| 8939010 | Star | steroidogenic acute regulatory protein | ENCODES a protein that exhibits cholesterol binding (ortholog); cholesterol transfer activity (ortholog); INVOLVED IN bile acid biosynthetic process (ortholog); C21-steroid hormone biosynthetic process (ortholog); cellular response to alkaloid (ortholog); PARTICIPATES IN aldosterone biosynthetic pat hway; cortisol biosynthetic pathway; estradiol biosynthetic pathway; ASSOCIATED WITH Cardiomegaly (ortholog); congenital adrenal hyperplasia (ortholog); Disorders of Environmental Origin (ortholog); FOUND IN mitochondrial crista (ortholog); mitochondrial outer membrane (ortholog); mitochondrion (ortholog) | NW_004955463 | 13760089 | 13765245 | Chinchilla | 105 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 8784714 | Stard3 | StAR related lipid transfer domain containing 3 | ENCODES a protein that exhibits cholesterol binding (ortholog); cholesterol transfer activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cholesterol transport (ortholog); progesterone biosynthetic process (ortholog); vesicle tethering to endoplasmic reticulum (ortholog); A SSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); endoplasmic reticulum-endosome membrane contact site (ortholog); endosome (ortholog) | NW_004955451 | 14395088 | 14412041 | Chinchilla | 25 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 8763831 | Stard4 | StAR related lipid transfer domain containing 4 | ENCODES a protein that exhibits cholesterol binding (ortholog); cholesterol transfer activity (ortholog); INVOLVED IN cholesterol import (ortholog); cholesterol transport involved in cholesterol storage (ortholog); intracellular cholesterol transport (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog) | NW_004955418 | 3637390 | 3652054 | Chinchilla | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 9061876 | Stard5 | StAR related lipid transfer domain containing 5 | ENCODES a protein that exhibits bile acid binding (ortholog); cholesterol binding (ortholog); cholesterol transfer activity (ortholog); INVOLVED IN cholesterol import (ortholog) | NW_004955416 | 11989572 | 12000226 | Chinchilla | 4 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 8917771 | Stard6 | StAR related lipid transfer domain containing 6 | | NW_004955402 | 38909124 | 38929932 | Chinchilla | | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 8712066 | Stard7 | StAR related lipid transfer domain containing 7 | ENCODES a protein that exhibits molecular carrier activity (ortholog); phosphatidylcholine transfer activity (ortholog); INVOLVED IN establishment of skin barrier (ortholog); inflammatory response (ortholog); intermembrane phospholipid transfer (ortholog); ASSOCIATED WITH familial adult myoclonic ep ilepsy 2 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial intermembrane space (ortholog) | NW_004955470 | 3771410 | 3790667 | Chinchilla | 20 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 8952759 | Stard8 | StAR related lipid transfer domain containing 8 | ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog) | NW_004955475 | 8203624 | 8278319 | Chinchilla | 2 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 9050044 | Stard9 | StAR related lipid transfer domain containing 9 | ENCODES a protein that exhibits microtubule binding (ortholog); microtubule motor activity (ortholog); INVOLVED IN spindle assembly (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); bipolar disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN centriole (ortholog); cyto plasm (ortholog); nucleus (ortholog) | NW_004955416 | 9276026 | 9393842 | Chinchilla | 9 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 8939353 | LOC102003534 | stAR-related lipid transfer protein 4 pseudogene | | NW_004955474 | 6726759 | 6727385 | Chinchilla | | name | gene, pseudo, MODEL [RefSeq] |
| 9065747 | Stard10 | StAR related lipid transfer domain containing 10 | INVOLVED IN bile acid secretion (ortholog); positive regulation of peroxisome proliferator activated receptor signaling pathway (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytosol (ortholog); intercellular canaliculus (ortholog); membrane (ortholog) | NW_004955414 | 18641346 | 18664886 | Chinchilla | 8 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 8752283 | Stard13 | StAR related lipid transfer domain containing 13 | INVOLVED IN endothelial cell migration (ortholog); endothelial tube lumen extension (ortholog); negative regulation of cell migration involved in sprouting angiogenesis (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Experimental Liver Cirrhosis (ortholog) | NW_004955431 | 12221980 | 12732894 | Chinchilla | 10 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 8826205 | Stard3nl | STARD3 N-terminal like | ENCODES a protein that exhibits cholesterol binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN vesicle tethering to endoplasmic reticulum (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); endoplasmic reticulum-endosome membrane contact site (ortholog); endoso me (ortholog) | NW_004955460 | 5364546 | 5423330 | Chinchilla | 12 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 8868064 | Alb | albumin | ENCODES a protein that exhibits DNA binding (ortholog); enterobactin binding (ortholog); enzyme binding (ortholog); INVOLVED IN bilirubin transport (ortholog); cellular response to calcium ion starvation (ortholog); cellular response to star 700;'>starvation (ortholog); PARTICIPATES IN forkhead class A signaling pathway; organophosphate response pathway; ASSOCIATED WITH suppurative otitis media; Acute Coronary Syndrome (ortholog); acute kidney failure (ortholog); FOUND IN extracellular space; basement membrane (ortholog); cytoplasm (ortholog) | NW_004955447 | 9327 | 21212 | Chinchilla | 183 | description | gene, protein-coding, MODEL [RefSeq] |
| 8835135 | Atf4 | activating transcription factor 4 | ENCODES a protein that exhibits cAMP response element binding (ortholog); cAMP response element binding protein binding (ortholog); DNA binding (ortholog); INVOLVED IN bone mineralization (ortholog); cellular response to amino acid starvation (ortholog); cellula r response to glucose starvation (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; ASSOCIATED WITH borna disease (ortholog); Hypoxia (ortholog); invasive ductal carcinoma (ortholog); FOUND IN ATF1-ATF4 transcription factor complex (ortholog); ATF4-CREB1 transcription factor complex (ortholog); centrosome (ortholog) | NW_004955413 | 25406589 | 25408727 | Chinchilla | 173 | description | gene, protein-coding, MODEL [RefSeq] |
| 8809845 | Eif2ak4 | eukaryotic translation initiation factor 2 alpha kinase 4 | ENCODES a protein that exhibits eukaryotic translation initiation factor 2alpha kinase activity (ortholog); protein kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog) ; cellular response to cold (ortholog); cellular response to starvation (ortholog); ASSOCIATED WITH amino acid metabolic disorder (ortholog); genetic disease (ortholog); hair disease (ortholog); FOUND IN cytoplasm (ortholog) | NW_004955416 | 6897897 | 7005602 | Chinchilla | 63 | description | gene, protein-coding, MODEL [RefSeq] |
| 8757659 | Flcn | folliculin | ENCODES a protein that exhibits enzyme binding (ortholog); enzyme inhibitor activity (ortholog); GTPase activator activity (ortholog); INVOLVED IN cell-cell junction assembly (ortholog); cellular response to amino acid starvation (ortholog); cellular response to starvation (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Birt-Hogg-Dube syndrome (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); colon carcinoma (ortholog); FOUND IN cell-cell contact zone (ortholog); centrosome (ortholog); cilium (ortholog) | NW_004955577 | 672774 | 694140 | Chinchilla | 114 | description | gene, protein-coding, MODEL [RefSeq] |
| 8751282 | Itfg2 | integrin alpha FG-GAP repeat containing 2 | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to glucose starvation (ortholog); germinal center B cell differentiation (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog ); FOUND IN cytosol (ortholog); KICSTOR complex (ortholog); lysosomal membrane (ortholog) | NW_004955429 | 18356642 | 18372928 | Chinchilla | 10 | description | gene, protein-coding, MODEL [RefSeq] |
| 9008714 | Kics2 | KICSTOR subunit 2 | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to glucose starvation (ortholog); negative regulation of TORC1 signaling (ortholog); ASSOCIATED WITH autosomal recessive intellectual devel opmental disorder 83 (ortholog); polycystic ovary syndrome (ortholog); FOUND IN KICSTOR complex (ortholog) | NW_004955458 | 11027550 | 11048563 | Chinchilla | 9 | description | gene, protein-coding, MODEL [RefSeq] |
| 8882025 | Kptn | kaptin, actin binding protein | ENCODES a protein that exhibits actin filament binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to glucose starvation (ortholog); negative regulation of TORC1 signaling (ortholog); ASSOCIATED WITH autosomal recessive intellectual developmental disorder 41 (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN filamentous actin (ortholog); KICSTOR complex (ortholog); lamellipodium (ortholog) | NW_004955574 | 1321356 | 1329132 | Chinchilla | 13 | description | gene, protein-coding, MODEL [RefSeq] |
| 8708155 | Rragb | Ras related GTP binding B | ENCODES a protein that exhibits GTP binding (ortholog); GTPase binding (ortholog); guanyl ribonucleotide binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to amino acid stimulus (ortholog); cellular response to leucine starvation (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (ortholog); Gtr1-Gtr2 GTPase complex (ortholog); lysosome (ortholog) | NW_004955475 | 2662969 | 2692253 | Chinchilla | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 8870975 | Sesn3 | sestrin 3 | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to amino acid stimulus (ortholog); cellular response to glucose starvation (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUN D IN cytoplasm (ortholog); GATOR2 complex (ortholog); TORC2 complex (ortholog) | NW_004955412 | 100335 | 125395 | Chinchilla | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 8964463 | Szt2 | SZT2 subunit of KICSTOR complex | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to glucose starvation (ortholog); central nervous system development (ortholog); ASSOCIATED WITH benign epilepsy with centrotemporal spikes (ortholog); cryptorchidism (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN GATOR1 complex (ortholog); GATOR2 complex (ortholog); KICSTOR complex (ortholog) | NW_004955537 | 2968839 | 3017863 | Chinchilla | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 8774020 | Tfeb | transcription factor EB | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN antibacterial innate immune response (ortholog); cellular response to amino acid star 'font-weight:700;'>starvation (ortholog); cellular response to starvation (ortholog); ASSOCIATED WITH Nerve Degeneration (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); lysosomal membrane (ortholog) | NW_004955437 | 8102241 | 8141001 | Chinchilla | 43 | description | gene, protein-coding, MODEL [RefSeq] |
