YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) - Rat Genome Database

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Gene: YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) Pan paniscus
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Symbol: YWHAB
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
RGD ID: 11994873
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); protein targeting (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; mTOR signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH brain ischemia (ortholog); focal epilepsy (ortholog); T-Cell Immunodeficiency, Recurrent Infections, and Autoimmunity with or without Cardiac Malformations (ortholog); FOUND IN protein-containing complex (ortholog); transcription repressor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 14-3-3 protein beta/alpha; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22150,618,382 - 50,641,330 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12050,611,587 - 50,634,433 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02041,216,071 - 41,238,893 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12042,309,101 - 42,331,705 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2042,309,155 - 42,331,695 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
YWHAB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22150,618,382 - 50,641,330 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12050,611,587 - 50,634,433 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02041,216,071 - 41,238,893 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12042,309,101 - 42,331,705 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2042,309,155 - 42,331,695 (+)Ensemblpanpan1.1panPan2
YWHAB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382044,885,705 - 44,908,532 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2044,885,702 - 44,908,532 (+)EnsemblGRCh38hg38GRCh38
GRCh372043,514,346 - 43,537,173 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362042,947,758 - 42,970,575 (+)NCBINCBI36Build 36hg18NCBI36
Build 342042,947,757 - 42,970,574NCBI
Celera2040,222,982 - 40,245,799 (+)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2040,256,131 - 40,279,005 (+)NCBIHuRef
CHM1_12043,417,179 - 43,440,099 (+)NCBICHM1_1
T2T-CHM13v2.02046,621,568 - 46,644,395 (+)NCBIT2T-CHM13v2.0
Ywhab
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392163,837,082 - 163,860,508 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2163,836,880 - 163,860,508 (+)EnsemblGRCm39 Ensembl
GRCm382163,995,197 - 164,018,588 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2163,994,960 - 164,018,588 (+)EnsemblGRCm38mm10GRCm38
MGSCv372163,820,933 - 163,844,323 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362163,686,638 - 163,710,028 (+)NCBIMGSCv36mm8
Celera2169,925,360 - 169,948,799 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map284.59NCBI
Ywhab
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,078,904 - 173,101,508 (+)NCBIGRCr8
mRatBN7.23152,659,663 - 152,682,105 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3152,659,651 - 152,682,105 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3156,467,118 - 156,489,555 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03164,966,056 - 164,988,493 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03162,710,239 - 162,732,648 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03160,391,108 - 160,399,931 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3160,391,106 - 160,399,931 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03166,577,934 - 166,586,801 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43154,926,025 - 154,948,297 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13154,832,060 - 154,854,385 (+)NCBI
Celera3151,308,216 - 151,330,624 (+)NCBICelera
Cytogenetic Map3q42NCBI
Ywhab
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544512,448,760 - 12,474,251 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544512,451,644 - 12,474,251 (-)NCBIChiLan1.0ChiLan1.0
YWHAB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12432,304,808 - 32,325,789 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2432,304,812 - 32,323,938 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2431,950,457 - 31,971,435 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02433,016,092 - 33,036,942 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2433,016,085 - 33,059,979 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12432,277,256 - 32,298,231 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02432,392,197 - 32,412,966 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02432,933,875 - 32,954,868 (+)NCBIUU_Cfam_GSD_1.0
Ywhab
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640192,378,451 - 192,399,435 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365147,830,387 - 7,853,262 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365147,832,094 - 7,853,170 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YWHAB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1747,298,044 - 47,319,285 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11747,298,020 - 47,317,826 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21752,794,145 - 52,815,419 (+)NCBISscrofa10.2Sscrofa10.2susScr3
YWHAB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,904,588 - 18,927,461 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl218,906,666 - 18,927,374 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605067,571,578 - 67,594,333 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ywhab
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247909,574,027 - 9,593,825 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247909,574,003 - 9,593,821 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000049631   ⟹   ENSPPAP00000026795
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2042,309,155 - 42,331,695 (+)Ensembl
RefSeq Acc Id: XM_008951322   ⟹   XP_008949570
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22150,618,382 - 50,641,330 (+)NCBI
NHGRI_mPanPan12050,611,587 - 50,634,433 (+)NCBI
Mhudiblu_PPA_v02041,216,073 - 41,238,893 (+)NCBI
PanPan1.12042,309,101 - 42,331,705 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008951323   ⟹   XP_008949571
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22150,618,525 - 50,641,330 (+)NCBI
NHGRI_mPanPan12050,611,629 - 50,634,433 (+)NCBI
Mhudiblu_PPA_v02041,216,071 - 41,238,893 (+)NCBI
PanPan1.12042,309,155 - 42,331,705 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055104513   ⟹   XP_054960488
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22150,618,819 - 50,641,330 (+)NCBI
NHGRI_mPanPan12050,611,936 - 50,634,433 (+)NCBI
RefSeq Acc Id: XM_063600788   ⟹   XP_063456858
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22150,618,877 - 50,641,330 (+)NCBI
RefSeq Acc Id: XM_063600789   ⟹   XP_063456859
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22150,618,469 - 50,641,330 (+)NCBI
RefSeq Acc Id: XM_063600790   ⟹   XP_063456860
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22150,618,519 - 50,641,330 (+)NCBI
RefSeq Acc Id: XP_008949570   ⟸   XM_008951322
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BJ33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008949571   ⟸   XM_008951323
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BJ33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000026795   ⟸   ENSPPAT00000049631
RefSeq Acc Id: XP_054960488   ⟸   XM_055104513
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063456859   ⟸   XM_063600789
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063456860   ⟸   XM_063600790
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063456858   ⟸   XM_063600788
- Peptide Label: isoform X1
Protein Domains
14-3-3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036479 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000049631.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.190.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 14-3-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  14-3-3_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  14-3-3_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  14-3-3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report bta:286863 UniProtKB/Swiss-Prot
  pps:100983141 UniProtKB/TrEMBL
NCBI Gene YWHAB ENTREZGENE
PANTHER 14-3-3 PROTEIN BETA/ALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18860 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 14-3-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF 14-3-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS 1433ZETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE 1433_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1433_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 14_3_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48445 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt 1433B_BOVIN UniProtKB/Swiss-Prot
  A0A2R9BJ33 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary P29358 UniProtKB/Swiss-Prot
  Q0VCL1 UniProtKB/Swiss-Prot