PRKG1 (protein kinase cGMP-dependent 1) - Rat Genome Database

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Gene: PRKG1 (protein kinase cGMP-dependent 1) Canis lupus familiaris
Analyze
Symbol: PRKG1
Name: protein kinase cGMP-dependent 1
RGD ID: 12267764
Description: ENCODES a protein that exhibits calcium channel regulator activity (ortholog); cGMP binding (ortholog); cGMP-dependent protein kinase activity (ortholog); INVOLVED IN brain development (ortholog); cell growth involved in cardiac muscle cell development (ortholog); cerebellum development (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ASSOCIATED WITH allergic rhinitis (ortholog); amphetamine abuse (ortholog); connective tissue disease (ortholog); FOUND IN acrosomal vesicle (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: cGMP-dependent protein kinase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12635,732,974 - 36,932,744 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2635,737,242 - 36,932,729 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2635,620,229 - 36,818,502 (-)NCBI
ROS_Cfam_1.02637,271,288 - 38,465,630 (-)NCBI
UMICH_Zoey_3.12635,169,158 - 36,367,548 (-)NCBI
UNSW_CanFamBas_1.02634,756,074 - 35,955,695 (-)NCBI
UU_Cfam_GSD_1.02635,996,645 - 37,196,072 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
PRKG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12635,732,974 - 36,932,744 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2635,737,242 - 36,932,729 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2635,620,229 - 36,818,502 (-)NCBI
ROS_Cfam_1.02637,271,288 - 38,465,630 (-)NCBI
UMICH_Zoey_3.12635,169,158 - 36,367,548 (-)NCBI
UNSW_CanFamBas_1.02634,756,074 - 35,955,695 (-)NCBI
UU_Cfam_GSD_1.02635,996,645 - 37,196,072 (-)NCBI
PRKG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1050,990,888 - 52,298,423 (+)EnsemblGRCh38hg38GRCh38
GRCh381050,990,888 - 52,298,350 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371052,750,648 - 54,058,110 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361052,420,951 - 53,725,280 (+)NCBINCBI36hg18NCBI36
Build 341052,504,298 - 53,725,280NCBI
Celera1046,013,603 - 47,318,321 (+)NCBI
Cytogenetic Map10q11.23-q21.1NCBI
HuRef1046,729,527 - 48,036,312 (+)NCBIHuRef
CHM1_11053,032,644 - 54,339,928 (+)NCBICHM1_1
Prkg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391930,541,887 - 31,742,667 (-)NCBIGRCm39mm39
GRCm39 Ensembl1930,541,889 - 31,742,433 (-)Ensembl
GRCm381930,564,487 - 31,765,268 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1930,564,489 - 31,765,033 (-)EnsemblGRCm38mm10GRCm38
MGSCv371930,642,041 - 31,839,523 (-)NCBIGRCm37mm9NCBIm37
MGSCv361930,633,548 - 31,831,030 (-)NCBImm8
Celera1931,351,778 - 32,553,439 (-)NCBICelera
Cytogenetic Map19C1NCBI
Prkg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21228,409,883 - 229,638,794 (-)NCBImRatBN7.2
Rnor_6.01248,982,039 - 250,300,952 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01256,221,067 - 257,537,289 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41234,420,597 - 235,765,375 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11235,515,049 - 235,845,833 (-)NCBI
Celera1225,545,145 - 226,760,176 (-)NCBICelera
Cytogenetic Map1q52NCBI
Prkg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554256,176,432 - 7,331,446 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554256,176,335 - 7,335,867 (+)NCBIChiLan1.0ChiLan1.0
PRKG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11049,778,821 - 51,069,314 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1049,779,211 - 51,064,882 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01047,642,312 - 48,935,188 (+)NCBIMhudiblu_PPA_v0panPan3
Prkg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721375,309,475 - 76,469,932 (-)NCBI
SpeTri2.0NW_004936787330,390 - 1,491,994 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1497,560,785 - 98,793,318 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11497,558,531 - 98,793,080 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214106,256,149 - 107,028,245 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.214107,499,623 - 107,663,552 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRKG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1978,858,269 - 80,188,163 (-)NCBI
Vero_WHO_p1.0NW_02366604839,812,502 - 40,750,048 (-)NCBI
Prkg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479111,334,146 - 12,656,480 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 2 6
Low 1 5 22 6 4 6 6 12 8 10 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022410516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038512536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038512537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038512538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038512539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038512540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038576026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038576027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038576028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038576029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038576030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038640236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038640237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038640238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038640239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038640240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_846904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000044295   ⟹   ENSCAFP00000035869
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2635,737,242 - 36,932,729 (-)Ensembl
RefSeq Acc Id: XM_022410516   ⟹   XP_022266224
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12635,732,974 - 36,840,241 (-)NCBI
