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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein dephosphorylation
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Accession:GO:0035308 term browser browse the term
Definition:Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein.
Synonyms:exact_synonym: down regulation of protein amino acid dephosphorylation;   downregulation of protein amino acid dephosphorylation;   negative regulation of protein amino acid dephosphorylation
 narrow_synonym: inhibition of protein amino acid dephosphorylation


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negative regulation of protein dephosphorylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap1 A-kinase anchoring protein 1 IMP NFATc3 RGD PMID:19358331 RGD:2312604 NCBI chr10:76,151,013...76,183,987
Ensembl chr10:76,151,038...76,166,276
JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:81,949,577...81,972,054
Ensembl chr 8:81,949,877...81,968,589
JBrowse link
G Ensa endosulfine alpha IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:197,752,544...197,759,882
Ensembl chr 2:197,752,544...197,759,882
JBrowse link
G Igbp1 immunoglobulin binding protein 1 ISO (MGI:MGI:4457251|PMID:17438131), (MGI:MGI:4457259|PMID:9792806) RGD PMID:9792806, PMID:17438131 MGI:MGI:4457251, MGI:MGI:4457259 NCBI chr  X:70,322,764...70,345,005
Ensembl chr  X:70,322,755...70,345,005
JBrowse link
G LOC100360828 cAMP-regulated phosphoprotein 19-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:119,105,962...119,106,371
Ensembl chr 8:81,949,877...81,968,589
JBrowse link
G Mfhas1 malignant fibrous histiocytoma amplified sequence 1 ISO (PMID:28609714) RGD PMID:28609714 NCBI chr16:60,120,457...60,208,550
Ensembl chr16:60,128,201...60,208,462
JBrowse link
G Ppp1r11 protein phosphatase 1, regulatory (inhibitor) subunit 11 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:2,094,931...2,098,438
Ensembl chr20:2,094,931...2,098,433
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A ISO (PMID:11564868) RGD PMID:11564868 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B ISO (PMID:21466834) RGD PMID:21466834 NCBI chr 3:155,160,474...155,267,002
Ensembl chr 3:155,160,481...155,262,941
JBrowse link
G Ppp1r8 protein phosphatase 1, regulatory subunit 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:151,012,035...151,029,227
Ensembl chr 5:151,011,319...151,029,233
JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator ISO (PMID:16916641) RGD PMID:16916641 NCBI chr 3:8,982,122...9,012,585
Ensembl chr 3:8,982,122...9,012,585
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta ISO (PMID:17255105) RGD PMID:17255105 NCBI chr 3:160,391,108...160,399,931
Ensembl chr 3:160,391,106...160,399,931
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon ISO (MGI:MGI:2665158|PMID:12796778) RGD PMID:12796778 MGI:MGI:2665158 NCBI chr10:63,884,338...63,921,709
Ensembl chr10:63,884,338...63,921,709
JBrowse link
negative regulation of myosin-light-chain-phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta IEA
ISO
GO_REF:0000107
(PMID:25816133)
Ensembl
RGD
PMID:25816133 GO_REF:0000107 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Mprip myosin phosphatase Rho interacting protein IMP RGD PMID:17661354 RGD:9685557 NCBI chr10:46,018,397...46,133,580
Ensembl chr10:46,018,659...46,133,571
JBrowse link
G Nckap1l NCK associated protein 1 like ISO
ISS
(PMID:16417406)
GO_REF:0000024
RGD
UniProt
PMID:16417406 GO_REF:0000024 NCBI chr 7:145,068,239...145,113,507
Ensembl chr 7:145,068,286...145,113,507
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 IEA
ISO
GO_REF:0000107
UniProtKB:O75116 (PMID:25816133)
Ensembl
RGD
PMID:25816133 GO_REF:0000107 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 IEA
ISO
GO_REF:0000107
UniProtKB:Q13464 (PMID:25816133)
Ensembl
RGD
PMID:25816133 GO_REF:0000107 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:25816133) RGD PMID:25816133 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
negative regulation of peptidyl-serine dephosphorylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B ISO (PMID:25007873) RGD PMID:25007873 NCBI chr 3:155,160,474...155,267,002
Ensembl chr 3:155,160,481...155,262,941
JBrowse link
G Swap70 switching B-cell complex subunit SWAP70 ISO (MGI:MGI:5554982|PMID:23921380) RGD PMID:23921380 MGI:MGI:5554982 NCBI chr 1:174,862,683...174,924,101
Ensembl chr 1:174,862,698...174,924,078
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon ISO (PMID:11953308) RGD PMID:11953308 NCBI chr10:63,884,338...63,921,709
Ensembl chr10:63,884,338...63,921,709
JBrowse link
