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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of blood coagulation
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Accession:GO:0030195 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
Synonyms:exact_synonym: down regulation of blood coagulation;   downregulation of blood coagulation
 narrow_synonym: inhibition of blood coagulation



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negative regulation of blood coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADTRP androgen dependent TFPI regulating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:11,300,186...11,362,893
Ensembl chr35:11,300,887...11,362,101
JBrowse link
G ANXA5 annexin A5 ISO RGD PMID:20684318 RGD:7241850 NCBI chr19:18,419,936...18,450,088
Ensembl chr19:18,407,587...18,570,378
JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G APOH apolipoprotein H involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185
JBrowse link
G CD34 CD34 molecule involved_in ISS
IEA
UniProt
UniProt
Ensembl
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:6,734,363...6,747,991
Ensembl chr 7:6,734,363...6,748,581
JBrowse link
G KNG1 kininogen 1 involved_in ISO (PMID:11970955) UniProt PMID:11970955 NCBI chr34:19,288,629...19,318,096
Ensembl chr34:19,287,109...19,318,081
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:1306904|PMID:9788960)
(MGI:1261704|PMID:9616155)
GO_Central
GO_Central
MGI
RGD
PMID:1440533 PMID:9616155 PMID:9788960 PMID:21873635 MGI:1261704 MGI:1306904 RGD:11100042 NCBI chr19:23,173,626...23,183,634
Ensembl chr19:23,173,635...23,183,563
JBrowse link
G SERPINE2 serpin family E member 2 involved_in ISO (PMID:17379830) BHF-UCL PMID:17379830 RGD:8553298 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228
JBrowse link
G TFPI tissue factor pathway inhibitor involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr36:29,457,131...29,546,455
Ensembl chr36:29,459,371...29,511,310
JBrowse link
G THBD thrombomodulin involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr24:599,773...601,649
Ensembl chr24:599,773...601,649
JBrowse link
G TSPAN8 tetraspanin 8 ISO RGD PMID:9531564 RGD:634231 NCBI chr10:12,786,824...12,818,257
Ensembl chr10:12,786,867...12,818,088
JBrowse link
fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3027337|PMID:14702107) MGI
Ensembl
PMID:14702107 GO_REF:0000107 MGI:3027337 NCBI chr30:25,176,845...25,210,244
Ensembl chr30:25,115,842...25,218,281
JBrowse link
G CPB2 carboxypeptidase B2 involved_in IBA
IEA
ISO
(PMID:21873635) GO_Central
InterPro
InterPro
RGD
PMID:11848438 PMID:21873635 GO_REF:0000002 RGD:632532 NCBI chr22:5,074,805...5,126,635
Ensembl chr22:5,074,816...5,126,170
JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459
JBrowse link
G FGA fibrinogen alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975
JBrowse link
G FGB fibrinogen beta chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250
JBrowse link
G FGG fibrinogen gamma chain involved_in ISO (PMID:16846481) UniProt PMID:16846481 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964
JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:31,681,605...31,683,261 JBrowse link
G HRG histidine rich glycoprotein acts_upstream_of ISO (MGI:3789419|PMID:15869579) MGI PMID:15869579 MGI:3789419 NCBI chr34:19,276,487...19,286,540
Ensembl chr34:19,276,549...19,286,537
JBrowse link
G PLAU plasminogen activator, urokinase acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:1277054|PMID:9733098)
(PMID:21873635)
MGI
GO_Central
PMID:9733098 PMID:21873635 MGI:1277054 NCBI chr 4:24,329,139...24,333,893
Ensembl chr 4:24,328,925...24,334,851
JBrowse link
G PLG plasminogen involved_in IEA UniProt
UniProt
GO_REF:0000043 GO_REF:0000104 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260
JBrowse link
G PROS1 protein S involved_in IEA UniProt GO_REF:0000043 NCBI chr33:1,628,074...1,691,441
Ensembl chr33:1,628,105...1,692,058
JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOH apolipoprotein H involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185
JBrowse link
G CPB2 carboxypeptidase B2 ISO RGD PMID:17002650 RGD:2313647 NCBI chr22:5,074,805...5,126,635
Ensembl chr22:5,074,816...5,126,170
JBrowse link
G HRG histidine rich glycoprotein acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:3789419|PMID:15869579)
(PMID:21873635)
MGI
GO_Central
PMID:15869579 PMID:21873635 MGI:3789419 NCBI chr34:19,276,487...19,286,540
Ensembl chr34:19,276,549...19,286,537
JBrowse link
G PLG plasminogen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260
JBrowse link
G SERPINE1 serpin family E member 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301
JBrowse link
G SERPINF2 serpin family F member 2 involved_in IEA
ISO
Ensembl
InterPro
RGD
PMID:6506034 GO_REF:0000002 GO_REF:0000107 RGD:1625541 NCBI chr 9:45,876,076...45,883,777
Ensembl chr 9:45,877,495...45,883,036
JBrowse link
G THBS1 thrombospondin 1 involved_in ISO (PMID:6438154) BHF-UCL PMID:6438154 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915
JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G C1QTNF1 C1q and TNF related 1 involved_in ISO (PMID:16195328) UniProt PMID:16195328 NCBI chr 9:2,401,369...2,405,595
Ensembl chr 9:2,402,945...2,404,053
JBrowse link
G PDGFA platelet derived growth factor subunit A involved_in ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chr 6:16,271,082...16,293,246
Ensembl chr 6:16,270,104...16,292,396
JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278
JBrowse link
G SERPINE2 serpin family E member 2 acts_upstream_of_or_within ISO (MGI:4418017|PMID:19855083) MGI PMID:19855083 MGI:4418017 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228
JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:12742000 RGD:10047059 NCBI chr 6:33,385,779...33,471,348
Ensembl chr 6:33,376,996...33,471,326
JBrowse link
G ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 acts_upstream_of_or_within ISO (MGI:3848389|PMID:19218546)
(PMID:19218546)
MGI PMID:19218546 MGI:3848389 NCBI chr 5:73,769,462...73,907,024
Ensembl chr 5:73,772,114...73,905,264
JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:6140045 RGD:8548522 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,026,193...32,038,698
Ensembl chr 5:31,882,501...32,038,119
JBrowse link
G C1QTNF1 C1q and TNF related 1 involved_in ISO (PMID:16195328) UniProt PMID:16195328 NCBI chr 9:2,401,369...2,405,595
Ensembl chr 9:2,402,945...2,404,053
JBrowse link
G CD9 CD9 molecule involved_in ISO (PMID:18541721) UniProt PMID:18541721 NCBI chr27:38,742,539...38,754,984
Ensembl chr27:38,742,963...38,774,576
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (MGI:3835235|PMID:19008452) UniProt PMID:19008452 MGI:3835235 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830
JBrowse link
G FGG fibrinogen gamma chain ISO RGD PMID:22985603 RGD:11352706 NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964
JBrowse link
G PRKCD protein kinase C delta involved_in ISS
IEA
UniProt
UniProt
Ensembl
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:35,732,974...36,932,744
Ensembl chr26:35,737,242...36,932,729
JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:20303752 RGD:10043327 NCBI chr 6:74,932,789...74,986,573 JBrowse link
G SERPINE2 serpin family E member 2 involved_in ISO (MGI:4418017|PMID:19855083) BHF-UCL PMID:19855083 MGI:4418017 NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228
JBrowse link
G SH2B3 SH2B adaptor protein 3 involved_in ISO (MGI:5905608|PMID:27430239) BHF-UCL PMID:27430239 MGI:5905608 NCBI chr26:9,033,851...9,073,095
Ensembl chr26:9,005,281...9,070,204
JBrowse link
G UBASH3B ubiquitin associated and SH3 domain containing B acts_upstream_of_or_within ISO (MGI:4838721|PMID:20585042) MGI PMID:20585042 MGI:4838721 NCBI chr 5:11,496,254...11,614,769
Ensembl chr 5:11,500,669...11,614,675
JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr16:44,469,609...44,492,833
Ensembl chr16:44,469,632...44,540,292
JBrowse link
G F12 coagulation factor XII involved_in ISO (PMID:89876) BHF-UCL PMID:89876 NCBI chr 4:35,950,642...35,968,137
Ensembl chr 4:35,950,695...35,998,025
JBrowse link
G KLKB1 kallikrein B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292
JBrowse link
G PLG plasminogen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260
JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOH apolipoprotein H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16445
    negative regulation of biological process 5668
      negative regulation of hemostasis 44
        negative regulation of blood coagulation 43
          fibrinolysis + 18
          negative regulation of blood coagulation in another organism + 0
          negative regulation of blood coagulation, common pathway 0
          negative regulation of blood coagulation, extrinsic pathway 0
          negative regulation of blood coagulation, intrinsic pathway 0
          negative regulation of platelet activation + 18
          positive regulation of fibrinolysis 4
Path 2
Term Annotations click to browse term
  biological_process 16445
    biological regulation 12002
      regulation of biological process 11362
        regulation of response to stimulus 3923
          regulation of response to stress 1395
            regulation of response to wounding 180
              regulation of wound healing 138
                regulation of blood coagulation 63
                  negative regulation of blood coagulation 43
                    fibrinolysis + 18
                    negative regulation of blood coagulation in another organism + 0
                    negative regulation of blood coagulation, common pathway 0
                    negative regulation of blood coagulation, extrinsic pathway 0
                    negative regulation of blood coagulation, intrinsic pathway 0
                    negative regulation of platelet activation + 18
                    positive regulation of fibrinolysis 4
paths to the root