| 8999356 | Stbd1 | starch binding domain 1 | ENCODES a protein that exhibits cargo receptor activity (ortholog); enzyme binding (ortholog); glycogen binding (ortholog); INVOLVED IN glycogen catabolic process (ortholog); glycophagy (ortholog); lysosomal transport (ortholog); FOUND IN endoplasmic reticulum (ortholog); membrane (ortholog); perinu clear region of cytoplasm (ortholog) | NW_004955433 | 1036265 | 1038652 | Chinchilla | 23 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 8864597 | LOC102003661 | starch-binding domain-containing protein 1-like | | NW_004955421 | 9799138 | 9801408 | Chinchilla | | name | gene, protein-coding, MODEL [RefSeq] |
| 8854707 | Mfsd11 | major facilitator superfamily domain containing 11 | INVOLVED IN response to food (ortholog); response to starvation (ortholog) | NW_004955506 | 5534560 | 5568765 | Chinchilla | 3 | description | gene, protein-coding, MODEL [RefSeq] |
| 8966216 | Gys2 | glycogen synthase 2 | ENCODES a protein that exhibits alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (ortholog); D-glucose binding (ortholog); INVOLVED IN glycogen biosynthetic process (ortholog); glycogen metabolic process (ortholog); response to glucose (ortholog); PARTICIPATES IN congenital sucrase- isomaltase deficiency pathway; glycogen biosynthetic pathway; glycogen metabolic pathway; ASSOCIATED WITH genetic disease (ortholog); glycogen storage disease (ortholog); Glycogen Storage Disease 0, Liver (ortholog); FOUND IN cell cortex (ortholog); cortical actin cytoskeleton (ortholog); cytoplasm (ortholog) | NW_004955413 | 17182342 | 17240180 | Chinchilla | 39 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 8752712 | Gys1 | glycogen synthase 1 | ENCODES a protein that exhibits alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (ortholog); D-glucose binding (ortholog); glycogen synthase activity, transferring glucose-1-phosphate (ortholog); INVOLVED IN glycogen biosynthetic process (ortholog); glycogen metabolic process (ortho log); heart development (ortholog); PARTICIPATES IN glycogen biosynthetic pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; ASSOCIATED WITH cardiovascular system disease (ortholog); genetic disease (ortholog); Glycogen Storage Disease 0, Muscle (ortholog); FOUND IN catalytic complex (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955559 | 1674969 | 1690098 | Chinchilla | 38 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 8883340 | Acp5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity (ortholog); ferric iron binding (ortholog); ferrous iron binding (ortholog); INVOLVED IN bone morphogenesis (ortholog); bone resorption (ortholog); cellular response to zinc ion starvation (ortholog); ASS OCIATED WITH Alveolar Bone Loss (ortholog); Combined Immunodeficiency with Autoimmunity and Spondylometaphyseal Dysplasia (ortholog); Desbuquois dysplasia (ortholog); FOUND IN extracellular space (ortholog); lysosome (ortholog) | NW_004955495 | 2418113 | 2421181 | Chinchilla | 47 | description | gene, protein-coding, MODEL [RefSeq] |
| 8996353 | Ambra1 | autophagy and beclin 1 regulator 1 | ENCODES a protein that exhibits GTPase binding (ortholog); protein phosphatase activator activity (ortholog); protein phosphatase binding (ortholog); INVOLVED IN autophagosome assembly (ortholog); autophagy (ortholog); cellular response to starvation (ortholog); PARTICIPATES IN inositol metabolic pathway; mitochondrial autophagy pathway; phosphoinositide metabolic pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); esophageal atresia (ortholog); multiple system atrophy (ortholog); FOUND IN axoneme (ortholog); Cul4-RING E3 ubiquitin ligase complex (ortholog); cytoplasm (ortholog) | NW_004955422 | 1455392 | 1644368 | Chinchilla | 69 | description | gene, protein-coding, MODEL [RefSeq] |
| 8991138 | Atf3 | activating transcription factor 3 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); endoplasmic reticulum unfolded protein response (ortholog); gluconeogenesis (ortholog); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); cardiomyopathy (ortholog); Experimental Arthritis (ortholog); FOUND IN CHOP-ATF3 complex (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | NW_004955406 | 4875672 | 4889173 | Chinchilla | 73 | description | gene, protein-coding, MODEL [RefSeq] |
| 8860648 | Atg4b | autophagy related 4B cysteine peptidase | ENCODES a protein that exhibits cysteine-type endopeptidase activity (ortholog); cysteine-type peptidase activity (ortholog); endopeptidase activity (ortholog); INVOLVED IN autophagosome assembly (ortholog); autophagy (ortholog); cellular response to starvation (ortholog); PARTICIPATES IN autophagy pathway; FOUND IN autophagosome membrane (ortholog); cytoplasm (ortholog) | NW_004955542 | 164969 | 192498 | Chinchilla | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 8967050 | Atxn3 | ataxin 3 | ENCODES a protein that exhibits ATPase binding (ortholog); cysteine-type deubiquitinase activity (ortholog); histone deacetylase activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); cellular response to amino acid starvation (ortholog); c ellular response to heat (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH atrophic muscular disease (ortholog); Cataplexy (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum membrane (ortholog) | NW_004955438 | 14405415 | 14443457 | Chinchilla | 68 | description | gene, protein-coding, MODEL [RefSeq] |
| 9044936 | Bmt2 | base methyltransferase of 25S rRNA 2 homolog | ENCODES a protein that exhibits protein-containing complex binding (ortholog); S-adenosyl-L-methionine binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to methionine (ortholog); positive regulation of TORC1 signaling (ortholog) | NW_004955432 | 19046121 | 19107178 | Chinchilla | 6 | description | gene, protein-coding, MODEL [RefSeq] |
| 8824667 | Cadps2 | calcium dependent secretion activator 2 | INVOLVED IN cellular response to starvation (ortholog); hematopoietic stem cell homeostasis (ortholog); positive regulation of exocytosis (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); Chemical and Drug Induced Liv er Injury (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); cilium (ortholog) | NW_004955479 | 3961877 | 4485710 | Chinchilla | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 8854725 | Castor1 | cytosolic arginine sensor for mTORC1 subunit 1 | ENCODES a protein that exhibits arginine binding (ortholog); identical protein binding (ortholog); molecular sensor activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to L-arginine (ortholog); negative regul ation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (ortholog); GATOR2 complex (ortholog) | NW_004955455 | 4530842 | 4535358 | Chinchilla | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 8830329 | Cdkn1a | cyclin dependent kinase inhibitor 1A | ENCODES a protein that exhibits cyclin binding (ortholog); cyclin-dependent protein serine/threonine kinase inhibitor activity (ortholog); molecular function activator activity (ortholog); INVOLVED IN animal organ regeneration (ortholog); cellular response to amino acid star '>starvation (ortholog); cellular response to cell-matrix adhesion (ortholog); PARTICIPATES IN G1/S transition pathway; Notch signaling pathway; nuclear factor, erythroid 2 like 2 signaling pathway; ASSOCIATED WITH acoustic neuroma (ortholog); Acute Experimental Pancreatitis (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN cyclin-dependent protein kinase holoenzyme complex (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955437 | 6254638 | 6261278 | Chinchilla | 283 | description | gene, protein-coding, MODEL [RefSeq] |
| 8705713 | Chka | choline kinase alpha | ENCODES a protein that exhibits ATP binding (ortholog); choline binding (ortholog); choline kinase activity (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); choline metabolic process (ortholog); ethanolamine metabolic process (ortholog ); PARTICIPATES IN glycerophospholipid metabolic pathway; ASSOCIATED WITH colon adenoma (ortholog); colon cancer (ortholog); epilepsy (ortholog); FOUND IN cytosol (ortholog); lipid droplet (ortholog) | NW_004955422 | 17710981 | 17766256 | Chinchilla | 30 | description | gene, protein-coding, MODEL [RefSeq] |
| 9052505 | Clec16a | C-type lectin domain containing 16A | INVOLVED IN cellular response to starvation (ortholog); mitophagy (ortholog); negative regulation of autophagosome maturation (ortholog); ASSOCIATED WITH Addison's disease (ortholog); immunoglobulin alpha deficiency (ortholog); Meniere's disease (ortholog); FOUN D IN cytosol (ortholog); endolysosome membrane (ortholog); Golgi apparatus (ortholog) | NW_004955442 | 7369616 | 7584052 | Chinchilla | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 8731983 | Cpeb4 | cytoplasmic polyadenylation element binding protein 4 | ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to decreased oxygen levels (ortholog); cellular response to glucose starvation (ortholog); ASSOCIATED WITH liver cirrhosis (ortholog); portal hypertension (ortholog); primary biliary cholangitis (ortholog); FOUND IN cytoplasm (ortholog); dendrite (ortholog); endoplasmic reticulum (ortholog) | NW_004955408 | 26535281 | 26597317 | Chinchilla | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 8865746 | Depdc5 | DEP domain containing 5, GATOR1 subcomplex subunit | ENCODES a protein that exhibits protein-containing complex binding (ortholog); small GTPase binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling p athway; ASSOCIATED WITH autosomal dominant nocturnal frontal lobe epilepsy (ortholog); benign epilepsy with centrotemporal spikes (ortholog); Developmental and Epileptic Encephalopathy 111 (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); cytosol (ortholog); GATOR1 complex (ortholog) | NW_004955455 | 5881631 | 6005514 | Chinchilla | 37 | description | gene, protein-coding, MODEL [RefSeq] |
