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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731579 Species: Homo sapiens RGD Object: Gene Symbol: HMGCR Name: 3-hydroxy-3-methylglutaryl-CoA reductase

Acc ID: CHEBI:42839 Term: 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine Definition: Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring. CasRN: 58-60-6 Chemical ID: MESH:D011692

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases activity	ISO	RGD:2803	6480464	CTD	Puromycin Aminonucleoside results in increased activity of HMGCR protein	PMID:3794548