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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:oxalate
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Accession:CHEBI:132952 term browser browse the term
Definition:A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of oxalic acid.
Synonyms:related_synonym: ethanedioic acid anion;   ethanedioic acid anions;   oxalate anion;   oxalate anions;   oxalates;   oxalic acid anion;   oxalic acid anions
 cyclic_relationship: is_conjugate_base_of CHEBI:16995


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calcium oxalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 ISO SIRT1 protein inhibits the reaction [Calcium Oxalate results in increased expression of BAX protein] CTD PMID:34333021 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 ISO SIRT1 protein inhibits the reaction [Calcium Oxalate results in decreased expression of BCL2 protein] CTD PMID:34333021 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage		 ISO SIRT1 protein inhibits the reaction [Calcium Oxalate results in increased cleavage of CASP3 protein] CTD PMID:34333021 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions
decreases expression		 EXP 2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in decreased expression of CAT protein] CTD PMID:37454925 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions		 EXP Calcium Oxalate results in decreased expression of CCL2 protein
2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in decreased expression of CCL2 protein]; [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CCL2 mRNA; [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CCL2 protein; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CCL2 mRNA]; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CCL2 protein]		 CTD PMID:37414240 PMID:37454925 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cd44 CD44 molecule multiple interactions
decreases expression		 EXP 2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in decreased expression of CD44 protein]; [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CD44 mRNA; [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CD44 protein; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CD44 mRNA]; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CD44 protein] CTD PMID:37414240 PMID:37454925 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions
increases expression		 EXP 2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in increased expression of NOX2 protein] CTD PMID:37454925 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 multiple interactions EXP [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CYP2C9 mRNA; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CYP2C9 mRNA] CTD PMID:37414240 NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709 		JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions EXP [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC1 mRNA; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC1 mRNA] CTD PMID:37414240 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac2 histone deacetylase 2 multiple interactions EXP [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC2 mRNA; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC2 mRNA] CTD PMID:37414240 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hdac3 histone deacetylase 3 multiple interactions EXP [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC3 mRNA; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC3 mRNA] CTD PMID:37414240 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hdac8 histone deacetylase 8 multiple interactions EXP [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC8 mRNA; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of HDAC8 mRNA] CTD PMID:37414240 NCBI chr  X:67,385,288...67,593,014
Ensembl chr  X:67,385,289...67,592,923 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO phenyl-N-tert-butylnitrone inhibits the reaction [Calcium Oxalate results in increased expression of HMOX1 protein] CTD PMID:34333021 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression
multiple interactions		 EXP Calcium Oxalate results in increased expression of ITPR1 protein
Losartan inhibits the reaction [Calcium Oxalate results in increased expression of ITPR1 protein]		 CTD PMID:37454925 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 multiple interactions
increases expression		 EXP Losartan inhibits the reaction [Calcium Oxalate results in increased expression of ITPR2 protein] CTD PMID:37454925 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164 		JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 increases expression EXP Calcium Oxalate results in increased expression of ITPR3 protein CTD PMID:37454925 NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337 		JBrowse link
G Nox4 NADPH oxidase 4 increases expression
multiple interactions		 EXP Calcium Oxalate results in increased expression of NOX4 protein
2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in increased expression of NOX4 protein]		 CTD PMID:37454925 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions
decreases expression		 ISO phenyl-N-tert-butylnitrone inhibits the reaction [Calcium Oxalate results in decreased expression of SIRT1 protein]; SIRT1 protein inhibits the reaction [Calcium Oxalate results in decreased expression of BCL2 protein]; SIRT1 protein inhibits the reaction [Calcium Oxalate results in increased cleavage of CASP3 protein]; SIRT1 protein inhibits the reaction [Calcium Oxalate results in increased expression of BAX protein] CTD PMID:34333021 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases expression		 EXP 2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in decreased expression of SOD1 protein] CTD PMID:37454925 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
decreases expression		 EXP 2-aminoethyl diphenylborinate inhibits the reaction [Calcium Oxalate results in decreased expression of SPP1 protein]; [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of SPP1 mRNA; [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of SPP1 protein; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of SPP1 mRNA]; Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of SPP1 protein] CTD PMID:37414240 PMID:37454925 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19893
    chemical entity 19891
      molecular entity 19891
        ion 17093
          anion 16650
            organic anion 6855
              carboxylic acid anion 2500
                dicarboxylic acid anion 253
                  oxalate 20
                    oxalate salt + 0
                    oxalate(1-) + 0
                    oxalate(2-) + 20
Path 2
Term Annotations click to browse term
  CHEBI ontology 19893
    subatomic particle 19891
      composite particle 19891
        hadron 19891
          baryon 19891
            nucleon 19891
              atomic nucleus 19891
                atom 19891
                  main group element atom 19830
                    p-block element atom 19830
                      carbon group element atom 19771
                        carbon atom 19767
                          organic molecular entity 19767
                            organic ion 11452
                              organic anion 6855
                                carboxylic acid anion 2500
                                  dicarboxylic acid anion 253
                                    oxalate 20
                                      oxalate salt + 0
                                      oxalate(1-) + 0
                                      oxalate(2-) + 20
paths to the root