| 8732073 | Dnajc15 | DnaJ heat shock protein family (Hsp40) member C15 | INVOLVED IN cellular response to starvation (ortholog); negative regulation of mitochondrial electron transport, NADH to ubiquinone (ortholog); negative regulation of protein-containing complex assembly (ortholog); ASSOCIATED WITH melanoma (ortholog); FOUND IN m itochondrial inner membrane (ortholog); mitochondrion (ortholog) | NW_004955518 | 941610 | 1016097 | Chinchilla | 9 | description | gene, protein-coding, MODEL [RefSeq] |
| 8984999 | Dsc2 | desmocollin 2 | INVOLVED IN bundle of His cell-Purkinje myocyte adhesion involved in cell communication (ortholog); cardiac muscle cell-cardiac muscle cell adhesion (ortholog); cellular response to starvation (ortholog); ASSOCIATED WITH acute myocardial infarction (ortholog); a rrhythmogenic right ventricular cardiomyopathy (ortholog); arrhythmogenic right ventricular dysplasia 1 (ortholog); FOUND IN adherens junction (ortholog); cytoplasmic vesicle (ortholog); desmosome (ortholog) | NW_004955402 | 18465631 | 18496948 | Chinchilla | 51 | description | gene, protein-coding, MODEL [RefSeq] |
| 8996982 | Ehmt2 | euchromatic histone lysine methyltransferase 2 | ENCODES a protein that exhibits C2H2 zinc finger domain binding (ortholog); H1-4K26 methyltransferase activity (ortholog); histone H3K27 methyltransferase activity (ortholog); INVOLVED IN behavioral response to cocaine (ortholog); cellular response to cocaine (ortholog); cellular response to star tyle='font-weight:700;'>starvation (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); alopecia areata (ortholog); FOUND IN chromatin (ortholog); nuclear speck (ortholog); nucleolus (ortholog) | NW_004955437 | 396736 | 411144 | Chinchilla | 106 | description | gene, protein-coding, MODEL [RefSeq] |
| 8904594 | Eif2ak2 | eukaryotic translation initiation factor 2 alpha kinase 2 | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); eukaryotic translation initiation factor 2alpha kinase activity (ortholog); identical protein binding (ortholog); INVOLVED IN antiviral innate immune response (ortholog); cellular response to amino acid star 700;'>starvation (ortholog); endoplasmic reticulum unfolded protein response (ortholog); PARTICIPATES IN ceramide signaling pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); Cardiovirus Infections (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); perinuclear region of cytoplasm (ortholog) | NW_004955441 | 4908318 | 4944343 | Chinchilla | 103 | description | gene, protein-coding, MODEL [RefSeq] |
| 8963522 | Eif2s1 | eukaryotic translation initiation factor 2 subunit alpha | ENCODES a protein that exhibits cap-dependent translation initiation factor activity (ortholog); IRES-mediated translation initiation factor activity (ortholog); ribosome binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cell ular response to heat (ortholog); cellular response to oxidative stress (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH alcohol-associated liver disease (ortholog); Alzheimer's disease (ortholog); Brain Hypoxia-Ischemia (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); cytosol (ortholog) | NW_004955466 | 2838785 | 2855443 | Chinchilla | 74 | description | gene, protein-coding, MODEL [RefSeq] |
| 8977964 | Elapor1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | INVOLVED IN autophagosome assembly (ortholog); cellular response to starvation (ortholog); positive regulation of autophagosome assembly (ortholog); FOUND IN late endosome (ortholog); lysosome (ortholog); plasma membrane (ortholog) | NW_004955435 | 12531651 | 12626969 | Chinchilla | 10 | description | gene, protein-coding, MODEL [RefSeq] |
| 8807231 | Epm2aip1 | EPM2A interacting protein 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN positive regulation of glycogen (starch) synthase activity (ortholog); positive regulation of glycogen biosynthetic process (ortholog); response to insulin (ortholog); ASSOCIATED W ITH hereditary nonpolyposis colorectal cancer type 2 (ortholog); Lynch syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of endoplasmic reticulum membrane (ortholog); nucleus (ortholog) | NW_004955421 | 3882486 | 3889851 | Chinchilla | 16 | description | gene, protein-coding, MODEL [RefSeq] |
| 10300641 | Fads1 | fatty acid desaturase 1 | ENCODES a protein that exhibits acyl-CoA (8-3)-desaturase activity (ortholog); acyl-CoA 6-desaturase activity (ortholog); omega-6 fatty acid desaturase activity (ortholog); INVOLVED IN arachidonate metabolic process (ortholog); cellular response to starvation (o rtholog); fatty acid biosynthetic process (ortholog); PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; ASSOCIATED WITH Cardiac Fibrosis (ortholog); Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog) | NW_004955511 | 5908394 | 5915764 | Chinchilla | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 8840067 | Fbxo22 | F-box protein 22 | INVOLVED IN cellular response to starvation (ortholog); nucleocytoplasmic transport (ortholog); positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Tayoun-Maawali syndrome (ortholog); FOUND IN cytoplasm (o rtholog); nucleus (ortholog) | NW_004955450 | 1152383 | 1171257 | Chinchilla | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 8965590 | Fnip1 | folliculin interacting protein 1 | ENCODES a protein that exhibits ATPase inhibitor activity (ortholog); enzyme activator activity (ortholog); enzyme binding (ortholog); INVOLVED IN B cell differentiation (ortholog); cellular response to starvation (ortholog); immature B cell differentiation (ort holog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH genetic disease (ortholog); immunodeficiency 93 (ortholog); Wolff-Parkinson-White syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); FNIP-folliculin RagC/D GAP (ortholog) | NW_004955408 | 3117258 | 3238223 | Chinchilla | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 8890093 | Foxa3 | forkhead box A3 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to starvation (ortholog); hematopoietic stem cell homeostasis (ortholog); intrac ellular glucose homeostasis (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); Prostatic Neoplasms (ortholog); FOUND IN nucleus (ortholog) | NW_004955574 | 293344 | 301955 | Chinchilla | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 8965113 | Gas2l1 | growth arrest specific 2 like 1 | ENCODES a protein that exhibits cytoskeletal anchor activity (ortholog); microtubule binding (ortholog); INVOLVED IN cellular response to starvation (ortholog); microtubule bundle formation (ortholog); negative regulation of microtubule depolymerization (ortholo g); ASSOCIATED WITH acute myeloid leukemia (ortholog); FOUND IN actin filament (ortholog); cytoplasm (ortholog); microtubule (ortholog) | NW_004955455 | 3613092 | 3618476 | Chinchilla | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 9044765 | Gck | glucokinase | ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); D-glucose binding (ortholog); INVOLVED IN calcium ion import (ortholog); carbohydrate phosphorylation (ortholog); cellular response to glucose starvation (ortholog); PARTICIPATES IN congenital sucrase-isomaltase deficiency pathway; forkhead class A signaling pathway; galactokinase deficiency pathway; ASSOCIATED WITH Bone Marrow Failure Syndrome 2 (ortholog); Congenital Hyperinsulinism (ortholog); coronary artery disease (ortholog); FOUND IN actin filament (ortholog); basal cortex (ortholog); cell cortex (ortholog) | NW_004955456 | 7784269 | 7838260 | Chinchilla | 179 | description | gene, protein-coding, MODEL [RefSeq] |
| 8760666 | Gcn1 | GCN1 activator of EIF2AK4 | ENCODES a protein that exhibits molecular adaptor activity (ortholog); protein serine/threonine kinase activator activity (ortholog); stalled ribosome sensor activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); GCN2-mediated si gnaling (ortholog); protein-RNA covalent cross-linking repair (ortholog); ASSOCIATED WITH fetal akinesia deformation sequence syndrome 1 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); cytosolic ribosome (ortholog) | NW_004955455 | 11416222 | 11474791 | Chinchilla | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 9054336 | Glul | glutamate-ammonia ligase | ENCODES a protein that exhibits ATP binding (ortholog); dynein light chain binding (ortholog); glutamate binding (ortholog); INVOLVED IN ammonia assimilation cycle (ortholog); cell population proliferation (ortholog); cellular response to starvation (ortholog); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; glutamic acid/glutamate metabolic pathway; homocarnosinosis pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Carotid Atherosclerosis (ortholog); congenital glutamine deficiency (ortholog); FOUND IN axon terminus (ortholog); cell body (ortholog); cell projection (ortholog) | NW_004955406 | 21266383 | 21274546 | Chinchilla | 97 | description | gene, protein-coding, MODEL [RefSeq] |
| 8840562 | Gpr155 | G protein-coupled receptor 155 | ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to cholesterol (ortholog); cognition (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Hepatomegaly (orth olog); FOUND IN lysosomal membrane (ortholog) | NW_004955449 | 889657 | 930146 | Chinchilla | 8 | description | gene, protein-coding, MODEL [RefSeq] |
| 8715762 | Higd1a | HIG1 hypoxia inducible domain family member 1A | INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to hypoxia (ortholog); negative regulation of apoptotic process (ortholog); FOUND IN membrane (ortholog); mitochondrial inner membrane (ortholog); mitochondrion (ortholog) | NW_004955420 | 28040320 | 28050723 | Chinchilla | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 9030277 | Hnrnpa1 | heterogeneous nuclear ribonucleoprotein A1 | ENCODES a protein that exhibits DNA binding (ortholog); DNA/DNA annealing activity (ortholog); G-rich strand telomeric DNA binding (ortholog); INVOLVED IN alternative mRNA splicing, via spliceosome (ortholog); cellular response to epidermal growth factor stimulus (ortholog); cellular response to glu cose starvation (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); amyotrophic lateral sclerosis type 20 (ortholog); Animal Disease Models (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); cytoplasm (ortholog); nucleoplasm (ortholog) | NW_004955458 | 1530163 | 1536874 | Chinchilla | 85 | description | gene, protein-coding, MODEL [RefSeq] |
