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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
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Accession:CHEBI:42839 term browser browse the term
Definition:Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring.
Synonyms:exact_synonym: 3'-amino-3'-deoxy-N,N-dimethyladenosine
 related_synonym: 3'-Amino-3'-deoxy-N6,N6-dimethyladenosine;   6-Dimethylamino-9-(3'-ribosylamine)purine;   Formula=C12H18N6O3;   InChI=1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3/t6-,7-,9-,12-/m1/s1;   InChIKey=RYSMHWILUNYBFW-GRIPGOBMSA-N;   Puromycin aminonucleoside;   SMILES=CN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](N)[C@H]1O;   Stylomycin aminonucleoside
 xref: Beilstein:93902;   CAS:58-60-6
 xref_mesh: MESH:D011692
 xref: PMID:323854


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3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme affects activity ISO Puromycin Aminonucleoside affects the activity of ACE protein CTD PMID:1318808 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACMSD aminocarboxymuconate semialdehyde decarboxylase decreases activity ISO Puromycin Aminonucleoside results in decreased activity of ACMSD protein CTD PMID:16711654 NCBI chr 2:134,838,616...134,902,034
Ensembl chr 2:134,838,616...134,902,034 		JBrowse link
G ACTB actin beta decreases expression ISO Puromycin Aminonucleoside results in decreased expression of ACTB protein CTD PMID:19264907 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902 		JBrowse link
G ACTG1 actin gamma 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of ACTG1 protein CTD PMID:19264907 NCBI chr17:81,509,971...81,512,799
Ensembl chr17:81,509,413...81,523,847 		JBrowse link
G ACTR2 actin related protein 2 increases expression ISO Puromycin Aminonucleoside results in increased expression of ACTR2 mRNA; Puromycin Aminonucleoside results in increased expression of ACTR2 protein CTD PMID:19617259 NCBI chr 2:65,227,831...65,271,253
Ensembl chr 2:65,227,788...65,271,253 		JBrowse link
G ACTR3 actin related protein 3 increases expression ISO Puromycin Aminonucleoside results in increased expression of ACTR3 protein CTD PMID:19264907 NCBI chr 2:113,889,934...113,962,596
Ensembl chr 2:113,890,063...113,962,596 		JBrowse link
G AGT angiotensinogen affects expression
decreases expression
increases expression
multiple interactions		 ISO Puromycin Aminonucleoside affects the expression of AGT protein
Puromycin Aminonucleoside results in decreased expression of AGT protein
Puromycin Aminonucleoside results in increased expression of AGT mRNA
[Puromycin Aminonucleoside co-treated with Cholesterol] results in increased expression of AGT mRNA		 CTD PMID:2236972 PMID:8446257 PMID:12495295 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR2 angiotensin II receptor type 2 multiple interactions
increases expression		 ISO [Puromycin Aminonucleoside co-treated with Cholesterol] results in increased expression of AGTR2 mRNA
Puromycin Aminonucleoside results in increased expression of AGTR2 mRNA		 CTD PMID:12495295 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G AGXT2 alanine--glyoxylate aminotransferase 2 increases expression ISO Puromycin Aminonucleoside results in increased expression of AGXT2 protein CTD PMID:19264907 NCBI chr 5:34,998,102...35,047,949
Ensembl chr 5:34,998,101...35,048,135 		JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 multiple interactions
affects localization		 ISO Dexamethasone inhibits the reaction [Puromycin Aminonucleoside affects the localization of AIFM1 protein] CTD PMID:15987750 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879 		JBrowse link
G ALB albumin affects transport
increases secretion
increases expression
affects localization
decreases expression		 ISO Puromycin Aminonucleoside affects the transport of ALB protein
Puromycin Aminonucleoside results in increased secretion of ALB protein
Puromycin Aminonucleoside results in increased expression of ALB mRNA; Puromycin Aminonucleoside results in increased expression of ALB protein
Puromycin Aminonucleoside affects the localization of ALB protein
Puromycin Aminonucleoside results in decreased expression of ALB protein		 CTD PMID:1453496 PMID:3301049 PMID:8413769 PMID:15798086 PMID:19264907 More... NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 increases expression ISO Puromycin Aminonucleoside results in increased expression of ALDH1A2 mRNA CTD PMID:12660332 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866 		JBrowse link
G ANGPT1 angiopoietin 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of ANGPT1 mRNA CTD PMID:17667850 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions
increases expression		 ISO 1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of APEX1 protein] CTD PMID:17035936 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772 		JBrowse link
G APOA1 apolipoprotein A1 decreases response to substance
increases expression		 EXP
ISO		 APOA1 protein results in decreased susceptibility to Puromycin Aminonucleoside
Puromycin Aminonucleoside results in increased expression of APOA1 mRNA; Puromycin Aminonucleoside results in increased expression of APOA1 protein		 CTD PMID:7066357 PMID:7442475 PMID:7595070 PMID:8412754 PMID:8413767 More... NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOA2 apolipoprotein A2 increases expression ISO Puromycin Aminonucleoside results in increased expression of APOA2 protein CTD PMID:7442475 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631 		JBrowse link
G APOA4 apolipoprotein A4 decreases expression
increases expression		 ISO Puromycin Aminonucleoside results in decreased expression of APOA4 protein
Puromycin Aminonucleoside results in increased expression of APOA4 mRNA; Puromycin Aminonucleoside results in increased expression of APOA4 protein		 CTD PMID:7442475 PMID:8412754 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304 		JBrowse link
G APOB apolipoprotein B increases expression ISO Puromycin Aminonucleoside results in increased expression of APOB protein CTD PMID:2725289 PMID:7442475 PMID:8506949 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOE apolipoprotein E decreases response to substance
increases expression
affects expression		 ISO APOE protein results in decreased susceptibility to Puromycin Aminonucleoside
Puromycin Aminonucleoside results in increased expression of APOE protein
Puromycin Aminonucleoside affects the expression of APOE mRNA		 CTD PMID:7442475 PMID:8413767 PMID:12472773 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G AQP2 aquaporin 2 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of AQP2 protein CTD PMID:9013444 NCBI chr12:49,950,737...49,958,878
Ensembl chr12:49,950,737...49,958,878 		JBrowse link
G AQP3 aquaporin 3 (Gill blood group) decreases expression ISO Puromycin Aminonucleoside results in decreased expression of AQP3 protein CTD PMID:9013444 NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596 		JBrowse link
G ARC activity regulated cytoskeleton associated protein increases expression ISO Puromycin Aminonucleoside results in increased expression of ARC mRNA CTD PMID:19617259 NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression
