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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of blood coagulation
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Accession:GO:0030195 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
Synonyms:exact_synonym: down regulation of blood coagulation;   downregulation of blood coagulation
 narrow_synonym: inhibition of blood coagulation


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negative regulation of blood coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADTRP androgen dependent TFPI regulating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:11,300,186...11,362,893
Ensembl chr35:11,300,887...11,362,101 		JBrowse link
G ANXA5 annexin A5 ISO RGD PMID:20684318 RGD:7241850 NCBI chr19:18,419,936...18,450,088
Ensembl chr19:18,407,587...18,570,378 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G APOH apolipoprotein H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185 		JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G KNG1 kininogen 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:19,288,629...19,318,096
Ensembl chr34:19,287,109...19,318,081 		JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:9616155)
(PMID:9788960)		 RGD
MGI
GO_Central		 PMID:1440533 PMID:9616155 PMID:9788960 GO_REF:0000033 RGD:11100042 NCBI chr19:23,173,626...23,183,634
Ensembl chr19:23,173,635...23,183,563 		JBrowse link
G SERPINE2 serpin family E member 2 involved_in ISO (PMID:17379830) BHF-UCL PMID:17379830 RGD:8553298 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228 		JBrowse link
G TFPI tissue factor pathway inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:29,457,131...29,546,455
Ensembl chr36:29,459,371...29,511,310 		JBrowse link
G THBD thrombomodulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:599,773...601,649
Ensembl chr24:599,773...601,649 		JBrowse link
G TSPAN8 tetraspanin 8 ISO RGD PMID:9531564 RGD:634231 NCBI chr10:12,786,824...12,818,257
Ensembl chr10:12,786,867...12,818,088 		JBrowse link
fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14702107) Ensembl
MGI		 PMID:14702107 GO_REF:0000107 NCBI chr30:25,176,845...25,210,244
Ensembl chr30:25,115,842...25,218,281 		JBrowse link
G CPB2 carboxypeptidase B2 involved_in ISO
IEA		 RGD
InterPro		 PMID:11848438 GO_REF:0000002 RGD:632532 NCBI chr22:5,074,805...5,126,635
Ensembl chr22:5,074,816...5,126,170 		JBrowse link
G F12 coagulation factor XII involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G FETUB fetuin B involved_in IEA UniProt GO_REF:0000043 NCBI chr34:19,259,362...19,273,030
Ensembl chr34:19,259,357...19,273,030 		JBrowse link
G FGA fibrinogen alpha chain involved_in ISO (PMID:16846481) UniProt PMID:16846481 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGB fibrinogen beta chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250 		JBrowse link
G FGG fibrinogen gamma chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964 		JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:12855810) UniProt PMID:12855810 NCBI chr 5:31,681,605...31,683,261 JBrowse link
G HRG histidine rich glycoprotein involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15869579) UniProt
MGI		 PMID:15869579 GO_REF:0000043 NCBI chr34:19,276,487...19,286,540
Ensembl chr34:19,276,549...19,286,537 		JBrowse link
G PLAU plasminogen activator, urokinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9733098) Ensembl
MGI		 PMID:9733098 GO_REF:0000107 NCBI chr 4:24,329,139...24,333,893
Ensembl chr 4:24,328,925...24,334,851 		JBrowse link
G PLG plasminogen involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G PROS1 protein S involved_in IEA UniProt GO_REF:0000043 NCBI chr33:1,628,074...1,691,441
Ensembl chr33:1,628,105...1,692,058 		JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOH apolipoprotein H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185 		JBrowse link
G CPB2 carboxypeptidase B2 ISO RGD PMID:17002650 RGD:2313647 NCBI chr22:5,074,805...5,126,635
Ensembl chr22:5,074,816...5,126,170 		JBrowse link
G HRG histidine rich glycoprotein acts_upstream_of_or_within ISO (PMID:15869579) MGI PMID:15869579 NCBI chr34:19,276,487...19,286,540
Ensembl chr34:19,276,549...19,286,537 		JBrowse link
G PLG plasminogen involved_in ISO (PMID:14726399) BHF-UCL PMID:14726399 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G SERPINE1 serpin family E member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301 		JBrowse link
