID:11807038 PMID:18434421 NCBI chr19:46,390,958...46,394,599
Ensembl chr19:29,486,686...29,490,327 		JBrowse link
G Pou4f3 POU class 4 homeobox 3 acts_upstream_of_or_within ISO MGI:102524 (PMID:11807038) RGD PMID:11807038 NCBI chr18:34,641,191...34,643,783
Ensembl chr18:34,390,205...34,392,797 		JBrowse link
G Ptprm protein tyrosine phosphatase, receptor type, M involved_in ISO
ISS		 (PMID:15080886)
GO_REF:0000024		 RGD
UniProt		 PMID:15080886 GO_REF:0000024 NCBI chr 9:114,086,380...114,791,000
Ensembl chr 9:106,639,573...107,343,698 		JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO (PMID:19782674) RGD PMID:19782674 NCBI chr11:26,015,919...27,583,750
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
G Rpl24 ribosomal protein L24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856685 (PMID:9331275)		 Ensembl
RGD		 PMID:9331275 GO_REF:0000107 NCBI chr11:58,122,997...58,128,405
Ensembl chr11:44,653,937...44,659,370 		JBrowse link
G Sema4f semaphorin 4F acts_upstream_of_or_within IDA PMID:10051670 MGI PMID:10051670 RGD:69991 NCBI chr 4:115,411,411...115,437,721
Ensembl chr 4:115,411,417...115,437,721 		JBrowse link
G Slit1 slit guidance ligand 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1315205|MGI:2179459 (PMID:11804570), (PMID:16828733), (PMID:16885222)		 Ensembl
RGD		 PMID:11804570 PMID:16828733 PMID:16885222 GO_REF:0000107 NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:10864954), (PMID:19498462)
MGI:1315203|MGI:2179460 (PMID:11804570), (PMID:16828733), (PMID:16885222)
GO_REF:0000107		 RGD
Ensembl		 PMID:10864954 PMID:11804570 PMID:16828733 PMID:16885222 PMID:19498462 GO_REF:0000107 NCBI chr14:66,829,661...67,168,517
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in
NOT|involved_in		 ISO (PMID:21658587) RGD PMID:21658587 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Zic2 Zic family member 2 involved_in ISO (PMID:13678579) RGD PMID:13678579 NCBI chr15:105,982,711...105,988,167
Ensembl chr15:99,576,697...99,581,522 		JBrowse link
negative regulation of retinal ganglion cell axon guidance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slit2 slit guidance ligand 2 involved_in ISO
IEA		 (PMID:17062560)
GO_REF:0000107		 RGD
Ensembl		 PMID:17062560 GO_REF:0000107 NCBI chr14:66,829,661...67,168,517
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
positive regulation of retinal ganglion cell axon guidance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh7 atonal bHLH transcription factor 7 involved_in ISO (PMID:33712461) RGD PMID:33712461 NCBI chr20:25,529,528...25,529,977
Ensembl chr20:25,530,826...25,531,275 		JBrowse link
regulation of retinal ganglion cell axon guidance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou4f2 POU class 4 homeobox 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11163266)		 UniProt
RGD		 PMID:11163266 GO_REF:0000024 NCBI chr19:46,390,958...46,394,599
Ensembl chr19:29,486,686...29,490,327 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    developmental process 7109
      anatomical structure morphogenesis 3006
        cell morphogenesis 1143
          cell morphogenesis involved in neuron differentiation 696
            axonogenesis 515
              axon guidance 248
                retinal ganglion cell axon guidance 23
                  negative regulation of retinal ganglion cell axon guidance 1
                  positive regulation of retinal ganglion cell axon guidance 1
                  regulation of retinal ganglion cell axon guidance + 3
Path 2
Term Annotations click to browse term
  biological_process 20536
    developmental process 7109
      anatomical structure development 6611
        multicellular organism development 5330
          system development 4612
            nervous system development 2862
              neurogenesis 2117
                generation of neurons 1811
                  neuron differentiation 1732
                    neuron development 1420
                      neuron projection development 1245
                        neuron projection morphogenesis 761
                          neuron projection guidance 249
                            axon guidance 248
                              retinal ganglion cell axon guidance 23
                                negative regulation of retinal ganglion cell axon guidance 1
                                positive regulation of retinal ganglion cell axon guidance 1
                                regulation of retinal ganglion cell axon guidance + 3
paths to the root