increases expression		 ISO Puromycin Aminonucleoside results in decreased expression of ATP1A1 protein
Puromycin Aminonucleoside results in increased expression of ATP1A1 mRNA		 CTD PMID:11675400 PMID:15075188 NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of ATP1B1 mRNA CTD PMID:11675400 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of ATP2A2 mRNA; Puromycin Aminonucleoside results in decreased expression of ATP2A2 protein CTD PMID:17457379 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093 		JBrowse link
G AVP arginine vasopressin increases expression ISO Puromycin Aminonucleoside results in increased expression of AVP protein CTD PMID:7810534 NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in increased expression of BAX protein
Dinoprostone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BAX protein]
Dexamethasone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BAX protein]		 CTD PMID:15113391 PMID:15987750 PMID:16152783 PMID:16396944 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCAT2 branched chain amino acid transaminase 2 decreases activity
decreases expression		 ISO Puromycin Aminonucleoside results in decreased activity of BCAT2 protein
Puromycin Aminonucleoside results in decreased expression of BCAT2 mRNA		 CTD PMID:9399633 NCBI chr19:48,795,064...48,811,029
Ensembl chr19:48,795,062...48,811,029 		JBrowse link
G BCHE butyrylcholinesterase increases activity ISO Puromycin Aminonucleoside results in increased activity of BCHE protein CTD PMID:1462003 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
increases expression		 ISO [Puromycin Aminonucleoside co-treated with Melatonin] results in increased expression of BCL2 protein
Puromycin Aminonucleoside results in increased expression of BCL2 protein		 CTD PMID:14993511 PMID:15113391 PMID:16152783 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions
decreases expression		 ISO [Puromycin Aminonucleoside co-treated with pifithrin] results in increased expression of BCL2L1 protein; Dexamethasone inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of BCL2L1 protein]
Dinoprostone affects the reaction [Puromycin Aminonucleoside results in decreased expression of BCL2L1 protein]		 CTD PMID:15987750 PMID:16396944 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein increases expression ISO Puromycin Aminonucleoside results in increased expression of BGLAP protein CTD PMID:9154658 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 increases expression ISO Puromycin Aminonucleoside results in increased expression of BIRC5 mRNA; Puromycin Aminonucleoside results in increased expression of BIRC5 protein CTD PMID:19617259 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BMP7 bone morphogenetic protein 7 multiple interactions
decreases expression		 ISO 1,25-dihydroxyvitamin D inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of BMP7 mRNA]; 1,25-dihydroxyvitamin D inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of BMP7 protein]
Puromycin Aminonucleoside results in decreased expression of BMP7 mRNA; Puromycin Aminonucleoside results in decreased expression of BMP7 protein		 CTD PMID:19594554 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 multiple interactions
increases expression		 ISO Drugs, Chinese Herbal inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BMPR2 mRNA]; Fosinopril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BMPR2 mRNA] CTD PMID:17803470 NCBI chr 2:202,376,327...202,567,749
Ensembl chr 2:202,376,327...202,567,751 		JBrowse link
G C3 complement C3 multiple interactions
increases expression
decreases expression		 ISO cobra venom factor inhibits the reaction [Puromycin Aminonucleoside results in increased expression of C3 protein]; mizoribine inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of C3 protein] CTD PMID:8919236 PMID:9250166 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C5 complement C5 multiple interactions EXP
ISO		 CR1 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]]
cobra venom factor inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]]; Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]		 CTD PMID:9250166 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195 		JBrowse link
G C9 complement C9 multiple interactions EXP
ISO		 CR1 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]]
cobra venom factor inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]]; Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]		 CTD PMID:9250166 NCBI chr 5:39,284,140...39,364,495
Ensembl chr 5:39,284,140...39,371,324 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity		 ISO Colforsin inhibits the reaction [Puromycin Aminonucleoside results in increased activity of CASP3 protein]; Dinoprostone inhibits the reaction [Puromycin Aminonucleoside results in increased activity of CASP3 protein]; L-161982 promotes the reaction [Puromycin Aminonucleoside results in increased activity of CASP3 protein] CTD PMID:16396944 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase increases activity
decreases activity
decreases expression
affects activity
multiple interactions		 ISO Puromycin Aminonucleoside results in increased activity of CAT protein
Puromycin Aminonucleoside results in decreased activity of CAT protein
Puromycin Aminonucleoside results in decreased expression of CAT mRNA
Puromycin Aminonucleoside affects the activity of CAT protein
[Methylprednisolone co-treated with Puromycin Aminonucleoside] results in increased activity of CAT protein; Cyclosporine inhibits the reaction [Puromycin Aminonucleoside results in decreased activity of CAT protein]; Puromycin Aminonucleoside results in decreased expression of and results in decreased activity of CAT protein; sho-saiko-to-kyo-shokyo-ka-oren-bukuryo inhibits the reaction [Puromycin Aminonucleoside results in decreased activity of CAT protein]		 CTD PMID:1744988 PMID:1942778 PMID:6246912 PMID:8289993 PMID:9355075 More... NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL1 C-C motif chemokine ligand 1 affects expression ISO Puromycin Aminonucleoside affects the expression of CCL1 mRNA CTD PMID:10867541 NCBI chr17:34,360,328...34,363,233
Ensembl chr17:34,360,328...34,363,233 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 affects expression
increases expression
multiple interactions		 ISO Puromycin Aminonucleoside affects the expression of CCL2 mRNA
Puromycin Aminonucleoside results in increased expression of CCL2 mRNA; Puromycin Aminonucleoside results in increased expression of CCL2 protein
fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of CCL2 mRNA]; Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of CCL2 protein]		 CTD PMID:10867541 PMID:12813006 PMID:16452496 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 affects expression ISO Puromycin Aminonucleoside affects the expression of CCL3 mRNA CTD PMID:10867541 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 affects expression ISO Puromycin Aminonucleoside affects the expression of CCL7 mRNA CTD PMID:10867541 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CD2AP CD2 associated protein multiple interactions
decreases expression		 ISO celecoxib inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CD2AP mRNA] CTD PMID:19194550 NCBI chr 6:47,477,789...47,627,263
