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ONTOLOGY REPORT - ANNOTATIONS


Term:fibrinolysis
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Accession:GO:0042730 term browser browse the term
Definition:A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin.
Synonyms:xref: Wikipedia:Fibrinolysis


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fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 acts_upstream_of_or_within ISO MGI:3028929 (MGI:3027337|PMID:14702107) RGD PMID:14702107 MGI:3027337 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Cpb2 carboxypeptidase B2 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:11848438, PMID:21873635, PMID:21873635 RGD:632532, RGD:13792537, RGD:13792537 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760
JBrowse link
G F12 coagulation factor XII involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G F2 coagulation factor II involved_in IEA
ISO
GO_REF:0000107
(PMID:12855810)
Ensembl
RGD
PMID:12855810 GO_REF:0000107 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IEA
IBA
(PMID:16846481)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:16846481, PMID:21873635, PMID:21873635 GO_REF:0000107, RGD:13792537, RGD:13792537 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:12855810) RGD PMID:12855810 NCBI chr10:57,260,680...57,263,546
Ensembl chr10:57,260,680...57,263,546
JBrowse link
G Hrg histidine-rich glycoprotein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952
JBrowse link
G Klkb1 kallikrein B1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr11:81,621,283...81,639,952 JBrowse link
G Plau plasminogen activator, urokinase acts_upstream_of_or_within
involved_in
IEA
ISO
IBA
GO_REF:0000107
(MGI:1277054|PMID:9733098)
PMID:21873635
Ensembl
RGD
PMID:9733098, PMID:21873635, PMID:21873635 GO_REF:0000107 MGI:1277054, RGD:13792537, RGD:13792537 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Plg plasminogen involved_in IEA
ISO
GO_REF:0000104
(PMID:14688145), (PMID:17307854), (PMID:22025510)
UniProt
RGD
PMID:14688145 PMID:17307854 PMID:22025510 GO_REF:0000104 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Pros1 protein S involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:1,206,648...1,288,140
Ensembl chr 7:1,206,648...1,288,134
JBrowse link
G Serping1 serpin family G member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO
IEA
(PMID:14726399)
GO_REF:0000107
RGD
Ensembl
PMID:14726399 GO_REF:0000107 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938
JBrowse link
G Cpb2 carboxypeptidase B2 IDA RGD PMID:17002650 RGD:2313647 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760
JBrowse link
G Hrg histidine-rich glycoprotein acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:3789962 (MGI:3789419|PMID:15869579)
PMID:21873635
RGD PMID:15869579, PMID:21873635, PMID:21873635 MGI:3789419, RGD:13792537, RGD:13792537 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr11:81,621,283...81,639,952 JBrowse link
G Plg plasminogen involved_in ISO (PMID:14726399) RGD PMID:14726399 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA
(PMID:2503541)
GO_REF:0000107
RGD
Ensembl
PMID:2503541 GO_REF:0000107 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpinf2 serpin family F member 2 involved_in IMP
ISO
(PMID:134998) RGD PMID:134998, PMID:6506034 RGD:1625541 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:50,179,458...50,201,644
Ensembl chr16:50,179,458...50,201,698
JBrowse link
G F12 coagulation factor XII involved_in ISO
IEA
(PMID:89876)
GO_REF:0000107
RGD
Ensembl
PMID:89876 GO_REF:0000107 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G Klkb1 kallikrein B1 involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458
JBrowse link
G Plg plasminogen involved_in ISO (PMID:26667841), (PMID:6438154) RGD PMID:6438154 PMID:26667841 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 TAS RGD PMID:11739291 RGD:1578383 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Apoh apolipoprotein H involved_in ISO (PMID:16480936) RGD PMID:16480936 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    negative regulation of biological process 5713
      negative regulation of hemostasis 49
        negative regulation of blood coagulation 48
          fibrinolysis 20
            negative regulation of fibrinolysis 8
            positive regulation of fibrinolysis 4
            regulation of fibrinolysis + 12
Path 2
Term Annotations click to browse term
  biological_process 20082
    biological regulation 13906
      regulation of biological process 13141
        regulation of response to stimulus 3981
          regulation of response to stress 1296
            regulation of response to wounding 174
              regulation of wound healing 131
                regulation of blood coagulation 66
                  negative regulation of blood coagulation 48
                    fibrinolysis 20
                      negative regulation of fibrinolysis 8
                      positive regulation of fibrinolysis 4
                      regulation of fibrinolysis + 12
paths to the root