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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of platelet activation
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Accession:GO:0010544 term browser browse the term
Definition:Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.


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negative regulation of platelet activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E ISO
IEA
(PMID:8995232)
GO_REF:0000107
RGD
Ensembl
PMID:8995232 GO_REF:0000107 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G C1qtnf1 C1q and TNF related 1 ISO (PMID:16195328) RGD PMID:16195328 NCBI chr10:107,455,845...107,477,160
Ensembl chr10:107,455,845...107,477,162
JBrowse link
G Gp5 glycoprotein V (platelet) ISO MGI:MGI:2652408 (MGI:MGI:1347746|PMID:10557321), (MGI:MGI:2137180|PMID:11435305) RGD PMID:10557321, PMID:11435305 MGI:MGI:1347746, MGI:MGI:2137180 NCBI chr11:73,015,380...73,017,570 JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO
ISS
IEA
(PMID:2538439)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:2538439 GO_REF:0000024, GO_REF:0000107 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO
ISS
IEA
(PMID:2538439)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:2538439 GO_REF:0000024, GO_REF:0000107 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO
IEA
ISS
(PMID:8188664)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:8188664 GO_REF:0000024, GO_REF:0000107 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Serpine2 serpin family E member 2 ISO MGI:MGI:2387774 (MGI:MGI:4418017|PMID:19855083) RGD PMID:19855083 MGI:MGI:4418017 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:12742000 RGD:10047059 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 ISO (MGI:MGI:3848389|PMID:19218546)
(PMID:19218546)
RGD PMID:19218546 MGI:MGI:3848389 NCBI chr19:46,005,055...46,167,912
Ensembl chr19:46,005,277...46,101,250
JBrowse link
G Adrb2 adrenoceptor beta 2 IMP RGD PMID:6140045 RGD:8548522 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type ISO
ISS
(MGI:MGI:1202206|PMID:9501222)
GO_REF:0000024
RGD
UniProt
PMID:9501222 GO_REF:0000024, MGI:MGI:1202206 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G C1qtnf1 C1q and TNF related 1 IEA
ISO
GO_REF:0000107
(PMID:16195328)
Ensembl
RGD
PMID:16195328 GO_REF:0000107 NCBI chr10:107,455,845...107,477,160
Ensembl chr10:107,455,845...107,477,162
JBrowse link
G Cd9 CD9 molecule ISO
ISS
(PMID:18541721)
GO_REF:0000024
RGD
UniProt
PMID:18541721 GO_REF:0000024 NCBI chr 4:157,977,163...158,010,091
Ensembl chr 4:157,977,162...158,010,166
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 ISO
ISS
(MGI:MGI:3835235|PMID:19008452)
GO_REF:0000024
RGD
UniProt
PMID:19008452 GO_REF:0000024, MGI:MGI:3835235 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Fgg fibrinogen gamma chain IDA RGD PMID:22985603 RGD:11352706 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Prkcd protein kinase C, delta IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:3813784|PMID:16940418)
Ensembl
UniProt
RGD
PMID:16940418 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3813784 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 ISO (PMID:16990611) RGD PMID:16990611 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:20303752 RGD:10043327 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Serpine2 serpin family E member 2 ISO
IEA
(MGI:MGI:4418017|PMID:19855083)
GO_REF:0000107
RGD
Ensembl
PMID:19855083 GO_REF:0000107, MGI:MGI:4418017 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISO
IEA
UniProtKB:P35951 (MGI:MGI:5905608|PMID:27430239)
GO_REF:0000107
RGD
Ensembl
PMID:27430239 GO_REF:0000107, MGI:MGI:5905608 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B ISO (MGI:MGI:4838721|PMID:20585042) RGD PMID:20585042 MGI:MGI:4838721 NCBI chr 8:45,224,053...45,375,450
Ensembl chr 8:45,223,992...45,375,435
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    negative regulation of biological process 5696
      negative regulation of cellular process 5144
        negative regulation of cell activation 220
          negative regulation of platelet activation 19
            negative regulation of platelet aggregation + 14
Path 2
Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological process 13071
        regulation of response to stimulus 4096
          regulation of response to stress 1401
            regulation of response to wounding 189
              regulation of wound healing 147
                regulation of blood coagulation 82
                  negative regulation of blood coagulation 48
                    negative regulation of platelet activation 19
                      negative regulation of platelet aggregation + 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.