Ensembl chr 6:47,477,789...47,627,263 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) multiple interactions
increases expression		 ISO Puromycin Aminonucleoside results in increased expression of and results in increased glycosylation of CD36 protein
Puromycin Aminonucleoside results in increased expression of CD36 mRNA		 CTD PMID:19264907 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CD44 CD44 molecule (IN blood group) increases expression ISO Puromycin Aminonucleoside results in increased expression of CD44 protein CTD PMID:8635280 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO 1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of CDKN1A protein] CTD PMID:17035936 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CHST11 carbohydrate sulfotransferase 11 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of CHST11 mRNA CTD PMID:15585670 NCBI chr12:104,456,948...104,762,014
Ensembl chr12:104,455,295...104,762,014 		JBrowse link
G CHSY1 chondroitin sulfate synthase 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of CHSY1 mRNA CTD PMID:15585670 NCBI chr15:101,175,727...101,252,048
Ensembl chr15:101,175,727...101,252,048 		JBrowse link
G CLDN6 claudin 6 affects localization ISO Puromycin Aminonucleoside affects the localization of CLDN6 protein CTD PMID:18367650 NCBI chr16:3,014,712...3,018,183
Ensembl chr16:3,014,712...3,020,071 		JBrowse link
G CLIC5 chloride intracellular channel 5 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CLIC5 protein CTD PMID:19264907 NCBI chr 6:45,880,827...46,129,819
Ensembl chr 6:45,880,827...46,080,348 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions
increases expression		 ISO 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL1A1 mRNA] CTD PMID:9527400 PMID:16570917 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL3A1 collagen type III alpha 1 chain increases expression ISO Puromycin Aminonucleoside results in increased expression of COL3A1 mRNA CTD PMID:9527400 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G COL4A1 collagen type IV alpha 1 chain multiple interactions
increases expression		 ISO Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA]; FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA] CTD PMID:1762292 PMID:9175058 NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,157 		JBrowse link
G CORIN corin, serine peptidase decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CORIN mRNA; Puromycin Aminonucleoside results in decreased expression of CORIN protein CTD PMID:20613715 NCBI chr 4:47,594,001...47,838,067
Ensembl chr 4:47,593,999...47,838,106 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) multiple interactions EXP CR1 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]] CTD PMID:9250166 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765 		JBrowse link
G CTNNB1 catenin beta 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CTNNB1 protein CTD PMID:12065681 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CTSB cathepsin B decreases activity ISO Puromycin Aminonucleoside results in decreased activity of CTSB protein CTD PMID:10394110 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CTSD cathepsin D increases activity ISO Puromycin Aminonucleoside results in increased activity of CTSD protein CTD PMID:6497855 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CTSH cathepsin H decreases activity ISO Puromycin Aminonucleoside results in decreased activity of CTSH protein CTD PMID:10394110 NCBI chr15:78,921,058...78,945,046
Ensembl chr15:78,921,058...78,949,574 		JBrowse link
G CTSL cathepsin L decreases response to substance
multiple interactions
decreases activity
affects expression		 ISO CTSL gene mutant form results in decreased susceptibility to Puromycin Aminonucleoside
Puromycin Aminonucleoside results in increased activity of and results in increased expression of CTSL protein
Puromycin Aminonucleoside results in decreased activity of CTSL protein
Puromycin Aminonucleoside affects the expression of CTSL mRNA; Puromycin Aminonucleoside affects the expression of CTSL protein		 CTD PMID:10394110 PMID:15197181 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions
decreases expression		 ISO [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; CGB3 protein inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; FSHB protein inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA] CTD PMID:16574160 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of CYP24A1 mRNA CTD PMID:19297354 NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CYP27B1 mRNA CTD PMID:19297354 NCBI chr12:57,762,334...57,767,078
Ensembl chr12:57,762,334...57,768,986 		JBrowse link
G DDC dopa decarboxylase decreases activity ISO Puromycin Aminonucleoside results in decreased activity of DDC protein CTD PMID:16204272 NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405 		JBrowse link
G DDN dendrin decreases expression ISO Puromycin Aminonucleoside results in decreased expression of DDN protein CTD PMID:20588063 NCBI chr12:48,995,149...48,999,375
Ensembl chr12:48,995,149...48,999,375 		JBrowse link
G DES desmin increases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in increased expression of DES protein
triptolide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of DES protein]		 CTD PMID:2183627 PMID:18509322 NCBI chr 2:219,418,377...219,426,734
Ensembl chr 2:219,418,377...219,426,735 		JBrowse link
G DNM3 dynamin 3 increases expression ISO Puromycin Aminonucleoside results in increased expression of DNM3 mRNA CTD PMID:19617259 NCBI chr 1:171,841,498...172,418,466
Ensembl chr 1:171,817,887...172,418,466 		JBrowse link
G ECE1 endothelin converting enzyme 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of ECE1 mRNA; Puromycin Aminonucleoside results in increased expression of ECE1 protein CTD PMID:12972712 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572 		JBrowse link
G ECHS1 enoyl-CoA hydratase, short chain 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of ECHS1 protein CTD PMID:19264907 NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354 		JBrowse link
G EDN1 endothelin 1 multiple interactions
increases expression		 ISO Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA]; FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA]; Puromycin Aminonucleoside inhibits the reaction [EDN1 protein results in increased abundance of Cyclic GMP] CTD PMID:7756592 PMID:9175058 PMID:12972712 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDN3 endothelin 3 multiple interactions ISO Puromycin Aminonucleoside promotes the reaction [EDN3 protein results in increased abundance of Cyclic GMP] CTD PMID:12972712 NCBI chr20:59,300,611...59,325,992
Ensembl chr20:59,300,443...59,325,992 		JBrowse link
G EDNRA endothelin receptor type A increases expression ISO Puromycin Aminonucleoside results in increased expression of EDNRA mRNA CTD PMID:12972712 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G EDNRB endothelin receptor type B multiple interactions
increases expression		 ISO Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDNRB mRNA] CTD PMID:7756592 NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G ETFA electron transfer flavoprotein subunit alpha decreases expression ISO Puromycin Aminonucleoside results in decreased expression of ETFA protein CTD PMID:19264907 NCBI chr15:76,215,353...76,311,469