| 8764228 | Hnrnpl | heterogeneous nuclear ribonucleoprotein L | ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog); mRNA CDS binding (ortholog); pre-mRNA intronic binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); circadian rhythm (ortholog); negative regulation of DNA-template d transcription (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH brain cancer (ortholog); Breast Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); nucleoplasm (ortholog) | NW_004955468 | 668177 | 683540 | Chinchilla | 42 | description | gene, protein-coding, MODEL [RefSeq] |
| 8716485 | Ifi16 | interferon gamma inducible protein 16 | ENCODES a protein that exhibits double-stranded DNA binding (ortholog); identical protein binding (ortholog); transcription coregulator activity (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to interferon-alpha (or tholog); cellular response to interferon-beta (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nuclear inclusion body (ortholog) | NW_004955468 | 10828726 | 10845853 | Chinchilla | 47 | description | gene, protein-coding, MODEL [RefSeq] |
| 8989934 | Impact | impact RWD domain protein | ENCODES a protein that exhibits actin binding (ortholog); protein sequestering activity (ortholog); ribosome binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); GCN2-mediated signaling (ortholog); intracellular signal transduct ion (ortholog); FOUND IN cytoplasm (ortholog) | NW_004955402 | 12752748 | 12781238 | Chinchilla | 16 | description | gene, protein-coding, MODEL [RefSeq] |
| 8768844 | Kat5 | lysine acetyltransferase 5 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); histone acetyltransferase activity (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to estradiol stimulus (ortholog); cellular response to glucose star nt-weight:700;'>starvation (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); breast cancer (ortholog); iron deficiency anemia (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955422 | 19557498 | 19565044 | Chinchilla | 139 | description | gene, protein-coding, MODEL [RefSeq] |
| 8810076 | Klf10 | KLF transcription factor 10 | ENCODES a protein that exhibits core promoter sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN bone mineralization (ortholog); c ellular response to endothelin (ortholog); cellular response to starvation (ortholog); FOUND IN nucleus (ortholog) | NW_004955417 | 27165146 | 27168604 | Chinchilla | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 8913213 | Lamp2 | lysosomal associated membrane protein 2 | ENCODES a protein that exhibits enzyme binding (ortholog); ion channel inhibitor activity (ortholog); protein domain specific binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagy (ortholog); cellular response to starvation (ortholog); P ARTICIPATES IN autophagy pathway; chaperone mediated autophagy pathway; ASSOCIATED WITH Acute Experimental Pancreatitis (ortholog); cardiomyopathy (ortholog); cholestasis (ortholog); FOUND IN autolysosome (ortholog); autophagosome membrane (ortholog); chaperone-mediated autophagy translocation complex (ortholog) | NW_004955572 | 1423048 | 1464443 | Chinchilla | 93 | description | gene, protein-coding, MODEL [RefSeq] |
| 8996615 | Lars1 | leucyl-tRNA synthetase 1 | ENCODES a protein that exhibits aminoacyl-tRNA deacylase activity (ortholog); glutamine-tRNA ligase activity (ortholog); GTPase activator activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to amino acid stim ulus (ortholog); cellular response to L-leucine (ortholog); ASSOCIATED WITH infantile liver failure syndrome 1 (ortholog); microcephaly (ortholog); sensorineural hearing loss (ortholog); FOUND IN aminoacyl-tRNA synthetase multienzyme complex (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955415 | 7923292 | 7983757 | Chinchilla | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 9006410 | Map1lc3c | microtubule associated protein 1 light chain 3 gamma | ENCODES a protein that exhibits phosphatidylethanolamine binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN aggrephagy (ortholog); autophagosome maturation (ortholog); cellular response to starvation (ortholog); PARTICIPATES IN autophag y pathway; FOUND IN autophagosome (ortholog); cytoplasmic ribonucleoprotein granule (ortholog) | NW_004955406 | 5769894 | 5774806 | Chinchilla | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 8895901 | Map3k5 | mitogen-activated protein kinase kinase kinase 5 | ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); JUN kinase kinase kinase activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); cellular response to amino acid starvation (ortholog); cellular respon se to hydrogen peroxide (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Arterial Injury (ortholog); Brain Hypoxia-Ischemia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); external side of plasma membrane (ortholog) | NW_004955439 | 162499 | 376919 | Chinchilla | 131 | description | gene, protein-coding, MODEL [RefSeq] |
| 8748803 | Mapk8 | mitogen-activated protein kinase 8 | ENCODES a protein that exhibits enzyme binding (ortholog); histone deacetylase binding (ortholog); histone deacetylase regulator activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to amyloid-beta (ortholog); cellular response to hydrogen peroxide (ortholog); PARTICIPATES IN adenosine signaling pathway; c-Jun N-terminal kinases MAPK signaling pathway; ceramide signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Acute Liver Failure (ortholog); Acute Otitis Media (ortholog); FOUND IN axon (ortholog); basal dendrite (ortholog); cytoplasm (ortholog) | NW_004955556 | 1593552 | 1705543 | Chinchilla | 232 | description | gene, protein-coding, MODEL [RefSeq] |
| 8883317 | Max | MYC associated transcriptional regulator X | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to peptide hormone stimulus (ortholog); cellular response to star -weight:700;'>starvation (ortholog); negative regulation of gene expression (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); Hereditary Paraganglioma-Pheochromocytoma Syndromes (ortholog); lung small cell carcinoma (ortholog); FOUND IN chromatin (ortholog); dendrite (ortholog); Mad-Max complex (ortholog) | NW_004955466 | 4816568 | 4842659 | Chinchilla | 79 | description | gene, protein-coding, MODEL [RefSeq] |
| 8882542 | Mfsd2a | MFSD2 lysolipid transporter A, lysophospholipid | ENCODES a protein that exhibits fatty acid transmembrane transporter activity (ortholog); long-chain fatty acid transmembrane transporter activity (ortholog); lysophosphatidylcholine flippase activity (ortholog); INVOLVED IN brain development (ortholog); cellular response to star :700;'>starvation (ortholog); cognition (ortholog); ASSOCIATED WITH cryptorchidism (ortholog); genetic disease (ortholog); hepatocellular carcinoma (ortholog); FOUND IN lysosome (ortholog); plasma membrane (ortholog) | NW_004955452 | 17430850 | 17443830 | Chinchilla | 58 | description | gene, protein-coding, MODEL [RefSeq] |
| 9005142 | Mios | meiosis regulator for oocyte development | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); central nervous system myelin formation (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (ortholog); GATOR2 complex (ortholog) ; lysosomal membrane (ortholog) | NW_004955432 | 14658624 | 14693116 | Chinchilla | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 8879551 | Mybbp1a | MYB binding protein 1a | ENCODES a protein that exhibits E-box binding (ortholog); sequence-specific DNA binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); circadian regulation of gene expression (ortholog); intrinsic apoptotic signaling pathway by p53 class mediator (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Meniere's disease (ortholog); Prostatic Neoplasms (ortholog); FOUND IN B-WICH complex (ortholog); cytoplasm (ortholog); NLS-dependent protein nuclear import complex (ortholog) | NW_004955467 | 12390371 | 12405055 | Chinchilla | 30 | description | gene, protein-coding, MODEL [RefSeq] |
| 9034366 | Myh13 | myosin heavy chain 13 | INVOLVED IN cellular response to starvation (ortholog); ASSOCIATED WITH osteoarthritis (ortholog); FOUND IN myofibril (ortholog) | NW_004955467 | 6816393 | 6872754 | Chinchilla | 3 | description | gene, protein-coding, MODEL [RefSeq] |
| 8742041 | Nprl2 | NPR2 like, GATOR1 complex subunit | ENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of kinase activity (ortholog); negative regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR si gnaling pathway; ASSOCIATED WITH epilepsy (ortholog); familial focal epilepsy with variable foci (ortholog); familial focal epilepsy with variable foci 1 (ortholog); FOUND IN GATOR1 complex (ortholog); lysosomal membrane (ortholog) | NW_004955532 | 2148950 | 2152671 | Chinchilla | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 8972231 | Nprl3 | NPR3 like, GATOR1 complex subunit | INVOLVED IN aorta morphogenesis (ortholog); cardiac muscle tissue development (ortholog); cellular response to amino acid starvation (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH epilepsy (ortholog); familial focal epilepsy with variable fo ci 1 (ortholog); familial focal epilepsy with variable foci 3 (ortholog); FOUND IN GATOR1 complex (ortholog); lysosomal membrane (ortholog) | NW_004955442 | 17025232 | 17068399 | Chinchilla | 22 | description | gene, protein-coding, MODEL [RefSeq] |
| 8952085 | Nuak2 | NUAK family kinase 2 | ENCODES a protein that exhibits ATP binding (ortholog); magnesium ion binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); cellular response to glucose starvation (ortholog); negative re gulation of apoptotic process (ortholog); ASSOCIATED WITH Anencephaly 2 (ortholog); FOUND IN nuclear speck (ortholog) | NW_004955406 | 41050396 | 41069066 | Chinchilla | 22 | description | gene, protein-coding, MODEL [RefSeq] |
| 8845463 | Nupr2 | nuclear protein 2, transcriptional regulator | INVOLVED IN cellular response to starvation (ortholog); DNA damage response (ortholog); negative regulation of cell population proliferation (ortholog); FOUND IN nucleus (ortholog) | NW_004955456 | 8268429 | 8269517 | Chinchilla | 6 | description | gene, protein-coding, MODEL [RefSeq] |