Dog10K_Boxer_Tasha2635,620,229 - 36,726,911 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038437664   ⟹   XP_038293592
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02637,271,288 - 38,381,796 (-)NCBI
RefSeq Acc Id: XM_038437665   ⟹   XP_038293593
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02637,271,288 - 38,465,630 (-)NCBI
RefSeq Acc Id: XM_038437666   ⟹   XP_038293594
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02637,271,288 - 38,373,941 (-)NCBI
RefSeq Acc Id: XM_038437667   ⟹   XP_038293595
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02637,271,288 - 37,625,249 (-)NCBI
RefSeq Acc Id: XM_038437668   ⟹   XP_038293596
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02637,271,288 - 37,421,794 (-)NCBI
RefSeq Acc Id: XM_038459215   ⟹   XP_038315143
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2635,620,229 - 36,734,759 (-)NCBI
RefSeq Acc Id: XM_038459216   ⟹   XP_038315144
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2635,620,229 - 35,974,068 (-)NCBI
RefSeq Acc Id: XM_038459217   ⟹   XP_038315145
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2635,620,229 - 35,770,947 (-)NCBI
RefSeq Acc Id: XM_038512536   ⟹   XP_038368464
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12635,169,158 - 36,283,839 (-)NCBI
RefSeq Acc Id: XM_038512537   ⟹   XP_038368465
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12635,169,158 - 36,367,548 (-)NCBI
RefSeq Acc Id: XM_038512538   ⟹   XP_038368466
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12635,169,158 - 36,276,005 (-)NCBI
RefSeq Acc Id: XM_038512539   ⟹   XP_038368467
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12635,169,158 - 35,522,330 (-)NCBI
RefSeq Acc Id: XM_038512540   ⟹   XP_038368468
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12635,169,158 - 35,319,588 (-)NCBI
RefSeq Acc Id: XM_038576026   ⟹   XP_038431954
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02635,996,645 - 37,112,245 (-)NCBI
RefSeq Acc Id: XM_038576027   ⟹   XP_038431955
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02635,996,645 - 37,196,072 (-)NCBI
RefSeq Acc Id: XM_038576028   ⟹   XP_038431956
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02635,996,645 - 37,104,369 (-)NCBI
RefSeq Acc Id: XM_038576029   ⟹   XP_038431957
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02635,996,645 - 36,350,825 (-)NCBI
RefSeq Acc Id: XM_038576030   ⟹   XP_038431958
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02635,996,645 - 36,147,597 (-)NCBI
RefSeq Acc Id: XM_038640236   ⟹   XP_038496164
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02634,756,074 - 35,872,195 (-)NCBI
RefSeq Acc Id: XM_038640237   ⟹   XP_038496165
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02634,756,074 - 35,955,695 (-)NCBI
RefSeq Acc Id: XM_038640238   ⟹   XP_038496166
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02634,756,074 - 35,864,352 (-)NCBI
RefSeq Acc Id: XM_038640239   ⟹   XP_038496167
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02634,756,074 - 35,110,362 (-)NCBI
RefSeq Acc Id: XM_038640240   ⟹   XP_038496168
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02634,756,074 - 34,906,897 (-)NCBI
RefSeq Acc Id: XM_846904   ⟹   XP_851997
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12635,732,974 - 36,932,744 (-)NCBI
Dog10K_Boxer_Tasha2635,620,229 - 36,818,502 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_851997   ⟸   XM_846904
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_022266224   ⟸   XM_022410516
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCAFP00000035869   ⟸   ENSCAFT00000044295
RefSeq Acc Id: XP_038368465   ⟸   XM_038512537
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038368464   ⟸   XM_038512536
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038368466   ⟸   XM_038512538
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038368467   ⟸   XM_038512539
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038368468   ⟸   XM_038512540
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038496165   ⟸   XM_038640237
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038496164   ⟸   XM_038640236
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038496166   ⟸   XM_038640238
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038496167   ⟸   XM_038640239
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038496168   ⟸   XM_038640240
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038293593   ⟸   XM_038437665
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038293592   ⟸   XM_038437664
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038293594   ⟸   XM_038437666
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038293595   ⟸   XM_038437667
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038293596   ⟸   XM_038437668
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038315143   ⟸   XM_038459215
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038315144   ⟸   XM_038459216
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038315145   ⟸   XM_038459217
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038431955   ⟸   XM_038576027
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038431954   ⟸   XM_038576026
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038431956   ⟸   XM_038576028
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038431957   ⟸   XM_038576029
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038431958   ⟸   XM_038576030
- Peptide Label: isoform X5


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031979 Ensembl, ENTREZGENE
Ensembl Protein ENSCAFP00000035869 ENTREZGENE
NCBI Gene PRKG1 ENTREZGENE
VGNC ID VGNC:49948 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-07-17 PRKG1  protein kinase cGMP-dependent 1    protein kinase, cGMP-dependent, type I  Symbol and/or name change 5135510 APPROVED