Ensembl chr15:76,188,555...76,311,730 		JBrowse link
G ETFB electron transfer flavoprotein subunit beta decreases expression ISO Puromycin Aminonucleoside results in decreased expression of ETFB protein CTD PMID:19264907 NCBI chr19:51,345,155...51,366,388
Ensembl chr19:51,345,169...51,366,388 		JBrowse link
G EZR ezrin decreases expression ISO Puromycin Aminonucleoside results in decreased expression of EZR protein CTD PMID:19264907 NCBI chr 6:158,765,748...158,819,368
Ensembl chr 6:158,765,741...158,819,368 		JBrowse link
G FAS Fas cell surface death receptor multiple interactions
increases expression		 ISO Melatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of FAS protein] CTD PMID:14993511 PMID:16152783 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand increases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in increased expression of FASL protein
Melatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of FASLG protein]		 CTD PMID:14993511 PMID:16152783 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FAT1 FAT atypical cadherin 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of FAT1 mRNA; Puromycin Aminonucleoside results in increased expression of FAT1 protein CTD PMID:16014031 NCBI chr 4:186,587,794...186,726,696
Ensembl chr 4:186,587,794...186,726,722 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 increases expression
affects expression		 ISO Puromycin Aminonucleoside results in increased expression of FLT1 protein
Puromycin Aminonucleoside affects the expression of FLT1 mRNA		 CTD PMID:11744811 PMID:14752241 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G FN1 fibronectin 1 increases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in increased expression of FN1 mRNA; Puromycin Aminonucleoside results in increased expression of FN1 protein
Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of FN1 protein]		 CTD PMID:9527400 PMID:12813006 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions
decreases expression		 ISO [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Estradiol]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Progesterone]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Testosterone]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of STAR mRNA]; FSHB protein inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; Puromycin Aminonucleoside inhibits the reaction [GNRH1 protein results in increased secretion of FSHB protein]
Puromycin Aminonucleoside results in decreased expression of FSHB protein		 CTD PMID:12269381 PMID:16574160 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G GNAQ G protein subunit alpha q increases response to substance ISO GNAQ protein results in increased susceptibility to Puromycin Aminonucleoside CTD PMID:16267159 NCBI chr 9:77,716,097...78,031,811
Ensembl chr 9:77,716,097...78,031,811 		JBrowse link
G GNRH1 gonadotropin releasing hormone 1 multiple interactions ISO Puromycin Aminonucleoside inhibits the reaction [GNRH1 protein results in increased secretion of FSHB protein]; Puromycin Aminonucleoside inhibits the reaction [GNRH1 protein results in increased secretion of LHB protein] CTD PMID:12269381 NCBI chr 8:25,419,258...25,425,040
Ensembl chr 8:25,419,258...25,424,654 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions
increases expression		 ISO [Methylprednisolone co-treated with Puromycin Aminonucleoside] results in increased activity of GPX1 protein
Puromycin Aminonucleoside results in increased expression of GPX1 mRNA		 CTD PMID:1942778 PMID:20685819 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX3 glutathione peroxidase 3 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of GPX3 mRNA CTD PMID:20685819 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation		 ISO mizoribine inhibits the reaction [Puromycin Aminonucleoside results in increased phosphorylation of GSK3B protein] CTD PMID:20502051 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of GSTP1 protein CTD PMID:19264907 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GUCA2B guanylate cyclase activator 2B increases expression
affects expression		 ISO Puromycin Aminonucleoside results in increased expression of GUCA2B protein
Puromycin Aminonucleoside affects the expression of GUCA2B mRNA		 CTD PMID:15590761 NCBI chr 1:42,153,410...42,155,820
Ensembl chr 1:42,153,410...42,155,820 		JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase decreases expression ISO Puromycin Aminonucleoside results in decreased expression of HADH protein CTD PMID:19264907 NCBI chr 4:107,989,889...108,035,171
Ensembl chr 4:107,989,714...108,035,241 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase increases activity ISO Puromycin Aminonucleoside results in increased activity of HMGCR protein CTD PMID:3794548 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression		 ISO [piperine co-treated with Cimetidine co-treated with Pyruvates] inhibits the reaction [Puromycin Aminonucleoside results in increased expression of HMOX1 protein]
Puromycin Aminonucleoside results in increased expression of HMOX1 mRNA; Puromycin Aminonucleoside results in increased expression of HMOX1 protein		 CTD PMID:12806184 PMID:20685819 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HPSE heparanase increases expression ISO Puromycin Aminonucleoside results in increased expression of HPSE mRNA; Puromycin Aminonucleoside results in increased expression of HPSE protein CTD PMID:11576343 NCBI chr 4:83,292,461...83,335,153
Ensembl chr 4:83,292,461...83,335,153 		JBrowse link
G HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of HS3ST1 mRNA CTD PMID:15585670 NCBI chr 4:11,393,150...11,434,327
Ensembl chr 4:11,393,150...11,429,564 		JBrowse link
G HS6ST1 heparan sulfate 6-O-sulfotransferase 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of HS6ST1 mRNA CTD PMID:15585670 NCBI chr 2:128,265,480...128,318,868
Ensembl chr 2:128,236,716...128,318,868 		JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO Puromycin Aminonucleoside results in decreased activity of HSD11B2 protein CTD PMID:11981059 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of HSPA5 protein CTD PMID:19264907 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 affects localization ISO Puromycin Aminonucleoside affects the localization of HSPA8 protein CTD PMID:1614035 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of HSPD1 protein CTD PMID:19264907 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of ICAM1 protein CTD PMID:8635280 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL1B interleukin 1 beta increases expression ISO Puromycin Aminonucleoside results in increased expression of IL1B mRNA CTD PMID:17457379 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G ILK integrin linked kinase multiple interactions
increases activity		 ISO mizoribine inhibits the reaction [Puromycin Aminonucleoside results in increased activity of ILK protein] CTD PMID:20502051 NCBI chr11:6,603,774...6,610,870
Ensembl chr11:6,603,708...6,610,874 		JBrowse link
G ITGA3 integrin subunit alpha 3 decreases expression
affects expression		 EXP
ISO		 Puromycin Aminonucleoside results in decreased expression of ITGA3 mRNA; Puromycin Aminonucleoside results in decreased expression of ITGA3 protein
