Bmpr1b (bone morphogenetic protein receptor type 1B) - Rat Genome Database

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Gene: Bmpr1b (bone morphogenetic protein receptor type 1B) Rattus norvegicus
Analyze
Symbol: Bmpr1b
Name: bone morphogenetic protein receptor type 1B
RGD ID: 1595863
Description: Predicted to enable several functions, including ATP binding activity; enzyme activator activity; and transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in several processes, including ovarian cumulus expansion; positive regulation of bone mineralization; and positive regulation of osteoblast differentiation. Predicted to act upstream of or within several processes, including cartilage development; neuron differentiation; and positive regulation of extrinsic apoptotic signaling pathway via death domain receptors. Located in dendrite and neuronal cell body. Human ortholog(s) of this gene implicated in acromesomelic dysplasia-3; brachydactyly type A1D; brachydactyly type A2; and osteochondrodysplasia. Orthologous to human BMPR1B (bone morphogenetic protein receptor type 1B); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; cytokine mediated signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Bmpr1b_mapped; bone morphogenetic protein binding serine/threonine kinase receptor; bone morphogenetic protein receptor type-1B; bone morphogenetic protein receptor, type 1B; bone morphogenetic protein receptor, type 1B (mapped); bone morphogenetic protein receptor, type IB; CFK-43a; hypothetical protein LOC684964; LOC684964
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22230,538,252 - 230,871,077 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2230,541,558 - 230,871,368 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2238,293,725 - 238,626,557 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02236,186,745 - 236,519,586 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02231,051,401 - 231,384,251 (-)NCBIRnor_WKY
Rnor_6.02247,392,195 - 247,662,026 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2247,403,920 - 247,446,882 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02265,932,565 - 266,183,671 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42239,727,569 - 239,767,802 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2222,597,416 - 222,630,407 (-)NCBICelera
Cytogenetic Map2q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Chromosomal localization of three human genes encoding bone morphogenetic protein receptors. Astrom AK, etal., Mamm Genome 1999 Mar;10(3):299-302.
2. A homozygous BMPR1B mutation causes a new subtype of acromesomelic chondrodysplasia with genital anomalies. Demirhan O, etal., J Med Genet. 2005 Apr;42(4):314-7.
3. Bone morphogenetic protein signalling in heritable versus idiopathic pulmonary hypertension. Dewachter L, etal., Eur Respir J. 2009 Nov;34(5):1100-10. Epub 2009 Mar 26.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Basal expression of bone morphogenetic protein receptor is reduced in mild asthma. Kariyawasam HH, etal., Am J Respir Crit Care Med. 2008 May 15;177(10):1074-81. Epub 2008 Feb 21.
6. Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2. Lehmann K, etal., Proc Natl Acad Sci U S A 2003 Oct 14;100(21):12277-82. Epub 2003 Oct 01.
7. Bone morphogenetic protein receptor expressions in the adult rat brain. Miyagi M, etal., Neuroscience. 2011 Mar 10;176:93-109. Epub 2010 Dec 23.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Wine-Lee L, etal., Development 2004 Nov;131(21):5393-403. Epub 2004 Oct 6.
Additional References at PubMed
PMID:10631181   PMID:11376112   PMID:11416163   PMID:12065756   PMID:12117821   PMID:12151307   PMID:12477932   PMID:12654290   PMID:15673568   PMID:16049014   PMID:16604073   PMID:18326817  
PMID:18363966   PMID:18436533   PMID:19669850   PMID:24098149   PMID:24129431   PMID:25501208  


