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ONTOLOGY REPORT - ANNOTATIONS

Term:heart field specification
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Accession:GO:0003128 term browser browse the term
Definition:The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop.


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heart field specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (PMID:26295701) RGD PMID:26295701 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
heart induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO
ISS		 (PMID:19736317)
GO_REF:0000024		 RGD
UniProt		 PMID:19736317 GO_REF:0000024 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in ISO
ISS
IEA		 (PMID:20702560)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:20702560 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Gata5 GATA binding protein 5 involved_in ISO (MGI:5286818|PMID:21633169) RGD PMID:21633169 MGI:5286818 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:3835736|PMID:18297060), (MGI:4441249|PMID:18593560) RGD PMID:18297060 PMID:18593560 MGI:3835736 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
primary heart field specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO		 GO_REF:0000024
(MGI:3830899|PMID:16680724)		 UniProt
RGD		 PMID:16680724 GO_REF:0000024 MGI:3830899 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Wnt11 Wnt family member 11 involved_in ISO UniProtKB:P22725 (MGI:5424267|PMID:22569553) RGD PMID:22569553 MGI:5424267 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA		 UniProtKB:P48615 (MGI:5424267|PMID:22569553)
GO_REF:0000107		 RGD
Ensembl		 PMID:22569553 GO_REF:0000107 MGI:5424267 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
secondary heart field specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:96522 (PMID:22711842)		 Ensembl
RGD		 PMID:22711842 GO_REF:0000107 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:20702560)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:20702560 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Foxh1 forkhead box H1 involved_in ISO (MGI:3055632|PMID:15363409) RGD PMID:15363409 MGI:3055632 NCBI chr 7:108,387,969...108,391,566
Ensembl chr 7:108,387,969...108,390,049 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in ISO
IEA		 (PMID:20520780)
GO_REF:0000107		 RGD
Ensembl		 PMID:20520780 GO_REF:0000107 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5770180|PMID:26822476)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:26822476 GO_REF:0000024 GO_REF:0000107 MGI:5770180 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO		 GO_REF:0000024
(MGI:3578591|PMID:15890826)		 UniProt
RGD		 PMID:15890826 GO_REF:0000024 MGI:3578591 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:1270862|MGI:3583755 (PMID:22711842) RGD PMID:22711842 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Smarcd3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 acts_upstream_of_or_within ISO MGI:2148567 (PMID:17519332) RGD PMID:17519332 NCBI chr 4:10,548,693...10,580,334
Ensembl chr 4:10,548,751...10,580,326 		JBrowse link
G Wnt11 Wnt family member 11 involved_in ISO UniProtKB:P22725 (MGI:5424267|PMID:22569553) RGD PMID:22569553 MGI:5424267 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA		 UniProtKB:P48615 (MGI:5424267|PMID:22569553)
GO_REF:0000107		 RGD
Ensembl		 PMID:22569553 GO_REF:0000107 MGI:5424267 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    multicellular organismal process 8852
      pattern specification process 498
        regionalization 453
          specification of animal organ identity 41
            heart field specification 18
              heart induction + 8
              primary heart field specification 3
              secondary heart field specification 11
Path 2
Term Annotations click to browse term
  biological_process 20115
    developmental process 7008
      anatomical structure development 6530
        multicellular organism development 5268
          system development 4550
            circulatory system development 1373
              heart development 744
                heart morphogenesis 296
                  heart formation 35
                    heart field specification 18
                      heart induction + 8
                      primary heart field specification 3
                      secondary heart field specification 11
paths to the root