Puromycin Aminonucleoside affects the expression of ITGA3 protein		 CTD PMID:9249603 PMID:10845833 PMID:11274237 PMID:15197181 NCBI chr17:50,056,110...50,090,481
Ensembl chr17:50,055,968...50,090,481 		JBrowse link
G ITGB1 integrin subunit beta 1 decreases expression
increases expression		 EXP
ISO		 Puromycin Aminonucleoside results in decreased expression of ITGB1 mRNA; Puromycin Aminonucleoside results in decreased expression of ITGB1 protein
Puromycin Aminonucleoside results in increased expression of ITGB1 protein		 CTD PMID:11274237 PMID:12065681 PMID:14559718 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G KDR kinase insert domain receptor affects expression
increases expression
decreases expression		 ISO Puromycin Aminonucleoside affects the expression of KDR mRNA
Puromycin Aminonucleoside results in increased expression of KDR mRNA; Puromycin Aminonucleoside results in increased expression of KDR protein
Puromycin Aminonucleoside results in decreased expression of KDR mRNA		 CTD PMID:11744811 PMID:14752241 PMID:17667850 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KIRREL1 kirre like nephrin family adhesion molecule 1 multiple interactions
decreases expression		 ISO Y 27632 inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of KIRREL1 mRNA] CTD PMID:18367845 NCBI chr 1:157,993,645...158,100,262
Ensembl chr 1:157,993,273...158,100,262 		JBrowse link
G KRT7 keratin 7 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of KRT7 mRNA; Puromycin Aminonucleoside results in decreased expression of KRT7 protein CTD PMID:19617259 NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186 		JBrowse link
G LAMB1 laminin subunit beta 1 multiple interactions
increases expression		 ISO Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB1 mRNA]; FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB1 mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB1 mRNA] CTD PMID:1762292 PMID:9175058 NCBI chr 7:107,923,799...108,003,161
Ensembl chr 7:107,923,799...108,003,213 		JBrowse link
G LAMB2 laminin subunit beta 2 multiple interactions
increases expression		 ISO Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB2 mRNA]; FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB2 mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB2 mRNA] CTD PMID:1762292 PMID:9175058 NCBI chr 3:49,121,114...49,133,050
Ensembl chr 3:49,121,114...49,133,118 		JBrowse link
G LCN2 lipocalin 2 increases secretion ISO Puromycin Aminonucleoside results in increased secretion of LCN2 protein CTD PMID:20438795 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LGALS1 galectin 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of LGALS1 protein CTD PMID:19079321 NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802 		JBrowse link
G LHB luteinizing hormone subunit beta multiple interactions
decreases expression		 ISO [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Estradiol]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Progesterone]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Testosterone]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of STAR mRNA]; CGB3 protein inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; Puromycin Aminonucleoside inhibits the reaction [GNRH1 protein results in increased secretion of LHB protein]
Puromycin Aminonucleoside results in decreased expression of LHB protein		 CTD PMID:12269381 PMID:16574160 NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of MAPK1 protein CTD PMID:14559718 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of MAPK3 protein CTD PMID:14559718 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO Puromycin Aminonucleoside binds to and results in increased activity of MAPK8 protein CTD PMID:15351692 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MDK midkine multiple interactions
decreases expression		 ISO Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of MDK mRNA] CTD PMID:12660332 NCBI chr11:46,380,784...46,383,837
Ensembl chr11:46,380,756...46,383,837 		JBrowse link
G MME membrane metalloendopeptidase decreases expression ISO Puromycin Aminonucleoside results in decreased expression of MME protein CTD PMID:19885019 NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions
increases expression		 ISO FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of MMP2 mRNA] CTD PMID:9175058 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MSN moesin increases expression ISO Puromycin Aminonucleoside results in increased expression of MSN protein CTD PMID:19264907 NCBI chr  X:65,588,377...65,741,931
Ensembl chr  X:65,588,377...65,741,931 		JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I decreases expression ISO Puromycin Aminonucleoside results in decreased expression of COX1 protein CTD PMID:16609681 NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445 		JBrowse link
G MYH10 myosin heavy chain 10 increases expression
affects expression		 ISO Puromycin Aminonucleoside results in increased expression of MYH10 protein
Puromycin Aminonucleoside affects the expression of MYH10 mRNA; Puromycin Aminonucleoside affects the expression of MYH10 protein		 CTD PMID:7671567 PMID:8918620 NCBI chr17:8,474,212...8,630,725
Ensembl chr17:8,474,207...8,631,376 		JBrowse link
G MYH6 myosin heavy chain 6 affects expression ISO Puromycin Aminonucleoside affects the expression of MYH6 mRNA CTD PMID:17457379 NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273 		JBrowse link
G NAPSA napsin A aspartic peptidase increases expression ISO Puromycin Aminonucleoside results in increased expression of NAPSA mRNA; Puromycin Aminonucleoside results in increased expression of NAPSA protein CTD PMID:12501893 NCBI chr19:50,358,477...50,365,639
Ensembl chr19:50,358,472...50,365,830 		JBrowse link
G NDST1 N-deacetylase and N-sulfotransferase 1 decreases expression
affects expression		 ISO Puromycin Aminonucleoside results in decreased expression of NDST1 mRNA
Puromycin Aminonucleoside affects the expression of NDST1 mRNA		 CTD PMID:14966466 NCBI chr 5:150,497,779...150,558,211
Ensembl chr 5:150,485,818...150,558,211 		JBrowse link
G NEBL nebulette decreases expression ISO Puromycin Aminonucleoside results in decreased expression of NEBL mRNA CTD PMID:19617259 NCBI chr10:20,779,973...21,293,050
Ensembl chr10:20,779,973...21,293,011 		JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase decreases expression ISO Puromycin Aminonucleoside results in decreased expression of NEDD4L protein CTD PMID:16020936 NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540 		JBrowse link
G NOS1 nitric oxide synthase 1 multiple interactions
increases expression		 ISO Puromycin Aminonucleoside results in decreased expression of and results in decreased activity of NOS1 protein
Puromycin Aminonucleoside results in increased expression of NOS1 mRNA		 CTD PMID:15039144 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS2 nitric oxide synthase 2 increases expression ISO Puromycin Aminonucleoside results in increased expression of NOS2 mRNA CTD PMID:15039144 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 increases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in increased expression of NOS3 mRNA
