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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:antithrombotic drug pathway
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Accession:PW:0001651 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent the formation of blood clots. They are further classified depending on the blood clotting processes they affect. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: anticoagulant drug pathway


show annotations for term's descendants           Sort by:
abciximab pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00265 NCBI chr12:18,860,739...18,877,381
Ensembl chr12:18,860,739...18,877,381 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00265 NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,514...16,752,292 		JBrowse link
acenocoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00269 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00269 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00269 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00269 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00269 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00269
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00269 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00269 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00269 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00269 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00269 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00269 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00269 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00269 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00269 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00269 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00269 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00269 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00269 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00269 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
acetylsalicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C1 aldo-keto reductase family 1, member C1 ISO SMPDB SMP:00083 NCBI chr10:65,580,297...65,594,998
Ensembl chr10:65,576,464...65,678,248 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00083 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,401,810...52,414,903 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00083 NCBI chr12:53,292,530...53,302,850
Ensembl chr12:53,292,526...53,302,993 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00083 NCBI chr12:52,287,174...52,295,873
Ensembl chr12:52,287,160...52,295,871 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00083 NCBI chr12:53,259,867...53,281,127
Ensembl chr12:53,271,583...53,281,123 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00083 NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,859,016...90,907,094 		JBrowse link
G CYP2B6B cytochrome P450 family 2 subfamily B member 6B ISO SMPDB SMP:00083 NCBI chr 6:49,158,175...49,173,872
Ensembl chr 6:49,110,812...49,178,334 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00083 NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,817 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00083 NCBI chr 8:114,016,915...114,035,905
Ensembl chr 8:114,011,304...114,035,357 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00083 NCBI chr14:11,217,125...11,293,018
Ensembl chr14:11,216,978...11,293,410 		JBrowse link
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00083 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433 		JBrowse link
G LOC110255237 cytochrome P450 4F6-like ISO SMPDB SMP:00083 NCBI chr 2:61,893,963...61,917,944
Ensembl chr 2:61,889,495...61,917,929 		JBrowse link
G LOC110256483 carbonyl reductase [NADPH] 1-like ISO SMPDB SMP:00083 NCBI chr13:199,713,741...199,719,535 JBrowse link
G LOC110259329 docosahexaenoic acid omega-hydroxylase CYP4F3-like ISO SMPDB SMP:00083 NCBI chr 2:61,863,378...61,884,717
Ensembl chr 2:61,864,575...61,984,903 		JBrowse link
G LOC110261221 cytochrome P450 2J2-like ISO SMPDB SMP:00083 NCBI chr 6:152,321,816...152,358,179
Ensembl chr 6:152,321,848...152,648,979 		JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00083 NCBI chr 5:87,486,552...87,518,520
Ensembl chr 5:87,486,512...87,518,515 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00083 NCBI chr 2:78,799,446...78,802,281
Ensembl chr 2:78,799,449...78,802,285 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00083 NCBI chr 1:129,514,801...129,524,365
Ensembl chr 1:129,514,346...129,524,313 		JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00083 NCBI chr 6:64,432,187...64,435,328
Ensembl chr 6:64,432,148...64,435,320 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00083
G PTGES prostaglandin E synthase ISO SMPDB SMP:00083 NCBI chr 1:269,911,785...269,924,481
Ensembl chr 1:269,911,789...269,924,462 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00083 NCBI chr17:51,153,151...51,200,515
Ensembl chr17:51,153,154...51,200,300 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00083 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00083 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00083 NCBI chr18:9,717,291...9,886,699
Ensembl chr18:9,717,294...9,886,681 		JBrowse link
alteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00280 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00280 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00280 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00280 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00280 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00280
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00280 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00280 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00280 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00280 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00280 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00280 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00280 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00280 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00280 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00280 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00280 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00280 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00280 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00280 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
anistreplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00281 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00281 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00281 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00281 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00281 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00281
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00281 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00281 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00281 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00281 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00281 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00281 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00281 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00281 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00281 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00281 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00281 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00281 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00281 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00281 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
argatroban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00276 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00276 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00276 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00276 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00276 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00276
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00276 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00276 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00276 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00276 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00276 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00276 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00276 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00276 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00276 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00276 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00276 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00276 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00276 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00276 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
