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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347215 Species: Homo sapiens RGD Object: Gene Symbol: TIMP1 Name: TIMP metallopeptidase inhibitor 1

Acc ID: CHEBI:42839 Term: 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine Definition: Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring. CasRN: 58-60-6 Chemical ID: MESH:D011692

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:621675	6480464	CTD	FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TIMP1 mRNA]	PMID:9175058
increases expression	ISO	RGD:621675	6480464	CTD	Puromycin Aminonucleoside results in increased expression of TIMP1 mRNA	PMID:9175058