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ONTOLOGY REPORT - ANNOTATIONS


Term:protein dephosphorylation
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Accession:GO:0006470 term browser browse the term
Definition:The process of removing one or more phosphoric residues from a protein.
Synonyms:exact_synonym: protein amino acid dephosphorylation



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protein dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP1 dual specificity phosphatase 1 ISO RGD PMID:12435803 RGD:633811 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960
JBrowse link
G DUSP12 dual specificity phosphatase 12 ISO increases glucokinase activity by direct dephosphorylation RGD PMID:10913113 RGD:68242 NCBI chr 1:137,161,774...137,169,503
Ensembl chr 1:140,959,867...140,968,821
JBrowse link
G DUSP4 dual specificity phosphatase 4 ISO RGD PMID:12435803 RGD:633811 NCBI chr 8:28,623,777...28,641,432
Ensembl chr 8:25,819,989...25,834,332
JBrowse link
G ILKAP ILK associated serine/threonine phosphatase ISO RGD PMID:9857069 RGD:632254 NCBI chr2B:125,403,220...125,436,614
Ensembl chr2B:244,253,970...244,278,317
JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 ISO RGD PMID:20089132 PMID:20819118 RGD:5131540 RGD:8693633 NCBI chr18:56,084,851...56,338,551 JBrowse link
G PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 ISO RGD PMID:20089132 RGD:5131540 NCBI chr16:53,287,549...53,366,113
Ensembl chr16:71,481,605...71,562,793
JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F ISO RGD PMID:10456318 RGD:7241145 NCBI chr22:4,039,032...4,072,165
Ensembl chr22:20,520,022...20,553,128
JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha ISO RGD PMID:7720853 RGD:2304267 NCBI chr11:62,756,659...62,760,369
Ensembl chr11:66,068,007...66,071,611
JBrowse link
G PPP1CB protein phosphatase 1 catalytic subunit beta ISO RGD PMID:7720853 RGD:2304267 NCBI chr2A:28,758,176...28,809,561
Ensembl chr2A:28,862,083...28,889,401
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:16519540 PMID:18586681 RGD:1582610 RGD:8693384 NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786
JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta ISO RGD PMID:16519540 RGD:1582610 NCBI chr 8:30,099,605...30,126,917
Ensembl chr 8:27,288,263...27,302,606
JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO RGD PMID:1322410 PMID:12135494 RGD:727532 RGD:729536 NCBI chr 4:93,447,095...93,770,339
Ensembl chr 4:104,113,520...104,435,394
JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta ISO RGD PMID:12135494 RGD:729536 NCBI chr10:69,984,241...70,043,352
Ensembl chr10:72,443,051...72,501,752
JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha ISO RGD PMID:12135494 RGD:729536 NCBI chr2A:68,227,282...68,300,482 JBrowse link
G PPP5C protein phosphatase 5 catalytic subunit ISO RGD PMID:8077208 PMID:16892053 RGD:68293 RGD:8694079 NCBI chr19:43,329,680...43,373,282
Ensembl chr19:51,865,317...51,909,027
JBrowse link
G PPP6C protein phosphatase 6 catalytic subunit ISO RGD PMID:8077208 RGD:68293 NCBI chr 9:96,267,918...96,311,159
Ensembl chr 9:124,783,173...124,825,877
JBrowse link
G PTEN phosphatase and tensin homolog ISO RGD PMID:22609523 RGD:12801498 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO RGD PMID:7711057 PMID:17563729 RGD:2289367 RGD:2293185 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO RGD PMID:7711057 PMID:15272025 RGD:1581313 RGD:2293185 NCBI chr12:110,016,364...110,107,462
Ensembl chr12:113,435,669...113,503,762
JBrowse link
G PTPRF protein tyrosine phosphatase receptor type F ISO insulin receptor, EGF receptor RGD PMID:7711057 PMID:8068021 RGD:2293185 RGD:69951 NCBI chr 1:42,878,344...42,923,539
Ensembl chr 1:44,220,991...44,297,647
JBrowse link
G PTPRZ1 protein tyrosine phosphatase receptor type Z1 ISO RGD PMID:11381105 PMID:17646177 RGD:9589125 RGD:9590121 NCBI chr 7:113,882,557...114,073,283
Ensembl chr 7:126,569,630...126,758,155
JBrowse link
negative regulation of myosin-light-chain-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MPRIP myosin phosphatase Rho interacting protein ISO RGD PMID:17661354 RGD:9685557 NCBI chr17:34,101,451...34,251,475
Ensembl chr17:39,040,719...39,182,578
JBrowse link
negative regulation of peptidyl-serine dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP1R16B protein phosphatase 1 regulatory subunit 16B involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:35,130,114...35,248,031
Ensembl chr20:36,237,535...36,354,329
JBrowse link
G SWAP70 switching B cell complex subunit SWAP70 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:9,797,024...9,883,400
Ensembl chr11:9,526,752...9,614,422
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:1,332,004...1,387,120
Ensembl chr17:1,229,080...1,285,470
JBrowse link
negative regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPIA peptidylprolyl isomerase A ISO RGD PMID:19832699 RGD:7247324 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545
JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B ISO RGD PMID:10585469 PMID:12016225 RGD:625568 RGD:9999389 NCBI chr17:44,224,007...44,240,906
Ensembl chr17:49,098,089...49,126,932
JBrowse link
G RGN regucalcin ISO RGD PMID:10922512 RGD:9590172 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881
JBrowse link