bivalirudin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00277 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00277 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00277 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00277 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00277 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00277
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00277 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00277 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00277 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00277 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00277 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00277 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00277 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00277 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00277 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00277 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00277 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00277 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00277 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00277 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
cilostazol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE4D phosphodiesterase 4D ISO SMPDB SMP:00263 NCBI chr16:37,897,300...39,406,534
Ensembl chr16:37,897,302...39,306,364 		JBrowse link
clopidogrel pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 ISO SMPDB SMP:00260 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO SMPDB SMP:00260 NCBI chr 7:58,779,529...58,786,155
Ensembl chr 7:58,779,475...58,786,100 		JBrowse link
G CYP2B6B cytochrome P450 family 2 subfamily B member 6B ISO SMPDB SMP:00260 NCBI chr 6:49,158,175...49,173,872
Ensembl chr 6:49,110,812...49,178,334 		JBrowse link
G CYP2C49 cytochrome P450 2C49 ISO SMPDB SMP:00260 NCBI chr14:106,571,803...106,612,082
Ensembl chr14:106,285,173...106,612,455 		JBrowse link
G CYP3A22 cytochrome P450 family 3 subfamily A member 22 ISO SMPDB SMP:00260 NCBI chr 3:6,617,256...6,665,179
Ensembl chr 3:6,615,343...6,822,817 		JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00260 NCBI chr13:91,522,754...91,572,195
Ensembl chr13:91,521,817...91,572,005 		JBrowse link
G PON1 paraoxonase 1 ISO SMPDB SMP:00260 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,723 		JBrowse link
clopidogrel pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 ISO SMPDB SMP:00610 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO SMPDB SMP:00610 NCBI chr 7:58,779,529...58,786,155
Ensembl chr 7:58,779,475...58,786,100 		JBrowse link
G CYP2B6B cytochrome P450 family 2 subfamily B member 6B ISO SMPDB SMP:00610 NCBI chr 6:49,158,175...49,173,872
Ensembl chr 6:49,110,812...49,178,334 		JBrowse link
G CYP2C49 cytochrome P450 2C49 ISO SMPDB SMP:00610 NCBI chr14:106,571,803...106,612,082
Ensembl chr14:106,285,173...106,612,455 		JBrowse link
G CYP3A22 cytochrome P450 family 3 subfamily A member 22 ISO SMPDB SMP:00610 NCBI chr 3:6,617,256...6,665,179
Ensembl chr 3:6,615,343...6,822,817 		JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00610 NCBI chr13:91,522,754...91,572,195
Ensembl chr13:91,521,817...91,572,005 		JBrowse link
G PON1 paraoxonase 1 ISO SMPDB SMP:00610 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,723 		JBrowse link
dicoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00270 SMP:00656 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00270 SMP:00656 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00270 SMP:00656 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00270 SMP:00656
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00270 SMP:00656 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00270 SMP:00656 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00270 SMP:00656 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00270 SMP:00656 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00270 SMP:00656 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00270 SMP:00656 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00270 SMP:00656 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00270 SMP:00656 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00270 SMP:00656 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00270 SMP:00656 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00270 SMP:00656 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00270 SMP:00656 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
dipyridamole pharmacodyamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE4D phosphodiesterase 4D ISO SMPDB SMP:00264 NCBI chr16:37,897,300...39,406,534
Ensembl chr16:37,897,302...39,306,364 		JBrowse link
enoxaparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00272 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00272 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00272 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00272 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00272 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00272
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00272 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00272 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00272 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00272 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00272 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00272 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00272 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00272 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00272 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00272 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00272 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00272 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00272 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G SERPINC1 serpin family C member 1 ISO SMPDB SMP:00272 NCBI chr 9:116,181,988...116,193,100
Ensembl chr 9:116,181,670...116,193,201 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00272 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
eptifibatide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00266 NCBI chr12:18,860,739...18,877,381
Ensembl chr12:18,860,739...18,877,381 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00266 NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,514...16,752,292 		JBrowse link
fondaparinux pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00273 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00273 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00273 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00273 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00273 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00273
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00273 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00273 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00273 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00273 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00273 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00273 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00273 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00273 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00273 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00273 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00273 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00273 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00273 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G SERPINC1 serpin family C member 1 ISO SMPDB SMP:00273 NCBI chr 9:116,181,988...116,193,100
Ensembl chr 9:116,181,670...116,193,201 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00273 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
heparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00274 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00274 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00274 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00274 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00274 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00274
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00274 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00274 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00274 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00274 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00274 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00274 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00274 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00274 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00274 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00274 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00274 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00274 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00274 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G SERPINC1 serpin family C member 1 ISO SMPDB SMP:00274 NCBI chr 9:116,181,988...116,193,100
Ensembl chr 9:116,181,670...116,193,201 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00274 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