G SERPINF2 serpin family F member 2 involved_in ISO
IEA		 RGD
Ensembl
InterPro		 PMID:6506034 GO_REF:0000002 GO_REF:0000107 RGD:1625541 NCBI chr 9:45,876,076...45,883,777
Ensembl chr 9:45,877,495...45,883,036 		JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915 		JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G C1QTNF1 C1q and TNF related 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:2,401,369...2,405,595
Ensembl chr 9:2,402,945...2,404,053 		JBrowse link
G PDGFA platelet derived growth factor subunit A involved_in ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chr 6:16,271,082...16,293,246
Ensembl chr 6:16,270,104...16,292,396 		JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278 		JBrowse link
G SERPINE2 serpin family E member 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:19855083) MGI
BHF-UCL		 PMID:19855083 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228 		JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19218546) Ensembl
MGI		 PMID:19218546 GO_REF:0000107 NCBI chr 5:73,769,462...73,907,024
Ensembl chr 5:73,772,114...73,905,264 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,026,193...32,038,698
Ensembl chr 5:31,882,501...32,038,119 		JBrowse link
G C1QTNF1 C1q and TNF related 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:2,401,369...2,405,595
Ensembl chr 9:2,402,945...2,404,053 		JBrowse link
G CD9 CD9 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,742,539...38,754,984
Ensembl chr27:38,742,963...38,774,576 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (PMID:19008452) UniProt PMID:19008452 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830 		JBrowse link
G PRKCD protein kinase C delta involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:35,732,974...36,932,744
Ensembl chr26:35,737,242...36,932,729 		JBrowse link
G SERPINE2 serpin family E member 2 involved_in ISO (PMID:19855083) BHF-UCL PMID:19855083 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228 		JBrowse link
G SH2B3 SH2B adaptor protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:9,033,851...9,073,095
Ensembl chr26:9,005,281...9,070,204 		JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:27,541,407...27,556,058
Ensembl chr 8:27,541,460...27,554,681 		JBrowse link
G UBASH3B ubiquitin associated and SH3 domain containing B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20585042) Ensembl
MGI		 PMID:20585042 GO_REF:0000107 NCBI chr 5:11,496,254...11,614,769
Ensembl chr 5:11,500,669...11,614,675 		JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G F12 coagulation factor XII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025 		JBrowse link
G KLKB1 kallikrein B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292 		JBrowse link
G PLG plasminogen involved_in ISO (PMID:26667841), (PMID:6438154) AgBase PMID:6438154 PMID:26667841 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOH apolipoprotein H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17101
    negative regulation of biological process 5550
      negative regulation of hemostasis 42
        negative regulation of blood coagulation 41
          fibrinolysis + 19
          negative regulation of blood coagulation, common pathway 0
          negative regulation of blood coagulation, extrinsic pathway 0
          negative regulation of blood coagulation, intrinsic pathway 0
          negative regulation of platelet activation + 15
          positive regulation of fibrinolysis 4
Path 2
Term Annotations click to browse term
  biological_process 17101
    biological regulation 11805
      regulation of biological process 11454
        regulation of response to stimulus 3982
          regulation of response to stress 1414
            regulation of response to wounding 182
              regulation of wound healing 133
                regulation of blood coagulation 60
                  negative regulation of blood coagulation 41
                    fibrinolysis + 19
                    negative regulation of blood coagulation, common pathway 0
                    negative regulation of blood coagulation, extrinsic pathway 0
                    negative regulation of blood coagulation, intrinsic pathway 0
                    negative regulation of platelet activation + 15
                    positive regulation of fibrinolysis 4
paths to the root