| 8890917 | Oaz3 | ornithine decarboxylase antizyme 3 | The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cel ls. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis pathway; thus, completing the auto-regulatory circuit. This gene encodes antizyme 3, the third member of the antizyme family. Like antizymes 1 and 2, antizyme 3 inhibits ODC activity and polyamine uptake, however, it does not stimulate ODC degradation. Also, while antizymes 1 and 2 have broad tissue distribution, expression of antizyme 3 is restricted to haploid germ cells in testis, suggesting a distinct role for this antizyme in spermiogenesis. Antizyme 3 gene knockout studies in mice showed that homozygous mutant male mice were infertile, and indicated the likely role of this antizyme in the formation of a rigid connection between the sperm head and tail during spermatogenesis. This transcript initiates translation from a non-AUG (CUG) start codon that is highly conserved amongst the antizyme 3 orthologs. [provided by RefSeq, Aug 2014] | NW_004955589 | 654088 | 658003 | Chinchilla | 23 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 8887471 | Pcsk9 | proprotein convertase subtilisin/kexin type 9 | ENCODES a protein that exhibits apolipoprotein binding (ortholog); apolipoprotein receptor binding (ortholog); endopeptidase activity (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); cellular response to starvation (ortholog); cholestero l homeostasis (ortholog); ASSOCIATED WITH autosomal recessive hypercholesterolemia (ortholog); coronary artery disease (ortholog); Coronary Disease (ortholog); FOUND IN cell surface (ortholog); COPII-coated ER to Golgi transport vesicle (ortholog); cytoplasm (ortholog) | NW_004955464 | 4424583 | 4439805 | Chinchilla | 104 | description | gene, protein-coding, MODEL [RefSeq] |
| 8785185 | Pdk4 | pyruvate dehydrogenase kinase 4 | ENCODES a protein that exhibits ATP binding (ortholog); protein kinase activity (ortholog); pyruvate dehydrogenase (acetyl-transferring) kinase activity (ortholog); INVOLVED IN cellular response to fatty acid (ortholog); cellular response to starvation (ortholog ); glucose homeostasis (ortholog); PARTICIPATES IN pyruvate metabolic pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Experimental Diabetes Mellitus (ortholog); hepatocellular carcinoma (ortholog); FOUND IN mitochondrion (ortholog) | NW_004955432 | 12169548 | 12182064 | Chinchilla | 30 | description | gene, protein-coding, MODEL [RefSeq] |
| 9026612 | Pdp2 | pyruvate dehyrogenase phosphatase catalytic subunit 2 | ENCODES a protein that exhibits [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity (ortholog); protein serine/threonine phosphatase activity (ortholog); INVOLVED IN peptidyl-threonine dephosphorylation (ortholog); response to starvation (ortholo g); T-helper cell differentiation (ortholog); PARTICIPATES IN pyruvate metabolic pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); prostate cancer (ortholog); FOUND IN mitochondrion (ortholog) | NW_004955433 | 23392193 | 23396229 | Chinchilla | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 9001641 | Pick1 | protein interacting with PRKCA 1 | ENCODES a protein that exhibits actin filament binding (ortholog); Arp2/3 complex binding (ortholog); cytoskeletal protein binding (ortholog); INVOLVED IN AMPA glutamate receptor clustering (ortholog); cellular response to decreased oxygen levels (ortholog); cellular response to glucose star 'font-weight:700;'>starvation (ortholog); PARTICIPATES IN protein kinase C (PKC) signaling pathway; ASSOCIATED WITH amphetamine abuse (ortholog); substance-induced psychosis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); dendrite (ortholog) | NW_004955413 | 24383130 | 24399092 | Chinchilla | 123 | description | gene, protein-coding, MODEL [RefSeq] |
| 9043035 | Pik3c2a | phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha | ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity (ortholog); 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity (ortholog); 1-phosphatidylinositol-4-phosphate 3-kinase activity (ortholog); INVOLVED IN autophagosome organization (ortholog); cellular response to star yle='font-weight:700;'>starvation (ortholog); endocytosis (ortholog); PARTICIPATES IN phosphoinositide metabolic pathway; ASSOCIATED WITH Dwarfism (ortholog); Oculoskeletodental Syndrome (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN clathrin-coated vesicle (ortholog); cytoplasm (ortholog); nucleoplasm (ortholog) | NW_004955414 | 31896161 | 31999730 | Chinchilla | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 8941135 | Pik3c2b | phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta | ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity (ortholog); 1-phosphatidylinositol-4-phosphate 3-kinase activity (ortholog); lipid kinase activity (ortholog); INVOLVED IN autophagosome organization (ortholog); cellular response to starva tion (ortholog); macroautophagy (ortholog); ASSOCIATED WITH Neoplasm Metastasis (ortholog); FOUND IN cytosol (ortholog); endocytic vesicle (ortholog); plasma membrane (ortholog) | NW_004955406 | 40247690 | 40317556 | Chinchilla | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 8828809 | Pik3r4 | phosphoinositide-3-kinase regulatory subunit 4 | INVOLVED IN autophagosome maturation (ortholog); cellular response to glucose starvation (ortholog); early endosome to late endosome transport (ortholog); PARTICIPATES IN autophagy pathway; inositol metabolic pathway; phosphoinositide metabolic pathway; FOUND IN axoneme (ortholog); late endosome (ortholog); phosphatidylinositol 3-kinase complex, class III (ortholog) | NW_004955501 | 7604934 | 7681947 | Chinchilla | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 8911469 | Plin2 | perilipin 2 | INVOLVED IN cellular response to glucose starvation (ortholog); lipid droplet disassembly (ortholog); lipid storage (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Hypertriglyceridemia (ortho log); Insulin Resistance (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); lipid droplet (ortholog) | NW_004955434 | 21573860 | 21580990 | Chinchilla | 26 | description | gene, protein-coding, MODEL [RefSeq] |
| 8786859 | Plin3 | perilipin 3 | INVOLVED IN cellular response to glucose starvation (ortholog); lipid droplet disassembly (ortholog); lipid storage (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN lipid droplet (ortholog) | NW_004955495 | 4177701 | 4190052 | Chinchilla | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 8785792 | Pmaip1 | phorbol-12-myristate-13-acetate-induced protein 1 | INVOLVED IN apoptotic process (ortholog); cellular response to glucose starvation (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN intrinsic apoptotic pathway; ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); COVID-19 (ortholog ); substance-related disorder (ortholog); FOUND IN Bcl-2 family protein complex (ortholog); cytosol (ortholog); mitochondrion (ortholog) | NW_004955402 | 44005517 | 44010722 | Chinchilla | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 8768302 | Ppara | peroxisome proliferator activated receptor alpha | ENCODES a protein that exhibits DNA-binding transcription activator activity (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN behavioral response to nicotine (ortholog); cellular respons e to fructose stimulus (ortholog); cellular response to starvation (ortholog); ASSOCIATED WITH abdominal obesity-metabolic syndrome (ortholog); acute kidney tubular necrosis (ortholog); alcohol use disorder (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog) | NW_004955413 | 30306563 | 30366245 | Chinchilla | 201 | description | gene, protein-coding, MODEL [RefSeq] |
| 8945095 | Ppm1d | protein phosphatase, Mg2+/Mn2+ dependent 1D | ENCODES a protein that exhibits mitogen-activated protein kinase binding (ortholog); protein serine/threonine phosphatase activity (ortholog); INVOLVED IN cellular response to starvation (ortholog); DNA damage response, signal transduction by p53 class mediator (ortholog); DNA methylation-dependent constitutive heterochromatin formation (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; p38 MAPK signaling pathway; p53 signaling pathway; ASSOCIATED WITH Brain Stem Neoplasms (ortholog); breast cancer (ortholog); Breast Cancer, Familial (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | NW_004955451 | 1878110 | 1915794 | Chinchilla | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 9004368 | Ppp1r15a | protein phosphatase 1 regulatory subunit 15A | ENCODES a protein that exhibits eukaryotic initiation factor eIF2 binding (ortholog); molecular adaptor activity (ortholog); protein kinase binding (ortholog); INVOLVED IN cellular response to antibiotic (ortholog); cellular response to calcium ion starvation (o rtholog); cellular response to carbohydrate stimulus (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Acute-On-Chronic Liver Failure (ortholog); Amaurosis Fugax (ortholog); amyotrophic lateral sclerosis (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); Golgi apparatus (ortholog) | NW_004955559 | 1750227 | 1753607 | Chinchilla | 76 | description | gene, protein-coding, MODEL [RefSeq] |
| 8929315 | Ppp1r3f | protein phosphatase 1 regulatory subunit 3F | ENCODES a protein that exhibits glycogen binding (ortholog); protein phosphatase binding (ortholog); INVOLVED IN regulation of glycogen (starch) synthase activity (ortholog); regulation of glycogen biosynthetic process (ortholog); FOUND IN membrane (ortholog) | NW_004955543 | 750094 | 767894 | Chinchilla | 5 | description | gene, protein-coding, MODEL [RefSeq] |
| 8922679 | Ppp1r3g | protein phosphatase 1 regulatory subunit 3G | ENCODES a protein that exhibits glycogen binding (ortholog); protein phosphatase binding (ortholog); INVOLVED IN glucose homeostasis (ortholog); positive regulation of glycogen (starch) synthase activity (ortholog); positive regulation of glycogen biosynthetic p rocess (ortholog); FOUND IN cytoplasm (ortholog); protein phosphatase type 1 complex (ortholog) | NW_004955465 | 8485273 | 8488181 | Chinchilla | 9 | description | gene, protein-coding, MODEL [RefSeq] |
| 8702555 | Prkaa2 | protein kinase AMP-activated catalytic subunit alpha 2 | ENCODES a protein that exhibits AMP-activated protein kinase activity (ortholog); ATP binding (ortholog); chromatin binding (ortholog); INVOLVED IN cellular response to calcium ion (ortholog); cellular response to glucose starvation (ortholog); cellular response to glucose stimulus (ortholog); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH Cardiac Fibrosis (ortholog); Cardiomegaly (ortholog); cardiomyopathy (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog); cytoplasm (ortholog) | NW_004955464 | 2996608 | 3062197 | Chinchilla | 126 | description | gene, protein-coding, MODEL [RefSeq] |