phenindione pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00655 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00655 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00655 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00655 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00655 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00655
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00655 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00655 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00655 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00655 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00655 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00655 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00655 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00655 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00655 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00655 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00655 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00655 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00655 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00655 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
reteplase pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00285 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00285 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00285 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00285 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00285 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00285
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00285 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00285 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00285 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00285 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00285 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00285 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00285 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00285 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00285 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00285 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00285 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00285 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00285 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00285 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
salicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C1 aldo-keto reductase family 1, member C1 ISO SMPDB SMP:00709 NCBI chr10:65,580,297...65,594,998
Ensembl chr10:65,576,464...65,678,248 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00709 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,401,810...52,414,903 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00709 NCBI chr12:53,292,530...53,302,850
Ensembl chr12:53,292,526...53,302,993 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00709 NCBI chr12:52,287,174...52,295,873
Ensembl chr12:52,287,160...52,295,871 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00709 NCBI chr12:53,259,867...53,281,127
Ensembl chr12:53,271,583...53,281,123 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00709 NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,859,016...90,907,094 		JBrowse link
G CYP2B6B cytochrome P450 family 2 subfamily B member 6B ISO SMPDB SMP:00709 NCBI chr 6:49,158,175...49,173,872
Ensembl chr 6:49,110,812...49,178,334 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00709 NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,817 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00709 NCBI chr 8:114,016,915...114,035,905
Ensembl chr 8:114,011,304...114,035,357 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00709 NCBI chr14:11,217,125...11,293,018
Ensembl chr14:11,216,978...11,293,410 		JBrowse link
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00709 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433 		JBrowse link
G LOC110255237 cytochrome P450 4F6-like ISO SMPDB SMP:00709 NCBI chr 2:61,893,963...61,917,944
Ensembl chr 2:61,889,495...61,917,929 		JBrowse link
G LOC110256483 carbonyl reductase [NADPH] 1-like ISO SMPDB SMP:00709 NCBI chr13:199,713,741...199,719,535 JBrowse link
G LOC110259329 docosahexaenoic acid omega-hydroxylase CYP4F3-like ISO SMPDB SMP:00709 NCBI chr 2:61,863,378...61,884,717
Ensembl chr 2:61,864,575...61,984,903 		JBrowse link
G LOC110261221 cytochrome P450 2J2-like ISO SMPDB SMP:00709 NCBI chr 6:152,321,816...152,358,179
Ensembl chr 6:152,321,848...152,648,979 		JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00709 NCBI chr 5:87,486,552...87,518,520
Ensembl chr 5:87,486,512...87,518,515 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00709 NCBI chr 2:78,799,446...78,802,281
Ensembl chr 2:78,799,449...78,802,285 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00709 NCBI chr 1:129,514,801...129,524,365
Ensembl chr 1:129,514,346...129,524,313 		JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00709 NCBI chr 6:64,432,187...64,435,328
Ensembl chr 6:64,432,148...64,435,320 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00709
G PTGES prostaglandin E synthase ISO SMPDB SMP:00709 NCBI chr 1:269,911,785...269,924,481
Ensembl chr 1:269,911,789...269,924,462 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00709 NCBI chr17:51,153,151...51,200,515
Ensembl chr17:51,153,154...51,200,300 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00709 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00709 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00709 NCBI chr18:9,717,291...9,886,699
Ensembl chr18:9,717,294...9,886,681 		JBrowse link
ticlopidine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00261 NCBI chr13:91,522,754...91,572,195
Ensembl chr13:91,521,817...91,572,005 		JBrowse link
ticlopidine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RY12 purinergic receptor P2Y12 ISO SMPDB SMP:00611 NCBI chr13:91,522,754...91,572,195
Ensembl chr13:91,521,817...91,572,005 		JBrowse link
tirofiban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2B integrin subunit alpha 2b ISO SMPDB SMP:00267 NCBI chr12:18,860,739...18,877,381
Ensembl chr12:18,860,739...18,877,381 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO SMPDB SMP:00267 NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,514...16,752,292 		JBrowse link
warfarin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00268 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00268 NCBI chr11:78,521,760...78,538,256
Ensembl chr11:78,521,598...78,538,258 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00268 NCBI chr17:9,045,990...9,073,552
Ensembl chr17:9,046,002...9,073,520 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00268 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00268 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,292...3,900,762 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00268
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00268 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00268 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00268 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00268 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00268 NCBI chr  X:125,265,330...125,350,853
Ensembl chr  X:125,229,450...125,350,853 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00268 NCBI chr  X:114,218,704...114,250,436
Ensembl chr  X:114,218,707...114,250,429 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00268 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202 		JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00268 NCBI chr 8:74,598,170...74,607,409
Ensembl chr 8:74,595,688...74,607,409 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00268 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00268 NCBI chr 3:59,202,363...59,219,807
Ensembl chr 3:59,202,429...59,218,145 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00268 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00268 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLG plasminogen ISO SMPDB SMP:00268 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB
RGD		 PMID:26287237 RGD:11354881 SMP:00268 NCBI chr 3:17,386,230...17,389,162
Ensembl chr 3:17,386,245...17,389,905 		JBrowse link
warfarin pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:26655108 RGD:11354883 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO RGD PMID:26655108 RGD:11354883 NCBI chr 7:58,779,529...58,786,155
Ensembl chr 7:58,779,475...58,786,100 		JBrowse link
G CYP2C42 cytochrome P450 C42 ISO RGD PMID:26655108 RGD:11354883 NCBI chr14:106,666,445...106,701,809
Ensembl chr14:106,666,419...106,713,121 		JBrowse link
G CYP2C49 cytochrome P450 2C49 ISO RGD PMID:26655108 RGD:11354883 NCBI chr14:106,571,803...106,612,082
Ensembl chr14:106,285,173...106,612,455 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4047
    drug pathway 384
      blood and blood forming organs drug pathway 57
        antithrombotic drug pathway 57
          anticoagulant drug pathway + 25
          antiplatelet drug pathway + 34
          other antithrombotic drug pathway + 21
          thrombolytic drug pathway + 20
paths to the root