Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tectorigenin
go back to main search page
Accession:CHEBI:9429 term browser browse the term
Definition:A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 5, 7 and 4' respectively.
Synonyms:exact_synonym: 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
 related_synonym: 5,7,4'-trihydroxy-6-methoxyisoflavone;   Formula=C16H12O6;   InChI=1S/C16H12O6/c1-21-16-11(18)6-12-13(15(16)20)14(19)10(7-22-12)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3;   InChIKey=OBBCRPUNCUPUOS-UHFFFAOYSA-N;   SMILES=COc1c(O)cc2occ(-c3ccc(O)cc3)c(=O)c2c1O
 xref: CAS:548-77-6;   HMDB:HMDB0042024;   KEGG:C10534;   KNApSAcK:C00002577;   LIPID_MAPS_instance:LMPK12050385
 xref_mesh: MESH:C120039
 xref: PMID:23461431;   PMID:24380276;   PMID:25480515;   PMID:25856699;   Reaxys:305601;   Wikipedia:Tectorigenin


show annotations for term's descendants           Sort by:
tectorigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 multiple interactions EXP [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCB11 mRNA; [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCB11 protein CTD PMID:37348807 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 multiple interactions EXP [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCC2 protein CTD PMID:37348807 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 multiple interactions EXP [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCC4 protein CTD PMID:37348807 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631 		JBrowse link
G Cat catalase multiple interactions EXP [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased activity of CAT protein CTD PMID:37348807 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions EXP tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of CPT1A mRNA] CTD PMID:35390440 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733 		JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 multiple interactions EXP tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of CYP7A1 mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of CYP7A1 protein] CTD PMID:35390440 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633 		JBrowse link
G Fasn fatty acid synthase multiple interactions EXP tectorigenin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in increased expression of FASN protein] CTD PMID:35390440 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of GCLC protein; tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of GCLC mRNA] CTD PMID:37348807 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767 		JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions EXP [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of GCLM protein; tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of GCLM mRNA] CTD PMID:37348807 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions EXP tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of GPT protein] CTD PMID:37348807 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of HMOX1 protein; tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of HMOX1 mRNA] CTD PMID:37348807 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions EXP [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of NFE2L2 protein; tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NFE2L2 mRNA] CTD PMID:37348807 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP tectorigenin inhibits the reaction [Dietary Fats results in increased expression of NFKB1 mRNA] CTD PMID:35390440 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions EXP [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of NQO1 protein CTD PMID:37348807 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions EXP tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 protein]; tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of NR1H4 mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of NR1H4 protein] CTD PMID:35390440 PMID:37348807 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions EXP tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1I3 mRNA] CTD PMID:37348807 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270 		JBrowse link
G Ocln occludin multiple interactions EXP tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of OCLN mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of OCLN protein] CTD PMID:35390440 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of PPARA mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of PPARA protein] CTD PMID:35390440 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP tectorigenin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein] CTD PMID:35390440 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of TJP1 mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of TJP1 protein] CTD PMID:35390440 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP tectorigenin inhibits the reaction [Dietary Fats results in increased expression of TLR4 mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in increased expression of TLR4 protein] CTD PMID:35390440 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP tectorigenin inhibits the reaction [Dietary Fats results in increased expression of TNF mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in increased expression of TNF protein] CTD PMID:35390440 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
tectoridin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-Coenzyme A dehydrogenase, medium chain multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in decreased expression of ACADM mRNA] CTD PMID:20637825 NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269 		JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in decreased expression of ACOX1 mRNA] CTD PMID:20637825 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in decreased expression of CPT1A mRNA] CTD PMID:20637825 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733 		JBrowse link
G Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in decreased expression of CYP4A10 mRNA] CTD PMID:20637825 NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846 		JBrowse link
G Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in decreased expression of CYP4A14 mRNA] CTD PMID:20637825 NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in increased expression of DGAT1 mRNA] CTD PMID:20637825 NCBI chr15:76,386,215...76,396,167
Ensembl chr15:76,386,215...76,396,153 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA] CTD PMID:20637825 NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions EXP [Xiao-Ke-An results in increased abundance of tectoridin] which results in decreased activity of DPP4 protein CTD PMID:32535096 NCBI chr 2:62,160,417...62,242,635
Ensembl chr 2:62,160,417...62,242,575 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in increased expression of GPAM mRNA] CTD PMID:20637825 NCBI chr19:55,056,067...55,115,666
Ensembl chr19:55,055,700...55,115,670 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP tectoridin inhibits the reaction [Ethanol results in decreased expression of PPARA mRNA] CTD PMID:20637825 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22307
    role 22292
      application 21907
        anti-inflammatory agent 17454
          tectorigenin 30
            7-O-methyltectorigenin 0
            tectoridin 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 22307
    subatomic particle 22302
      composite particle 22302
        hadron 22302
          baryon 22302
            nucleon 22302
              atomic nucleus 22302
                atom 22302
                  main group element atom 22182
                    p-block element atom 22182
                      carbon group element atom 21984
                        carbon atom 21924
                          organic molecular entity 21924
                            organic molecule 21750
                              organic cyclic compound 21366
                                organic heterocyclic compound 20382
                                  oxacycle 18915
                                    benzopyran 12238
                                      1-benzopyran 11997
                                        isoflavonoid 4015
                                          isoflavones 3996
                                            hydroxyisoflavone 3931
                                              7-hydroxyisoflavones 3909
                                                tectorigenin 30
                                                  7-O-methyltectorigenin 0
                                                  tectoridin 10
paths to the root