| 8791147 | Prkch | protein kinase C eta | ENCODES a protein that exhibits diacylglycerol-dependent, calcium-independent serine/threonine kinase activity (ortholog); enzyme binding (ortholog); protein kinase activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of glial cell apoptotic process (ortholog); negative regulation of translation (ortholog); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; protein kinase C (PKC) signaling pathway; ASSOCIATED WITH cerebral infarction (ortholog); obesity (ortholog); substance-related disorder (ortholog); FOUND IN cell-cell junction (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955466 | 8178323 | 8393446 | Chinchilla | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 9016154 | Prkd1 | protein kinase D1 | ENCODES a protein that exhibits diacylglycerol-dependent serine/threonine kinase activity (ortholog); heat shock protein binding (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular respons e to angiotensin (ortholog); cellular response to endothelin (ortholog); PARTICIPATES IN insulin-like growth factor signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Cardiac Fibrosis (ortholog); Cardiomegaly (ortholog); FOUND IN autophagosome membrane (ortholog); cell cortex (ortholog); cell-cell junction (ortholog) | NW_004955409 | 30554095 | 30860588 | Chinchilla | 110 | description | gene, protein-coding, MODEL [RefSeq] |
| 8869129 | Pwwp2a | PWWP domain containing 2A | ENCODES a protein that exhibits chromatin binding (ortholog); histone binding (ortholog); histone H3K36me3 reader activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); positive regulation of transcription elongation by RNA polymerase II (ortholog); regulation of transcriptional star le='font-weight:700;'>start site selection at RNA polymerase II promoter (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog) | NW_004955408 | 14007982 | 14051149 | Chinchilla | 16 | description | gene, protein-coding, MODEL [RefSeq] |
| 8736095 | Ripor1 | RHO family interacting cell polarization regulator 1 | ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); INVOLVED IN cellular response to chemokine (ortholog); cellular response to starvation (ortholog); establishment of Golgi localization (ortholog); FOUND IN cell leading edge (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955484 | 9110208 | 9119678 | Chinchilla | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 8990206 | Rnf152 | ring finger protein 152 | ENCODES a protein that exhibits small GTPase binding (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of TORC1 sign aling (ortholog); positive regulation of autophagy (ortholog); FOUND IN lysosomal membrane (ortholog); lysosome (ortholog); organelle membrane (ortholog) | NW_004955402 | 45774565 | 45846649 | Chinchilla | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 8935375 | Rnf167 | ring finger protein 167 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN cellular response to leucine starvation (ortholog); lysosome localization (ortholog); negative regulation of cell cycle ( ortholog); ASSOCIATED WITH systemic primary carnitine deficiency disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endolysosome membrane (ortholog) | NW_004955467 | 10352650 | 10357214 | Chinchilla | 22 | description | gene, protein-coding, MODEL [RefSeq] |
| 8813800 | Rps25 | ribosomal protein S25 | ENCODES a protein that exhibits structural constituent of ribosome (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); ribosomal small subunit assembly (ortholog); ribosomal small subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; FOUND IN cytosol (ortholog); cytosolic ribosome (ortholog); cytosolic small ribosomal subunit (ortholog) | NW_004955412 | 20126769 | 20129071 | Chinchilla | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 8822187 | Rraga | Ras related GTP binding A | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); phosphoprotein binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to amino acid stimulus (ortholog); cellular response to nu trient levels (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN cytoplasm (ortholog); FNIP-folliculin RagC/D GAP (ortholog); GATOR1 complex (ortholog) | NW_004955434 | 21509528 | 21510885 | Chinchilla | 50 | description | gene, protein-coding, MODEL [RefSeq] |
| 9037806 | Rragc | Ras related GTP binding C | ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); GDP binding (ortholog); GTP binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); positive regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH follicular lymphoma (ortholog); genetic disease (ortholog); LONG-OLSEN-DISTELMAIER SYNDROME (ortholog); FOUND IN cytoplasm (ortholog); FNIP-folliculin RagC/D GAP (ortholog); Gtr1-Gtr2 GTPase complex (ortholog) | NW_004955452 | 16469426 | 16486336 | Chinchilla | 47 | description | gene, protein-coding, MODEL [RefSeq] |
| 8883673 | Rragd | Ras related GTP binding D | ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); GTPase activity (ortholog); INVOLVED IN cellular response to L-leucine (ortholog); cellular response to leucine starvation (ortholog); positive regulation of TORC1 signaling (ortholo g); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH genetic disease (ortholog); renal hypomagnesemia 7, with or without dilated cardiomyopathy (ortholog); FOUND IN cytoplasm (ortholog); Gtr1-Gtr2 GTPase complex (ortholog); lysosome (ortholog) | NW_004955411 | 16111931 | 16155662 | Chinchilla | 31 | description | gene, protein-coding, MODEL [RefSeq] |
| 9016401 | Rrp8 | ribosomal RNA processing 8 | INVOLVED IN cellular response to glucose starvation (ortholog); energy homeostasis (ortholog); intrinsic apoptotic signaling pathway by p53 class mediator (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN chromatin silencing complex (orth olog); cytosol (ortholog); eNoSc complex (ortholog) | NW_004955414 | 22311038 | 22316144 | Chinchilla | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 8890675 | Sar1a | secretion associated Ras related GTPase 1A | ENCODES a protein that exhibits amino acid sensor activity (ortholog); G protein activity (ortholog); INVOLVED IN cellular response to leucine starvation (ortholog); COPII vesicle coating (ortholog); COPII-coated vesicle cargo loading (ortholog); FOUND IN COPII vesicle coat (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum exit site (ortholog) | NW_004955437 | 21075632 | 21093608 | Chinchilla | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 9007293 | Sar1b | secretion associated Ras related GTPase 1B | ENCODES a protein that exhibits amino acid sensor activity (ortholog); G protein activity (ortholog); INVOLVED IN cellular response to leucine starvation (ortholog); COPII vesicle coating (ortholog); COPII-coated vesicle cargo loading (ortholog); ASSOCIATED WITH chylomicron retention disease (ortholog); genetic disease (ortholog); Hereditary Pancreatitis (ortholog); FOUND IN COPII vesicle coat (ortholog); cytosol (ortholog); endoplasmic reticulum exit site (ortholog) | NW_004955408 | 5737197 | 5761228 | Chinchilla | 26 | description | gene, protein-coding, MODEL [RefSeq] |
| 8987617 | Seh1l | SEH1 like nucleoporin | INVOLVED IN attachment of mitotic spindle microtubules to kinetochore (ortholog); cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); PARTICIPATES IN mRNA nuclear export pathway; ASSOCIATED WITH tooth agenesis (ortholog); FOUND IN GATOR2 complex (ortholog); kinetochore (ortholog); lysosomal membrane (ortholog) | NW_004955402 | 679109 | 698624 | Chinchilla | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 9046128 | Sesn1 | sestrin 1 | ENCODES a protein that exhibits L-leucine binding (ortholog); INVOLVED IN cellular oxidant detoxification (ortholog); cellular response to amino acid starvation (ortholog); cellular response to amino acid stimulus (ortholog); FOUND IN cytoplasm (ortholog); fibri llar center (ortholog); GATOR2 complex (ortholog) | NW_004955411 | 34033986 | 34051171 | Chinchilla | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 8849954 | Sesn2 | sestrin 2 | ENCODES a protein that exhibits GDP-dissociation inhibitor activity (ortholog); L-leucine binding (ortholog); peroxidase activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cellular oxidant detoxification (ortholog); cellular response to amino acid star ight:700;'>starvation (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); Hepatomegaly (ortholog); FOUND IN Atg1/ULK1 kinase complex (ortholog); cytoplasm (ortholog); GATOR2 complex (ortholog) | NW_004955452 | 7392644 | 7417204 | Chinchilla | 78 | description | gene, protein-coding, MODEL [RefSeq] |
| 8898445 | Sh3glb1 | SH3 domain containing GRB2 like, endophilin B1 | ENCODES a protein that exhibits fatty acid binding (ortholog); lysophosphatidic acid acyltransferase activity (ortholog); phosphatidylinositol 3-kinase activator activity (ortholog); INVOLVED IN 'de novo' post-translational protein folding (ortholog); autophagic cell death (ortholog); cellular respo nse to amino acid starvation (ortholog); PARTICIPATES IN mitochondria fission pathway; FOUND IN autophagosome membrane (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955423 | 7393186 | 7414199 | Chinchilla | 51 | description | gene, protein-coding, MODEL [RefSeq] |
| 8766123 | Sirt1 | sirtuin 1 | ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); caspase binding (ortholog); deacetylase activity (ortholog); INVOLVED IN angiogenesis (ortholog); behavioral response to starvation (ortholog); cardiac muscle cell apoptotic process (o rtholog); PARTICIPATES IN histone modification pathway; hypoxia inducible factor pathway; p53 signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); FOUND IN axon (ortholog); chromatin (ortholog); chromatin silencing complex (ortholog) | NW_004955425 | 20280725 | 20307663 | Chinchilla | 451 | description | gene, protein-coding, MODEL [RefSeq] |
| 8719421 | Slc2a1 | solute carrier family 2 member 1 | ENCODES a protein that exhibits D-glucose transmembrane transporter activity (ortholog); dehydroascorbic acid transmembrane transporter activity (ortholog); fucose transmembrane transporter activity (ortholog); INVOLVED IN cellular hyperosmotic response (ortholog); cellular response to glucose star style='font-weight:700;'>starvation (ortholog); cellular response to mechanical stimulus (ortholog); PARTICIPATES IN facilitative sugar transporter mediated glucose transport pathway; Glut1 deficiency syndrome pathway; hypoxia inducible factor pathway; ASSOCIATED WITH alcohol dependence (ortholog); Alcohol-Related Disorders (ortholog); Alzheimer's disease (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); caveola (ortholog) | NW_004955537 | 2408042 | 2438788 | Chinchilla | 168 | description | gene, protein-coding, MODEL [RefSeq] |
