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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:oxalate(2-)
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Accession:CHEBI:30623 term browser browse the term
Definition:A dicarboxylic acid dianion obtained by deprotonation of both carboxy groups of oxalic acid.
Synonyms:exact_synonym: ethanedioate
 related_synonym: Formula=C2O4;   InChI=1S/C2H2O4/c3-1(4)2(5)6/h(H,3,4)(H,5,6)/p-2;   InChIKey=MUBZPKHOEPUJKR-UHFFFAOYSA-L;   OXALATE ION;   SMILES=[O-]C(=O)C([O-])=O;   ethanedioic acid, ion(2-);   ox;   oxalate
 alt_id: CHEBI:14702;   CHEBI:25729;   CHEBI:44820
 xref: Beilstein:1905970;   CAS:338-70-5;   Gmelin:2207;   KEGG:C00209;   PDBeChem:OXL;   Reaxys:1905970;   UM-BBD_compID:c0017
 cyclic_relationship: is_conjugate_base_of CHEBI:46904


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calcium oxalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 ISO SIRT1 protein inhibits the reaction [Calcium Oxalate results in increased expression of BAX protein] CTD PMID:34333021 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 ISO SIRT1 protein inhibits the reaction [Calcium Oxalate results in decreased expression of BCL2 protein] CTD PMID:34333021 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage		 ISO SIRT1 protein inhibits the reaction [Calcium Oxalate results in increased cleavage of CASP3 protein] CTD PMID:34333021 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO phenyl-N-tert-butylnitrone inhibits the reaction [Calcium Oxalate results in increased expression of HMOX1 protein] CTD PMID:34333021 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions
decreases expression		 ISO phenyl-N-tert-butylnitrone inhibits the reaction [Calcium Oxalate results in decreased expression of SIRT1 protein]; SIRT1 protein inhibits the reaction [Calcium Oxalate results in decreased expression of BCL2 protein]; SIRT1 protein inhibits the reaction [Calcium Oxalate results in increased cleavage of CASP3 protein]; SIRT1 protein inhibits the reaction [Calcium Oxalate results in increased expression of BAX protein] CTD PMID:34333021 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19751
    role 19724
      biological role 19722
        biochemical role 19443
          metabolite 19430
            eukaryotic metabolite 19227
              plant metabolite 17860
                oxalate(2-) 5
                  ammonium oxalate 0
                  calcium oxalate 5
                  sodium oxalate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19751
    subatomic particle 19749
      composite particle 19749
        hadron 19749
          baryon 19749
            nucleon 19749
              atomic nucleus 19749
                atom 19749
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19644
                        carbon atom 19640
                          organic molecular entity 19640
                            organic ion 9258
                              organic anion 3110
                                carboxylic acid anion 2446
                                  dicarboxylic acid anion 225
                                    oxalate 5
                                      oxalate(2-) 5
                                        ammonium oxalate 0
                                        calcium oxalate 5
                                        sodium oxalate 0
paths to the root