Puromycin Aminonucleoside results in decreased expression of and results in decreased activity of NOS3 protein		 CTD PMID:15039144 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NPHS2 NPHS2 stomatin family member, podocin decreases expression
multiple interactions
affects expression		 ISO Puromycin Aminonucleoside results in decreased expression of NPHS2 protein
triptolide inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS2 protein]
Puromycin Aminonucleoside affects the expression of NPHS2 mRNA; Puromycin Aminonucleoside affects the expression of NPHS2 protein		 CTD PMID:12065681 PMID:15363039 PMID:18509322 NCBI chr 1:179,550,539...179,575,948
Ensembl chr 1:179,550,539...179,575,952 		JBrowse link
G NPPA natriuretic peptide A affects metabolic processing
increases response to substance
increases expression
multiple interactions
affects expression		 ISO Puromycin Aminonucleoside affects the metabolism of NPPA protein
Puromycin Aminonucleoside results in increased susceptibility to NPPA protein
Puromycin Aminonucleoside results in increased expression of NPPA mRNA; Puromycin Aminonucleoside results in increased expression of NPPA protein
Puromycin Aminonucleoside inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]
Puromycin Aminonucleoside affects the expression of NPPA protein		 CTD PMID:2526952 PMID:12972712 PMID:15590761 PMID:19885019 PMID:20613715 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345 		JBrowse link
G NPPB natriuretic peptide B affects expression ISO Puromycin Aminonucleoside affects the expression of NPPB mRNA CTD PMID:17457379 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945 		JBrowse link
G NPR1 natriuretic peptide receptor 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of NPR1 mRNA CTD PMID:19885019 NCBI chr 1:153,678,688...153,693,992
Ensembl chr 1:153,678,688...153,693,992 		JBrowse link
G NPR3 natriuretic peptide receptor 3 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of NPR3 mRNA CTD PMID:19885019 NCBI chr 5:32,690,872...32,791,720
Ensembl chr 5:32,689,070...32,791,724 		JBrowse link
G NRF1 nuclear respiratory factor 1 affects expression ISO Puromycin Aminonucleoside affects the expression of NRF1 mRNA CTD PMID:16609681 NCBI chr 7:129,611,720...129,757,076
Ensembl chr 7:129,611,720...129,757,082 		JBrowse link
G OPTN optineurin increases expression ISO
EXP		 Puromycin Aminonucleoside results in increased expression of OPTN protein CTD PMID:25096716 NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,138,308 		JBrowse link
G PDPN podoplanin decreases expression ISO Puromycin Aminonucleoside results in decreased expression of PDPN mRNA; Puromycin Aminonucleoside results in decreased expression of PDPN protein CTD PMID:9327748 PMID:12032185 NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957 		JBrowse link
G PLEKHH2 pleckstrin homology, MyTH4 and FERM domain containing H2 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of PLEKHH2 protein CTD PMID:20588063 NCBI chr 2:43,637,260...43,767,987
Ensembl chr 2:43,637,260...43,767,987 		JBrowse link
G PLN phospholamban increases expression ISO Puromycin Aminonucleoside results in increased expression of PLN mRNA CTD PMID:17457379 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716 		JBrowse link
G PODXL podocalyxin like increases expression
affects metabolic processing		 EXP
ISO		 Puromycin Aminonucleoside results in increased expression of PODXL mRNA; Puromycin Aminonucleoside results in increased expression of PODXL protein
Puromycin Aminonucleoside affects the metabolism of PODXL protein		 CTD PMID:8780404 PMID:11274237 NCBI chr 7:131,500,271...131,556,628
Ensembl chr 7:131,500,262...131,558,217 		JBrowse link
G POLB DNA polymerase beta increases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in increased expression of POLB protein
1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of POLB protein]		 CTD PMID:17035936 NCBI chr 8:42,338,494...42,371,808
Ensembl chr 8:42,338,454...42,371,808 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions
increases expression		 ISO pioglitazone affects the reaction [Puromycin Aminonucleoside results in increased expression of PPARG protein] CTD PMID:16598202 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPP1R12A protein phosphatase 1 regulatory subunit 12A increases phosphorylation
increases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in increased phosphorylation of PPP1R12A protein
Puromycin Aminonucleoside results in increased expression of PPP1R12A protein modified form
Y 27632 inhibits the reaction [Puromycin Aminonucleoside results in increased phosphorylation of PPP1R12A protein]
fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of PPP1R12A protein modified form]		 CTD PMID:16452496 PMID:18367845 NCBI chr12:79,773,563...79,935,460
Ensembl chr12:79,773,563...79,935,460 		JBrowse link
G PRDX3 peroxiredoxin 3 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of PRDX3 protein CTD PMID:19264907 NCBI chr10:119,167,720...119,178,812
Ensembl chr10:119,167,720...119,178,812 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression
affects response to substance
multiple interactions		 ISO Puromycin Aminonucleoside results in increased expression of PTGS2 mRNA; Puromycin Aminonucleoside results in increased expression of PTGS2 protein
PTGS2 protein affects the susceptibility to Puromycin Aminonucleoside
celecoxib inhibits the reaction [Puromycin Aminonucleoside results in increased expression of PTGS2 mRNA]		 CTD PMID:16396944 PMID:17890881 PMID:19194550 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTH parathyroid hormone increases expression ISO Puromycin Aminonucleoside results in increased expression of PTH protein CTD PMID:1328752 NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181 		JBrowse link
G PTK2 protein tyrosine kinase 2 multiple interactions ISO Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of PTK2 protein CTD PMID:14559718 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G PTPRO protein tyrosine phosphatase receptor type O affects expression ISO Puromycin Aminonucleoside affects the expression of PTPRO mRNA; Puromycin Aminonucleoside affects the expression of PTPRO protein CTD PMID:11961407 NCBI chr12:15,322,508...15,598,331
Ensembl chr12:15,322,257...15,602,175 		JBrowse link
G RARA retinoic acid receptor alpha increases expression ISO Puromycin Aminonucleoside results in increased expression of RARA mRNA; Puromycin Aminonucleoside results in increased expression of RARA protein CTD PMID:12660332 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643 		JBrowse link
G RBBP7 RB binding protein 7, chromatin remodeling factor decreases expression ISO Puromycin Aminonucleoside results in decreased expression of RBBP7 protein CTD PMID:15798086 NCBI chr  X:16,844,341...16,870,362
Ensembl chr  X:16,839,283...16,870,362 		JBrowse link
G REN renin multiple interactions
increases expression
affects expression		 ISO Puromycin Aminonucleoside affects the expression of and affects the activity of REN protein; Puromycin Aminonucleoside results in increased expression of and results in increased activity of REN protein
Puromycin Aminonucleoside results in increased expression of REN protein
Puromycin Aminonucleoside affects the expression of REN protein		 CTD PMID:2236972 PMID:2267444 PMID:8446257 PMID:9171944 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