| 8828615 | Slc38a3 | solute carrier family 38 member 3 | ENCODES a protein that exhibits L-alanine transmembrane transporter activity (ortholog); L-asparagine transmembrane transporter activity (ortholog); L-asparagine, sodium:proton antiporter activity (ortholog); INVOLVED IN asparagine transmembrane transport (ortholog); asparagine transport (ortholog); cellular response to potassium ion starvation (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 102 (ortholog); Dwarfism (ortholog); Endotoxemia (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); membrane (ortholog) | NW_004955532 | 2023694 | 2046556 | Chinchilla | 81 | description | gene, protein-coding, MODEL [RefSeq] |
| 8795371 | Slc39a4 | solute carrier family 39 member 4 | ENCODES a protein that exhibits identical protein binding (ortholog); metal ion binding (ortholog); zinc ion binding (ortholog); INVOLVED IN cellular response to zinc ion starvation (ortholog); intracellular zinc ion homeostasis (ortholog); zinc ion transmembran e transport (ortholog); ASSOCIATED WITH acrodermatitis (ortholog); acrodermatitis enteropathica (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); cytoplasmic vesicle (ortholog); endosome (ortholog) | NW_004955454 | 3041316 | 3047419 | Chinchilla | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 8995536 | Slc39a5 | solute carrier family 39 member 5 | ENCODES a protein that exhibits zinc ion transmembrane transporter activity (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cellular response to zinc ion starvation (ortholog); eye development (ortholog); ASSOCIATED WITH Myopia 24, Autosomal Dominant ( ortholog); retinitis pigmentosa 1 (ortholog); FOUND IN basolateral plasma membrane (ortholog) | NW_004955458 | 3843492 | 3849794 | Chinchilla | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 8849262 | Slc3a2 | solute carrier family 3 member 2 | ENCODES a protein that exhibits aromatic amino acid transmembrane transporter activity (ortholog); double-stranded RNA binding (ortholog); exogenous protein binding (ortholog); INVOLVED IN amino acid import across plasma membrane (ortholog); cellular response to glucose star '>starvation (ortholog); isoleucine transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); Liver Metastasis (ortholog); FOUND IN amino acid transport complex (ortholog); apical plasma membrane (ortholog); apical pole of neuron (ortholog) | NW_004955599 | 376133 | 391434 | Chinchilla | 101 | description | gene, protein-coding, MODEL [RefSeq] |
| 8899261 | Slc61a1 | solute carrier family 61 member 1 | ENCODES a protein that exhibits molybdate ion transmembrane transporter activity (ortholog); INVOLVED IN molybdate ion transport (ortholog); response to food (ortholog); response to starvation (ortholog) | NW_004955458 | 519566 | 521778 | Chinchilla | 9 | description | gene, protein-coding, MODEL [RefSeq] |
| 8913105 | Slco2b1 | solute carrier organic anion transporter family member 2B1 | ENCODES a protein that exhibits prostaglandin transmembrane transporter activity (ortholog); secondary active transmembrane transporter activity (ortholog); transmembrane transporter activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to iron ion star 'font-weight:700;'>starvation (ortholog); heme import into cell (ortholog); PARTICIPATES IN statin pharmacokinetics pathway; ASSOCIATED WITH liver cancer (ortholog); pancreatic cancer (ortholog); FOUND IN apical plasma membrane (ortholog); basal plasma membrane (ortholog); plasma membrane (ortholog) | NW_004955414 | 16615012 | 16664784 | Chinchilla | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 8882643 | Smdt1 | single-pass membrane protein with aspartate rich tail 1 | ENCODES a protein that exhibits channel activator activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN calcium import into the mitochondrion (ortholog); cellular response to calcium ion starvation (ortholog); mitochondrial calcium ion homeostasis (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); uniplex complex (ortholog) | NW_004955413 | 27480938 | 27485729 | Chinchilla | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 8792571 | Sp7 | Sp7 transcription factor | ENCODES a protein that exhibits DEAD/H-box RNA helicase binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to parathyroid hormone stimulus (ortholog); cellular response to zinc ion star ='font-weight:700;'>starvation (ortholog); cementum mineralization (ortholog); ASSOCIATED WITH aortic valve stenosis (ortholog); BCARD syndrome (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | NW_004955458 | 583981 | 602856 | Chinchilla | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 9062386 | Srebf1 | sterol regulatory element binding transcription factor 1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to fatty acid (ortholog); cellular response to insulin stimulus (ortholog); cellular response to ... (more)pan style='font-weight:700;'>starvation (ortholog); PARTICIPATES IN mTOR signaling pathway; sterol regulatory element-binding protein signaling pathway; triacylglycerol metabolic pathway; ASSOCIATED WITH alcoholic hepatitis (ortholog); atherosclerosis (ortholog); coronary artery disease (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); membrane (ortholog) | NW_004955577 | 171425 | 183669 | Chinchilla | 161 | description | gene, protein-coding, MODEL [RefSeq] |
| 9061920 | Srebf2 | sterol regulatory element binding transcription factor 2 | ENCODES a protein that exhibits C-8 sterol isomerase activity (ortholog); chromatin binding (ortholog); DNA binding (ortholog); INVOLVED IN cellular response to low-density lipoprotein particle stimulus (ortholog); cellular response to starvation (ortholog); cho lesterol homeostasis (ortholog); PARTICIPATES IN altered p53 signaling pathway; sterol regulatory element-binding protein signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); atherosclerosis (ortholog); Breast Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); dendrite (ortholog); endoplasmic reticulum (ortholog) | NW_004955413 | 27271717 | 27326655 | Chinchilla | 94 | description | gene, protein-coding, MODEL [RefSeq] |
| 8970913 | Stk24 | serine/threonine kinase 24 | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); cellular response to starvation (ortholog); execution phase of apoptosis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); FAR/SIN/STRIPAK complex (ortholog) | NW_004955404 | 11943308 | 12049688 | Chinchilla | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 8715851 | Stk26 | serine/threonine kinase 26 | ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); magnesium ion binding (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); cellular response to starvation (ortholog); intracellular signal transdu ction (ortholog); FOUND IN apical plasma membrane (ortholog); cell periphery (ortholog); cytoplasm (ortholog) | NW_004955473 | 2819644 | 2878561 | Chinchilla | 33 | description | gene, protein-coding, MODEL [RefSeq] |
| 8991222 | Suv39h1 | SUV39H1 histone lysine methyltransferase | ENCODES a protein that exhibits histone H3K14ub reader activity (ortholog); histone H3K9 methyltransferase activity (ortholog); histone H3K9 trimethyltransferase activity (ortholog); INVOLVED IN blastocyst hatching (ortholog); cellular response to glucose starva tion (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN histone modification pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH Chromosome Breakage (ortholog); Ependymomas (ortholog); Neoplastic Cell Transformation (ortholog); FOUND IN chromatin (ortholog); chromatin silencing complex (ortholog); eNoSc complex (ortholog) | NW_004955543 | 258479 | 271128 | Chinchilla | 76 | description | gene, protein-coding, MODEL [RefSeq] |
| 8974028 | Tbc1d7 | TBC1 domain family member 7 | ENCODES a protein that exhibits GTPase activator activity (ortholog); small GTPase binding (ortholog); INVOLVED IN activation of GTPase activity (ortholog); cellular response to starvation (ortholog); negative regulation of cilium assembly (ortholog); PARTICIPAT ES IN mTOR signaling pathway; FOUND IN ciliary basal body (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog) | NW_004955465 | 1362453 | 1380814 | Chinchilla | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 8702839 | Tbl2 | transducin beta like 2 | ENCODES a protein that exhibits phosphoprotein binding (ortholog); protein kinase binding (ortholog); translation initiation factor binding (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to hypoxia (ortholog); endop lasmic reticulum unfolded protein response (ortholog); ASSOCIATED WITH COVID-19 (ortholog); microcephaly (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytosol (ortholog); endoplasmic reticulum (ortholog) | NW_004955456 | 14128847 | 14134314 | Chinchilla | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 8887943 | Tnfrsf11a | TNF receptor superfamily member 11a | ENCODES a protein that exhibits cytokine binding (ortholog); transmembrane signaling receptor activity (ortholog); tumor necrosis factor receptor activity (ortholog); INVOLVED IN adaptive immune response (ortholog); cellular response to zinc ion starvation (orth olog); circadian temperature homeostasis (ortholog); ASSOCIATED WITH Alveolar Bone Loss (ortholog); autosomal recessive osteopetrosis 7 (ortholog); B-Cell Chronic Lymphocytic Leukemia (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); membrane raft (ortholog) | NW_004955402 | 46242329 | 46298157 | Chinchilla | 58 | description | gene, protein-coding, MODEL [RefSeq] |
| 8890981 | Tnrc6a | trinucleotide repeat containing adaptor 6A | INVOLVED IN cellular response to starvation (ortholog); endoderm development (ortholog); miRNA-mediated gene silencing by inhibition of translation (ortholog); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH familial adult myoclonic epilepsy 6 (ortholog); Myoc lonic Epilepsies (ortholog); FOUND IN P-body (ortholog); RISC complex (ortholog) | NW_004955493 | 3057035 | 3243668 | Chinchilla | 27 | description | gene, protein-coding, MODEL [RefSeq] |