Genomics

Comparative Map Data
Bmpr1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22230,538,252 - 230,871,077 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2230,541,558 - 230,871,368 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2238,293,725 - 238,626,557 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02236,186,745 - 236,519,586 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02231,051,401 - 231,384,251 (-)NCBIRnor_WKY
Rnor_6.02247,392,195 - 247,662,026 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2247,403,920 - 247,446,882 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02265,932,565 - 266,183,671 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42239,727,569 - 239,767,802 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2222,597,416 - 222,630,407 (-)NCBICelera
Cytogenetic Map2q44NCBI
BMPR1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38494,757,955 - 95,158,450 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl494,757,955 - 95,158,448 (+)EnsemblGRCh38hg38GRCh38
GRCh37495,679,106 - 96,079,601 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36495,898,151 - 96,295,099 (+)NCBINCBI36Build 36hg18NCBI36
Build 34496,036,305 - 96,433,254NCBI
Celera493,094,009 - 93,376,257 (+)NCBICelera
Cytogenetic Map4q22.3NCBI
HuRef491,416,328 - 91,816,286 (+)NCBIHuRef
CHM1_1495,656,120 - 96,056,666 (+)NCBICHM1_1
T2T-CHM13v2.0498,073,083 - 98,473,123 (+)NCBIT2T-CHM13v2.0
Bmpr1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393141,540,230 - 141,875,335 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3141,542,897 - 141,875,186 (-)EnsemblGRCm39 Ensembl
GRCm383141,837,135 - 142,169,585 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3141,837,136 - 142,169,425 (-)EnsemblGRCm38mm10GRCm38
MGSCv373141,500,100 - 141,645,215 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363141,774,523 - 141,919,638 (-)NCBIMGSCv36mm8
Celera3148,249,912 - 148,405,204 (-)NCBICelera
Cytogenetic Map3H1NCBI
Bmpr1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554055,700,162 - 5,787,957 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554055,408,171 - 5,784,930 (+)NCBIChiLan1.0ChiLan1.0
BMPR1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1497,912,541 - 98,194,890 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl498,088,072 - 98,195,848 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0487,125,911 - 87,523,084 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
BMPR1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13217,761,555 - 17,978,056 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3217,870,904 - 18,016,444 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3223,966,621 - 24,007,268 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03217,942,009 - 18,159,433 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3217,896,212 - 18,157,297 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13218,086,524 - 18,127,395 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03217,908,347 - 17,949,143 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03221,943,473 - 21,984,364 (-)NCBIUU_Cfam_GSD_1.0
Bmpr1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530123,751,702 - 24,000,364 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366872,503,777 - 2,597,522 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049366872,346,601 - 2,595,283 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMPR1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8124,536,653 - 124,759,406 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18124,536,648 - 125,035,841 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28133,742,891 - 134,240,938 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BMPR1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366603721,372,638 - 21,773,741 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bmpr1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475722,955,666 - 23,142,499 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475722,697,639 - 23,142,209 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bmpr1b
1931 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:27
Count of miRNA genes:27
Interacting mature miRNAs:27
Transcripts:ENSRNOT00000021963
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2215377404237938339Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2218414747240841241Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
9587428Epfw6Epididymal fat weight QTL 67.470.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)2223389739249053267Rat
7411555Bw132Body weight QTL 1320.001body mass (VT:0001259)body weight gain (CMO:0000420)2223389739249053267Rat
631563Hcuc3Hepatic copper content QTL 33.87liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)2229059610249053267Rat

Markers in Region
AI385617  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22230,541,685 - 230,541,823 (+)MAPPERmRatBN7.2
Rnor_6.02247,403,950 - 247,404,087NCBIRnor6.0
Rnor_5.02265,932,694 - 265,932,831UniSTSRnor5.0
RGSC_v3.42239,727,698 - 239,727,835UniSTSRGSC3.4
Celera2222,597,545 - 222,597,682UniSTS
Cytogenetic Map2q44UniSTS
Z23143  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22230,541,635 - 230,541,787 (+)MAPPERmRatBN7.2
Rnor_6.02247,403,900 - 247,404,051NCBIRnor6.0
Rnor_5.02265,932,644 - 265,932,795UniSTSRnor5.0
RGSC_v3.42239,727,648 - 239,727,799UniSTSRGSC3.4
Celera2222,597,495 - 222,597,646UniSTS
Cytogenetic Map2q44UniSTS
MARC_8975-8976:1025019065:3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22230,560,856 - 230,561,683 (+)MAPPERmRatBN7.2
Rnor_6.02247,423,681 - 247,424,507NCBIRnor6.0
Rnor_5.02265,951,731 - 265,952,557UniSTSRnor5.0
Celera2222,616,680 - 222,617,506UniSTS
Cytogenetic Map2q44UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 15 31 10
Low 1 27 15 6 9 6 8 11 59 4 31 11 8
Below cutoff 14 23 16 10 16