G RHOA ras homolog family member A multiple interactions
increases expression		 ISO fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of RHOA protein] CTD PMID:16452496 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha affects expression
multiple interactions
decreases expression
affects localization		 ISO Puromycin Aminonucleoside affects the expression of SCNN1A mRNA
Puromycin Aminonucleoside results in increased expression of and results in increased localization of SCNN1A protein
Puromycin Aminonucleoside results in decreased expression of SCNN1A mRNA
Puromycin Aminonucleoside affects the localization of SCNN1A protein		 CTD PMID:12653683 PMID:15075188 PMID:16020936 PMID:16267158 NCBI chr12:6,346,847...6,377,359
Ensembl chr12:6,346,843...6,377,730 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta affects expression
increases expression
decreases expression
multiple interactions
affects localization		 ISO Puromycin Aminonucleoside affects the expression of SCNN1B mRNA
Puromycin Aminonucleoside results in increased expression of SCNN1B mRNA
Puromycin Aminonucleoside results in decreased expression of SCNN1B mRNA
Puromycin Aminonucleoside results in increased expression of and results in increased localization of SCNN1B protein
Puromycin Aminonucleoside affects the localization of SCNN1B protein		 CTD PMID:12653683 PMID:15075188 PMID:16020936 PMID:16267158 NCBI chr16:23,278,231...23,381,294
Ensembl chr16:23,278,231...23,381,294 		JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma multiple interactions
increases expression
decreases expression		 ISO Puromycin Aminonucleoside affects the localization of and affects the expression of SCNN1G protein; Puromycin Aminonucleoside results in increased expression of and results in increased localization of SCNN1G protein
Puromycin Aminonucleoside results in increased expression of SCNN1G mRNA
Puromycin Aminonucleoside results in decreased expression of SCNN1G mRNA		 CTD PMID:12653683 PMID:15075188 PMID:16020936 PMID:16267158 NCBI chr16:23,182,745...23,216,883
Ensembl chr16:23,182,745...23,216,883 		JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions
increases expression		 ISO pioglitazone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SERPINE1 mRNA] CTD PMID:16598202 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SLC12A1 solute carrier family 12 member 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of SLC12A1 protein CTD PMID:15075188 NCBI chr15:48,206,302...48,304,078
Ensembl chr15:48,178,438...48,304,078 		JBrowse link
G SLC12A3 solute carrier family 12 member 3 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of SLC12A3 protein CTD PMID:15075188 NCBI chr16:56,865,207...56,915,850
Ensembl chr16:56,865,207...56,915,850 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 affects expression ISO Puromycin Aminonucleoside affects the expression of SLC22A2 mRNA CTD PMID:22005293 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638 		JBrowse link
G SLC29A4 solute carrier family 29 member 4 increases response to substance EXP SLC29A4 results in increased susceptibility to Puromycin Aminonucleoside CTD PMID:19357181 NCBI chr 7:5,282,943...5,306,912
Ensembl chr 7:5,274,369...5,306,912 		JBrowse link
G SLC5A3 solute carrier family 5 member 3 increases expression ISO Puromycin Aminonucleoside results in increased expression of SLC5A3 mRNA CTD PMID:15031335 NCBI chr21:34,073,578...34,106,260
Ensembl chr21:34,073,578...34,106,260 		JBrowse link
G SLC9A3 solute carrier family 9 member A3 multiple interactions
decreases expression
affects expression		 ISO [piperine co-treated with Cimetidine co-treated with Pyruvates] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of SLC9A3 protein]
Puromycin Aminonucleoside affects the expression of SLC9A3 protein		 CTD PMID:12191963 PMID:12806184 PMID:15075188 NCBI chr 5:470,456...524,449
Ensembl chr 5:470,456...524,449 		JBrowse link
G SMAD1 SMAD family member 1 increases expression ISO Puromycin Aminonucleoside results in increased expression of SMAD1 mRNA CTD PMID:17803470 NCBI chr 4:145,480,770...145,559,176
Ensembl chr 4:145,481,194...145,559,176 		JBrowse link
G SOD2 superoxide dismutase 2 affects expression
decreases expression
multiple interactions		 ISO Puromycin Aminonucleoside affects the expression of SOD2 protein
Puromycin Aminonucleoside results in decreased expression of SOD2 protein
[Methylprednisolone co-treated with Puromycin Aminonucleoside] results in increased activity of SOD2 protein		 CTD PMID:1942778 PMID:19264907 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOD3 superoxide dismutase 3 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of SOD3 mRNA CTD PMID:20685819 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842 		JBrowse link
G SPMIP11 sperm microtubule inner protein 11 multiple interactions
decreases expression
affects expression
decreases phosphorylation		 ISO 1,25-dihydroxyvitamin D inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA]; 1,25-dihydroxyvitamin D inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein]; Celecoxib inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA]; fasudil inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein]; Fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA]; Mercuric Chloride promotes the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein]; Puromycin Aminonucleoside affects the expression of and affects the localization of NPHS1 protein; Puromycin Aminonucleoside promotes the reaction [Mercuric Chloride results in decreased expression of NPHS1 mRNA]; Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA]; Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein]; triptolide inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein]
Puromycin Aminonucleoside results in decreased expression of NPHS1; Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA; Puromycin Aminonucleoside results in decreased expression of NPHS1 protein
Puromycin Aminonucleoside affects the expression of NPHS1 mRNA; Puromycin Aminonucleoside affects the expression of NPHS1 protein
Puromycin Aminonucleoside results in decreased phosphorylation of NPHS1 protein		 CTD PMID:10792613 PMID:11012881 PMID:12012391 PMID:12065681 PMID:12386277 More... NCBI chr12:48,727,435...48,771,459
Ensembl chr12:48,727,435...48,765,790 		JBrowse link
G SPP1 secreted phosphoprotein 1 multiple interactions
increases expression		 ISO Drugs, Chinese Herbal inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SPP1 protein]; fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SPP1 mRNA]
Puromycin Aminonucleoside results in increased expression of SPP1 mRNA; Puromycin Aminonucleoside results in increased expression of SPP1 protein		 CTD PMID:14738908 PMID:16452496 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of SRC protein CTD PMID:14559718 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions
decreases expression		 ISO [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of STAR mRNA] CTD PMID:16574160 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G SYNPO synaptopodin decreases expression ISO Puromycin Aminonucleoside results in decreased expression of SYNPO protein CTD PMID:15798086 NCBI chr 5:150,586,010...150,659,207