| 8915054 | Ttc5 | tetratricopeptide repeat domain 5 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); ribosome binding (ortholog); INVOLVED IN cellular response to starvation (ortholog); DNA damage response (ortholog); positive regulation of mRNA catabolic process (ortholog); P ARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH CEREBRAL ATROPHY AND VARIABLE FACIAL DYSMORPHISM (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog) | NW_004955550 | 1073697 | 1105055 | Chinchilla | 27 | description | gene, protein-coding, MODEL [RefSeq] |
| 8927345 | Ucp2 | uncoupling protein 2 | ENCODES a protein that exhibits antiporter activity (ortholog); chloride transmembrane transporter activity (ortholog); GDP binding (ortholog); INVOLVED IN C4-dicarboxylate transport (ortholog); cellular response to amino acid starvation (ortholog); cellular res ponse to glucose stimulus (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH Acute Liver Failure (ortholog); Animal Mammary Neoplasms (ortholog); Brain Injuries (ortholog); FOUND IN mitochondrial membrane (ortholog); mitochondrion (ortholog) | NW_004955414 | 17592914 | 17596477 | Chinchilla | 98 | description | gene, protein-coding, MODEL [RefSeq] |
| 8764869 | Upp1 | uridine phosphorylase 1 | ENCODES a protein that exhibits deoxyuridine phosphorylase activity (ortholog); identical protein binding (ortholog); thymidine phosphorylase activity (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); CMP catabolic process (ortholog); d CMP catabolic process (ortholog); ASSOCIATED WITH allergic contact dermatitis (ortholog); long QT syndrome (ortholog); middle cerebral artery infarction (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog) | NW_004955456 | 5365912 | 5385336 | Chinchilla | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 8742304 | Vldlr | very low density lipoprotein receptor | ENCODES a protein that exhibits apolipoprotein binding (ortholog); calcium-dependent protein binding (ortholog); cargo receptor activity (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to hypoxia (ortholog); cellular response to insulin stimulus (ortholog); PARTICIPATES IN altered Reelin signaling pathway; Reelin signaling pathway; ASSOCIATED WITH age related macular degeneration 1 (ortholog); Alzheimer's disease (ortholog); amenorrhea (ortholog); FOUND IN apical part of cell (ortholog); cell surface (ortholog); extracellular space (ortholog) | NW_004955434 | 7013092 | 7050103 | Chinchilla | 78 | description | gene, protein-coding, MODEL [RefSeq] |
| 8790057 | Wdr24 | WD repeat domain 24 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); positive regulation of protein kinase activity (ortholog); PARTICIPA TES IN mTOR signaling pathway; FOUND IN GATOR2 complex (ortholog); lysosomal membrane (ortholog) | NW_004955442 | 16513074 | 16519296 | Chinchilla | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 8785612 | Wdr45 | WD repeat domain 45 | ENCODES a protein that exhibits phosphatidylinositol phosphate binding (ortholog); phosphatidylinositol-3-phosphate binding (ortholog); protein kinase binding (ortholog); INVOLVED IN autophagosome assembly (ortholog); autophagy (ortholog); cellular response to star an>vation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); CEREBRAL-CEREBELLAR-COLOBOMA SYNDROME, X-LINKED (ortholog); Developmental Disabilities (ortholog); FOUND IN phagophore assembly site (ortholog) | NW_004955543 | 597796 | 604163 | Chinchilla | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 8969247 | Wdr45b | WD repeat domain 45B | ENCODES a protein that exhibits phosphatidylinositol-3,5-bisphosphate binding (ortholog); phosphatidylinositol-3-phosphate binding (ortholog); TSC1-TSC2 complex binding (ortholog); INVOLVED IN autophagosome assembly (ortholog); cellular response to starvation (o rtholog); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorder with Spastic Quadriplegia and Brain Abnormalities with or without Seizures (ortholog); FOUND IN cytosol (ortholog); lysosome (ortholog); phagophore assembly site (ortholog) | NW_004955506 | 515364 | 556507 | Chinchilla | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 8907958 | Wdr59 | WD repeat domain 59 | INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); positive regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN GATOR2 complex (ortholog); lysosomal membrane (ortholog) | NW_004955484 | 2576505 | 2668001 | Chinchilla | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 8909297 | Wipi1 | WD repeat domain, phosphoinositide interacting 1 | ENCODES a protein that exhibits nuclear androgen receptor binding (ortholog); nuclear estrogen receptor binding (ortholog); phosphatidylinositol-3,5-bisphosphate binding (ortholog); INVOLVED IN autophagosome assembly (ortholog); autophagy (ortholog); cellular response to star ;'>starvation (ortholog); ASSOCIATED WITH cholestasis (ortholog); lipid storage disease (ortholog); FOUND IN autophagosome membrane (ortholog); cytoplasm (ortholog); endosome membrane (ortholog) | NW_004955478 | 4309975 | 4341107 | Chinchilla | 22 | description | gene, protein-coding, MODEL [RefSeq] |
| 8858267 | Wipi2 | WD repeat domain, phosphoinositide interacting 2 | ENCODES a protein that exhibits phosphatidylinositol-3,5-bisphosphate binding (ortholog); phosphatidylinositol-3-phosphate binding (ortholog); phosphatidylinositol-5-phosphate binding (ortholog); INVOLVED IN autophagosome assembly (ortholog); autophagosome maturation (ortholog); cellular response to starvation (ortholog); ASSOCIATED WITH INTELLECTUAL DEVELOPMENTAL DISORDER WITH SHORT STATURE AND VARIABLE SKELETAL ANOMALIES (ortholog); FOUND IN autophagosome (ortholog); autophagosome membrane (ortholog); cytosol (ortholog) | NW_004955460 | 10090343 | 10132724 | Chinchilla | 27 | description | gene, protein-coding, MODEL [RefSeq] |
| 8832082 | Wnt2b | Wnt family member 2B | INVOLVED IN canonical Wnt signaling pathway (ortholog); cellular response to starvation (ortholog); chondrocyte differentiation (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Diarrhea 9 (ortholog); endodermal sinus tumor (ortholog); Failure to Thrive (ortholog) | NW_004955435 | 15948262 | 15962958 | Chinchilla | 23 | description | gene, protein-coding, MODEL [RefSeq] |
| 8962398 | Wrn | WRN RecQ like helicase | ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); 3'-5' exonuclease activity (ortholog); 3'-flap-structured DNA binding (ortholog); INVOLVED IN base-excision repair (ortholog); cellular response to gamma radiation (ortholog); cellular response to star starvation (ortholog); ASSOCIATED WITH breast cancer (ortholog); coronary artery disease (ortholog); diffuse scleroderma (ortholog); FOUND IN centrosome (ortholog); chromosome, telomeric region (ortholog); nuclear speck (ortholog) | NW_004955463 | 7495243 | 7633532 | Chinchilla | 103 | description | gene, protein-coding, MODEL [RefSeq] |
| 8810315 | Yars1 | tyrosyl-tRNA synthetase 1 | ENCODES a protein that exhibits small molecule binding (ortholog); tyrosine-tRNA ligase activity (ortholog); INVOLVED IN response to starvation (ortholog); tyrosyl-tRNA aminoacylation (ortholog); PARTICIPATES IN phenylketonuria pathway; tyrosinemia type II pathw ay; tyrosinemia type III pathway; ASSOCIATED WITH Agenesis of Corpus Callosum (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nuclear body (ortholog) | NW_004955452 | 11046047 | 11078016 | Chinchilla | 26 | description | gene, protein-coding, MODEL [RefSeq] |
| 8701022 | Yme1l1 | YME1 like 1 ATPase | ENCODES a protein that exhibits ATP-dependent peptidase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to starvation (ortholog); mitochondrial protein catabolic process (ortholog); ASSOCIATED WITH 3-methylglutaconic aciduria (ortholog); dilated cardiomyopathy (ortholog); fundus dystrophy (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog) | NW_004955429 | 2550611 | 2572472 | Chinchilla | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 9035209 | Ywhag | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma | ENCODES a protein that exhibits identical protein binding (ortholog); insulin-like growth factor receptor binding (ortholog); phosphorylation-dependent protein binding (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to insulin stimulus (ortholog); negative regulation of TORC1 signaling (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; interleukin-3 signaling pathway; mTOR signaling pathway; ASSOCIATED WITH Constipation (ortholog); COVID-19 (ortholog); Creutzfeldt-Jakob disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial matrix (ortholog) | NW_004955456 | 14939130 | 14970248 | Chinchilla | 116 | description | gene, protein-coding, MODEL [RefSeq] |
| 9016806 | Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); identical protein binding (ortholog); phosphoserine residue binding (ortholog); INVOLVED IN angiogenesis (ortholog); cellular response to glucose starvation (ortholog); ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; histone modification pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; ASSOCIATED WITH absence epilepsy (ortholog); Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); FOUND IN cell leading edge (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955417 | 16047263 | 16070506 | Chinchilla | 182 | description | gene, protein-coding, MODEL [RefSeq] |
| 8965979 | Zc3h12a | zinc finger CCCH-type containing 12A | ENCODES a protein that exhibits chromatin binding (ortholog); cysteine-type deubiquitinase activity (ortholog); DNA binding (ortholog); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); cellular response to chemokine (ortholog); cellular response to glucose star starvation (ortholog); ASSOCIATED WITH Acute Experimental Autoimmune Encephalomyelitis (ortholog); Acute Lung Injury (ortholog); Arterial Occlusive Diseases (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic ribonucleoprotein granule (ortholog); cytoskeleton (ortholog) | NW_004955452 | 15306398 | 15314959 | Chinchilla | 113 | description | gene, protein-coding, MODEL [RefSeq] |
| 8945522 | Zfyve1 | zinc finger FYVE-type containing 1 | ENCODES a protein that exhibits 1-phosphatidylinositol binding (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-3,4-bisphosphate binding (ortholog); INVOLVED IN cellular response to starvation (ortholog); host-mediate d activation of viral genome replication (ortholog); lipid droplet formation (ortholog); FOUND IN autophagosome (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog) | NW_004955523 | 2334175 | 2388612 | Chinchilla | 31 | description | gene, protein-coding, MODEL [RefSeq] |