negative regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07027306.1 IEA GO_REF:0000108 GOC GO_REF:0000108 Ensembl chr17:23,661,429...23,761,079 JBrowse link
G AABR07051376.1 IEA GO_REF:0000108 GOC GO_REF:0000108 Ensembl chr 3:7,035,169...7,038,421 JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:81,949,577...81,972,054
Ensembl chr 8:81,949,877...81,968,589
JBrowse link
G Bod1 biorientation of chromosomes in cell division 1 ISO
IBA
(PMID:24157919)
PMID:21873635
RGD PMID:24157919, PMID:21873635 RGD:13792537 NCBI chr10:16,259,728...16,266,069
Ensembl chr10:16,259,728...16,266,061
JBrowse link
G Bod1l1 biorientation of chromosomes in cell division 1-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:73,738,137...73,792,935
Ensembl chr14:73,738,137...73,791,656
JBrowse link
G Cabin1 calcineurin binding protein 1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr20:13,836,032...13,963,003
Ensembl chr20:13,836,030...13,963,003
JBrowse link
G Cmya5 cardiomyopathy associated 5 ISO (MGI:MGI:5056263|PMID:21427212) RGD PMID:21427212 MGI:MGI:5056263 NCBI chr 2:22,646,694...22,744,536
Ensembl chr 2:22,646,712...22,744,407
JBrowse link
G Cry2 cryptochrome circadian regulator 2 ISO (PMID:9383998) RGD PMID:9383998 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110
JBrowse link
G Ensa endosulfine alpha IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:197,752,544...197,759,882
Ensembl chr 2:197,752,544...197,759,882
JBrowse link
G Fam122a family with sequence similarity 122A IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:242,372,458...242,373,764
Ensembl chr 1:242,372,458...242,373,764
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A ISO (PMID:7592869) RGD PMID:7592869 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B ISO (PMID:7592869) RGD PMID:7592869 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Lmtk2 lemur tyrosine kinase 2 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr12:12,409,876...12,546,111
Ensembl chr12:12,409,876...12,546,111
JBrowse link
G LOC100360828 cAMP-regulated phosphoprotein 19-like IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:119,105,962...119,106,371
Ensembl chr 8:81,949,877...81,968,589
JBrowse link
G LOC497940 similar to RIKEN cDNA 2810408A11 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:56,506,834...56,511,716
Ensembl chr10:56,507,553...56,511,583
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like ISO
IEA
(PMID:20538976)
GO_REF:0000107
RGD
Ensembl
PMID:20538976 GO_REF:0000107 NCBI chr17:89,839,562...89,875,855
Ensembl chr17:89,742,140...89,876,825
JBrowse link
G Myoz1 myozenin 1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr15:4,077,066...4,084,306
Ensembl chr15:4,077,091...4,084,314
JBrowse link
G Phactr1 phosphatase and actin regulator 1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:23,245,423...23,761,207 JBrowse link
G Phactr2 phosphatase and actin regulator 2 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:7,352,050...7,633,991
Ensembl chr 1:7,355,154...7,480,825
JBrowse link
G Phactr3 phosphatase and actin regulator 3 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:173,798,542...173,871,386
Ensembl chr 3:173,798,545...173,871,904
JBrowse link
G Phactr4 phosphatase and actin regulator 4 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:150,533,895...150,609,423
Ensembl chr 5:150,546,430...150,609,352
JBrowse link
G Ppia peptidylprolyl isomerase A IDA RGD PMID:19832699 RGD:7247324 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr20:3,329,677...3,344,286
Ensembl chr20:3,329,677...3,344,286
JBrowse link
G Ppp1r11 protein phosphatase 1, regulatory (inhibitor) subunit 11 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:2,094,931...2,098,438
Ensembl chr20:2,094,931...2,098,433
JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:87,224,683...87,232,842
Ensembl chr 1:87,224,677...87,232,848
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:222,229,835...222,231,945
Ensembl chr 1:222,229,835...222,231,944
JBrowse link
G Ppp1r14c protein phosphatase 1, regulatory (inhibitor) subunit 14c IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:39,811,314...39,923,071
Ensembl chr 1:39,811,314...39,923,057
JBrowse link
G Ppp1r14d protein phosphatase 1, regulatory (inhibitor) subunit 14D IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:111,022,920...111,037,166
Ensembl chr 3:111,022,923...111,037,425
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A ISO (PMID:11564868) RGD PMID:11564868 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp1r17 protein phosphatase 1, regulatory subunit 17 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:86,275,130...86,292,435