negative regulation of protein dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP1 A-kinase anchoring protein 1 ISO NFATc3 RGD PMID:19358331 RGD:2312604 NCBI chr17:51,162,993...51,199,202
Ensembl chr17:56,023,381...56,058,744
JBrowse link
G ARPP19 cAMP regulated phosphoprotein 19 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:31,488,156...31,510,404
Ensembl chr15:49,813,447...49,835,051
JBrowse link
G ENSA endosulfine alpha involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:125,973,344...125,980,839
Ensembl chr 1:129,599,495...129,629,779
JBrowse link
G IGBP1 immunoglobulin binding protein 1 involved_in ISO (MGI:4457251|PMID:17438131), (MGI:4457259|PMID:9792806) UniProt PMID:9792806 PMID:17438131 MGI:4457251 MGI:4457259 NCBI chr  X:59,401,426...59,434,363
Ensembl chr  X:69,460,734...69,493,616
JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:10,318,455...10,428,469 JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
G PPP1R16B protein phosphatase 1 regulatory subunit 16B involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:35,130,114...35,248,031
Ensembl chr20:36,237,535...36,354,329
JBrowse link
G PPP1R8 protein phosphatase 1 regulatory subunit 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:27,092,588...27,113,399
Ensembl chr 1:28,133,358...28,152,588
JBrowse link
G PTPA protein phosphatase 2 phosphatase activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:100,236,607...100,274,273
Ensembl chr 9:128,896,584...128,934,651
JBrowse link
G SLC4A1AP solute carrier family 4 member 1 adaptor protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:27,661,396...27,692,923
Ensembl chr2A:27,747,433...27,778,466
JBrowse link
G SNIP1 Smad nuclear interacting protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:36,807,488...36,827,347
Ensembl chr 1:38,155,375...38,176,803
JBrowse link
G YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:41,216,071...41,238,893
Ensembl chr20:42,309,155...42,331,695
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon acts_upstream_of_or_within ISO (PMID:12796778) MGI PMID:12796778 NCBI chr17:1,332,004...1,387,120
Ensembl chr17:1,229,080...1,285,470
JBrowse link
negative regulation of protein tyrosine phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:11500506 RGD:13508599 NCBI chr 3:50,154,731...50,187,948
Ensembl chr 3:51,398,981...51,421,988
JBrowse link
peptidyl-tyrosine dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPN5 protein tyrosine phosphatase non-receptor type 5 ISO RGD PMID:9857190 PMID:19625523 RGD:10044039 RGD:9835004 NCBI chr11:18,758,285...18,822,845
Ensembl chr11:18,673,366...18,711,885
JBrowse link
G PTPRZ1 protein tyrosine phosphatase receptor type Z1 ISO RGD PMID:21890632 RGD:9590130 NCBI chr 7:113,882,557...114,073,283
Ensembl chr 7:126,569,630...126,758,155
JBrowse link
positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
positive regulation of peptidyl-serine dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NCK1 NCK adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:133,902,463...133,990,414
Ensembl chr 3:141,427,870...141,451,444
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
G PPP1R15B protein phosphatase 1 regulatory subunit 15B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:180,002,895...180,014,956
Ensembl chr 1:184,293,640...184,302,316
JBrowse link
positive regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JAK2 Janus kinase 2 ISO Ptpn11 activity RGD PMID:17021051 RGD:1641809 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626
JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:23219599 RGD:9835413 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:24265448 RGD:8693600 NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786
JBrowse link
positive regulation of protein dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor ISO activates type 2a protein phosphatase in ventricular myocytes RGD PMID:12234781 RGD:1625280 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760
JBrowse link
G AMBRA1 autophagy and beclin 1 regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,355,026...46,556,091
Ensembl chr11:46,905,454...47,103,205
JBrowse link
G ANKLE2 ankyrin repeat and LEM domain containing 2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr12:130,091,476...130,123,533
Ensembl chr12:134,805,830...134,835,140
JBrowse link
G CALM1 calmodulin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:71,015,099...71,026,322
Ensembl chr19:52,121,687...52,131,135
JBrowse link
G CALM2 calmodulin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:47,274,722...47,290,861
Ensembl chr2A:48,204,518...48,220,697
JBrowse link
G CALM3 calmodulin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:43,593,069...43,602,550
Ensembl chr19:52,121,687...52,131,135
JBrowse link
G CAMTA1 calmodulin binding transcription activator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:5,549,742...6,532,568
Ensembl chr 1:6,824,687...7,781,265
JBrowse link
G CDCA2 cell division cycle associated 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:22801782) MGI
Ensembl
PMID:22801782 GO_REF:0000107 NCBI chr 8:24,739,705...24,788,898
Ensembl chr 8:21,650,086...21,697,584
JBrowse link
G CDH5 cadherin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,684,545...46,722,740
Ensembl chr16:65,787,370...65,825,360