Ensembl chr 5:150,601,080...150,659,207 		JBrowse link
G TAGLN transgelin increases expression ISO Puromycin Aminonucleoside results in increased expression of TAGLN mRNA; Puromycin Aminonucleoside results in increased expression of TAGLN protein CTD PMID:19617259 NCBI chr11:117,199,294...117,207,465
Ensembl chr11:117,199,370...117,207,464 		JBrowse link
G TEK TEK receptor tyrosine kinase decreases expression ISO Puromycin Aminonucleoside results in decreased expression of TEK mRNA CTD PMID:17667850 NCBI chr 9:27,109,141...27,230,178
Ensembl chr 9:27,109,141...27,230,174 		JBrowse link
G TF transferrin increases expression ISO Puromycin Aminonucleoside results in increased expression of TF mRNA CTD PMID:8413769 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641 		JBrowse link
G TFAM transcription factor A, mitochondrial affects expression ISO Puromycin Aminonucleoside affects the expression of TFAM mRNA CTD PMID:16609681 NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions
increases expression
affects expression		 ISO Celecoxib inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TGFB1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TGFB1 protein]; Masoprocol inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TGFB1 mRNA]
Puromycin Aminonucleoside results in increased expression of TGFB1 mRNA; Puromycin Aminonucleoside results in increased expression of TGFB1 protein
Puromycin Aminonucleoside affects the expression of TGFB1 mRNA		 CTD PMID:9527400 PMID:12397044 PMID:14738908 PMID:19194550 PMID:19594554 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions
increases expression		 ISO FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TIMP1 mRNA] CTD PMID:9175058 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TJP1 tight junction protein 1 multiple interactions
increases expression
affects localization		 ISO Cyclosporine inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TJP1 protein]
Puromycin Aminonucleoside affects the localization of TJP1 protein		 CTD PMID:15744817 PMID:15798086 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
G TNF tumor necrosis factor multiple interactions
increases expression		 ISO Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TNF mRNA] CTD PMID:8384958 PMID:17457379 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type decreases expression ISO Puromycin Aminonucleoside results in decreased expression of TNNC1 mRNA CTD PMID:19617259 NCBI chr 3:52,451,100...52,454,041
Ensembl chr 3:52,451,100...52,454,041 		JBrowse link
G TP53 tumor protein p53 multiple interactions
increases expression		 ISO 1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TP53 protein]; Melatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TP53 protein]
Puromycin Aminonucleoside results in increased expression of TRP53 protein
1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TRP53 protein]; Dexamethasone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TRP53 protein]		 CTD PMID:14993511 PMID:15113391 PMID:15987750 PMID:16152783 PMID:17035936 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TTR transthyretin increases expression ISO Puromycin Aminonucleoside results in increased expression of TTR protein CTD PMID:19264907 NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833 		JBrowse link
G UCP3 uncoupling protein 3 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of UCP3 protein CTD PMID:19264907 NCBI chr11:74,000,277...74,009,085
Ensembl chr11:74,000,277...74,009,085 		JBrowse link
G VCAN versican decreases expression EXP Puromycin Aminonucleoside results in decreased expression of VCAN mRNA; Puromycin Aminonucleoside results in decreased expression of VCAN protein CTD PMID:15585670 NCBI chr 5:83,471,744...83,582,302
Ensembl chr 5:83,471,618...83,582,303 		JBrowse link
G VCL vinculin affects localization
increases expression		 ISO Puromycin Aminonucleoside affects the localization of VCL protein
Puromycin Aminonucleoside results in increased expression of VCL mRNA; Puromycin Aminonucleoside results in increased expression of VCL protein		 CTD PMID:19617259 NCBI chr10:73,998,116...74,121,363
Ensembl chr10:73,995,193...74,121,363 		JBrowse link
G VEGFA vascular endothelial growth factor A affects expression
increases expression		 ISO Puromycin Aminonucleoside affects the expression of VEGFA mRNA
Puromycin Aminonucleoside results in increased expression of VEGFA protein		 CTD PMID:11744811 PMID:14752241 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VIM vimentin multiple interactions
increases expression		 ISO fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of VIM mRNA] CTD PMID:16452496 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G WTIP WT1 interacting protein affects localization ISO Puromycin Aminonucleoside affects the localization of WTIP protein CTD PMID:15798086 NCBI chr19:34,481,758...34,512,304
Ensembl chr19:34,481,758...34,512,304 		JBrowse link
G XCL1 X-C motif chemokine ligand 1 affects expression ISO Puromycin Aminonucleoside affects the expression of XCL1 mRNA CTD PMID:10867541 NCBI chr 1:168,576,605...168,582,069
Ensembl chr 1:168,576,605...168,582,069 		JBrowse link
G XDH xanthine dehydrogenase increases activity
multiple interactions		 ISO Puromycin Aminonucleoside results in increased activity of XDH
[Tungsten co-treated with Puromycin Aminonucleoside] results in decreased activity of XDH protein		 CTD PMID:7583048 PMID:11041286 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26046
    role 25962
      biological role 25941
        biochemical role 25177
          metabolite 25107
            fundamental metabolite 15685
              purine 7177
                9H-purine 7015
                  adenine 1049
                    adenosines 793
                      3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine 191
Path 2
Term Annotations click to browse term
  CHEBI ontology 26046
    subatomic particle 26021
      composite particle 26021
        hadron 26021
          baryon 26021
            nucleon 26021
              atomic nucleus 26021
                atom 26021
                  main group element atom 25846
                    p-block element atom 25846
                      carbon group element atom 25443
                        carbon atom 25401
                          organic molecular entity 25401
                            heteroorganic entity 24779
                              organochalcogen compound 24391
                                organooxygen compound 24069
                                  carbohydrates and carbohydrate derivatives 16793
                                    carbohydrate 16793
                                      carbohydrate derivative 15667
                                        glycosyl compound 13730
                                          N-glycosyl compound 6132
                                            nucleoside 5975
                                              ribonucleoside 1157
                                                purine ribonucleoside 813
                                                  adenosines 793
                                                    3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine 191
paths to the root