Ensembl chr 4:86,275,717...86,292,431
JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory (inhibitor) subunit 1A IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:145,146,480...145,154,131
Ensembl chr 7:145,146,481...145,154,131
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B ISO (PMID:10807923) RGD PMID:10807923 NCBI chr10:86,303,727...86,312,770
Ensembl chr10:86,303,727...86,312,762
JBrowse link
G Ppp1r1c protein phosphatase 1, regulatory (inhibitor) subunit 1C IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:66,673,060...66,783,501
Ensembl chr 3:66,673,071...66,780,075
JBrowse link
G Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr11:72,748,789...73,034,683
Ensembl chr11:73,022,063...73,034,682
JBrowse link
G Ppp1r36 protein phosphatase 1, regulatory subunit 36 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:99,443,753...99,464,143
Ensembl chr 6:99,444,013...99,464,143
JBrowse link
G Ppp1r37 protein phosphatase 1, regulatory subunit 37 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:80,439,718...80,471,527
Ensembl chr 1:80,439,718...80,471,527
JBrowse link
G Ppp1r8 protein phosphatase 1, regulatory subunit 8 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:151,012,035...151,029,227
Ensembl chr 5:151,011,319...151,029,233
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B IDA
IMP
RGD PMID:12016225, PMID:10585469 RGD:625568, RGD:9999389 NCBI chr10:82,800,704...82,816,735
Ensembl chr10:82,800,704...82,816,731
JBrowse link
G Ppp4r4 protein phosphatase 4, regulatory subunit 4 ISO
IBA
(PMID:18715871)
PMID:21873635
RGD PMID:18715871, PMID:21873635 RGD:13792537 NCBI chr 6:127,400,585...127,497,280
Ensembl chr 6:127,400,585...127,497,280
JBrowse link
G Ptn pleiotrophin IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator ISO (PMID:16916641) RGD PMID:16916641 NCBI chr 3:8,982,122...9,012,585
Ensembl chr 3:8,982,122...9,012,585
JBrowse link
G RGD1309049 similar to RIKEN cDNA 4933415F23 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:29,336,288...29,337,922
Ensembl chr 9:29,336,290...29,337,922
JBrowse link
G Rgn regucalcin IMP RGD PMID:10922512 RGD:9590172 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr18:36,371,041...36,471,020
Ensembl chr18:36,371,041...36,471,015
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 ISO (PMID:24709986) RGD PMID:24709986 NCBI chr12:23,954,563...23,987,155
Ensembl chr12:23,954,574...23,987,271
JBrowse link
G Tiprl TOR signaling pathway regulator ISO (PMID:17384681) RGD PMID:17384681 NCBI chr13:83,478,966...83,504,448
Ensembl chr13:83,478,974...83,504,494
JBrowse link
negative regulation of protein serine/threonine phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r14d protein phosphatase 1, regulatory (inhibitor) subunit 14D ISS
ISO
GO_REF:0000024
(PMID:12974676)
UniProt
RGD
PMID:12974676 GO_REF:0000024 NCBI chr 3:111,022,920...111,037,166
Ensembl chr 3:111,022,923...111,037,425
JBrowse link
negative regulation of protein tyrosine phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:11500506 RGD:13508599 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Mgat5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase ISO (PMID:24846175) RGD PMID:24846175 NCBI chr13:43,850,744...44,157,860
Ensembl chr13:43,850,751...44,157,924
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      negative regulation of metabolic process 3315
        negative regulation of cellular metabolic process 2779
          negative regulation of cellular protein metabolic process 1136
            negative regulation of protein modification process 637
              negative regulation of protein dephosphorylation 61
                negative regulation of peptidyl-serine dephosphorylation 3
                negative regulation of phosphoprotein phosphatase activity + 54
Path 2
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      organic substance metabolic process 11636
        macromolecule metabolic process 10081
          protein metabolic process 6214
            regulation of protein metabolic process 2958
              regulation of cellular protein metabolic process 2806
                regulation of protein modification process 1960
                  regulation of protein dephosphorylation 137
                    negative regulation of protein dephosphorylation 61
                      negative regulation of peptidyl-serine dephosphorylation 3
                      negative regulation of phosphoprotein phosphatase activity + 54
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.