JBrowse link
G CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr16:30,288,552...30,300,444
Ensembl chr16:49,172,711...49,184,592
JBrowse link
G DLC1 DLC1 Rho GTPase activating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:12,282,190...12,809,770
Ensembl chr 8:9,037,742...9,460,233
JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,579,300...130,589,560
Ensembl chr 1:134,185,385...134,194,851
JBrowse link
G LOC100991256 leukocyte immunoglobulin-like receptor subfamily B member 3 involved_in ISO (MGI:5511064|PMID:24052308) ARUK-UCL PMID:24052308 MGI:5511064 NCBI chr19:51,148,567...51,154,764 JBrowse link
G NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor involved_in ISO PMID:18303947 UniProt PMID:18303947 RGD:8553324 NCBI chr 9:108,518,698...108,531,316
Ensembl chr 9:137,482,420...137,495,990
JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:16675464 RGD:8693430 NCBI chr19:9,389,829...9,404,099
Ensembl chr19:10,053,254...10,066,853
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560
JBrowse link
G PPIA peptidylprolyl isomerase A involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545
JBrowse link
G PPP1R16B protein phosphatase 1 regulatory subunit 16B involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:35,130,114...35,248,031
Ensembl chr20:36,237,535...36,354,329
JBrowse link
G PPP1R7 protein phosphatase 1 regulatory subunit 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:22801782) MGI
Ensembl
PMID:22801782 GO_REF:0000107 NCBI chr2B:128,418,212...128,452,417
Ensembl chr2B:247,214,882...247,248,761
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:15728831 PMID:16884689 RGD:13515114 RGD:8554004 NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786
JBrowse link
G PPP2R5A protein phosphatase 2 regulatory subunit B'alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:187,853,674...187,926,318
Ensembl chr 1:192,716,546...192,788,328
JBrowse link
G PPP2R5D protein phosphatase 2 regulatory subunit B'delta involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18496528) Ensembl
MGI
PMID:18496528 GO_REF:0000107 NCBI chr 6:42,576,759...42,604,609
Ensembl chr 6:43,871,915...43,899,183
JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G PTBP1 polypyrimidine tract binding protein 1 involved_in ISO (PMID:23853098) BHF-UCL PMID:23853098 NCBI chr19:319,953...334,945 JBrowse link
G PTPA protein phosphatase 2 phosphatase activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:100,236,607...100,274,273
Ensembl chr 9:128,896,584...128,934,651
JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in ISO (PMID:19279008) BHF-UCL PMID:19279008 NCBI chr11:6,521,812...6,526,349 JBrowse link
G SPPL3 signal peptide peptidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:118,351,199...118,489,579
Ensembl chr12:121,723,881...121,773,429
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 ISO RGD PMID:12435803 RGD:633811 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935
JBrowse link
G OAZ3 ornithine decarboxylase antizyme 3 ISO RGD PMID:21712390 RGD:7245493 NCBI chr 1:127,121,375...127,129,940
Ensembl chr 1:130,765,290...130,773,859
JBrowse link
regulation of protein dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL3 interleukin 3 acts_upstream_of_or_within ISO (PMID:12944463) MGI PMID:12944463 NCBI chr 5:127,483,843...127,486,388
Ensembl chr 5:133,647,667...133,650,213
JBrowse link
G PPP1R16B protein phosphatase 1 regulatory subunit 16B involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:35,130,114...35,248,031
Ensembl chr20:36,237,535...36,354,329
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16447
    metabolic process 10324
      primary metabolic process 8935
        protein metabolic process 3941
          protein modification process 1939
            protein dephosphorylation 73
              negative regulation of protein dephosphorylation + 19
              peptidyl-N-phospho-arginine dephosphorylation 0
              peptidyl-histidine dephosphorylation 0
              peptidyl-serine dephosphorylation + 7
              peptidyl-threonine dephosphorylation 0
              peptidyl-tyrosine dephosphorylation + 2
              positive regulation of protein dephosphorylation + 34
              regulation of protein dephosphorylation + 52
              regulation of translational initiation by eIF2 alpha dephosphorylation + 1
Path 2
Term Annotations click to browse term
  biological_process 16447
    metabolic process 10324
      cellular metabolic process 8638
        phosphorus metabolic process 1750
          phosphate-containing compound metabolic process 1721
            dephosphorylation 130
              protein dephosphorylation 73
                negative regulation of protein dephosphorylation + 19
                peptidyl-N-phospho-arginine dephosphorylation 0
                peptidyl-histidine dephosphorylation 0
                peptidyl-serine dephosphorylation + 7
                peptidyl-threonine dephosphorylation 0
                peptidyl-tyrosine dephosphorylation + 2
                positive regulation of protein dephosphorylation + 34
                regulation of protein dephosphorylation + 52
                regulation of translational initiation by eIF2 alpha dephosphorylation + 1
paths to the root