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001024259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001836470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC092609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FB745995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000021963   ⟹   ENSRNOP00000021963
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2230,541,558 - 230,871,090 (-)Ensembl
Rnor_6.0 Ensembl2247,403,920 - 247,446,882 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109499   ⟹   ENSRNOP00000077524
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2230,541,558 - 230,871,368 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110878   ⟹   ENSRNOP00000084253
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2230,541,558 - 230,588,377 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114929   ⟹   ENSRNOP00000086028
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2230,541,558 - 230,632,451 (-)Ensembl
RefSeq Acc Id: NM_001024259   ⟹   NP_001019430
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22230,541,557 - 230,574,599 (-)NCBI
Rnor_6.02247,403,821 - 247,437,419 (-)NCBI
Rnor_5.02265,932,565 - 266,183,671 (-)NCBI
RGSC_v3.42239,727,569 - 239,767,802 (-)RGD
Celera2222,597,416 - 222,630,407 (-)RGD
Sequence:
RefSeq Acc Id: XM_006233400   ⟹   XP_006233462
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22230,538,252 - 230,685,059 (-)NCBI
Rnor_6.02247,403,824 - 247,553,577 (-)NCBI
Rnor_5.02265,932,565 - 266,183,671 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006233401   ⟹   XP_006233463
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22230,538,252 - 230,632,439 (-)NCBI
Rnor_6.02247,403,824 - 247,495,304 (-)NCBI
Rnor_5.02265,932,565 - 266,183,671 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017590943   ⟹   XP_017446432
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22230,538,252 - 230,583,845 (-)NCBI
Rnor_6.02247,403,824 - 247,446,663 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102478   ⟹   XP_038958406
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22230,538,252 - 230,685,058 (-)NCBI
RefSeq Acc Id: XM_039102479   ⟹   XP_038958407
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22230,538,252 - 230,871,076 (-)NCBI
RefSeq Acc Id: XM_039102480   ⟹   XP_038958408
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22230,538,252 - 230,788,918 (-)NCBI
RefSeq Acc Id: XM_039102481   ⟹   XP_038958409
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22230,538,252 - 230,871,077 (-)NCBI
RefSeq Acc Id: XM_039102482   ⟹   XP_038958410
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22230,538,252 - 230,628,555 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001019430   ⟸   NM_001024259
- UniProtKB: A0A8I5ZJI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233463   ⟸   XM_006233401
- Peptide Label: isoform X1
- UniProtKB: M0R3J4 (UniProtKB/TrEMBL),   A0A8I5ZJI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233462   ⟸   XM_006233400
- Peptide Label: isoform X1
- UniProtKB: M0R3J4 (UniProtKB/TrEMBL),   A0A8I5ZJI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446432   ⟸   XM_017590943
- Peptide Label: isoform X2
- UniProtKB: M0R3J4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000021963   ⟸   ENSRNOT00000021963
RefSeq Acc Id: XP_038958409   ⟸   XM_039102481
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZJI2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958407   ⟸   XM_039102479
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038958408   ⟸   XM_039102480
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZJI2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958406   ⟸   XM_039102478
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZJI2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958410   ⟸   XM_039102482
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZJI2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000084253   ⟸   ENSRNOT00000110878
RefSeq Acc Id: ENSRNOP00000086028   ⟸   ENSRNOT00000114929
RefSeq Acc Id: ENSRNOP00000077524   ⟸   ENSRNOT00000109499
Protein Domains
GS   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R3J4-F1-model_v2 AlphaFold M0R3J4 1-502 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1595863 AgrOrtholog
BioCyc Gene G2FUF-51002 BioCyc
Ensembl Genes ENSRNOG00000016289 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000021963 ENTREZGENE
  ENSRNOP00000021963.7 UniProtKB/TrEMBL
  ENSRNOP00000077524 ENTREZGENE
  ENSRNOP00000077524.1 UniProtKB/TrEMBL
  ENSRNOP00000084253 ENTREZGENE
  ENSRNOP00000084253.1 UniProtKB/TrEMBL
  ENSRNOP00000086028.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021963 ENTREZGENE
  ENSRNOT00000021963.8 UniProtKB/TrEMBL
  ENSRNOT00000109499 ENTREZGENE
  ENSRNOT00000109499.1 UniProtKB/TrEMBL
  ENSRNOT00000110878 ENTREZGENE
  ENSRNOT00000110878.1 UniProtKB/TrEMBL
  ENSRNOT00000114929.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.60.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7310757 IMAGE-MGC_LOAD
InterPro Activin_recp UniProtKB/TrEMBL
  GS_dom UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Ser/Thr_prot_kinase_AS UniProtKB/TrEMBL
  Snake_toxin-like_sf UniProtKB/TrEMBL
  TGFB_receptor UniProtKB/TrEMBL
KEGG Report rno:310914 UniProtKB/TrEMBL
MGC_CLONE MGC:109250 IMAGE-MGC_LOAD
NCBI Gene 310914 ENTREZGENE
PANTHER PTHR23255 UniProtKB/TrEMBL
Pfam Activin_recp UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/TrEMBL
  TGF_beta_GS UniProtKB/TrEMBL
PhenoGen Bmpr1b PhenoGen
PRINTS ACTIVIN2R UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  PS51256 UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
  SM00467 UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
  SSF57302 UniProtKB/TrEMBL
UniProt A0A8I5ZJI2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZXN2_RAT UniProtKB/TrEMBL
  A0A8I6A0G0_RAT UniProtKB/TrEMBL
  M0R3J4 ENTREZGENE, UniProtKB/TrEMBL
  Q569A5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-03 Bmpr1b  bone morphogenetic protein receptor type 1B  Bmpr1b  bone morphogenetic protein receptor, type IB  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 Bmpr1b  bone morphogenetic protein receptor, type IB  LOC684964  hypothetical protein LOC684964  Data Merged 737654 PROVISIONAL
2008-09-26 Bmpr1b  bone morphogenetic protein receptor, type IB  Bmpr1b  bone morphogenetic protein receptor, type 1B (mapped)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC684964  hypothetical protein LOC684964  LOC687473  hypothetical protein LOC687473  Data Merged 1643240 APPROVED
2007-03-16 Bmpr1b  bone morphogenetic protein receptor, type 1B (mapped)  Bmpr1b_mapped  bone morphogenetic protein receptor, type 1B (mapped)  Data Merged 737654 PROVISIONAL
2006-11-20 Bmpr1b  bone morphogenetic protein receptor, type 1B (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC684964  hypothetical protein LOC684964      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC687473  hypothetical protein LOC687473      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Bmpr1b_mapped  bone morphogenetic protein receptor, type 1B (mapped)  Bmpr1b  bone morphogenetic protein receptor, type 1B  Symbol and Name updated 1556543 APPROVED
2005-01-20 Bmpr1b  bone morphogenetic protein receptor, type 1B      Name updated 1299863 APPROVED
2002-08-07 Bmpr1b        Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference